Computational Strategies for the Development of Novel Small Molecule Rheumatoid Arthritis Therapies

ISSN: 1875-614X (Online)
ISSN: 1871-5230 (Print)


Volume 15, 3 Issues, 2016


Download PDF Flyer




Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Inflammatory and Anti-Allergy Agents

This journal supports open access

Aims & ScopeAbstracted/Indexed in


Submit Abstracts Online Submit Manuscripts Online

Editor-in-Chief:
Claudiu T. Supuran
Neurofarba Department
University of Florence
Florence
Italy


View Full Editorial Board

Subscribe Purchase Articles Order Reprints


Computational Strategies for the Development of Novel Small Molecule Rheumatoid Arthritis Therapies



Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 10(2): 85-91.

Author(s): Tarek M. Mahfouz and David H Kinder.

Affiliation: Department of Pharmaceutical and Biomedical Sciences, Raabe College of Pharmacy, Ohio Northern University, Ada, OH 45810, USA.

Abstract

Rheumatoid arthritis is a chronic autoimmune disorder that causes joint disfigurement and destruction leading to reduced quality of life. Effective drug therapies include the Disease Modifying Anti-Rheumatic Drugs which can help impede the progression of the disease but are not always effective. It is, therefore important to identify novel and effective therapies to combat this debilitating disorder. Several bioinformatics tools and computational approaches can be utilized to identify novel and effective therapies for rheumatoid arthritis and these are presented here.

Keywords:

Drug design, rheumatoid arthritis, ADME, comparative modeling, interleukins, DMARDs, autoimmune, Anti-Rheumatic Drugs, prostaglandins, interleukin.



Purchase Online Order Reprints Order Eprints Rights and Permissions




Article Details

Volume: 10
Issue Number: 2
First Page: 85
Last Page: 91
Page Count: 7
DOI: 10.2174/1871523011107020085
Price: $58
Advertisement

Related Journals




Webmaster Contact: urooj@benthamscience.org Copyright © 2016 Bentham Science