Is Effective and Safe a Radiochemotherapy Approach in Elderly Cancer Patients? A Review

ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)

Volume 17, 14 Issues, 2017

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Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

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Michelle Prudhomme
Institut de Chimie de Clermont-Ferrand
Université Clermont Auvergne

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Is Effective and Safe a Radiochemotherapy Approach in Elderly Cancer Patients? A Review

Anti-Cancer Agents in Medicinal Chemistry, 13(9): 1430-1437.

Author(s): Francesco Fiorica, Antonio Zanghì, Giuliana Pascale, Otilia Nuta, Lino Del Pup, Antonio Stefanelli and Francesco Cartei.

Affiliation: Department of Radiation Oncology, University Hospital Ferrara, Italy


Although more than 60% of all cancer patients in Europe and the USA are older than 65 years at the time of diagnosis, elderly patients are generally under-represented in clinical trials. A general consensus on how to treat elderly patients is still far from being achieved.

In this review, we address some of the issues and challenges surrounding the treatment of older cancer patients and radiochemotherapy. We discuss the existing evidence related to radiochemotherapy in the elderly, focusing primarily on the malignancies most commonly seen in older patients and making general treatment recommendations where applicable.


Radiochemotherapy, elderly patients, geriatric oncology, clinical trials.

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Article Details

Volume: 13
Issue Number: 9
First Page: 1430
Last Page: 1437
Page Count: 8
DOI: 10.2174/18715206113136660354
Price: $58

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