Antiviral Sesqui-, Di- and Sesterterpenes

ISSN: 2211-3533 (Online)
ISSN: 2211-3525 (Print)

Volume 14, 2 Issues, 2016

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Anti-Infective Agents

Formerly: Anti-Infective Agents in Medicinal Chemistry

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Antiviral Sesqui-, Di- and Sesterterpenes

Anti-Infective Agents, 8(3): 169-192.

Author(s): T. Rezanka, L. Siristova and K Sigler.

Affiliation: correspondence to this author at the Institute of Microbiology, Academy of Sciences of the Czech Republic, Videnska.


Terpenoids, biosynthetically related ubiquitous compounds found in virtually all living organisms from marine invertebrates to blooming plants, are derived from the same precursor but their structures and biological and/or pharmacological activities are widely different. Our review concerns terpenoid compounds with antiviral activities, from the simplest sesquiterpenes to diterpenes and sesterterpenes. They include commercially produced therapeutics, compounds with documented antiviral effects and potential future medical use, as well as substances in different stages of clinical research and testing. All of them are based on natural compounds, with only partial man-made changes in the basic structure or mere substituent modifications.


Terpenoids, natural compounds, Sesterterpenes, Antiviral, pharmacological activities.

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Article Details

Volume: 8
Issue Number: 3
First Page: 169
Last Page: 192
Page Count: 24
DOI: 10.2174/187152109788680225
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