New Approaches to Develop Anti-Staphylococcal Agents

ISSN: 2211-3533 (Online)
ISSN: 2211-3525 (Print)

Volume 14, 2 Issues, 2016

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Anti-Infective Agents

Formerly: Anti-Infective Agents in Medicinal Chemistry

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New Approaches to Develop Anti-Staphylococcal Agents

Anti-Infective Agents, 3(4): 267-278.

Author(s): Lei Pei.

Affiliation: GRJ 504, 55 Fruit Street,Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA 02114, USA.


Staphylococci are important pathogens of nosocomial infections and foreign body associated infections. Although anti-microbial agents have played important roles in modern medicine and are well developed, antibiotic resistance of microorganisms has increased rapidly, shortening the useful lifetimes of currently available agents. Taking into account that the first clinical isolate of vancomycin resistant Staphylococcus aureus (VRSA) was reported in the United States in 2002, it is urgent that new anti-microbial agents should be developed to deal with this circumstance. In this paper, some novel approaches to develop anti-staphylococcal agents will be reviewed.


staphylococci, pathogens, streptomyces spp, antimicrobial.

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Article Details

Volume: 3
Issue Number: 4
First Page: 267
Last Page: 278
Page Count: 12
DOI: 10.2174/1568012043353720
Price: $58
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