ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)


Volume 23, 46 Issues, 2017


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Current Pharmaceutical Design

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  • 117th of 256 in Pharmacology & Pharmacy

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Upcoming Articles (E-Pub Abstracts ahead of Print)

Role and Therapeutic Potential of Astrocytes in Amyotrophic Lateral Sclerosis


Mariana Pehar, Benjamin A. Harlan, Kelby M. Killoy and Marcelo R Vargas.


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Method development in Forensic Toxicology


Frank T. Peters, Dirk K. Wissenbach, Francesco Paolo Busardò, Emilia Marchei and Simona Pichini.


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Targeting Astrocytes for Treating Neurological Disorders: Carbon Monoxide and Noradrenaline-Induced Increase in Lactate


Anemari Horvat, Nina Vardjan and Robert Zorec.


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Role of bradykinin in the regulation of endothelial nitric oxide synthase expression by cardiovascular drugs


Jin Bo Su.


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Post Mortem Redistribution of Drugs: Current State of Knowledge


Caroline Sastre, Christophe Bartoli, Valerie Baillif-Couniou, Georges Leonetti and Anne-Laure Pelissier-Alicot.


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Zein-based nanocarriers as potential natural alternatives for drug and gene delivery: Focus on cancer therapy


Ahmed Elzoghby, May Freag, Hadeer Mamdouh and Kadria Elkhodairy.


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Functional nanoparticles and their interactions with mesenchymal stem cells


Weiwei Wang, Zijun Deng, Xun Xu , Zhengdong Li, Friedrich Jung, Nan Ma and Andreas Lendlein.


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“Stress” is 80 years old: From Hans Selye original paper in 1936 to recent advances in GI ulceration


Sandor Szabo, Masashi Yoshida, Janos Filakovszky and Gyorgy Juhasz.


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Metallothionein is a potential therapeutic strategy for amyotrophic lateral sclerosis


Shin-ichi Ono.


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Recent advances on the role of microRNAs in both insulin resistance and cancer


Adele Vivacqua, Paola De Marco, Antonino Belfiore and Marcello Maggiolini.


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Role of Host Factors on the Regulation of Tat-Mediated HIV-1 Transcription


Guillaume Mousseau and Susana T Valente.


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GLT-1 upregulation as a potential therapeutic target for ischemic brain injury


Yu-Yan Hu, Li Li, Xiao-Hui Xian, Min Zhang, Xiao-Cai Sun, Shu-Qin Li, Xin Cui, Jie Qi and Wen-Bin Li.


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LSD detection and interpretation in hair


Camille Richeval, Delphine Allorge, X. Vanhoye and Jean-michel Gaulier.


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Overview Of Forensic Toxicology, Yesterday, Today And In The Future


Heesun Chung and Sanggil Choe.


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HIV-1 Transcription Inhibitors Increase the Synthesis of Viral Non-Coding RNA that Contribute to Latency


Yao A. Akpamagbo, Catherine DeMarino, Michelle L. Pleet, Angela Schwab, Myosotys Rodriguez, Robert A. Barclay, Gavin Sampey, Sergey Iordanskiy, Nazira El-Hage and Fatah Kashanchi.


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Interest of single hair analysis to document drug exposure: literature review and a case report involving zuclopenthixol


Nathalie Allibe, Pascal Kintz, Amandine Faure, François Paysant, Anne-Pascale Michard-Lenoir, Françoise Stanke-Labesque, Virginie Scolan and Hélène Eysseric-Guerin.


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Trimethylamine N-oxide (TMAO) as a new potential therapeutic target for insulin resistance and cancer


Jens Oellgaard, Signe Abitz Winther, Tobias Schmidt Hansen, Peter Rossing and Bernt Johan von Scholten.


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Application of alphaviral vectors for immunomodulation in cancer therapy


Anna Zajakina, Karina Spunde and Kenneth Lundstrom.


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Are Markers of Cardiac Dysfunction Useful in the Assessment of Cardiovascular Risk in Dialysis Patients


Beata Franczyk, Anna Gluba-Brzózka, Piotr Bartnicki, Maciej Banach and Jacek Rysz.


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Studying interactions of drugs with cell membrane nutrient transporters: new frontiers of proteoliposome nanotechnology.


Mariafrancesca Scalise, Michele Galluccio, Lorena Pochini, Lara Console, Maria Barile, Nicola Giangregorio, Annamaria Tonazzi and Cesare Indiveri.


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Using β-Amino Acids and β-Peptide Templates to Create Bioactive Ligands and Biomaterials


Mark P Del Borgo, Ketav Kulkarni and Marie-Isabel Aguilar.


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Current methods of the circulating tumor cells (CTC) analysis: a brief overview


Natalia Dementeva, Daria Kokova and Oleg A Mayboroda.


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Protein Tyrosine signaling and its potential therapeutic implications in carcinogenesis


Mihwa Kim, Minwoo Baek and Dae Joon Kim.


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Recent Advances in Targeting the HIV-1 Tat/TAR Complex


Fardokht A. Abulwerdi and Stuart FJ Le Grice.


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Chemokine like receptor- 1 (CMKLR-1) receptor: A Potential Therapeutic Target in Management of Chemerin Induced Type 2 Diabetes Mellitus and Cancer


Sangeetha Perumalsamy, Nurul Ain Aqilah Mohd Zin, Riyanto Teguh Widodo, Wan Azman Wan Ahmad, Shireene Ratna DB Vethakkan and Hasniza Zaman Huri.


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Membrane-bound ATP-dependent Energy Systems, as Extra- and Intracellular Key Signals for Gastrointestinal Functions and their Regulations in the Gastrointestinal Mucosa


Gyula Mózsik, Imre László Szabó and József Czimmer.


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Icariin Attenuates Interleukin-1β-Induced Inflammatory Response in Human Nucleus Pulposus Cells


Wen-bin Hua, Yu-kun Zhang, Xing-huo Wu, Liang Kang, Ji Tu, Kang-cheng Zhao, Shuai Li, Kun Wang, Yu Song, Rong-jin Luo, Zeng-wu Shao and Cao Yang.


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Albumin nanocarriers, γ - irradiated crosslinked, combined with therapeutic drugs for cancer therapy


Macarena Siri, Estefanía Achilli, Mariano Grasselli and Silvia del V Alonso.


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Protein Kinase Inhibitors as Potential Antimicrobial Drugs against Tuberculosis, Malaria and HIV


Yong Cheng, Jeffrey S. Schorey, Cheng-Cai Zhang and Xuejuan Tan.


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Management of blood pressure and heart rate in patients with diabetes mellitus


Ioanna Gouni-Berthold, Ruth Hanssen, Lisa Ravarani and Heiner K Berthold.


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Tumor reversion: mesenchymal-epithelial transition as a critical step in managing the tumor-microenvironment cross-talk


Mariano Bizzarri, Alessandra Cucina and Sara Proietti.


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Sialidases: Therapeutic and Antiatherogenic Potential


Vasily Nikolaevich Sukhorukov , Vasily Petrovich Karagodin , Emile Rustemovich Zakiev , Andrey Vyacheslavovich Grechko and Alexandr Nikolaevich Orekhov.


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Tumor Targeting of Polymeric Nanoparticles Conjugated with Peptides, Saccharides, and Small Molecules for Anticancer Drugs


Banu Bayram, Aykut Özgür, Lütfi Tutar and Yusuf Tutar.


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Why Not All Hypertensive Patients Are Tachycardic at Rest?


Maciej Siński, Piotr Jędrusik and Jacek Lewandowski.


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What Is The Real Efficacy Of Beta-Blockers For The Treatment Of Essential Hypertension?


Christian Höcht, Facundo M Bertera, Julieta S Del Mauro, Yanina Santander Plantamura, Carlos A Taira and Ariel H Polizio.


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Role of Protein Kinases and Their Inhibitors in Radiation Response of Tumor Cells


Byeong Mo Kim, Wonsuck Yoon, Jung-Hyun Shim, Haiyoung Jung, Ji Hong Lim, Hyun-Jung Choi, MiRan Seo, Tae Ho Lee and Sang-Hyun Min.


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How to treat patients with essential hypertension and peripheral arterial disease.


Salvatore Santo Signorelli.


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Formulation, Quality Control and Safety Issues of Nanocarriers Used For Cancer Treatment


Ismael D. Bianco, Marcelo R. Ceballos, Cristian Casado, Viviana G. Dabbene, Carolina Rizzi and R Kiyomi Mizutamari.


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Anthocyanins: Possible role as Multitarget therapeutic agents for prevention and therapy of chronic diseases


Swathi Putta, Nagendra Sastry Yarla, Ilaria Peluso, Dinesh Kumar Tiwari, Gorla V.Reddy, Priyanka Voori Giri, Naresh Kumar, Ramarao Malla, Veera Brahma Chari, Rama Sekhara Reddy D, Ramesh Bade, Mastan Mannarapu, George Barretto, Da-Yong Lu, Vadim V. Tarasov, Vladimir N. Chubarev, Frederico Fávaro Ribeiro, Luciana Scotti, Marcus T. Scotti, M. A.Kamal, Gjumrakch Aliev, Chinthalapally V. Rao, George Perry and Anupam Bishayee.


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Synthesis and biological evaluation of new tyrosol-salicylate derivatives as potential anti-inflammatory agents


Rafael P. Aguiar, Fahad S. Aldawsari, Luiz A. M. Wiirzler, Saulo E. Silva- Filho, Francielli M. S. Silva-Comar, Ciomar A. Bersani-Amado, Carlos A. Velázquez-Martínez and Roberto K N Cuman.


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Tissue engineered skin and wound healing: current strategies and future directions


Nandana Bhardwaj, Dimple Chouhan and Biman B Mandal.


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Effect of magnesium supplementation on plasma C-reactive protein concentrations: A systematic review and meta-analysis of randomized controlled trials.


Luis E. Simental-Mendía, Amirhossein Sahebkar, Martha Rodríguez-Morán, Graciela Zambrano-Galván and Fernando Guerrero-Romero.


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The second-generation of highly potent hepatitis C virus (HCV) NS3/4A protease inhibitors: Evolutionary design based on tailor-made amino acids, synthesis and major features of bio-activity


Shuni Wang, Yibing Wang, Jiang Wang, Tatsunori Sato, Kunisuke Izawa, Vadim A. Soloshonok and Hong Liu.


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Using properties of tumor microenvironments for controlling local, on-demand delivery from biopolymer-based nanocarriers.


Abdullah K. Alshememry, Suleiman S. El-Tokhy and Larry D Unsworth.


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Effects of oral and non-insulin injectable antidiabetic treatment in hypertension: a systematic review


Vasiliki Katsi, Georgios Georgiopoulos, Georgia Vogiatzi, Dimitrios Oikonomou, Maria Megapanou, John Skoumas, Charalampos Vlachopoulos, Petros Nihoyannopoulos and Dimitris Tousoulis.


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Pivotal roles of Interleukin-17 as the Epicenter of Bone Loss Diseases


Chongshan Liao, Chengfei Zhang and Yanqi Yang.


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Hybrid polymeric-magnetic nanoparticles in cancer treatments


Alexandra Muñoz Bonilla and Pilar Herrasti González.


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Nanovesicular formulations for cancer gene therapy


Lorena Tavano, Elisabetta Mazzotta and Rita Muzzalupo.


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Engineered Bone Tissue with Naturally-Derived Small Molecules


Guleid Awale, Edgar Wong, Komal Rajpura and Kevin W-H Lo.


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From tendon injury to collagen-based tendon regeneration: overview and recent advances


Clément Rieu, Lise Picaut, Gervaise Mosser and Léa Trichet.


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Long-lasting insulin treatment via a single subcutaneous administration of liposomes in thermoreversible Pluronic® F127 based hydrogel


Xiaoyu Chen, Blenda Chi Kwan Wong, Hubiao Chen, Shiping Zhang, Zhaoxiang Bian, Ge Zhang, Congcong Lin, Muhammad Kashif Riaz, Deependra Tyagi, Aiping Lu and Zhijun Yang.


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Anti-cancer drug delivery using carbohydrate-based polymers


Javad Ranjbari, Ahad Mokhtarzadeh, Abbas Alibakhshi, Maryam Tabarzad, Maryam Hejazi and Mohammad Ramezani.


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Hormones and Sarcopenia


John E Morley.


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miR-126 as a therapeutic agent for Diabetes Mellitus


Elham Pishavar and Javad Behravan.


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Percutaneous treatment of aortic valve disease: contemporary overview and future trends


Marko Banovic, Jozef Bartunek, Serge D. Nikolic, Vladan Vukcevic, Srdjan Aleksandric and Bernard Iung.


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The role of exosomes and exosome-derived microRNAs in atherosclerosis


Xinjie Lu.


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Therapeutic potential of heme oxygenase-1/carbon monoxide system against ischemia-reperfusion injury


Yuanyuan Cheng and Jianhui Rong.


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Approaches of the transcriptomic analysis in astrocytes: Potential pharmacological targets


George E. Barreto , Rosa M. Gómez, Rosa Helena Bustos, Diego A. Forero, Gjumrakch Aliev, Jerzy Leszek, Valentina Echeverria and Janneth Gonzalez.


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Effect of intranasal administration of galanin-like peptide (GALP) on body weight and hepatic lipids accumulation in mice with diet-induced obesity.


Satoshi Hirako, Nobuhiro Wada, Haruaki Kageyama, Fumiko Takenoya, Hyounju Kim, Yuzuru Iizuka, Akiyo Matsumoto, Mai Okabe and Seiji Shioda.


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Vitamins in Heart Failure: Friend or Enemy?


George Georgiopoulos, Christina Chrysohoou, Georgia Vogiatzi , Nikolaos Magkas, Ippokratis Bournelis, Sofia Bampali, Damien Gruson and Dimitris Tousoulis.


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Synthesis and characterization of a new benzo indole derivative with apoptotic activity against colon cancer cells


Fatemeh Hajiaghaalipou, Fadhil Lafta Faraj, Elham Bagheri, Hamid Khaledi, Hapipah Mohd Ali, Nazia Abdul Majid and Mahmood Ameen Abdulla.


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Diabetes-related neurological implications and pharmacogenomics


Rojas Carranza Camilo Andrés, Bustos Cruz Rosa Helena, Pino Pinzón Carmen Juliana , Ariza Marquez Yeimy Viviana, Gómez Bello Rosa Margarita and Cañadas Garre Marisa.


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Medicinal plants as protective strategies against Parkinson’s Disease


Natalia Areiza Mazo, Valentina Echeverria, Ricardo Cabezas, Marco Ávila-Rodriguez, Gjumrakch Aliev, Jerzy Leszek and George E Barreto.


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Implications of photophysical and physicochemical factors on successful application of photodynamic therapy


Shubhajit Paul, Paul Wan Sia Heng and Lai Wah Chan.


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Mur Ligase Inhibitors as Anti-bacterials: A Comprehensive Review


Jaiprakash N. Sangshetti, Suyog S. Joshi, Rajendra H. Patil and Devanand B Shinde.


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Adiponectin as a Potential Therapeutic Target for Prostate Cancer


Hanuma Kumar Karnati, Manas Kumar Panigrahi, Yazhou Li, David Tweedie and Nigel H Greig.


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Sulfated glycans in HIV infection and therapy


Vitor H. Pomin, Francisco F. Bezerra and Paulo AG Soares.


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Plasmodial Hsp40s: New Avenues for Antimalarial Drug Discovery


Michael O Daniyan and Gregory L Blatch.


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Vegetable Organosulfur Compounds and their Health Promoting Effects


Spyridon A. Petropoulos, Francesco Di Gioia and Georgia Ntatsi.


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Potential Application of 5-Aryl-Substituted 2-Amino- benzamide Type of HDAC1/2-Selective Inhibitors to Pharmaceuticals


Shinichi Uesato, Yoshiyuki Hirata and Tsutomu Sasaki.


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Optimal Pre-treatment for Acute Exposure to the Organophosphate Dicrotophos


Dietrich Ernst Lorke, Syed M. Nurulain, Mohamed Y. Hasan, Kamil Kuča and Georg A Petroianu.


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