Pro-Inflammatory Cytokines and their Actions on the Metabolic Disturbances Associated with Cancer: Implications in Cachexia

ISSN: 1875-614X (Online)
ISSN: 1871-5230 (Print)


Volume 15, 3 Issues, 2016


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Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Inflammatory and Anti-Allergy Agents

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Editor-in-Chief:
Claudiu T. Supuran
Neurofarba Department
University of Florence
Florence
Italy


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Pro-Inflammatory Cytokines and their Actions on the Metabolic Disturbances Associated with Cancer: Implications in Cachexia



Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 10(4): 275-280.

Author(s): Josep M. Argiles, Miriam Toledo, Francisco J. Lopez-Soriano and Silvia Busquets.

Affiliation: Cancer Research Group,Departament de Bioquimica i Biologia Molecular, Facultat de Biologia,Universitat de Barcelona, Diagonal 645, 08028 Barcelona, Spain.

Abstract

The main aim of the present review is to summarize and evaluate the different molecular mechanisms and catabolic mediators (mainly cytokines) involved in cancer cachexia since they may represent targets for future promising clinical investigations.

Keywords:

TNF-, IL-6, IL-1, TWEAK, myostatin, PIF, transcriptional factors, cancer cachexia, anorexia.



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Article Details

Volume: 10
Issue Number: 4
First Page: 275
Last Page: 280
Page Count: 6
DOI: 10.2174/187152311797928199
Price: $58
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