Antifolates - Past, Present and Future

ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)


Volume 16, 12 Issues, 2016


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Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

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Ranking and Category:
  • 27th of 59 in Chemistry, Medicinal

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Editor-in-Chief:
Michelle Prudhomme
Universite Blaise Pascal - C.N.R.S
Aubiere Cedex
France


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Current: 2.722
5 - Year: 2.849

Antifolates - Past, Present and Future



Anti-Cancer Agents in Medicinal Chemistry, 4(5): 405-410.

Author(s): Aleem Gangjee and Hiteshkumar D Jain.

Affiliation: Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania 15282.

Abstract

This short perspective briefly covers selected aspects of the past, present and future of antifolates in chemotherapy. Both classical and nonclassical analogs currently in the preclinical stage and clinically used agents are covered.

Keywords:

thymidylate synthase (ts), dihydrofolate reductase (dhfr), antifolates, classical, nonclassical, inhibitors.



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Article Details

Volume: 4
Issue Number: 5
First Page: 405
Last Page: 410
Page Count: 6
DOI: 10.2174/1568011043352803
Price: $58
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