Pomegranate Extracts and Cancer Prevention: Molecular and Cellular Activities

ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)

Volume 17, 14 Issues, 2017

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Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

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  • 27th of 59 in Chemistry, Medicinal

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Michelle Prudhomme
Institut de Chimie de Clermont-Ferrand
Université Clermont Auvergne

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Pomegranate Extracts and Cancer Prevention: Molecular and Cellular Activities

Anti-Cancer Agents in Medicinal Chemistry, 13(8): 1149-1161.

Author(s): Deeba N. Syed, Jean-Christopher Chamcheu, Vaqar M. Adhami and Hasan Mukhtar.

Affiliation: Department of Dermatology, University of Wisconsin, Madison, Medical Sciences Center, Room #B25, 1300 University Avenue, Madison, WI 53706, USA.


There is increased appreciation by the scientific community that dietary phytochemicals can be potential weapons in the fight against cancer. Emerging data has provided new insights into the molecular and cellular framework needed to establish novel mechanism-based strategies for cancer prevention by selective bioactive food components. The unique chemical composition of the pomegranate fruit, rich in antioxidant tannins and flavonoids has drawn the attention of many investigators. Polyphenol rich fractions derived from the pomegranate fruit have been studied for their potential chemopreventive and/or cancer therapeutic effects in several animal models. Although data from in vitro and in vivo studies look convincing, well designed clinical trials in humans are needed to ascertain whether pomegranate can become part of our armamentarium against cancer. This review summarizes the available literature on the effects of pomegranate against various cancers.


Pomegranate extracts, cancer prevention .

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Article Details

Volume: 13
Issue Number: 8
First Page: 1149
Last Page: 1161
Page Count: 13
DOI: 10.2174/1871520611313080003
Price: $58
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