ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)


Volume 22, 46 Issues, 2016


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Current Pharmaceutical Design

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  • 73rd of 253 in Pharmacology & Pharmacy

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Editor-in-Chief:
William A. Banks
VAPSHCS/GRECC S-182
Building 1, Room 810A
1600 S. Columbian Way
Seattle, WA 98108
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Current: 3.052
5 - Year: 3.132

Upcoming Articles (E-Pub Abstracts ahead of Print)

Efficacy of Ropinirole-Loaded PLGA Microspheres For The Reversion Of Rotenone-Induced Parkinsonism


Sofía Negro, Liudmilla Boeva, Karla Slowing, Ana Fernández-Carballido, Luis García-García and Emilia Barcia.


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Calixarene: A versatile material for drug design and applications


Muhammad Ajaz Hussain, Muhammad Umer Ashraf, Gulzar Muhammad, Muhammad Nawaz Tahir and Syed Nasir Abbas Bukhari.


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The role of PPARs in pathological cardiac hypertrophy and heart failure


Hai-Han Liao, Xu-Hui Jia, Huang-Jun Liu, Yang Zheng and Tang Qizhu.


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Hypersensitivity Reactions to Non-Steroidal Anti-Inflammatory Drugs


Inmaculada Doña, María Salas, James R. Perkins, Esther Barrionuevo, Francesco Gaeta, Jose A. Cornejo-García, Paloma Campo and Maria José Torres.


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Severe drug hypersensitivity reactions: Clinical pattern, diagnosis, etiology and therapeutic options


Maren Paulmann and Maja Mockenhaupt.


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Mast Cell Disorders In Drug Hypersensitivity


Patrizia Bonadonna, Massimiliano Bonifacio and Roberta Zanotti.


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Adduct Formation and Context Factors in Drug Hypersensitivity: Insight from Proteomic Studies


Juan M. González-Morena, María I. Montañez, Giancarlo Aldini, Francisco J. Sánchez-Gómez and Dolores Pérez-Sala.


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Development of a novel human scFv against EGFR L2 domain by phage display technology


Leila Rahbarnia, Safar Farajnia, Hossein Babaei, Jafar Majidi, Kamal Veisi, Shiva Ahdi Khosroshahi and Asghar Tanomand.


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Genetic Predictors of Drug Hypersensitivity


José A. Cornejo-García, Abderrahim Oussalah, Miguel Blanca, Rosa-María Guéant-Rodríguez, Cristobalina Mayorga, Julie Waton, Annick Barbaud, Francesco Gaeta, Antonino Romano and Jean-Louis Guéant.


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Specific Aspects of Drug Hypersensitivity in Children


Bergmann Marcel M and Caubet Jean-Christoph.


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Predictive Modeling of Ocular Pharmacokinetics and Adverse Effects


Leo Ghemtio, Henri Xhaard, Arto Urtti and Heidi Kidron.


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Polypharmacology in Precision Oncology: Current Applications and Future Prospects


Albert A. Antolin, Paul Workman, Jordi Mestres and Bissan Al-Lazikani.


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Identification of Useful Nanobodies by Phage Display of Immune Single Domain Libraries Derived from Camelid Heavy Chain Antibodies


Ema Romão, Francisco Morales-Yánez, Yaozhong Hu, Maxine Crauwels, Pieter De Pauw, Gholamreza Ghassanzadeh Hassanzadeh, Nick Devoogdt, Chloé Ackaert, Cécile Vincke and Serge Muyldermans.


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Therapeutic Antibodies by Phage Display


Hyunbo Shim.


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Unraveling Antibody Display: Systems Biology and Personalized Medicine


Luiz Ricardo Goulart, Paula Souza Santos, Ana Paula Carneiro, Barbara Brasil Santana, Antonio C. R. Valinotto and Thaise Gonçalves Araújo.


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Immunized Antibody Libraries: Manipulating The Diverse Immune Repertoire For Antibody Discovery


Theam Soon Lim and Soo Khim Chan.


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Engineered autonomous human variable domains


Johan Nilvebrant, Peter M. Tessier and Sachdev S Sidhu.


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New Advances in the Study of IgE Drug Recognition


Ángela Martín-Serrano, Nekane Barbero, José A. Agundez, Yolanda Vida, Ezequiel Pérez-Inestrosa and María I Montañez.


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Pleiotropic effects of simvastatin on some calcium regulatory and myofibrillar proteins in ischemic/reperfused heart: causality of statins cardioprotection?


Adrian Szobi, Martin Lichy, Slavka Carnicka, Dezider Pancza, Pavel Svec, Tana Ravingerova and Adriana Adameova.


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In silico systems pharmacology to assess drug's therapeutic and toxic effects


Alejandro Aguayo Orozco, Karine Audouze, Søren Brunak and Olivier Taboureau.


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Phage Display Derived IgNAR V Region Binding Domains for Therapeutic Development


Obinna C. Ubah, Caroline J. Barelle, Magdalena J. Buschhaus and Andrew J Porter.


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Organotin(IV) carboxylates as a promising potential drug candidates in the field of cancer chemotherapy


Muhammad Sirajuddin and Saqib Ali.


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From PK/PD to QSP: Understanding the Dynamic Effect of Cholesterol-Lowering Drugs on Atherosclerosis Progression and Stratified Medicine


Cesar Pichardo-Almarza and Vanessa Diaz-Zuccarini.


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Methods for Elucidation of DNA-Anticancer Drug Interactions and Their Applications in the Development of New Drugs


Majus Misiak, Francesco Mantegazza and Giovanni L Beretta.


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Genotype- or phenotype-targeting anticancer therapies? Lessons from tumor evolutionary biology


Alexandre E. Escargueil, Soizic Prado, Ambre Dezaire, Jean Clairambault, Annette K. Larsen and Daniele G Soares.


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Modeling Polypharmacological Profiles by Affinity Fingerprinting


Ágnes Peragovics, Zoltán Simon, András Málnási-Csizmadia and Andreas Bender.


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Cisplatin Analogues with an Increased Interaction with DNA: Prospects for Therapy


Megan E. Hardie, Hieronimus W. Kava and Vincent Murray.


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Emerging Role of G-quadruplex DNA as Target in Anticancer Therapy


Graziella Cimino-Reale, Nadia Zaffaroni and Marco Folini.


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Potential Role of Cardiovascular Imaging in Improving Cardiovascular Outcome in Coronary Artery Disease


Ines Valenta, Sahar Mirpour, Wael Marashdeh and Thomas H Schindler.


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Circulating microRNAs as novel potential diagnostic and prognosis biomarkers in pancreatic cancer


Safieh Ebrahimi, Faezeh Ghasemi, Seyed Mahdi Hassanian, Soodabeh Shahidsales, Ramin Mardani, Hamed Akbarzade, Seyed Mohammad Reza Parizadeh, Sharareh Gholamin, Anvar Soleimani, Majid Ghayour-Mobarhan and Amir Avan.


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Determing Effective Diabetic Care: A Multicentre - Longitudinal Interventional Study


Syed Wasif Gillani.


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A New Direction in Ophthalmic Development: Nanoparticle Drug Delivery Systems


Velichka Yordanova Andonova.


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Insulin-like growth factor-1, a potential predicative biomarker for postoperative delirium among elderly patients with open abdominal surgery


Huachun Shen, Yi Shao, Junping Chen and Jianrong Guo.


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Evaluation of the performance of an ophthalmic thermosensitive hydrogel containing combination of Suramin and Bevacizumab


Daniela Alejandra Quinteros, Emiliano Sebastián López, Juan Lucio Silva Couto, Belkys Angélica Maletto, Daniel Alberto Allemandi, Santiago Daniel Palma and Juan Eduardo Gallo.


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Solving the Blood-Brain Barrier Challenge for the Effective Treatment of HIV Replication in the Central Nervous System


Luc Bertrand, Madhavan Nair and Michal Toborek.


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Enkephalin-Fentanyl Multifunctional Opioids as Potential Neuroprotectants for Ischemic Stroke Treatment


Mohammad R. Islam, Li Yang, Yeon Sun Lee, Victor J. Hruby, Vardan T. Karamyan and Thomas J Abbruscato.


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Development of Novel miRNA-based Vaccines and Antivirals against Enterovirus 71


Isabel Yee Pinn Tsin and Poh Chit Laa.


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Polyphenol-Related Epigenetic Modifications in Osteoarthritis: Current Therapeutic Perspectives


Consuelo Arias, Tomás Zambrano, Dulcineia S.P. Abdalla and Luis A Salazar.


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The Influence of Tetracycline Inducible Targeting Rat PPARγ Gene Silencing on the Osteogenic and Adipogenic Differentiation of Bone Marrow Stromal Cells


Xiaobo Feng, Xianzhe Liu, Xianyi Cai, Tao Lin, Weihua Xu, Cao Yang, Yongwei Liu, Shuhua Yang and Dehao Fu.


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Gradually Expanding Scope for Biowaivers: An Overview


Vikrant Saluja, Amanpreet Singh and Adnan Mohammed Algradi.


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