Tools For Decision-Making In Older Cancer Patients. Role Of The Comprehensive Geriatric Assessment

ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)

Volume 17, 14 Issues, 2017

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Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

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Michelle Prudhomme
Institut de Chimie de Clermont-Ferrand
Université Clermont Auvergne

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Tools For Decision-Making In Older Cancer Patients. Role Of The Comprehensive Geriatric Assessment

Anti-Cancer Agents in Medicinal Chemistry, 14(5): 651-656.

Author(s): M.J. Molina-Garrido, C. Guillen-Ponce, C. Sanchez Castellano, B. Montero Errasquin, A. Mora-Rufete and AJ Cruz-Jentoft.

Affiliation: Consulta de Cancer en el Anciano, Seccion de Oncologia Medica, Hospital General Virgen de la Luz in Cuenca, Hermandad Donantes de Sangre Street. Cuenca. Spain.


Approximately 60% of cancer incidence and 70% of cancer mortality occurs in individuals older than 65 years. The optimal approach to cancer therapy in older adults is often unclear. Historically, advanced age has been an exclusion criterion in clinical cancer trials, and older adults have been consistently underrepresented. As a result, there is a lack of information about treatment efficacy and tolerability in this population.

Comprehensive Geriatric Assessment (CGA) is one of the most useful tools for the oncologist to make decisions related to older patients diagnosed with cancer. This tool has proved to be very useful to detect many deficits, tolerance to chemotherapy and survival in such patients. In this review, we analyze the role of CGA in decision making in geriatric oncology.


Cancer, chemotherapy, cognitive status, comorbidity, comprehensive geriatric assessment, depression, frailty, functional status, geriatric syndromes, instrumental activities of daily live, making decisions, multidisciplinary assessment, older, quality of life, vulnerability.

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Article Details

Volume: 14
Issue Number: 5
First Page: 651
Last Page: 656
Page Count: 6
DOI: 10.2174/1871520614999140416143258
Price: $58

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