Cytotoxic Anticancer Candidates from Terrestrial Plants

ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)

Volume 16, 12 Issues, 2016

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Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

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Michelle Prudhomme
Universite Blaise Pascal - C.N.R.S
Aubiere Cedex

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Cytotoxic Anticancer Candidates from Terrestrial Plants

Anti-Cancer Agents in Medicinal Chemistry, 9(8): 913-942.

Author(s): Young-Won Chin, Kee Dong Yoon and Jinwoong Kim.

Affiliation: College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 151-742, Korea.


Naturally occurring cytotoxic compounds have been considered to be a valuable pool of lead compounds in the development of potential anticancer drugs. Currently, some cytotoxic compounds of terrestrial plants are being used as cancer therapeutic drugs and more candidates are under clinical trials along with cytotoxic small molecules of terrestrial microorganisms and marine organisms. In the present review, the structures and representative cytotoxicities of new organic small molecules (over 200 molecules) obtained from terrestrial plants between 2001 and 2004 are presented.

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Article Details

Volume: 9
Issue Number: 8
First Page: 913
Last Page: 942
Page Count: 30
DOI: 10.2174/187152009789124664
Price: $58

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