Natural Products: Promising Resources for Cancer Drug Discovery

ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)


Volume 16, 12 Issues, 2016


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Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

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  • 27th of 59 in Chemistry, Medicinal

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Editor-in-Chief:
Michelle Prudhomme
Universite Blaise Pascal - C.N.R.S
Aubiere Cedex
France


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Natural Products: Promising Resources for Cancer Drug Discovery



Anti-Cancer Agents in Medicinal Chemistry, 12(1): 49-75.

Author(s): Susmita Mondal, Santu Bandyopadhyay, Mrinal K. Ghosh, Sibabrata Mukhopadhyay, Siddhartha Roy and Chitra Mandal.

Affiliation: CSIR-Indian Institute of Chemical Biology, 4, Raja S.C. Mullick Road, Kolkata-700 032, India.

Abstract

Natural products are important sources of anti-cancer lead molecules. Many successful anti-cancer drugs are natural products or their analogues. Many more are under clinical trials. The present review focuses on chemopreventive and anti-cancer activities of polar and non-polar extracts, semi purified fractions and pure molecules from terrestrial plants of India reported between 2005 and 2010 emphasizing possible mechanisms of action of pure molecules.

Keywords:

Apoptosis, Chemoprevention, Immunotherapy, Lead molecule, Medicinal plants, CHEMOTHERAPEUTIC, multi-cellular, Neaoplastic cells, Azadirchta Indica, metabolic engineering.



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Article Details

Volume: 12
Issue Number: 1
First Page: 49
Last Page: 75
Page Count: 27
DOI: 10.2174/187152012798764697
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