Regulation of Cell Death and Survival by Resveratrol: Implications for Cancer Therapy

ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)

Volume 16, 12 Issues, 2016

Download PDF Flyer

Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

Aims & ScopeAbstracted/Indexed in

Ranking and Category:
  • 27th of 59 in Chemistry, Medicinal

Submit Abstracts Online Submit Manuscripts Online

Michelle Prudhomme
Universite Blaise Pascal - C.N.R.S
Aubiere Cedex

View Full Editorial Board

Subscribe Purchase Articles Order Reprints

Current: 2.722
5 - Year: 2.849

Regulation of Cell Death and Survival by Resveratrol: Implications for Cancer Therapy

Anti-Cancer Agents in Medicinal Chemistry, 12(8): 874-879.

Author(s): Simone Fulda.

Affiliation: Institute for Experimental Cancer Research in Pediatrics, Goethe-University Frankfurt, Komturstr. 3a, 60528 Frankfurt, Germany.


Apoptosis is a critical regulatory mechanism to control tissue homeostasis. Accordingly, too little apoptosis can contribute to cancer. Natural compounds, e.g. polyphenols such as resveratrol, have emerged as promising agents for cancer chemoprevention and therapy, since they interfere with various major signaling cascades that are aberrantly regulated in cancers. For example, resveratrol can antagonize signaling events that prevent apoptosis or support cancer proliferation. Further elucidation of the signaling events that are regulated by resveratrol is anticipated to path the way for the transfer of resveratrol and its derivatives into clinical application for chemoprevention or treatment of human cancers.


Apoptosis, Cancer, Cancer therapy, Resveratrol, Signaling, cell death, preventapoptosis, antitumor, apoptotic cell death, membranestimulates, oligomerization, mitochondrial.

Purchase Online Order Reprints Order Eprints Rights and Permissions

Article Details

Volume: 12
Issue Number: 8
First Page: 874
Last Page: 879
Page Count: 6
DOI: 10.2174/187152012802650129
Price: $58

Related Journals

Webmaster Contact: Copyright © 2016 Bentham Science