Analogues of Marine Pyrroloiminoquinone Alkaloids: Synthesis and Antitumor Properties

ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)

Volume 16, 12 Issues, 2016

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Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

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Michelle Prudhomme
Universite Blaise Pascal - C.N.R.S
Aubiere Cedex

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Analogues of Marine Pyrroloiminoquinone Alkaloids: Synthesis and Antitumor Properties

Anti-Cancer Agents in Medicinal Chemistry, 8(8): 910-916.

Author(s): Evelyne Delfourne.

Affiliation: Laboratoire de Synthese et Physicochimie de Molécules d'Interet Biologique, UMR CNRS 5068, Universite Paul Sabatier, 118 route de Narbonne, 31062 Toulouse Cedex 9, France.


Marine organisms provide a valuable source for natural products. In recent years, iminoquinone alkaloids including makaluvamines, isobatzellines, tsitsikammamines and wakayin, have emerged as an essential class of marine metabolites due to their prominent biological activities and unusual ring structures. This review focuses on synthesis and antitumor evaluation of analogues of these products.


Pyrroloiminoquinone, makaluvamine, isobatzelline, tsitsikammamine, wakayin.

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Article Details

Volume: 8
Issue Number: 8
First Page: 910
Last Page: 916
Page Count: 7
DOI: 10.2174/187152008786847710
Price: $58

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