Cationic Surfactants and Lipids as Anti-Infective Agents

ISSN: 2211-3533 (Online)
ISSN: 2211-3525 (Print)

Volume 15, 2 Issues, 2017

Download PDF Flyer

Anti-Infective Agents

Formerly: Anti-Infective Agents in Medicinal Chemistry

This journal supports open access

Aims & ScopeAbstracted/Indexed in

Submit Abstracts Online Submit Manuscripts Online

View Full Editorial Board

Subscribe Purchase Articles Order Reprints

Cationic Surfactants and Lipids as Anti-Infective Agents

Anti-Infective Agents, 5(1): 33-51.

Author(s): Ana M. Carmona-Ribeiro, Debora B. Vieira and Nilton Lincopan.

Affiliation: Departamento de Bioquímica, Instituto de Quimica, Universidade de Sao Paulo, Caixa Postal 26077, CEP05513-970, Sao Paulo, Brazil.


Surfactants in general are well known for their ability of disrupting cell membranes and damaging microbes. However, cationic surfactants and lipids exhibit interesting additional properties because they can easily be targeted to oppositely charged biological structures such as cells or biomolecules of interest. This review emphasizes physicochemical and antimicrobial properties of cationic lipids and surfactants aiming at the establishment of structure-activity relationships. In special, cationic lipids forming bilayers revealed multiple abilities to carry antibiotics, drugs, genes, and antigens sometimes exhibiting synergic effects with the drug carried or displaying anti-infective properties by themselves.


Antimicrobial activity, cationic amphiphiles, cationic lipids, cell lysis, positive charge-antimicrobial activity relationship.

Download Free Order Reprints Order Eprints Rights and Permissions

Article Details

Volume: 5
Issue Number: 1
First Page: 33
Last Page: 51
Page Count: 19
DOI: 10.2174/187152106774755572

Related Journals

Webmaster Contact: Copyright © 2016 Bentham Science