Aromatase: The Enzyme and Its Inhibition

ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)


Volume 16, 12 Issues, 2016


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Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

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  • 27th of 59 in Chemistry, Medicinal

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Editor-in-Chief:
Michelle Prudhomme
Universite Blaise Pascal - C.N.R.S
Aubiere Cedex
France


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Aromatase: The Enzyme and Its Inhibition



Anti-Cancer Agents in Medicinal Chemistry, 9(6): 627-641.

Author(s): Lee Banting and Sabbir Ahmed.

Affiliation: School of Pharmacy and Biomedical Sciences, University of Portsmouth, St. Michael's Building, White Swan Road, Portsmouth PO1 2DT, UK.

Abstract

The genetic control, mechanism of action and inhibition of aromatase for potential therapeutic benefits in the arena of hormone dependent illness continues to be of considerable interest. The work presented here concentrates on recent advances in the mechanistic aspects of the aromatase enzyme and the nature of the chemical entities that lead to its inhibition.

Keywords:

Aromatase, inhibition, enzyme, mechanism, natural products, heterocyclic, inhibitor.



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Article Details

Volume: 9
Issue Number: 6
First Page: 627
Last Page: 641
Page Count: 15
DOI: 10.2174/187152009788680037
Price: $58
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