ISSN: 1875-6638 (Online)
ISSN: 1573-4064 (Print)


Volume 11, 8 Issues, 2015


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Medicinal Chemistry

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Editor-in-Chief:
Atta-ur-Rahman
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK
Email: mc@benthamscience.org

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Upcoming Articles (E-Pub Abstracts ahead of Print)

Hepatoprotective Effects of Polysaccharides from Selenium-Enriched Pyracantha fortuneana on Mice Liver Injury
Chengfu Yuan, Zhihong Li, Muhua Yi, Xiaoxing Wang, Fan Peng, Fangxiang Xiao, Tao Chen, Changdong Wang, Gohar Mushtaq and Mohammad Amjad Kamal
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Recent Updates on Peroxisome Proliferator-Activated Receptor δ Agonists for the Treatment of Metabolic Syndrome
Ajmer Singh Grewal, Meenu Beniwal, Deepti Pandita, Bhupinder Singh Sekhon and Viney Lather
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Design, Synthesis and QSAR Studies on a Series of 2, 5-Disubstituted-1,3,4-oxadiazole Derivatives of Diclofenac and Naproxen For Analgesic and Anti-inflammatory activity
K. Ilango, P. Valentina, Gajendra Kumar, Dushyant Dixit, Shrikant Nilewar and M. K Kathiravan
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New N, N,N’,N’-Tetradentate Pyrazoly Agents: Synthesis and Evaluation of their Antifungal and Antibacterial Activities
Farid Abrigach, Btissam Bouchal, Olivier Riant, Yohan Mace, Abdelilah Takfaoui, Smaail Radi, Abdelouahad Oussaid, Mohammed Bellaoui and Rachid Touzani
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Compounds Combining Aminoadamantane and Monoterpene Moieties: Cytotoxicity and Mutagenic Effects
Evgeniy V. Suslov, Konstantin Yu. Ponomarev, Artem D. Rogachev, Michail A. Pokrovsky, Andrey G. Pokrovsky, Maria B. Pykhtina, Anatoly B. Beklemishev, Dina V. Korchagina, Konstantin P. Volcho and Nariman F. Salakhutdinov
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a-Aminoisobutyric Acid Leads a Fluorescent Syn-Bimane Laser Probe Across the Blood-Brain Barrier
Inbal Lapidot, Danny Baranes, Albert Pinhasov, Gary Gellerman, Amnon Albeck, Flavio Grynszpan and Shimon E. Shatzmiller
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Thiosemicarbazone-Pt(II) Complex Causes a Growth Inhibitory Effect on Human Mesenchymal Stem Cells
J.P. Garcia-Ruiz, A.I. Matesanz, A. Perez and P. Souza
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Synthesis of Daumone Derivatives and their Antiangiogenic Activities on Chorioallantoic Membrane
Jeremy Ricci, Dongguk Min, Miyeon Oh, Hyenchong Lim, Won-Yoon Chung, Kwang-Kyun Park and Mankil Jung
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Molecular Design, Synthesis and Evaluation of 2,3-Diarylquinoxalines as Estrogen Receptor Ligands
Diego P. Sangi, Marcia R. Cominetti, Amanda B. Becceneri, Flavia A. Resende, Eliana A. Varanda, Carlos A. Montanari, Marcio W. Paixao and Arlene G. Correa
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Preparation and Biodistribution of Technetium-99m-Labeled Bis-Misonidazole (MISO) as an Imaging Agent for Tumour Hypoxia
Feng Wang, D i Fan, Jun Qian, Zhe Zhang, Jianhua Zhu and Jian Chen
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Exploring the Synthesis and Anticancer Potential of L-Tyrosine-Platinum(II) Hybrid Molecules
Caroline Descôteaux, Kevin Brasseur, Valérie Leblanc, Eric Asselin and Gervais Bérubé
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Design, Synthesis and Biological Evaluation of Palladium (II) Complexes with 1-(Substituted Benzyl) Azetidine-3,3-Dicarboxylates as Leaving Group
X u Gang, L u Hua, Jiang Zhitao, Shuying Zhang and Shaohua Gou
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Synthesis and Antibacterial Activity of Novel Quaternary Ammonium Pyridoxine Derivatives
Nikita V. Shtyrlin, Sergey V. Sapozhnikov, Sergey A. Koshkin, Alfiya G. Iksanova, Arthur H. Sabirov, Airat R. Kayumov, Aliya A. Nureeva, Marina I. Zeldi and Yurii G. Shtyrlin
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Regioselective Synthesis of 2-Chloroquinoline Based Ethyl 4-(3-Hydroxyphenyl)-2,7,7-Trimethyl-5-Oxo-1,4,5,6,7,8-Hexahydroquinoline-3-Carboxylates and their In-Silico Evaluation Against P. falciparum Lactate Dehydrogenase
K. Rajesh, P. Lavanya, P. Iniyavan, S. Sarveswari, Sudha Ramaiah, Anand Anbarasu and V. Vijayakumar
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Antimicrobial and Anti-Inflammatory Activities of Ppc-1, Active Principle of the Cellular Slime Mold Polysphondylium Pseudo-Candidum
Jabrane Azelmat, Serena Fiorito, Salvatore Genovese, Francesco Epifano and Daniel Grenier
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Roles of Natural Compounds from Medicinal Plants in Cancer Treatment: Structure and Mode of Action at Molecular Level
Mahmood Rasool, Arif Malik, Mahwish Arooj, Abdul Manan, Mahmood Husain Qazi, Mohammad Amjad Kamal, Ishfaq Ahmed Sheikh, Siew Hua Gan, Muhammad Asif and Muhammad Imran Naseer
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Synthesis and Anti-tumor Activities of Novel Phenyl Substituted Suberoylanilide Hydroxamic Acid Derivatives against Human Cancer Cells
Rui Xie, Jinghua Shi, Yue Qu, Pingwah Tang, Xinying Wu, Ming Yang and Qipeng Yuan
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Psychosis and Gestational Influenza: Meta-Analysis
Lei Cai, Chun-Lin Wan, Lin He, Simone de Jong and Kuo-Chen Chou
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Universality of Oxime K203 for Reactivation of Nerve Agent-Inhibited AChE
Kamil Kuca, Martina Hrabinova, Daniel Jun, Kamil Musilek, Marek Penhaker, Ondrej Krejcar and Ondrej Soukup
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Studies on Chemistry, Spectroscopy and Antioxidant Activities of Chromium(III)-Hydrazide Complexes
Bushra Shamshad, Rifat Ara Jamal, Uzma Ashiq, Mohammad Mahrooof-Tahir, Zara Shaikh, Sadaf Sultan and Khalid Mohammed Khan
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N-substituted pyrrole-based scaffolds as potential anticancer and antiviral lead structures
K. Pegklidou, N. Papastavro, P. Gkizis, D. Komiotis, J. Balzarini and I. Nicolaou
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Design, Synthesis of 6-Substituted-pyrido[3,2-d]pyridazine Derivatives with Anticonvulsant Activity
Dong Zheng-Qi, Xiao-Mei Liu, Cheng-Xi Wei and Zhe-Shan Quan
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Antioxidant Potentials and Xanthine Oxidase Inhibitory Effect of Two Furanocoumarins Isolated from Tamus communis L
Fatima Zerargui, Sabah Boumerfeg, Noureddine Charef, Abderrahmane Baghiani, Meriem Djarmouni, Seddik Khennouf, Lekhmici Arrar, Musa H. Abu Zarga and Mohammad S. Mubarak
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In Silico Screening for Identification of Novel Anti-Malarial Inhibitors by Molecular Docking, Pharmacophore Modeling and Virtual Screening
Sidra Batool, Zeshan Aslam Khan, Warda Kamal and Mohammad Amjad Kamal
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Recognition and Impact of Host-Derived Molecules on Bacterial Cell-to-Cell Signalling Pathways
Alina-Maria Holban, Mariana Carmen Chifiriuc and Veronica Lazar
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Synthesis and Evaluation of Anticancer Activity of 5-Ylidene-4-Aminothiazol-2(5H)-One Derivatives
Danylo Kaminskyy, Ivanna Subtel’na, Borys Zimenkovsky, Olexandr Karpenko, Andrzej Gzella and Roman Lesyk
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Synthesis and Biological Evaluation of Acetylenic Chalcones as Novel Anti-Inflammatory Agents
Chengguang Zhao, Jianpeng Feng, Mingming Zuo, Jianfeng Zhao, X u Shanmei, Suqing Zheng, Yali Zhang, Qinqin Tang, L u Zhongqiu, Guang Liang and Jianmin Zhou
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Inhibition of NF-kB Activation and Cytokines Production in THP-1 Monocytes by 2-Styrylchromones
Ana Gomes, João P. Capela, Daniela Ribeiro, Marisa Freitas, Artur M.S. Silva, Diana C.G.A. Pinto, Clementina M.M. Santos, José A.S. Cavaleiro, José L.F.C. Lima and Eduarda Fernandes
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Effects of Novel Alkyl Pyridine Platinum Complexes on Apoptosis in Ishikawa Endometrial Cancer Cells
Robert Czarnomysy, Anna Bielawska, Anna Muszyńska and Krzysztof Bielawski
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Chemometric Analysis of Some Biologically Active Groups of Drugs on the Basis Chromatographic and Molecular Modeling Data
Jolanta Stasiak, Marcin Koba, Tomasz Bączek and Adam Buciński
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Crystal Structures and Cytotoxicity of Ortho-Xylene Linked Bis-benzimidazolium Salts
Muhammad Adnan Iqbal, Rosenani A. Haque, Safaa A. Ahamed, Syedeh Fatimah Jafari, Mohamed B. Khadeer Ahamed and Amin M.S. Abdul Majid
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In Vitro and In Vivo Evaluation of 17-phenylpropylamine/phenoxyethylamine-17-demethoxygeldanamycins as Potent Hsp90 Inhibitors
L i Zhenyu, Lejiao Jia, X u Hongjiao, L u Chunhua and Yuemao Shen
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Cholinesterases Inhibitory Activities of N-Phenylthiazol-2-Amine Derivatives and their Molecular Docking Studies
Jamshed Iqbal, Mariya -al- Rashida, Ayesha Babar, Abdul Hameed, Muhammad Siraj Khan, Munawar Ali Munawar and Ather Farooq Khan
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Monoamine Oxidase Inhibition and Molecular Modeling Studies of Piperidyl-thienyl and 2-Pyrazoline Derivatives of Chalcones
Sumera Zaib, Syed Umar Farooq Rizvi, Sana Aslam, Matloob Ahmad, Mariya al-Rashid and Jamshed Iqbal
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Synthesis and In-Vitro Cytotoxicity of (E)-N,2,3-Triarylacrylamide Derivatives as Analogs of Combretastatin A-4
Kun-Ming Jiang, Xiao-Li Dai, Ke Li, Di Wu, Ji-Hong hang, Yi Jin and Jun Lin
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Investigation of the N-BP Binding at FPPS by Combined Computational Approaches
Azzurra Stefanucci, Alessandro Marrone and Mariangela Agamennone
View Abstract
Quinolinyl-Thienyl Chalcones as Monoamine Oxidase Inhibitors and their In Silico Modeling Studies
Sumera Zaib, Syed Umar Farooq Rizvi, Sana Aslam, Matloob Ahmad, Syed Mobasher Ali Abid, Mariya al-Rashida and Jamshed Iqbal
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Association of EGF rs4444903 and XPD rs13181 Polymorphisms with Cutaneous Melanoma in Caucasians
Jun Liu, Jia Song, Mei-Yan Wang, Lei Cai and Kuo-Chen Chou
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Anti-Cancer Activity of 2,4-Disubstituted Thiophene Derivatives: Dual Inhibitors of Lipoxygenase and Cyclooxygenase
Rakesh K Sathya, Jagadish Swamy, Swaroop T Ramesh, Mohan C Dhananjaya, Ashwini Nanjundaswamy, Harsha K Bhadraiah, Farhan Zameer, Girish K Subbaiah and Rangappa K Subbegowda
View Abstract
Diagnostic Recognition of Escherichia coli Septicemia in In-Vivo Vascular Blood
Dal Woong Choi and Suw Young Ly
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Synthesis, in Vitro Biological Screening and Molecular Docking Studies of Novel Camphor Based Thiazoles
Krzysztof Z. Łączkowski, Konrad Misiura, Anna Biernasiuk, Anna Malm, Agata Siwek, Tomasz Plech, Emilia Ciok-Pater, Krzysztof Skowron and Eugenia Gospodarek
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