Role of Stem Cells in Normal Liver and Cancer

ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)

Volume 17, 14 Issues, 2017

Download PDF Flyer

Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

This journal supports open access

Aims & ScopeAbstracted/Indexed in

Ranking and Category:
  • 27th of 59 in Chemistry, Medicinal

Submit Abstracts Online Submit Manuscripts Online

Michelle Prudhomme
Institut de Chimie de Clermont-Ferrand
Université Clermont Auvergne

View Full Editorial Board

Subscribe Purchase Articles Order Reprints

Current: 2.722
5 - Year: 2.849

Role of Stem Cells in Normal Liver and Cancer

Anti-Cancer Agents in Medicinal Chemistry, 11(6): 522-528.

Author(s): Chi Keung Lau, Zhen Fan Yang and Sheung Tat Fan.

Affiliation: Department of Surgery, The University of Hong Kong, 21 Sassoon Road, Hong Kong.


Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related mortality in the world because current treatments, including both surgical and non-surgical ones, cannot effectively cure this disease. Increasing evidence has revealed the importance of cancer stem cells (CSCs) in hepatocarcinogenesis, and the idea of targeting CSCs sheds light on more effective therapeutic strategies for HCC. In this review, normal stem cells and putative CSCs in the liver are briefly introduced. Studies about signaling pathways that regulate pathophysiological activities of liver CSCs and the therapeutic potential by targeting CSCs are also summarized and discussed.


Normal stem cells, cancer stem cells, hepatocellular carcinoma, Epidemiology, chemoembolization, angiogenesis, hydrolase, EpCAM, CD13, CD90, NOTCH, OVAL CELLS, PTEN, TGF.

Purchase Online Order Reprints Order Eprints Rights and Permissions

Article Details

Volume: 11
Issue Number: 6
First Page: 522
Last Page: 528
Page Count: 7
DOI: 10.2174/187152011796011091
Price: $58
Global Biotechnology Congress 2017Drug Discovery and Therapy World Congress 2017

Related Journals

Related eBooks

Webmaster Contact: Copyright © 2017 Bentham Science