Natural Products: Promising Resources for Cancer Drug Discovery

ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)

Volume 16, 12 Issues, 2016

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Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

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  • 27th of 59 in Chemistry, Medicinal

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Michelle Prudhomme
Universite Blaise Pascal - C.N.R.S
Aubiere Cedex

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Natural Products: Promising Resources for Cancer Drug Discovery

Anti-Cancer Agents in Medicinal Chemistry, 12(1): 49-75.

Author(s): Susmita Mondal, Santu Bandyopadhyay, Mrinal K. Ghosh, Sibabrata Mukhopadhyay, Siddhartha Roy and Chitra Mandal.

Affiliation: CSIR-Indian Institute of Chemical Biology, 4, Raja S.C. Mullick Road, Kolkata-700 032, India.


Natural products are important sources of anti-cancer lead molecules. Many successful anti-cancer drugs are natural products or their analogues. Many more are under clinical trials. The present review focuses on chemopreventive and anti-cancer activities of polar and non-polar extracts, semi purified fractions and pure molecules from terrestrial plants of India reported between 2005 and 2010 emphasizing possible mechanisms of action of pure molecules.


Apoptosis, Chemoprevention, Immunotherapy, Lead molecule, Medicinal plants, CHEMOTHERAPEUTIC, multi-cellular, Neaoplastic cells, Azadirchta Indica, metabolic engineering.

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Article Details

Volume: 12
Issue Number: 1
First Page: 49
Last Page: 75
Page Count: 27
DOI: 10.2174/187152012798764697

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