ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)


Volume 20, 42 Issues, 2014


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Current Pharmaceutical Design

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  • 62nd of 254 in Pharmacology & Pharmacy

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Editor-in-Chief:
William A. Banks
VAPSHCS/GRECC S-182
Building 1, Room 810A
1600 S. Columbian Way
Seattle, WA 98108
USA


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Current: 3.288
5 - Year: 3.555

Upcoming Articles (E-Pub Abstracts ahead of Print)

Clinical Applications of Choline PET/CT in Brain Tumors
Elisabetta Giovannini, Patrizia Lazzeri, Amelia Milano, Maria Chiara Gaeta and Andrea Ciarmiello
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PATHOPHYSIOLOGY OF IDIOPATHIC ATRIAL FIBRILLATION-PROGNOSTIC AND TREATMENT IMPLICATIONS
B Weijs, U Schotten and HJGM Crijns
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Best Practice for Atrial Fibrillation Patient Education
Deirdre A. Lane, Rachel V. Barker and Gregory Y. H. Lip
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Endothelial (Dys)Function in Lone Atrial Fibrillation
Marija M. Polovina, Gregory Y.H. Lip and Tatjana S. Potpara
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Asymptomatic Lone Atrial Fibrillation ­ How Can We Detect the Arrhythmia?
Giuseppe Boriani, Cinzia Valzania, Mauro Biffi, Igor Diemberger, Matteo Ziacchi and Cristian Martignani
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Mycobacterium w Immunotherapy for Treating Pulmonary Tuberculosis - a Systematic Review
Shaheen Pandie, Mark E. Engel, Zita S. Kerbelker and Bongani M. Mayosi
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The Case for Using Higher Doses of First Line Anti-Tuberculosis Drugs to Optimize Efficacy
Sylvain Goutelle, Laurent Bourguignon, Pascal Maire, Roger W. Jelliffe and Michael N. Neely
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Editorial Combined Cancer Therapy
Jasminka Pavelic
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Combined Modality Therapy in Pancreatic Adenocarcinoma: Review and Updates on a Controversial Issue
Ludimila Cavalcante, David P. Kelsen and Kenneth H. Yu
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Curcumin in Combined Cancer Therapy
Koraljka Gall Troselj and Renata Novak Kujundzic
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Mechanism-based Combinations with Pim Kinase Inhibitors in Cancer Treatments
Qingshan Yang, Lisa S. Chen and Varsha Gandhi
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Pancreatic Cancer: Systemic Combination Therapies for a Heterogeneous Disease
Davide Melisi, Lorenzo Calvetti, Melissa Frizziero and Giampaolo Tortora
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Pharmaco-therapeutic challenges in cancer biology with focus on the immune-system related risk factors
Zlatko Dembic
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A Comprehensive Review of Poorly Differentiated Neuroendocrine Carcinomas (pdNECs): a Niche to Find Novel Opportunities
Pablo Reguera, Ainhoa Madariaga and Enrique Grande
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Immunotoxins constructed with ribosome-inactivating proteins and their enhancers: a lethal cocktail with tumor specific efficacy
Roger Gilabert-Oriol, Alexander Weng, Benedicta von Mallinckrodt, Matthias F. Melzig, Hendrik Fuchs and Mayank Thakur
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Combined Cancer Therapy: Strategies to Overcome Acquired Aromatase Inhibitor Resistance
Susan B. Kesmodel, Gauri J. Sabnis, Saranya Chumsri and Angela MH Brodie
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NCRNA COMBINED THERAPY AS FUTURE TREATMENT OPTION FOR CANCER
Cornelia Braicu, Cristina Catana, George A. Calin and Ioana Berindan-Neagoe
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The Exploitation of Toll-like Receptor 3 Signaling in Cancer Therapy
Tanja Matijevic Glavan and Jasminka Pavelic
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Attacking c-Myc: Targeted and Combined Therapies for Cancer
Huilin Huang, Hengyou Weng, Hui Zhou and Lianghu Qu
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Oxidative Stress and Antioxidants in Carcinogenesis and Integrative Therapy of Cancer
Lidija Milkovic, Werner Siems, Renate Siems and Neven Zarkovic
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Anti-metastatics: an Overview of Drug Candidates in Current Pipelines
Anne Schaap-Nutt, Dane A. Thyssen, David W. Drell and Frank Entschladen
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Combining oncolytic virotherapy and cytotoxic therapies to fight cancer
Cristina Fillat, Maria Victoria Maliandi, Ana Mato-Berciano and Ramon Alemany
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Utility of Anti-Arrhythmic Medications in ‘Lone Atrial Fibrillation
Ramanan Kumareswaran and Paul Dorian
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Vitamin D3, D2 and Arterial Wall Properties in Coronary Artery Disease
Gerasimos Siasos, Dimitris Tousoulis, Evangelos Oikonomou, Konstantinos Maniatis, Stamatios Kioufis, Eleni Kokkou, Marina Zaromitidou, Eva Kassi, Antigoni Miliou, Christodoulos Stefanadis and Manolis Vavuranakis
View Abstract
CATHETER ABLATION OF LONE ATRIAL FIBRILLATION
Milan M. Marinković, Tatjana S. Potpara, László Gellér and Nebojša M. Mujović
View Abstract
Genetic Aspects of Lone Atrial Fibrillation: What Do We Know?
Laura Andreasen, Jonas B. Nielsen and Morten S. Olesen
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Lone atrial fibrillation- a diagnosis of exclusion
Antonio Tello-Montoliu, Diana Hernandez-Romero, Marianela Sanchez-Martinez, Mariano Valdes and Francisco Marin
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Biomarkers in Lone Atrial Fibrillation-An Additional ‘Fine Tuning’ of Risk?
Darae Ko, Jared Magnani and Elaine M. Hylek
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The Heart And Brain Imaging In Lone Atrial Fibrillation – Are We Surprised?
Karl Georg Haeusler, Jochen B. Fiebach, Günter Breithardt, Paulus Kirchhof and Eduard Shantsila
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Lone Atrial Fibrillation: Electrophysiology, Risk Factors, Catheter Ablation and Other Non-pharmacologic Treatments
Arun Kanmanthareddy, Martin P. Emert, Rhea C. Pimentel, Yeruva Madhu Reddy, Sudharani Bommana, Donita Atkins and Dhanunjaya Lakkireddy
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Editorial: Optimizing treatment in Rheumatoid Arthritis
Rosa P. Gomariz and Isidoro Gonzalez-Alvaro
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SPARC in Tumor Pathophysiology and as a Potential Therapeutic Target
Liling Tang and Jianguo Feng
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PET Radioligands for in Vivo Visualization of Neuroinflammation
Dieter Ory, Sofie Celen, Alfons Verbruggen and Guy Bormans
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Models And Methods In Cardiac Imaging For Metabolism Studies
M F Santarelli, N Martini, P Positano and L Landini
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Hyperpolarized Metabolic MR in the Study of Cardiac Function and Disease
M. H. Lauritzen, L. V. Sogaard, P. L. Madsen and J. H. Ardenkjaer-Larsen
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Cardiological Ultrasound Imaging
Johan M. Thijssen and Chris L. de Korte
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Imaging of Organ Metabolism in Obesity and Diabetes: Treatment Perspectives
J Hannukainen, MA Guzzardi, KA Virtanen, E Sanguinetti, P Nuutila and P Iozzo
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Treating Arterial Stiffness in Young and Elderly Patients with the Metabolic Syndrome
Konstantinos Tziomalos, Vasilios G. Athyros and Asterios Karagiannis
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Modification of Lifestyle Factors are Needed to Improve the Metabolic Health of Patients with Cardiovascular Disease Risk
Linda Landini
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Activated Immune System and Inflammation in Healthy Ageing: Relevance for Tryptophan and Neopterin Metabolism
Lucile Capuron, Simon Geisler, Katharina Kurz, Friedrich Leblhuber, Barbara Sperner-Unterweger and Dietmar Fuchs
View Abstract
Pain and Obesity in the Older Adult
Robert Taylor, Joseph V. Pergolizzi, Robert B. Raffa, Srinivas Nalamachu and Philip J. Balestrieri
View Abstract
Beyond Acetylcholinesterase Inhibitors for Treating Alzheimer's Disease: 7-nAChR Agonists in Human Clinical Trials
Patrizia Russo, Alessandra Del Bufalo, Alessandra Frustaci, Massimo Fini and Alfredo Cesario
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Use of Trastuzumab for Breast Cancer: the Role of Age
Walter Mazzucco, Marta Rossi, Rosanna Cusimano, Matteo Franchi, Martina Bonifazi, Alessandro Mistretta, Francesco Vitale, Walter Ricciardi, Eva Negri, Stefania Boccia and Carlo La Vecchia
View Abstract
Determinants of Longevity: Genetics, Biomarkers and Therapeutic Approaches
Juulia Jylhava
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MicroRNA Therapeutics in Neurological Disease
David S. Greenberg and Hermona Soreq
View Abstract
P4 Medicine Needs P4 Education
Alfredo Cesario, Charles Auffray, Patrizia Russo and Leroy Hood
View Abstract
Therapeutic Application of Intrabodies Against Age-Related Neurodegenerative Disorders
Alessio Cardinale, Daniela Merlo, Paolo Giunchedi and Silvia Biocca
View Abstract
Hyper-Longevity, a Late-Modern Paradigm for Understanding Longevity and Ageing in Western Developed Globalised Countries
Roberto Alzetta
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Editorial : Targeting vascular calcification: Up-date
Yuri V Bobryshev
View Abstract
Mechanisms of Medial Arterial Calcification in Diabetes
Dimitry A. Chistiakov, Igor A. Sobenin, Alexander N. Orekhov and Yuri V. Bobryshev
View Abstract
Mechanisms of Vascular Calcification and Associated Diseases
Juliana Marulanda, Saleh Alqarni and Monzur Murshed
View Abstract
New Therapeutic Approaches to Arterial Calcification Via Inhibition of Transglutaminase and B-Catenin Signaling
Mikhail Konoplyannikov and Maria Nurminskaya
View Abstract
Abdominal Aortic Calcification: Clinical Significance, Mechanisms and Therapies
Jonathan Golledge
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Vascular Calcification in Chronic Kidney Disease: Role of Disordered Mineral Metabolism
Shyamal Palit and Jessica Kendrick
View Abstract
Blood Serum Atherogenicity and Coronary Artery Calcification
Igor A. Sobenin, Veronica A. Myasoedova, Elena V. Anisimova, Xenia N. Pavlova, Stefan Möhlenkamp, Axel Schmermund, Rainer Seibel, Sina Berenbein, Nils Lehmann, Susanne Moebus, Jöckel Karl-Heinz, Alexander N. Orekhov and Raimund Erbel
View Abstract
Circulating Cellular Players in Vascular Calcification
Mattia Albiero, Angelo Avogaro and Gian Paolo Fadini
View Abstract
Editorial : Novel Insights into the Role of Anesthetics and Opioids in Organ or Tissue Protection
Hiroyuki Kinoshita
View Abstract
Mechanistic View of Renal Protective Action of Calcium Channel Blockade
N Sugano
View Abstract
Inhibitory Effects of Water Caltrop Pericarps on the Growth of Human Gastric Cancer Cells In Vitro
Qiusheng Lin, Junhui Shen, Ying Ning, Shengrong Shen and Undurti N. Das
View Abstract
Editorial: From gut inflammation to gastrointestinal disorders Current update on pathophysiology, molecular mechanism and pharmacological treatment modalities
Predrag Sikiric
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Manifestations In Course Of Celiac Disease: Case Report And Review Of The Literature
Skroza Nevena, Proietti Ilaria, Bernardini Nicoletta, La Viola Giorgio, Mancini Maria Teresa, Nicolucci Francesca, Pampena Riccardo, Tolino Ersilia, Zuber Sara and Potenza Concetta
View Abstract
Helicobacter pylori eradication therapy: advantages and disadvantages
Justyna Bien, Maria Bozko, Nisar P. Malek and Przemyslaw Bozko
View Abstract
EDITORIAL:The Multidomain Mobility Lab in Older Persons: From Bench to Bedside
Marcello Maggio, Gian Paolo Ceda and Fulvio Lauretani
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Role of brain NUCB2/nesfatin-1 in the regulation of food intake
Andreas Stengel and Yvette Taché
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Regulation of Gastric Nesfatin-1/NUCB2
Ziru Li, Michael Mulholland and Weizhen Zhang
View Abstract
Discovery of Nesfatin-1 and Overview of Biological Actions and New Developments
Masatomo Mori, Masanobu Yamada, Shuichi Okada, Koshi Hashimoto, Tesurou Satoh, Hiroyuki Shimizu and Toshihiko Yada
View Abstract
Role of NUCB2/nesfatin-1 in glucose control: diverse functions in islets, adipocytes and brain
Masanori Nakata and Toshihiko Yada
View Abstract
Central and peripheral expression and distribution of NUCB2/nesfatin-1
Miriam Goebel-Stengel and Lixin Wang
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Role of NUCB2/nesfatin–1 as a possible biomarker
Suleyman Aydin
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Editorial: Rational Design of Antiviral Compounds
Vladimir Frecer and Stanislav Miertus
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EDITORIAL Advances in Computational Structure Based Drug Discovery
Gergely Tóth
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Editorial Cardio-Metabolic Complications: Current Perspective and Future Developments.
Joseph Fomusi Ndisang
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EDITORAL Novel strategies for cardiac repair post-myocardial infarction
Simeon Agathopoulos and Theofilos M. Kolettis
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EDITORIAL: NEUROBIOLOGICAL AND NEUROCOGNITIVE BASIS OF THE EFFECTS OF CANNABINOIDS IN ANIMALS AND MAN: THERAPEUTIC POTENTIAL OF CANNABINOIDS IN PSYCHIATRY
Sagnik Bhattacharyya
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Dietary Interventions for Atopic Disorders
Despoina Mavrommati and Theoharis C. Theoharides
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Editorial Leptin and the cardiovascular system – a target for therapeutic interventions
Jerzy Bełtowski
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EDITORIAL Structure-based Drug Design: Strategies and Challenges
Guang-Fu Yang
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