Editorial Board ::: Anti-Cancer Agents in Medicinal Chemistry

ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)


Volume 16, 12 Issues, 2016


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Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

This journal supports open access

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Ranking and Category:
  • 27th of 59 in Chemistry, Medicinal

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Editor-in-Chief:
Michelle Prudhomme
Universite Blaise Pascal - C.N.R.S
Aubiere Cedex
France


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Editorial Board

Editor-in-Chief:

Michelle Prudhomme (Biography
Michelle Prudhomme

Prof. Michelle Prudhomme holds the position of Emeritus Professor at the Blaise Pascal University of Clermont-Ferrand, France. She was awarded Doctor-Engineer degree at the University of Caen France where her research focused on the synthesis of sulfur compounds. Then she received her Ph.D. Degree at the University of Clermont-Ferrand, France, after works on antibiotics. She developed projects related to drug design and discovery of cytotoxic compounds. She has authored or co-authored 108 research and review articles and and 6 patents.

Dr. Michelle Prudhomme was the founding Editor (2000) and is currently the Editor-in-Chief of this journal (Anti-Cancer Agents in Medicinal Chemistry), published by Bentham Science Publishers.

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Universite Blaise Pascal - C.N.R.S
Aubiere Cedex
France



Associate Editor(s):

Jeanny B. Aragon-Ching
INOVA Comprehensive and Cancer Research Institute
Fairfax, VA
USA

Lidia Matesic (Biography
Lidia Matesic

Dr. Lidia Matesic completed an undergraduate degree in medicinal chemistry and a PhD in chemistry from the University of Wollongong, Australia. She is currently a Radiochemist at the Australian Nuclear Science and Technology Organisation in Sydney, Australia. Her research focusses on the development of new radiopharmaceuticals for the diagnosis and treatment of diseases such as neurological disorders and cancer.

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Australian Nuclear Science and Technology Organisation
Sydney
Australia

Hai-Liang Zhu (Biography
Hai-Liang Zhu

Hai-Liang Zhu, born in 1965 in China. Achieved his Master degree in 1988, in Department of Chemistry, Lanzhou University, specializing in inorganic chemistry. Worked at Department of Chemistry of Ningxia University as a Lecturer in 1988-1994, Lecturer. Achieved his PhD degree in 1998 at School of Chemistry of Nanjing University, and the research direction is bio-inorganic chemistry. From 1998 to 2002 turned to work at School of Chemistry of Zhongshan University and Department of Chemistry of Philipps-University Marburg in Germany as a postdoc. Started his professorship at School of Life Sciences in Nanjing University from 2004. Now focus his research field at Medicinal Chemistry, and has published more than 600 articles and applied for 160 patents.

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Nanjing University
Nanjing
China

William A. Denny (Biography
William A. Denny

Distinguished Professor Bill Denny holds PhD (synthetic chemistry) and DSc (drug development) degrees from the University of Auckland, New Zealand. He is Director of the Auckland Cancer Society Research Centre at the University of Auckland, and an Adjunct Professor in the School of Chemical Sciences there. He is an author on about 670 scientific publications and is a named inventor on 50 issued U.S. patents. He was a co-founding scientist of Proacta Inc and of Pathway Therapeutics, and was the recipient of the 2014 Medicinal Chemistry Award from the American Chemical Society.

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The University of Auckland
Auckland
New Zealand

Grégoire Prevost
Oncology Research IPSEN
Les Ulis
France

David E. Graves
University of Alabama at Birmingham
Birmingham, AL
USA

Wenbin Zeng (Biography
Wenbin Zeng

Dr. Zeng received his Ph.D in Chemistry from the University of Muenster, Germany. He is appointed as a full professor at Central South University in 2008. Currently he serves as the deputy dean of School of Pharmaceutical Science in Central South University. Dr. Zeng has authored more than 100 peer-reviewed articles. He also served on the Editorial Board of some scientific journals, such as Associated Editor in Anti-cancer Agents in Med Chem, performed peer-review for more than 50 journals, and participated in many grant review panels.

His recent research is focused on the design and synthesis of multimodal molecular imaging biomarker platforms for the diagnosis and treatment of diseases, including cancer and cardiovascular disease.

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Central South University
Changsha
China


Regional Editor(s):

Patrick Dallemagne (Biography
Patrick Dallemagne

Prof Patrick Dallemagne holds a Pharm D and a Ph D in Medicinal Chemistry from the University of Normandy, Caen (France). He became Associate Professor of Medicinal Chemistry at the University of Caen in 1991 and was received Full Professor in 1999. He is currently head of the Centre d’Etudes et de Recherche sur le Médicament de Normandie whose activity is dedicated to drug design in oncology and neurosciences fields.

Prof Patrick Dallemagne has authored more than 120 publications and he applied for numerous patents.

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Université de Caen Basse-Normandie
Cedex
France

Shinji Osada (Biography
Shinji Osada

At March/1993, graduated PhD course of Gifu University School of Medicine and work as surgical staff in same institute from January/2000 after experience as a research fellow in Thomas E Starzl Transplantation Institute, University of Pittsburgh between January/1998 and December/1999.

Area of Interest: Hepato-Pancreatic Biliary Surgery

1. Aggressive hepatectomy for metastatic liver tumor

2. Estimate safety reconstruction method after pancreatoduodenectomy

3. Biochemical approach for cancer chemotherapy or cancer invasion

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School of Medicine, Gifu University
Gifu
Japan

Dominique Delmas (Biography
Dominique Delmas

Dominique Delmas is Professor in the University of Burgundy at the Inserm Research Center Unit U866 “Lipids, Nutrition, Cancers” in Dijon (France) where he manages a research group entitled “Bioactive Molecules and Health”. The main research objectives of his group are to develop and to coordinate multidisciplinary and translational research from laboratory to clinical applications, including 1) the determination of early biomarkers in response to treatment; 2) the identification of new potential targets within membrane and lipid metabolism, 3) the development of new therapeutic strategies by the use of molecules with low toxicity (i.e. polyphenols). These fields constitute a main part of the recent creation by the French Ministery of the LabEx LipSTIC in Dijon.

Dominique Delmas has authored or coauthored over 50 original papers and comprehensive reviews on polyphenols health effects. He has also contributed to over 10 books chapters concerning the molecular mechanisms of polyphenols in tumoral models.

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University of Burgundy, INSERM Research Center
Dijon
France

Isao Okazaki (Biography
Isao Okazaki

Isao Okazaki, M. D., Ph. D. was born in 1941, graduated from Keio University School of Medicine, Tokyo, Japan. He was and is still an Internist, and the specialist of gastrointestinal and liver, gallbladder and pancreas. He is proud of the first finder of collagenase in the liver (Nature, 1974) and published original papers on MMPs in the recovery from liver diseases. He is also interested in the carcinogenesis of nonalcoholic steatohepatitis (Cancer, 2014; J Mod Hum Pathol 2016). He is the Professor of Department of Medicine, Sanno Hospital, International University of Health and Welfare, Tokyo, Japan.

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International University of Health and Welfare, Sanno Hospital
Tokyo
Japan


Section Editor(s):

(Rational Drug Design)
Alexander A. Shtil
N.N. Blokhin Cancer Center
Moscow
Russia


Editorial Board Members:

Raghu R. Akkinepalli
Panjab University
Chandigarh
India

Chantal Autexier (Biography
Chantal Autexier

Chantal Autexier, Ph.D. is a Professor of Anatomy and Cell Biology, and Medicine at McGill University and a Senior Investigator at the Lady Davis Institute for Medical Research of the Jewish General Hospital in Montreal, Canada. Dr. Autexier earned her graduate degree from McGill University and completed postdoctoral training with Dr. Carol Greider at Cold Spring Harbor Laboratory in New York. Dr. Autexier has been recognized for her discoveries in the field of structure and function of telomerase, and published more than 50 scientific publications.

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Lady Davis Institute for Medical Research
Montreal, QC
Canada

M. Berretta (Biography
M. Berretta

Dr. Berretta obtained a doctorate (Ph.D.) in Oncology from the University of Catania, Catania (Italy).

Dr. Berretta is also Editor in Chief of World Cancer Research Journal, published by Verduci-international.

Currently Dr. Berretta is also an Oncologist (MD) at National Cancer Institute of Aviano (PN), Italy. He has published more than 200 scientific publications and 3 books on oncologic topics.

Dr. Berretta is the chief of Cancer survivors on solid tumor at Department of Medical Oncology of National cancer Institute of Aviano (PN), Italy.

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National Cancer Institute, IRCCS
Aviano
Italy

Robert M. Brosh
NIH Biomedical Research Center
Room 06B125
USA

Søren B. Christensen (Biography
Søren B. Christensen

Dr. Brøgger Christensen got a Ph.D. in medicinal chemistry from the Royal Danish School of Pharmacy, which has now been merged with the University of Copenhagen. He has been an associated professor and later professor with special obligations at this University since 1971. Currently he is professor emeritus. His teaching has focused on natural product and his research has focused on drug development from natural products. Two biotech companies have been founded based on his inventions: Lica Pharmaceuticals and GenSpera, now Inspyr Therapeutics. He has co-authored more than 170 scientific publications. He is co-inventor on 10 patents. His h-index is 44.

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University of Copenhagen
Copenhagen
Denmark

Bikash Debnath (Biography
Bikash Debnath

Dr. Bikash Debnath works as a Visiting Assistant Research Scientist in the Department of Medicinal Chemistry, College of Pharmacy at University of Michigan. He received his Ph.D. in Medicinal Chemistry in 2005 from Jadavpur University, Kolkata, India. Over the past 15 years Dr. Debnath is actively involved in the discovery of novel anticancer and anti-HIV agents. He has published more than 40 scientific papers.

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University of Michigan
Ann Arbor
USA

F. Di Benedetto (Biography
F. Di Benedetto

I graduated at Medical School on July 3rd 1995 in Catania, my hometown. Afterwards, I had my Residency in General Surgery in Milan at “Niguarda Ca’ Granda Hospital”, and I spent 4 months at the Liver/Gastro Intestinal Transplant Division, Department of Surgery, University of Miami. Since then, my career was mostly dedicated to the surgical oncology of the hepato-pancreato-biliary district and to liver transplantation, with both clinical and translational interests. From 2008 I am Associate Professor at University of Modena and Reggio Emilia (Modena, Italy), where I currently direct the Hepato-pancreato-biliary Surgery and Liver Transplantation Unit. Robotic surgery, immunosuppressive therapy and regenerative medicine are the research field of interest in our unit.

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University of Modena and Reggio Emilia
Modena
Italy

Isabelle Dussault
Amgen Inc
Thousand Oaks, CA
USA

Marco Folini (Biography
Marco Folini

Dr. Folini obtained the Degree in Biological Sciences and the doctorate (Ph.D.) in Biotechnological Applications from the University of Milan, Italy. Currently Dr. Folini is Staff scientist at the Molecular Pharmacology Unit, Department of Experimental Oncology and Molecular Medicine, National Cancer Institute of Milan. He is member of the American Association for Cancer Research and of the EORTC-Pharmacology and Molecular Mechanism group.

Dr. Folini has authored 65 manuscript (h-index: 28; total impact factor: 330), guest-edited the thematic issue “Targeting Telomere Maintenance Mechanisms in Cancer Therapy” published by Bentham Science Publishers and is a named inventor of 1 patent (WO/2006/087752).

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Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori
Milano
Italy

Barbara Gatto
University of Padova
Padova
Italy

Roy M. Golsteyn (Biography
Roy M. Golsteyn

Dr. Roy Golsteyn is an Associate Professor of Biology and the Director of the Cancer Cell and the Natural Product Laboratories at the University of Lethbridge in Canada. He undertook his PhD in biochemistry in Sir Tim Hunt’s laboratory at the University of Cambridge (Nobel Prize 2001). Dr. Golsteyn completed his studies as a post-doctoral fellow at the ISREC in Switzerland, at the Institute Curie in Paris with Dr. Evelyne Friederich and Prof. Daniel Louvard. Prior to joining the University of Lethbridge, he was a senior research scientist in drug discovery in oncology with the pharmaceutical company Servier in Paris, France. He has published more than 80 papers and holds 5 patents.

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University of Lethbridge
Lethbridge
Canada

Yves Gènisson (Biography
Yves Gènisson

Dr. Génisson completed his PhD at the ICSN in Gif-sur-Yvette, France, under the supervision of Dr. C. Marzano. After working for two years at Merck Frosst in Montreal, Canada, he joined the CNRS in the group of Dr. A. E. Greene in Grenoble, France. In 1998, he moved to Toulouse, France, where he is now the director of the SPCMIB laboratory. President regional board and vice president of the Organic Chemistry Division of the French Chemical Society, he has co-authored more than 68 publications and 2 patents. His scientific interests lie in the field of chiral ionic liquids and bioorganic chemistry of lipids.

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Université Paul Sabatier
Toulouse
France

John W. Ho (Biography
John W. Ho

Professor Wing Shing (John) Ho, Ph.D., is an associate professor in the Biochemistry Programme of School of Life Sciences at The Chinese University of Hong Kong. He obtained a B.S. from The University of Alberta, and M.A., and a Ph.D. in Biological Chemistry (1985) from State University of New York at Buffalo. After completing a post-doctoral training in Pediatrics Department at SUNYAB and University of Utah. He was appointed associate professor in the School of Life Sciences at The Chinese University of Hong Kong in 1994.

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The Chinese University of Hong Kong
Shatin
China

S. Huang (Biography
Hsu-Shan Huang

Dr. Huang obtained a doctorate (Dr. rer. nat.) in Pharmacy (Medicinal Chemistry) from the University of Regensburg, Germany. Dr. Huang was former dean of School of Pharmacy, and head of the Department of Research and Development in NDMC and director of Department of Pharmacy Practice, Tri-Service General Hospital/NDMC. Currently, Dr. Huang is a Professor in College of Medical Science and Technology, Taipei Medical University also an Adjunct Professor in NDMC. He has published more than 90 scientific publications and is a named inventor of 30 issued U.S., Taiwan or other countries patents. Dr. Huang is currently the Editorial Advisory Board of this journal, published by Bentham Science Publishers.

Biography
S. Huang

Dr. Shile Huang focuses on studying the role of mTOR signaling in tumorigenesis and metastasis. Since 2008, he has been studying how mTOR regulates cell survival, cell motility and lymphangiogenesis; how some small molecules (e.g. curcumin, cryptotanshinone, dihydroartimisinin, and ciclopirox) act as anticancer agents and how the heavy metal cadmium induces neuronal apoptosis. He is an editor-in-chief for "Metals and Neurodegeneration". He serves as ad hoc reviewers for funding agencies (e.g. NIH, DOD, ACS, and AHA) and journals (e.g. Cancer research, Oncogene, JBC, etc.).

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LSU Health Sciences Center
Shreveport, LA
USA

Pawel Kafarski (Biography
Pawel Kafarski

Pawel Kafarski was born in 1949 in Gdańsk. After finishing studies in chemistry at Wrocław University of Science and Technology in 1966 he stays at this university defending doctoral thesis (1977), receiving habilitation (1990) and becoming a full profesor (2000). Now he chairs Department of Bioorganic Chemistry. He was staying for nine months at Marquette University, Milwaukee (Wisconsin, U.S.A.) in 1976/1977 and six months at poste rouge at Ecole Nationale Superieure de Chimie de Montpellier (France) in 1989. He promoted 37 PhDs an published over 300 papers, which are cited over 5000 times.

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Wroclaw University of Technology
Wroclaw
Poland

Douglas A. Kinghorn (Biography
Douglas A. Kinghorn

Prof. A. Douglas Kinghorn has been Professor and Jack L. Beal Chair in Natural Products Chemistry and Pharmacognosy at the College of Pharmacy, The Ohio State University (OSU) since 2004. He received Ph.D. (1975) and D.Sc. (1990) degrees from The School of Pharmacy, University of London. He has authored or co-authored over 500 peer-reviewed research articles, review articles, and book chapters. His research interests include the isolation and structural characterization of bioactive natural products from higher plants, particularly potential anticancer agents, antileishmanial compounds, cancer chemopreventives, and taste-modifying substances. In 2016, he received a Distinguished Scholar Award from OSU.

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The Ohio State University
Columbus, OH
USA

Cinzia Lanzi
Molecular Pharmacology Unit
Milan
Italy

Da-Yong Lu
Shanghai University
Shanghai 200444
China

José M. P Martín
Autonomous University of Madrid
Madrid
Spain

Peter E. Nielsen (Biography
Peter E. Nielsen

Peter E. Nielsen is full professor at University of Copenhagen, Denmark since 1995. He is one of the inventors of peptide nucleic acid (PNA) (1991), and has further studied and developed this DNA mimic during the last 25 years in relation to chemistry, origin of life, molecular biology and drug discovery. He is the co-author of more than 400 scientific papers, reviews and books. He is a member of EMBO and the Danish Academy of Technical Sciences, and he has received several national and international scientific prizes including the Novo Nordic Foundation and the Lundbeck prizes.

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University of Copenhagen
Copenhagen
Denmark

Ingo Ott
Technische Universität Braunschweig
Braunschweig
Germany

José Portugal (Biography
José Portugal

José Portugal received his PhD in Biology from the University of Barcelona, Spain in 1983. He was a post-doc at the University of Cambridge, UK (1985-87), and he was appointed Lecturer in Biochemistry at the University of Barcelona (1987-1992). At present, he is Senior Research Scientist at the IBMB-CSIC in Barcelona. His research about the interactions between antitumor drugs and DNA aims to understand the molecular and cellular bases of specific recognition both in vitro and in vivo. He has published over 80 peer-reviewed articles and reviews in journals.

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Instituto de Biologia Molecular de Barcelona
Barcelona, CSIC
Spain

Luigi Quintieri (Biography
Luigi Quintieri

Dr. Luigi Quintieri completed his undergraduate studies in Pharmacy as well as his PhD studies in Oncology at the University of Padova, Italy. Since 2006 he is Assistant Professor at the same University. His areas of research interest include phase I and phase II metabolism of drugs, and the pharmacological characterization of novel inhibitors of glutathione transferase P1-1 for cancer therapy.

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Padua University
Padua
Italy

Joaquín María Campos Rosa
Universidad de Granada
Granada
Spain

Rajeshwar Singh
Naeja Pharmaceutical Inc.
Alberta
Canada

Andrey A. Toropov
IRCCS
Istituto di Ricerche Farmacologiche "Mario Negri"
20156 Milano
Italy

Michael J. Waring
University of Cambridge
Cambridge
UK

Wenfang Xu
Shandong University
Jinan
China

Ruiwen Zhang (Biography
Ruiwen Zhang

Dr. Zhang has extensive expertise and experiences in translational biomedical research, particularly translational medicine, cancer therapy and prevention, pharmacogenomics and therapeutics. He has published more than 210 papers, 2 books, more than 50 invited reviews/book chapters, and more than 180 meeting abstracts. Dr. Zhang has made more than 200 invited presentations. He is a certified toxicologist by the American Board of Toxicology (D.A.B.T.). He is also an editor-in-chief, associate-editor-in-chief, associate editor, or editorial board member of 25 scientific journals. Dr. Zhang has been elected as a Fellow of American Association for the Advancement of Science (AAAS) since 2009.

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Texas Tech University Health Science Center, School of Pharmacy
Amarillo, TX
USA

Kenneth C. Anderson (Biography
Kenneth C. Anderson

Dr. Anderson is the Kraft Family Professor of Medicine at Harvard Medical School as well as Director of the LeBow Institute for Myeloma Therapeutics and Jerome Lipper Multiple Myeloma Center at Dana-Farber Cancer Institute. He is a Doris Duke Distinguished Clinical Research Scientist and American Cancer Society Clinical Research Professor. Over the last three decades, he has developed laboratory and animal models of the tumor in its microenvironment which have allowed for both identification of novel targets and validation of novel targeted therapies. He has then rapidly translated these studies to clinical trials culminating in FDA approval of novel targeted therapies, which have markedly improved patient outcome.

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Dana-Farber Cancer Institute
Boston, MA
USA

Jose C. Basurto (Biography
Jose C. Basurto

Dr José Correa Basurto studied the Master Degree in Bioinformatic at Universidad Internacional de Andalucia-España 2013, he studied PhD in Medicine research 2006, MD in Pharmacology 2004, BS Medicine 2002. He is full professor-research of Pharmacology and Medicinal Chemistry at ESM-IPN, Mexico . Dr Correa had published 115 articles in JCR journals, 6 in no indexed journal, 3 book capters, and also, He had advised 20 posgraduate studens (10 are developing their proyect of thesis) and Dr Correa had receive 4 posdoctoral. Finally, He Had submit 3 patents.

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Escuela Superior de Medicina del IPN
México city
México

Janusz Boratynski (Biography
Janusz Boratynski

Janusz Boratyński received his PhD from the Institute of Immunology and Experimental Therapy, Wrocław Poland. He specializes in the chemical modification of biological macromolecules and their application as drug carriers. One of the ideas put forward by him was the modification of proteins at above 100 °C without the loss of biological activity. Another field of interest are bacteriophage technology. Currently he is a head of the chemical section of the Integrated Laboratory of Experimental Oncology and Innovative GLP Technologies “Neolek”.

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Ludwik Hirszfeld Institute of Immunology & Experimental Therapy of the Polish Academy of Sciences
Wroclaw
Poland

Zhen Cheng (Biography
Zhen Cheng

Dr. Zhen Cheng is an Associate Professor of Radiology and a member of the Molecular Imaging Program at Stanford (MIPS), BioX program, Canary Center at Stanford for Cancer Early Detection and Stanford Cancer Center. He currently is the Director of the Cancer Molecular Imaging Chemistry Laboratory at MIPS where he is developing novel molecular probes, non-invasive imaging techniques, and bionanotechnology for multimodality early detection of diseases including cancer, cardiac and neurological diseases. Dr. Cheng has published over 200 articles, and he has served as a reviewer for numerous funding agencies and for over 100 research journals.

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Stanford University
Stanford, CA
USA

A. Conejo-García (Biography
A. Conejo-García

Ana Conejo-García was born in Malaga, Spain in 1975. She received the degree in Pharmacy in 1998 from the University of Granada (Spain) and the Ph. D. in Pharmacy from the same University in 2002. She jointed Prof. Schofield's group (2003-2005) at University of Oxford as a postdoctoral Marie Curie Fellow. From 2006 she works as a lecturer in the Department of Medicinal and Organic Chemistry of the University of Granada. She is specialized in studying mechanisms that regulate proliferation, differentiation and cellular apoptosis and searching for new therapeutic strategies based on the rational design of highly selective antitumor agents.

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Universidad de Granada
Granada
Spain

Francesca Degrassi
Università "La Sapienza"
Roma
Italy

Gene M. Dubowchik
Bristol-Myers Squibb Pharm. Res. Inst.
Wallingford, CT
USA

Mohammed El-Gamal
University of Sharjah
Sharjah
United Arab Emirates

Keith R. Fox
University of Southampton
Southampton
UK

Sylviane Giorgi-Renault
Université Paris Descartes
Paris
France

Vita M. Golubovskaya (Biography
Vita M. Golubovskaya

Dr. Vita Golubovskaya is a Director of Research and Business Development at Promab Biotechnology developing novel anti-cancer immunotherapies including CAR-T therapy. She has more than 20 years of experience in cancer research, oncology and immunology. Previously, Dr. Golubovskaya was Research Associate Professor at Roswell Park Cancer Institute and Research Professor at University of Buffalo, SUNY, Buffalo, NY. She holds Ph.D from Institute of Cytology, St. Petersburg, Russia. Dr. Golubovskaya authored more than 75 manuscripts, 8 patents and several book chapters. She was awarded as a Principal Investigator Susan Komen Grant, NCI NIH grants as Co-Investigator and STTR grant as PI. Dr. Golubovskaya served as a Guest Editor in Frontiers in Bioscience, Anti-Cancer Agents in Medicinal Chemistry and Cancers.

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Roswell Park Cancer Institute
Buffalo, NY
USA

Petr Heneberg
Charles University in Prague
Prague
Czech Republic

Steven N. Hochwald
Roswell Park Cancer Institute
New York
USA

Marc A. Ilies
Temple University School of Pharmacy
Philadelphia, PA
USA

Benny A. Kaipparettu (Biography
Benny A. Kaipparettu

Dr. Kaipparettu is an Assistant Professor in the Department of Molecular and Human Genetics at Baylor College of Medicine and research member of Dan L Duncan Cancer Center at Baylor. His major research area is mitochondria-nuclear crosstalk in cancer progression and metastasis (https://sites.google.com/site/kaipparettulab/ ). The lab use transmitochondrial cybrid models to compare mitochondria from different sources under a common nuclear background. His lab also focus on the development of nano materials for Bioimaging.

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Baylor College of Medicine
Houston, TX
USA

Rene Kizek
Mendel University of Agriculture and Forestry
Brno
Czech Republic

F. Liang (Biography
F. Liang

Feng Liang earned his Ph.D. in Organic Chemistry in 2003 at Wuhan University in China, and took his first faculty position at the same University in 2004. He moved to Arizona State University (USA) in 2006, where he was an assistant research scientist at the BioDesign Institute. In 2012, he joined Wuhan University of Science and Technology in China, where he is currently a ‘‘Xiang-Tao’’ Special Term Professor. His main research interests include: 1) Smart Molecules and Materials for Cancer Theranostics; 2) Bio and Chemical Sensors; 3) Recognition-based Single Biopolymer Sequencing.

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Wuhan University of Science and Technology
Hubei 430081
China

X. M. Yuan (Biography
X. M. Yuan

Dr. Xi-Ming Yuan received his M.D. in 1984 from Jilin Medical College in China and a Ph.D. degree in internal medicine 1997 from Linkoping University, Sweden. Year 2006 he has been appointed Associate Professor in Experimental Pathology by Faculty of Medicine and Health Sciences, Linköping University. HeDeare has published more than 70 scientific publications in SCI that are cited > 2000 times with a h-index 25.

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Linköping University
Linköping
Sweden

Faustino Mollinedo (Biography
Faustino Mollinedo

Faustino Mollinedo received his Ph.D. in Chemistry in 1982 (Complutense University, Madrid). He then moved to Dartmouth Medical School in Donald L. Schneider’s laboratory (1982-3), where they identified a novel cytoplasmic granule (tertiary granule) in human neutrophils, and then to New York University Medical Center. In 1986 he obtained a tenure position at the Spanish National Research Council, establishing successively his laboratory in Madrid, Valladolid and Salamanca. Now he has moved to the Center for Biological Research in Madrid (2016). His laboratory has made several important contributions in neutrophil biology, ether lipids’ mechanism of action, and apoptosis as a target in cancer therapy. His laboratory identified the translocation of Fas/CD95 death receptor into lipid raft membrane domains as a new mechanism of apoptosis regulation, unveiling rafts as a new target in cancer therapy.

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Consejo Superior de Investigaciones Científicas (CSIC)
Madrid
Spain

Jozef Oleksyszyn
Politechnika Wrocławska
Wroclaw
Poland

Don R. Phillips (Biography
Don R. Phillips

Professor Phillips obtained his doctorate in Physical Chemistry from the University of Adelaide (South Australia, Australia). He joined the Department of Biochemistry at La Trobe University (Victoria, Australia) in 1972 where he initiated and was Head of the Anticancer Drug Design and Development Laboratory. He was awarded a Personal Chair in 2004 and the position of Emeritus Professor in 2010. He has published 150 research articles and 15 book chapters on anticancer drug mechanism of action and drug design.

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Department of Biochemistry and Genetics,La Trobe University
Victoria
Australia

Edwin M. Posadas
Samuel Oschin Comprehensive Cancer Institute
Los Angeles, CA
USA

Laura Rodríguez Raurell (Biography
Laura Rodríguez Raurell

I am Associate professor at the University of Barcelona since 2012. I am the responsible of the Supra- and Nanostructured Systems and we are mainly interested on the synthesis and characterization of novel water soluble supramolecular structures that are luminescent and present different properties, being the formation of gels, vesicles, biological activity and metallic nanostructures among others. We have national and European funding and we are an active group involved in several European COST Actions and regular participation in national and international conferences.

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Universitat de Barcelona
Barcelona
Spain

Emil Rudolf (Biography
Emil Rudolf

Dr. Rudolf obtained his Ph.D. in Medical biology from the Charles University, Faculty of Medicine in Hradec Kralove. Currently, Dr. Rudolf is Full Professor and head of Department of Medial biology and genetics in the Charles University, Faculty of Medicine. He has authored more than 70 scientific papers and 7 chapters in books.

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Charles University in Prague
Hradec Králové
Czech Republic

Rosario M. Sánchez-Martin
University of Granada
Granada
Spain

Yusuf Tutar (Biography
Yusuf Tutar

Dr. Yusuf TUTAR is the Head of Biochemistry Division and the Head of Basic Sciences Department at Faculty of Pharmacy, Cumhuriyet University, Sivas Turkey. Dr. Tutar is also the Head of Biomedical Engineering Program at the same university. He obtained his M.Sc. and Ph.D. at Oregon State University and Texas Tech University respectively. He pursued his postdoctoral study at National Institutes of Health (NIH/NIDDK), USA. His research focuses on Biochemistry, Biophysics, Genetics, and Molecular Biology with specialization in the fields of protein structure-function, protein folding, prion, microrna, pseudogenes, molecular cancer, proteomics, genomics, protein expression and characterization by spectroscopic and calorimetric methods.

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Cumhuriyet University
Sivas
Turkey

Jean-Yves Winum (Biography
Jean-Yves Winum

Dr. Winum received his PhD in chemistry from the University of Montpellier (France), in 1998. He then worked as a postdoctoral fellow in the Chemistry Department of Georgetown University (Washington, DC) and in the Organic Chemistry Department of the University of Geneva (Switzerland). In 1999, he joined the Department of Chemistry of the University of Montpellier, where he is now an Associate Professor. He has published more than 135 scientific papers and is a named inventor of 6 patents. He is also regional editor of Recent Patents in Anti-cancer Drug Discovery, associate editor of Journal of Enzyme Inhibition and Medicinal Chemistry, and editorial board member of Expert Opinion on Therapeutic Patents, and Current Organic Chemistry.

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University of Montpellier
Montpellier
France

Jari Yli-Kauhaluoma
University of Helsinki
Helsinki
Finland

Yingjie Zhang (Biography
Yingjie Zhang

Dr. Yingjie obtained a doctorate (Ph.D.) in Medicinal Chemistry from Shandong University, China in 2012. After that, Dr. Yingjie became a faculty member in Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University. Dr. Yingjie’s research interests focus on rational design, synthesis and biological evaluation of compounds targeting histone deacetylases (HDACs), aminopeptidase (AP) and kinds of protein kinases. Dr. Yingjie has published more than 40 scientific publications. Dr. Yingjie is also a teaching member of national excellent open course《Drug Design》.

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Shandong University
Jinan
China

Neville J. Anthony
Merck Research Laboratories
West Point, PA
USA

R. Bei
University of Rome "Tor Vergata"
Rome
Italy

Viktor Brabec (Biography
Viktor Brabec

Dr. Brabec is Head of the Department of Molecular Biophysics and Pharmacology of the Institute of Biophysics, Academy of Sciences of the Czech Republic and professor of biophysics at the Palacky University in Olomouc. His experience in the research is aimed at structure, physical properties and interactions of biomacromolecules including mechanisms underlying activity of anticancer and antimicrobial drugs. Dr. Brabec has authored more than 300 full-length articles published in refereed international journals; these papers have been cited more than 10 000 times (Hirsch‘s index, h = 54), 8 review chapters and is currently member of the editorial board of three foreign international journals.

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University of Palacky
Olomouc
Czech Republic

John Chirgwin (Biography
John Chirgwin

John Chirgwin, PhD, is Professor of Medicine at Indiana University, with previous appointments at Washington University and the Universities of Texas and Virginia. Widely cited for the original method of RNA isolation with guanidinium thiocyanate, he has been successively a biochemist, molecular biologist, cell biologist and cancer researcher. His laboratory recently developed high-throughput ex vivo assays for drugs targeting cancer:bone interactions in breast & prostate cancer and multiple myeloma, screening inhibitors of the proteasome, heparanase, FGFs, TGFβ, uPAR, PTHrP and Sema4D. The assays are being extended to fat, muscle and sensory neurons to model cachexia and cancer bone pain.

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Indiana University School of Medicine
Indianapolis, IN
USA

Peter Daniel
Humboldt University
Berlin
Germany

A. Desideri
University of Rome Tor Vergata, Via Della Ricerca Scientifica
Rome 00133
Italy

Prof Sylvie Ducki
ENSCCF, Institut de Chimie de Clermont-Ferrand
Aubiere
France

José J. Fernández
University of La Laguna
La Laguna
Spain

Aleem Gangjee (Biography
Aleem Gangjee

Dr. Gangjee obtained a doctorate (Ph.D.) in Medicinal Chemistry from the University of Iowa, Iowa City, IA. Dr. Gangjee also holds a BS and MS in Organic Chemistry from the Indian Institute of Technology, Kharagpur, India. Dr. Gangjee is a Distinguished Professor of Medicinal Chemistry at Duquesne University. He has published more than 165 scientific publications and holds 37 patents.

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Dequesne University
Pittsburgh, PA
USA

Peter G. Goekjian
Université Claude Bernard
Villeurbanne
France

Isabel Gomez-Monterrey (Biography
Isabel Gomez-Monterrey

Isabel M. Gomez-Monterrey is Associate Professor in the University “Federico II” of Naples with more of 25 years of experience in the academic research. She holds a Ph.D. in Chemistry from the University of Extremadura, Spain, and served as postdoctoral researcher at both the University René Descartes of Paris, and the Institute of Medicinal Chemistry (C.S.I.C.) of Madrid. She has published more than 85 scientific publications and one patent. Dr. Gomez-Monterrey is also faculty member of the Biotechnology Center at Naples, where she teaches “Principles of Medicinal Chemistry” for health biotechnology students.

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Department of Pharmacy, University of Naples
Naples
Italy

Andreas Hilgeroth
Martin-Luther University
Halle
Germany

Hsu-Shan Huang (Biography
Hsu-Shan Huang

Dr. Huang obtained a doctorate (Dr. rer. nat.) in Pharmacy (Medicinal Chemistry) from the University of Regensburg, Germany. Dr. Huang was former dean of School of Pharmacy, and head of the Department of Research and Development in NDMC and director of Department of Pharmacy Practice, Tri-Service General Hospital/NDMC. Currently, Dr. Huang is a Professor in College of Medical Science and Technology, Taipei Medical University also an Adjunct Professor in NDMC. He has published more than 90 scientific publications and is a named inventor of 30 issued U.S., Taiwan or other countries patents. Dr. Huang is currently the Editorial Advisory Board of this journal, published by Bentham Science Publishers.

Biography
S. Huang

Dr. Shile Huang focuses on studying the role of mTOR signaling in tumorigenesis and metastasis. Since 2008, he has been studying how mTOR regulates cell survival, cell motility and lymphangiogenesis; how some small molecules (e.g. curcumin, cryptotanshinone, dihydroartimisinin, and ciclopirox) act as anticancer agents and how the heavy metal cadmium induces neuronal apoptosis. He is an editor-in-chief for "Metals and Neurodegeneration". He serves as ad hoc reviewers for funding agencies (e.g. NIH, DOD, ACS, and AHA) and journals (e.g. Cancer research, Oncogene, JBC, etc.).

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Taipei Medical University
Taipei
Taiwan

Hiroto Izumi
University of Occupational and Environmental Health
Kitakyushu
Japan

Jinwoong Kim (Biography
Jinwoong Kim

Jinwoong Kim graduated College of Pharmacy, Seoul National University in 1979, and received master degree in science in the same College. Then he went to USA for doctoral studies at the University of Illinois at Chicago, graduating with a Ph.D. in Pharmacognosy in 1988. and moved to University of Oklahoma in Norman as postdoctoral fellow. He joined the College of Pharmacy, Seoul National University, his alma mater, in 1989, where he rose to the rank of Professor in 1999. He published about 140 papers in international journals, 10 books or book chapers, and 12 patents including 2 US Patent. He served Korean Society of Pharmacognosy as a President in 2009, and currently works as editorial advisory board members in the international scientific journals such as Planta Medica, Journal of Ethnopharmacology, and Drugs of the Future.

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Seoul National University
Seoul
Korea

Gregory Kouraklis (Biography
Gregory Kouraklis

Dr. Gregory Kouraklis obtained an M.D. from the University of Athens, Greece. He had postgraduate education in Greece and USA and he hold the specialty of General Surgery, with special interest in Surgical Oncology. His current position is Chairman of Surgery in the School of Medicine at the National and Kapodistrian University of Athens, Greece.

He has published more than 225 scientific publications in peer reviewed international journals, plus 150 in National journals.

Dr. Kouraklis is Editor in 2 books, Guest Editor in 3 special issues of Eur Surg Res, Senior Editor in 1 journal and Editorial Board in 20 journals.

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University of Athens
Athens
Greece

K. Lim (Biography
K. Lim

Dr. Kyu Lim is currently full Professor (1996- ), Department of Biochemistry, Chungnam National University School of Medicine, Korea. Dr. Lim is one of the leading scientists in the field of Omega-3 fatty acids and Cancer research. He has worked to identify novel molecular mechanisms of anticancer action of omega-3 fatty acids in several cancers since 2005. For example, he found that omega-3 fatty acids inhibits wnt/beta-catenin signaling and Cox-2 (Cancer Res, 2008; Mol Cancer Ther, 2009), and induces cell death through autophagy (Autophagy, 2011; BioMed Res Intl, 2013). Additionall, DHA degrades HPV E6/E7 oncoprotein through Ubiquitin/proteasome activation. Recently, he published that DHA suppresses breast cancer cell metastasis by targeting matrix-metalloproteinases (Oncotarget, 2016). He also published several books’ chapter and reviews on Omega-3 Fatty acids and Cancer. In 2010, he organized Korea-EU International Forum on Omega-3 fatty acids and Cancer. Dr. Lim has been invited to speak more than 50 times from International and domestic Laboratories.

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Chungnam National University
Daejeon
South Korea

Laurent Martiny (Biography
Laurent Martiny

Professor Laurent MARTINY has more than 25 years of experience in the research of molecular mechanisms involved in cancer progression. Laurent Martiny and his team aimed to elucidate the role of matrix macromolecules or peptides able to counteract or to facilitate invasiveness and tumoral dissemination in order to identify novel therapeutic targets or biomarkers leading to alternative therapeutic strategies. Notably, Pr Martiny and colleagues have published more than 65 manuscripts, 5 patents, 9 reviews . Pr. Martiny is also deputy director of UMR CNRS MEDyC (Extracellular Matrix and Cellular Dynamics) in Reims Champagne Ardenne University.

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University of Reims Champagne-Ardenne
Champagne-Ardenne
France

Siddavaram Nagini (Biography
Siddavaram Nagini

Dr. S. Nagini is currently a Professor in the Department of Biochemistry and Biotechnology, Annamalai University, Tamil Nadu, India. She did her Masters Degree in Biochemistry from JIPMER, Ph.D. in Cancer Institute, Chennai and postdoctoral research in the University of Liverpool, UK. Prof. Nagini's research focuses on oncogenic signalling pathways, molecular targets for chemointervention and comparative oncology. Prof. Nagini has supervised 16 Ph.D. students, and authored 4 books, 8 chapters in edited research volumes, and 135 international research papers. She has filed 1 national and 2 international patents. She has successfully completed several research projects and was the Coordinator for the Indian side of the Indo-EU Collaborative Project under the 7th Framework programme on FUNCFOOD. In 2002, she received the National Young Woman Bioscientist Award, from the Department of Biotechnology, Govt. of India.

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Annamalai University
Tamil Nadu
India

Neil Osheroff (Biography
Neil Osheroff

Neil Osheroff received a Bachelor’s Degree in Chemistry from Hobart College in 1974 followed by a Ph.D. in Biochemistry and Molecular Biology from Northwestern University in 1979. Dr. Osheroff moved to the Stanford University School of Medicine in 1980, where he was a Helen Hay Whitney Foundation postdoctoral fellow in the Department of Biochemistry. In 1983, he moved to the Vanderbilt University School of Medicine and he has been on the faculty since that time. Dr. Osheroff currently holds Professorships in the Departments of Biochemistry and Medicine and was endowed with the John G. Coniglio Chair in Biochemistry in 2003. Dr. Osheroff’s research focuses on DNA topoisomerases, essential enzymes that remove knots and tangles from the genome and are targets for several widely prescribed anticancer and antibacterial drugs.

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School of Medicine, Vanderbilt University
Nashville, TN
USA

Yves Pommier
National Institute of Health
Bethesda, MD
USA

Liang Qiao
The University of Sydney
Sydney
Australia

Diwan S. Rawat (Biography
Diwan S. Rawat

Professor Rawat obtained a doctorate (Ph.D.) in Chemistry from the Central Drug Research Institute, Lucknow, India under the supervision of Dr D Bhakuni. He has 18 years of experience in the field of medicinal chemistry aimed to treat cancer, microbial infections and Parkinson disease. Professor Rawat is a visiting Professor at Japan Advanced Institute of Science and Technology (JAIST), Japan.

Professor Rawat has authored more than 118 papers with 2750 citation with 32 H-index. He has nine patents to his credit and co-authored a book on “Bioactive marine natural products”. Professor Rawat is a member of Editorial Board of Anti-Cancer Agents in Medicinal Chemistry, Marine Drugs and he is an Associate Editor of RSC Advances.

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University of Delhi
Delhi
India

Paolo Ruzza
CNR - Institute of Biomolecular Chemistry
Padova
Italy

Manlio Tolomeo (Biography
Manlio Tolomeo

Dr. Manlio Tolomeo is a hematologist/oncologist and medical director of the Section of Infectious Diseases in Haematological and Oncological patients at the University Hospital of Palermo. He achieved his MD degree and Ph.D. in Hematology and Oncology at the University of Palermo. He is co-fonder and member of the executive board of a University Spin-off for the research and production of natural molecules for the treatment of cancer. Moreover, he is member of the scientific boards of the Interdipartimental Centre of Research in Clinical Oncology (University of Palermo) and the Authority on the Biological Risk in Agriculture (Sicilian Region Department of Agriculture). Dr. Tolomeo has authored more than 120 manuscripts and 3 patents.

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Universitá di Palermo
Palermo
Italy

Anne-Sophie Voisin-Chiret (Biography
Anne-Sophie Voisin-Chiret

Pharm.D. (2002); Ph.D. Caen (2005), University of Caen Normandie (France). Lecturer in Medicinal Chemistry (2007) in the School of Pharmacy at the University of Caen.

Since September 2015, she has assumed the position of Prof. of Medicinal Chemistry. Her research interests include medicinal chemistry in the field of protein-protein interactions, in order to design oligo(het)aromatic foldamers that mimic the ability of proteins to fold into well-defined conformations, such as helices and β-sheets. Since 2012 she has been leading a research program dedicated to the development of foldamers of interest in the treatment of ovarian cancers and neurodegenerative diseases.

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Université de Caen Basse Normandie
Caen cedex
France

J. Xiao (Biography
J. Xiao

Dr. Xiao obtained a doctorate (Ph.D.) in nutrition science from Okayama Prefectural University (Japan) in 2009 and worked as a Humboldtian in Universität Würzburg (Germany) supported by AvH Foundation. Currently Dr. Xiao is an Assistant Professor in University of Macau and a Distinguished Professor in Fujian Agriculture & Forestry University (China). He has published more than 120 scientific publications and is named a 2016 Highly Cited Researcher by Thomson Reuters. Dr. Xiao is currently the Editorial Board Member of Current Drug Metabolism, Frontiers in Pharmacology, Industrial Crops and Products, Phytochemical Analysis, Molecules, Journal of Berry Research, Phytomedicine, and Pharmacognosy Magazine.

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University of Macau
Taipa
Macau

C. Zhang (Biography
C. Zhang

Dr. Chao Zhang earned his Ph.D. degree in Polymer Chemistry (2005) from Wuhan University, China, and had been working as postdoctoral fellow at the University of Wisconsin-Milwaukee and the University of California, San Diego from 2006 to 2010. In 2010, Dr. Zhang joined the the School of Engineering at the Sun Yat-sen University (China) as an Associate Professor of Biomedical Engineering; he currently serves as the Associate Dean of the School and the head of the Biomedical Engineering Program. His current research interests include the nano-sized drug carriers, contrast agents for medical imaging, and tissue engineering.

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Sun Yat-Sen University
Guangzhou 510006
China


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