Anti-Inflammatory Agents in Ageing and Age-Associated Diseases

ISSN: 1875-614X (Online)
ISSN: 1871-5230 (Print)


Volume 15, 3 Issues, 2016


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Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Inflammatory and Anti-Allergy Agents

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Editor-in-Chief:
Claudiu T. Supuran
Neurofarba Department
University of Florence
Florence
Italy


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Anti-Inflammatory Agents in Ageing and Age-Associated Diseases



Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 5(4): 365-373.

Author(s): S. Bonovas and N M Sitaras.

Affiliation: Department of Pharmacology,School of Medicine, University of Athens, 75, Mikras Asias Str., 115 27 Athens,Greece.

Abstract

Ageing and inflammation might be considered as natural partners. Numerous mechanisms of an inflammatory basis for several age-associated diseases have been identified. Some markers of inflammation are already being integrated into clinical medicine. Furthermore, existent anti-inflammatory drugs and novel candidates have been found to specifically target inflammation pathways in the ageing processes. In this review, we focus on the current knowledge on the field, from the molecular and cellular level to the therapeutic potential of anti-inflammatory agents. First, we present several theories of ageing, in order to explore the involvement of inflammation and to define targets of intervention. Then, we discuss the current approaches and applications as well as the future trends in research regarding the involvement of antiinflammatory agents in the ageing processes.

Keywords:

Ageing, anti-inflammatory agents, inflammation.



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Article Details

Volume: 5
Issue Number: 4
First Page: 365
Last Page: 373
Page Count: 9
DOI: 10.2174/187152306778772856
Price: $58
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