ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)


Volume 22, 46 Issues, 2016


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Current Pharmaceutical Design

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  • 62nd of 254 in Pharmacology & Pharmacy

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Editor-in-Chief:
William A. Banks
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Current: 3.452
5 - Year: 3.504

Upcoming Articles (E-Pub Abstracts ahead of Print)

Type 2 Diabetes Mellitus and Alzheimer’s Disease: Bridging the Pathophysiology and Management


Fahmida Alam, Md. Asiful Islam, Teguh Haryo Sasongko and Siew Hua Gan.


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Antiphospholipid Antibody-Mediated Thrombotic Mechanisms in Antiphospholipid syndrome: Towards Pathophysiology-Based Treatment


Md. Asiful Islam, Fahmida Alam, Teguh Haryo Sasongko and Siew Hua Gan.


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Difluorinated curcumin: A promising curcumin analogue with improved anti-tumor activity and pharmacokinetic profile


Amir Abbas Momtazi and Amirhossein Sahebkar.


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DNA Methylation: An Epigenetic Insight into Type 2 Diabetes Mellitus


Fahmida Alam, Md. Asiful Islam, Siew Hua Gan, Mafauzy Mohamed and Teguh Haryo Sasongko.


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Role of Colloidal Drug Delivery Carriers in Taxane-mediated Chemotherapy: A Review


Pramod Kumar, Kaisar Raza, Lokesh Kaushik, Ruchi Malik, Shweta Arora and Om Prakash Katare.


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Metal Ions and Metal Complexes in Alzheimer’s Disease


Angelo Spinello, Riccardo Bonsignore, Giampaolo Barone, Bernhard K. Keppler and Alessio Terenzi.


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Psychosocial Risk Factors Related to Ischemic Heart Disease in Women


Tina Varghese, Salim S. Hayek, Nikoloz Shekiladze, William M. Schultz and Nanette K Wenger.


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The impact of small heat shock proteins (HspBs) in Alzheimer`s and other neurological diseases


Nikola Golenhofen and Britta Bartelt-Kirbach.


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Protein Amyloidogenesis Investigated by Small Angle Scattering


Caterina Ricci, Francesco Spinozzi, Paolo Mariani and Maria Grazia Ortore.


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Therapeutic approaches targeting pathological tau aggregates


Julia Gerson and Rakez Kayed.


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Non-Demented Individuals with Alzheimer’s Disease Neuropathology: Resistance to Cognitive Decline May Reveal New Treatment Strategies.


Olga Zolochevska and Giulio Taglialatela.


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AFM-Based Single Molecule Techniques: unraveling the Amyloid Pathogenic Species


Francesco Simone Ruggeri, Johnny Habchi, Andrea Cerreta and Giovanni Dietler.


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Heterocyclic scaffolds for the treatment of Alzheimer’s Disease


Annamaria Martorana, Valentina Giacalone, Riccardo Bonsignore, Andrea Pace, Carla Gentile, Ivana Pibiri, Silvestre Buscemi, Antonino Lauria and Antonio Palumbo Piccionello.


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Alzheimer’s Disease and Molecular Chaperones: Current Knowledge and the Future of Chaperonotherapy


Antonella Marino Gammazza, Celeste Caruso Bavisotto, Rosario Barone, Everly Conway de Macario and Alberto JL Macario.


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Gender Differences of Autonomic control of the Cardiovascular System


Naga Venkata Pothineni, Lily F. Shirazi and Jawahar L Mehta.


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Computational modeling and experimental facts of mixed self-assembly systems


Paula V. Messina, Jose Miguel Besada-Porto, Ramón Rial, Humberto González-Díaz and Juan M Ruso.


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Systems Medicine approaches to improving understanding, treatment, and clinical management of Neuroendocrine Prostate Cancer


Kamlesh K Yadav, Shameer Khader, Ben Readhead, Shalini S Yadav, Li Li, Andrew Kasarksis, Ashutosh K Tewari and Joel T Dudley.


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Identification of Small Molecule as a High Affinity β2 Agonist Irrespectively Targeting Wild and Mutated (Thr164Ile) β 2 Adrenergic Receptor in the Treatment of Bronchial Asthma


Srinivas Bandaru, Mallika Alvala, Jyothy Akka, Someshwar Rao Sagurthi, Anuraj Nayarisseri, Sanjeev Kumar Singh and Hema Prasad Mundluru.


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Models for Self-assembly of nanoscale systems with biomedical applications


Paula V. Messina, Ramon Rial and Juan M Ruso.


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Structure- and ligand-based approaches to evaluate aporphynic alkaloids from Annonaceae as multi-target agent against Leishmania donovani


Vitor Prates Lorenzo, Ana Silvia Suassuna Carneiro Lúcio, Luciana Scotti, Josean Fechine Tavares, José Maria Barbosa Filho, Tatjana Keesen de Souza Lima Clemente, Juliana da Câmara Rocha and Marcus Tullius Scotti.


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Cell cycle kinases in osteosarcoma: potential for therapeutic intervention


Li Cheng, Chongchong Wang and Juehua Jing.


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How the Protein Architecture of RNases III Influences their Substrate Specificity?


Guillermin Agüero-Chapin, Gisselle Pérez-Machado, Juan Collí Mull, Evys Ancede-Gallardo, Agostinho Antunes and Gustavo A de la Riva de la Riva.


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Current status of ethosomes and elastic liposomes in dermal and transdermal drug delivery


Kevin Ita.


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A Case Report of IgG4-related Syndrome and Literature Review


Antonino Tuttolomondo, Irene Simonetta, Domenico Di Raimondo, Roberta Conigliaro, Francesca Corpora, Valerio Vassallo and Antonio Pinto.


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Intestinal Barrier Dysfunction in Human Pathology and Aging


Marcel Cerqueira César Machado and Fabiano Pinheiro da Silva.


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STATINS IN STROKE PREVENTION: PRESENT AND FUTURE


Luis Castilla-Guerra, María del Carmen Fernandez-Moreno and Miguel Angel Colmenero- Camacho.


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Pathogenetic Pathways of Cardiorenal Syndrome and Their Possible Therapeutic Implications


Kenichi Matsushita.


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PREVENTIVE AND THERAPEUTIC ROLE OF MUSCLE CONTRACTION AGAINST CHRONIC DISEASES


Domenico Di Raimondo, Gaia Musiari, Giuseppe Miceli, Valentina Arnao and Antonio Pinto.


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Inflammation, endothelial dysfunction and arterial stiffness as therapeutic targets in cardiovascular medicine


Vittoriano Della Corte, Antonino Tuttolomondo, Rosaria Pecoraro and Antonio Pinto.


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Probing the Hypothesis of SAR Continuity Restoration by the Removal of Activity Cliffs Generators in QSAR


Maykel Cruz-Monteagudo, José L. Medina-Franco, Yunier Perera-Sardiña, Fernanda Borges, Eduardo Tejera, Cesar Paz-y-Miño, Yunierkis Pérez-Castillo, Aminael Sánchez-Rodríguez, Zuleidys Contreras-Posada and M Natália D S Cordeiro.


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The potential use of piglets as human pediatric surrogate for preclinical pharmacokinetic and pharmacodynamic drug testing


Elke Gasthuys, Tim Vandecasteele, Pauline De Bruyne, Johan Vande Walle, Patrick De Backer, Pieter Cornillie, Mathias Devreese and Siska Croubels.


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Circulating microRNAs in hepatocellular carcinoma: potential diagnostic and prognostic biomarkers


Hamid Reza Mirzaei, Amirhossein Sahebkar, Foad Yazdi, Hosein Salehi, Mohammad Hasan Jafari, Afshin Namdar, Ehsan Khabazian, Mahmoud Reza Jaafri and Hamed Mirzaei.


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ABC transporters in the development of multidrug resistance in cancer therapy


Angelika Długosz and Anna Janecka.


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Passive targeting of cyclophosphamide-loaded carbonate apatite nanoparticles to liver impedes breast tumor growth in a syngeneic model


S Tiash and EH Chowdhury.


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Targeting inflammatory bowel diseases by nanocarriers loaded with small and biopharmaceutical anti-inflammatory drugs


Ana Beloqui, Régis Coco and Véronique Préat.


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MicroRNA-208a Potentiates Angiotensin II-triggered Cardiac Myoblasts Apoptosis via Inhibiting Nemo-like kinase (NLK)


Ying Huang, Yang Yang, Yong He, Cheng Huang, Xiaoming Meng and Jun Li.


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Site-Specific Thiol-mediated PEGylation of Streptokinase Leads to Improved Properties with Clinical Potential


Pooja Sawhney, Shekhar Kumar, Neeraj Maheshwari, Sumeet Singh Guleria, Neelam Dhar, Radhika Kashyup and Girish Sahni.


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Biomimetic approach to stimulate osteogenesis on titanium implant surfaces using fibronectin derived oligopeptide


Young-Dan Cho, Sung-Jun Kim, Han-Sol Bae, Won-Joon Yoon, Kyung-Hwa Kim, Hyun-Mo Ryoo, Yang-Jo Seol, Yong-Moo Lee, In-Chul Rhyu and Young Ku.


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Aptamers to hemagglutinin: a novel tool for influenza virus recognition and neutralization


Elena Zavyalova and Alexey Kopylov.


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Αlpha-2 adrenergic and opioids receptors participation in mice gastroprotection of Abelmoschus esculentus lectin


Kátia A. Ribeiro, Hellíada V. Chaves, Samuel Mateus Pereira Filho, Isabela Ribeiro Pinto, Dina Andressa Martins Monteiro, Samuel Oliveira Matos, Tatiane Santi-Gadelha, Carlos Alberto de Almeida Gadelha, José Thalles Jocelino Gomes de Lacerda, Lissiana M. V. Aguiar, Karuza M. A. Pereira, Norma M. B. Benevides, Vicente de Paulo T. Pinto, Gerardo Cristino Filho, Mirna M. Bezerra and Antonio A R Silva.


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Current And Experimental Pharmacological Approaches In Neonatal Hypoxic-Ischemic Encephalopathy


Teresa Zalewska, Joanna Jaworska and Malgorzata Ziemka-Nalecz.


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