Novel Adjuvants for Vaccines

ISSN: 1875-614X (Online)
ISSN: 1871-5230 (Print)


Volume 15, 3 Issues, 2016


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Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Inflammatory and Anti-Allergy Agents

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Editor-in-Chief:
Claudiu T. Supuran
Neurofarba Department
University of Florence
Florence
Italy


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Novel Adjuvants for Vaccines



Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 4(2): 185-191.

Author(s): Giampietro Corradin and Giuseppe Del Giudice.

Affiliation: Department of Biochemistry, University of Lausanne 1066, Epalinges, Switzerland.

Abstract

The review covers basic recent discoveries on the mechanism of action of adjuvants, which have been developed in the last decade. In particular, it focuses on the activation of TOLL like receptors and subsequent release of pro-inflammatory lymphokines (innate immunity), which, in turn, are thought to activate antigen specific responses (adaptive immunity). Given the number of novel adjuvants available to researchers, we limited the scope of the review to those adjuvants which are routinely used in our laboratories and of which we have first hand information.

Keywords:

adjuvant, vaccine, t cell, antibody, delivery, tlr.



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Article Details

Volume: 4
Issue Number: 2
First Page: 185
Last Page: 191
Page Count: 7
DOI: 10.2174/1568014053507113
Price: $58
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