ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)


Volume 21, 38 Issues, 2014


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Current Medicinal Chemistry

Aims & ScopeAbstracted/Indexed in

Ranking and Category:
  • 5th of 59 in Chemistry & Medicinal
  • 41st of 261 in Pharmacology & Pharmacy
  • 80th of 290 in Biochemistry & Molecular Biology

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Editor-in-Chief:
Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK
Email: cmc@benthamscience.org

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Current: 4.07
5 - Year: 4.471

Upcoming Articles (E-Pub Abstracts ahead of Print)

Intracranial Aneurysms; in Need of Early Diagnostic and Treatment using Bio- and Nanotechnology
Shima Salmasi and Alexander Marcus Seifalian
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Intracranial Stents Past, Present and the Future Trend: Stents Made with Nano-particle or Nanocomposite Biomaterials
Junjie Zhao, Deepak Kalaskar, Yasmin Farhatnia, Xiaoxin Bai, Peter E. Bulter and Alexander M. Seifalian
View Abstract
Nose-to-Brain Drug Delivery by Nanoparticles in the Treatment of Neurological Disorders
Wei-Yi Ong, Shalini Suku Maran and Luca Costantino
View Abstract
Challenges in the Design of Clinically Useful Brain-Targeted Drug Nanocarriers
Luca Costantino, Diana Boraschi and Mike Eaton
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Nanomedicine and its Application in Treatment of Microglia-Mediated Neuroinflammation
Nimmi Baby, Radhika Patnala, Eng-Ang Ling and S. ThameemDheen
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Engineered nanomaterials and the Nervous System: An Update
Myrtill Simko and Mats-Olof Mattsson
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Nanotechnology and Alzheimer’s Disease: What Has Been Done and What to Do
B. Ruozi, D. Belletti, F. Pederzoli, P. Veratti, F. Forni, M. A. Vandelli and G. Tosi
View Abstract
Nanomedicine Based Nanoparticles for Neurological Disorders
Bhasker Sriramoju, Rupinder K. Kanwar and Jagat R. Kanwar
View Abstract
Accessing Targeted Nanoparticles to the Brain: The Vascular Route
Annette Burkhart, Mihnaz Azizi, Maj Schneider Thomsen, Louiza Bohn Thomsen and Torben Moos
View Abstract
General Aspects of Metal Toxicity
Henryk Kozlowski, Paulina Kolkowska, Joanna Watly, Karolina Krzywoszynska and Slawomir Potocki
View Abstract
Interaction of Chemokines with their Receptors – From initial Chemokine Binding to Receptor Activating Steps
Stefanie Thiele and Mette Marie Rosenkilde
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Nanoparticles in Melanoma
M. A. Berciano-Guerrero, A. Montesa-Pino, G. Castaneda-Penalvo, L. Munoz-Fernandez and J. Rodriguez-Flores
View Abstract
A Glimpse of Matrix Metalloproteinases in Diabetic Nephropathy
Xiaoxuan Xu, L i Xiao, Ping Xiao, Shikun Yang, Fuyou Liu, Yashpal Y Kanwar and Lin Sun
View Abstract
Effects of Tetrahydrohyperforin in Mouse Hippocampal Slices: Neuroprotection, Long-term Potentiation and TRPC Channels
Carla Montecinos-Oliva, Andreas Schüller, Jorge Parodi, Francisco Melo and Nibaldo C. Inestrosa
View Abstract
Perspectives on Tuberculosis Pathogenesis and Discovery of Anti-Tubercular Drugs
Fidele Ntie-Kang, Joseph N. Yong, Luc C Owono Owono, Wolfgang Sippl and Eugene Megnassan
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Computational Approaches for the Identification and Optimization of Src Family Kinases Inhibitors
Giulio Poli, Adriano Martinelli and Tiziano Tuccinardi
View Abstract
Iron Chelating Strategies in Systemic Metal Overload, Neurodegeneration and Cancer
Elzbieta Gumienna-Kontecka, Monika Pyrkosz-Bulska, Agnieszka Szebesczyk and Malgorzata Oledzka
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Hydrogen Sulfide and Endothelial Dysfunction: Relationship with Nitric Oxide
Zaid Altaany, Francesco Moccia, Luca Munaron, Daniele Mancardi and Rui Wang
View Abstract
Endothelial dysfunction: The link between homocysteine and hydrogen sulfide
Sathnur B Pushpakumar, Sourav Kundu and Utpal Sen
View Abstract
Endothelial Dysfunction in Metabolic Diseases: Role of Oxidation and Possible Therapeutic Employment of N Acetylcysteine
Andi Masha and Valentino Martina
View Abstract
Chelating Agents for the Sequestration of Mercury(II) and Monomethyl Mercury(II)
Francesco Crea, Concetta De Stefano, Claudia Foti, Demetrio Milea and Silvio Sammartano
View Abstract
GABA System as a Target for New Drugs
Paula Kowalczyk and Katarzyna Kulig
View Abstract
DNA Binding Mode of Transition Metal Complexes, a Relationship to Tumor Cell Toxicity
Muhammad Ashfaq, Tayyaba Najam, Syed Shoaib Ahmad Shah, Muhammad Mahboob Baniahmad, Salma Shaheen, Rukhsana Tabassum and Gildardo Rivera
View Abstract
Novel in Situ Activity Assays for the Quantitative Molecular Analysis of Neurodegenerative Processes in the Retina
P.A.R. Ekström, M. Ueffing, E. Zrenner and F Paquet-Durand
View Abstract
BoronicAcid-based Enzyme Inhibitors: A Review of Recent Progress
W u Zhongyu, Hao Fang and X u Wenfang
View Abstract
Salvianolic Acid B Inhibits Atherogenesis of Vascular Cells through Induction of Nrf2-Dependent Heme Oxygenase-1
Hyun Jung Lee, MiRan Seo and Eun Jig Lee
View Abstract
Oxidative Stress, Redox Signaling and Cancer Chemoresistance: Putting Together the Pieces of the Puzzle
Vanessa Jacob Victorino, Luciana Pizzatti, Pamela Michelletti and Carolina Panis
View Abstract
Novel Nor-Homo- and Spiro-Oxetan- Steroids Target the Human Androgen Receptor and Act as Antiandrogens
Marie Thiele, Sebastian Rabe, Wiebke Hessenkemper, Daniela Roell, Sophie Bartsch, Florian Kraft, Tsion E. Abraham, Adriaan B. Houtsmuller, Martin E. van Royen, Athanassios Giannis and Aria Baniahmad
View Abstract
Fetal Programming of the Human Brain: is there a Link with Insurgence of Neurodegenerative Disorders in Adulthood?
G Faa, M A. Marcialis, A Ravarino, M Piras, M C Pintus and V Fanos
View Abstract
Effects of Iron and Copper Overload on the Human Liver: an Ultrastructural Study
D Fanni, V Fanos, C Gerosa, M Piras, A Dessì, A Atzei, P Van Eyken, Y Gibo and G Faa
View Abstract
Potential Therapeutic Drugs and Methods for the Treatment of Amyotrophic Lateral Sclerosis
Gladys Yacila and Youssef Sari
View Abstract
Toxicity of Nanoparticles
Maria Antonietta Zoroddu, Serenella Medici, Alessia Ledda, Valeria Marina Nurchi, Joanna I. Lachowicz and Massimiliano Peana
View Abstract
Copper Chelators: Chemical Properties and Biomedical Applications
Matteo Tegoni, Daniela Valensin, Leonardo Toso and Maurizio Remelli
View Abstract
Cell To Cell Spreading Of Misfolded Proteins As A Therapeutic Target In Motor Neuron Disease
Livia Pasquali, Paola Lenzi, Francesca Biagioni, Gabriele Siciliano and Francesco Fornai
View Abstract
bHLHTranscription Factors Inhibitors For Cancer Therapy: General Features For InSilico Drug Design
Igor F. Tsigelny, Valentina L. Kouznetsova, Sandeep C. Pingle and Santosh Kesari
View Abstract
Targeting Platinum Resistant Disease in Ovarian Cancer
Stefanie L. Morgan, Jamie E. Medina, Matthew M. Taylor and Daniela M. Dinulescu
View Abstract
Mechanism of Cancer Drug Resistance and the Involvement of Noncoding RNAs
Hongping Xia and Kam M. Hui
View Abstract
Four Major Factors Regulate Phosphatidylinositol 3-Kinasesignaling Pathwayin Cancers Induced by Infection of Human Papillomaviruses
Wu Jianhong, Jiezhong Chen, Lifang Zhang, Paul P. Masci and Kong-Nan Zhao
View Abstract
HIF-1 Signaling in Drug Resistance to Chemotherapy
Noel A. Warfel and Wafik S. El-Deiry
View Abstract
IL-6 Activated JAK/STAT3 Pathway and Sensitivity to Hsp90 Inhibitors in Multiple Myeloma
Iryna Kolosenko, Dan Grandér and Katja Pokrovskaja Tamm
View Abstract
Targeting Drug-Resistant Prostate Cancer with Dual PI3K/MTOR Inhibition
Kai Dun Tang and Ling Ming-Tat
View Abstract
Nanostructured Biomaterials with Antimicrobial Properties
Yesim Muge Sahin, Mehmet Yetmez, Faik N. Oktar, O. Gunduz, Simeon Agathopoulos, Ecaterina Andronescu, Denisa Ficai, Maria Sonmez and Anton Ficai
View Abstract
Biomedical Applications of Synthetic, Biodegradable Polymers for the Development of Anti-Infective Strategies
Serban Bertesteanu, Mariana Carmen Chifiriuc, Alexandru Mihai Grumezescu, Ατηanasia G. Printza, Thill Marie-Paule, Valentina Grumezescu, Vlad Mihaela, Veronica Lazar and Raluca Grigore
View Abstract
New Molecular Strategies for Reducing Implantable Medical Devices Associated Infections
Alina Maria Holban, Monica Cartelle Gestal and Alexandru Mihai Grumezescu
View Abstract
Methods for Synthesizing the Macromolecular Components of Smart Nanosized Carriers for Controlled Drug Delivery
Paul Cătălin Balaure and Alexandru Mihai Grumezescu
View Abstract
Advances in Bio-Hybrid Nanostructures with Anti-Pathogenic Activity
Keng-Shiang Huang, Shu-Chen Chang, Chih-Hui Yang and Chih-Yu Wang
View Abstract
Antimicrobial Applications of Water-Dispersible Magnetic Nanoparticles in Biomedicine
Keng-Shiang Huang, Dar-Bin Shieh, Chen-Sheng Yeh, Ping-Ching Wu and Fong-Yu Cheng
View Abstract
Editorial: Prevention of Microbial Biofilms - the Contribution of Micro and Nanostructured Materials
Alexandru Mihai Grumezescu and Carmen Mariana Chifiriuc
View Abstract
Perinatal Heart Programming: Long-Term Consequences
A. Faa, R. Ambu, G. Faa and V. Fanos
View Abstract
Antihypertensive Therapy in Children: Differences in Medical Approach Between the United States and Europe
P. P. Bassareo, V. Bassareo, N. Iacovidou and G. Mercuro
View Abstract
Editorial: Cardiovascular Drug Therapy in Paediatric Age: from Metabolomics to Clinical Practice
P. P. Bassareo and V. Fanos
View Abstract
Tumor Antigen-Derived Peptides Delivery for Cancer Immunotherapy
Ma Wenxue
View Abstract
Interaction of Crotamine and Protamine, Small Cationic Peptides, With The Retinal Spreading Depression
EmptyYN="Y" Fernandes de Lima V M, P Spencer and W Hanke
View Abstract
Editorial: Current status and progress of radiopharmaceuticals for molecular imaging and targeted therapy
Junbo Zhang
View Abstract
On the Physiological Role of Cytosolic 5’-Nucleotidase II (Cn-II): Pathological and Therapeutical Implications
Maria Grazia Tozzi, Rossana Pesi and Simone Allegrini
View Abstract
The role of soluble 5`-nucleotidases in the conversion of nucleotide analogs. Metabolic and therapeutic aspects
Andrzej C Składanowski
View Abstract
The Enzymology of Cytosolic Pyrimidine 5’-Nucleotidases: Functional Analysis and Physiopathological Implications
Giulio Magni, Adolfo Amici and Giuseppe Orsomando
View Abstract
5'-Nucleotidases, Nucleosides and their Distribution in the Brain: Pathological and Therapeutic Implications
Zsolt Kovács, Árpád Dobolyi, Katalin A. Kékesi and Gábor Juhász
View Abstract
Therapeutic Perspectives for CN-II in Cancer
Lars Petter Jordheim
View Abstract
Enzymatic Properties and Physiological Roles of Cytosolic 5’-Nucleotidase II
Roichi Itoh
View Abstract
Is The Expression Of Deoxynucleoside Kinases And 5´-Nucleotidases In Animal Tissues Related To The Biological Effects Of Nucleoside Analogs?
Staffan Eriksson
View Abstract
Editorial “ Metabolic, pathological, and therapeutic perspectives intracellular 5’-nucleotidases”
Piero Luigi Ipata
View Abstract
Metal complexes of biologically active ligands as potential antioxidants
Irena Kostova, Stefan Balkansky and Stefan Balkansky
View Abstract
System models, assays, and endpoint parameters to evaluate anticancer compounds during preclinical screening
Juan Sebastian Yakisich
View Abstract
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