Molecular Targets of Omega-3 Fatty Acids for Cancer Therapy

ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)

Volume 17, 14 Issues, 2017

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Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

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  • 27th of 59 in Chemistry, Medicinal

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Michelle Prudhomme
Institut de Chimie de Clermont-Ferrand
Université Clermont Auvergne

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Review Article

Molecular Targets of Omega-3 Fatty Acids for Cancer Therapy

Anti-Cancer Agents in Medicinal Chemistry, 15(7): 888-895.

Author(s): K. Pandima Devi, T. Rajavel, G. L. Russo, M. Daglia, S. F. Nabavi and S M Nabavi.

Affiliation: Department of Biotechnology, Alagappa University, Karaikudi-630 004, Tamil Nadu, India., Applied Biotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, P.O. Box 19395-5487, Iran.


Nowadays, dietary guidelines acknowledge the therapeutic role of omega-3 polyunsaturated fatty acids, as the most important class of fatty acids, against different human diseases. During the last two decades, the average level of consumption of omega-3 polyunsaturated fatty acids has increased from 0.1 to 0.2 g per day. Omega-3 polyunsaturated fatty acids are a group of long-chain polyunsaturated fatty acids which are identified in different foods such as fatty fish, shellfish, and vegetable oils. A growing body of epidemiological and experimental evidence supports the anticancer effects of omega-3 polyunsaturated fatty acids, which led to the identification of their molecular targets in several cancer models. The present review focuses on the basic evidence supporting the potential applications of omega-3 polyunsaturated fatty acids in cancer therapy.


Anticancer, fish oil, molecular targets, omega-3 polyunsaturated fatty acids.

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Article Details

Volume: 15
Issue Number: 7
First Page: 888
Last Page: 895
Page Count: 8
DOI: 10.2174/1871520615666150424124606
Price: $58

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