ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)


Volume 24, 42 Issues, 2017


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Current Medicinal Chemistry

This journal supports open access

Aims & ScopeAbstracted/Indexed in

Ranking and Category:
  • 10th of 59 in Chemistry & Medicinal
  • 63rd of 253 in Pharmacology & Pharmacy
  • 100th of 289 in Biochemistry & Molecular Biology

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Editor-in-Chief:
Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK


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Current: 3.249
5 - Year: 3.508

Abstracts Ahead of Print

Structure Properties and Mechanisms of Action of Naturally Originated Phenolic Acids and Their Derivatives against Human Viral Infections


Yi-Hang Wu , Bing-Yi Zhang , Li-Peng Qiu, Rong-Fa Guan, Zi-Hong Ye and Xiao-Ping Yu.


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Antimicrobial Peptides: A Promising Therapeutic Strategy in Tackling Antimicrobial Resistance


Ramya Nuti , Sridhar Goud , A Prasanth Saraswati , Ravi Alvala and Mallika Alvala.


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The Emerging Picture of CDK11: Genetic, Functional and Medicinal Aspects


Nikolas Ferreira dos Santos Paparidis and Fernanda Canduri.


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Structure-Based Approaches Targeting Parasite Cysteine Proteases


Rafael Pinto Vieira, Viviane Corrêa Santos and Rafaela Salgado Ferreira.


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Cannabis phenolics and their bioactivities


Federica Pollastro, Alberto Minassi and Luigia Grazia Fresu.


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Anti-inflammatory Natural Prenylated Phenolic Compounds - Potential Lead Substances


Viliam Brezáni, Karel Šmejkal, Jan Hošek and Veronika Tomášová.


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A nanotechnology based strategy to increase the efficiency of cancer diagnosis and therapy: Folate conjugated gold nanoparticles


Jaber Beik, Sara Khademi, Neda Attaran , Saeed Sarkar , Ali Shakeri-Zadeh , Habib Ghaznavi and Hossein Ghadiri.


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Orally Administrated Small Molecule Drugs with Intestine Targeted Profile: Recent Development and Prospects


Hua Cao, Kai Wang, Yang-Liang Ye and Jian-Hua Shen.


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Induced pluripotent stem cells as a model for therapy personalization of pediatric patients: disease modeling and drug adverse effects prevention


Elena Genova, Marco Pelin, Katsunori Sasaki, Yue Fengming, Gaetana Lanzi, Stefania Masneri, Alessandro Ventura, Gabriele Stocco and Giuliana Decorti.


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Immune checkpoint inhibitors: basics and challenges


Bin Li, Ho Lam Chan and Pingping Chen.


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Histone Deacetylase Inhibitors in Tumor Immunotherapy


Li-Ming Zhao and Jie-Huan Zhang.


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Adoptive immunotherapy for B-cell malignancies using CD19-targeted chimeric antigen receptor T-cells: A systematic review of efficacy and safety


Lu Hao, Tongtong Li, Lung-Ji Chang and Xiaochuan Chen.


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Cadmium, organ toxicity and therapeutic approaches. A review on brain, kidney and testis damage


Mariagrazia Rinaldi , Antonio Micali , Herbert Marini , Elena Bianca Adamo, Domenico Puzzolo, Antonina Pisani , Vincenzo Trichilo , Domenica Altavilla , Francesco Squadrito and Letteria Minutoli.


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Therapeutic potential of co-enzyme Q10 in retinal diseases


Xun Zhang , Ali Mohammad Tohari , Fabio Marcheggiani , Xinzhi Zhou, James Reilly, Luca Tiano and Xinhua Shu.


View Abstract


Sarcopenia, aging and prospective interventional strategies


Tyler B. Waltz, Elayne M. Fivenson , Marya Morevati , Chuanhao Li , Kevin G. Becker , Vilhelm A. Bohr and Evandro Fei Fang.


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Atrial Fibrillation: Biomarkers determining prognosis


Savas Mazaris, Gerasimos Siasos, Evangelos Oikonomou, Vicky Tsigkou, Manolis Vavuranakis, Eleni Kokkou, Marina Zaromitidou, Georgios-Angelos Papamikroulis, Athanasios G Papavassiliou, Spyridon Papaioannou, Nikolaos Papageorgiou, George Latsios, Christodoulos Stefanadis and Dimitris Tousoulis.


View Abstract


Inflammatory biomarkers in atrial fibrillation


Effimia Zacharia, Nikolaos Papageorgiou, Adam Ioannou, Gerasimos Siasos, Manolis Vavuranakis, George Latsios, Charalampos Vlachopoulos, Konstantinos Toutouzas, Spyridon Deftereos, Rui Providência and Dimitris Tousoulis.


View Abstract


Electrochemical Immunosensors for Disease Detection and Diagnosis


Oana Hosu, Giulia Selvolini, Cecilia Cristea and Giovanna Marrazza.


View Abstract


Tyrosinase electrochemical biosensors monitoring medicinally significant substances


Milan Sýs and Karel Vytřas.


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Allosteric Targeting of Aurora A Kinase Using Small Molecules: A Step Forward Towards Next Generation Medicines?


Resmi C Panicker, Anthony G. Coyne and Rajavel Srinivasan.


View Abstract


Visible Light Therapy: Molecular Mechanisms and Therapeutic Opportunities.


Zandra C. Félix Garza, Matthias Born, Peter A.J. Hilbers, Natal A. W. van Riel and Joerg Liebmann.


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Protozoan parasites glycosylphosphatidylinositol anchors: structures, functions and trends for drug discovery


Ana Luísa Malaco Morotti, Maristela Braga Martins-Teixeira and Ivone Carvalho.


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Post cardiovascular surgery atrial fibrillation. Biomarkers determining prognosis.


Olivia Manfrini, Edina Cenko, Beatrice Ricci and Raffaele Bugiardini.


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Potential triazole-based molecules for the treatment of neglected diseases


Susimaire Pedersoli Mantoani, Peterson de Andrade, Talita Perez Cantuaria Chierrito, Andreza Silva Figueredo and Ivone Carvalho.


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Induced Pluripotent Stem Cell Technology: A Paradigm Shift in Medical Science for Drug Screening and Disease Modeling


Meera Nair, Sardul Singh Sandhu and Anil Kumar Sharma.


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Tuftsin – Properties and Analogs


Agnieszka Siebert , Monika Gensicka-Kowalewska , Grzegorz Cholewiński and Krystyna Dzierzbicka.


View Abstract


Fumitremorgins and Relatives – from Tremorgenic Compounds to Valuable Anti-Cancer Drugs


Wolf-Rainer Abraham.


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Effects of Resveratrol and other Polyphenols on the most common Brain Age-Related Diseases


Fiorella Sarubbo, David Moranta, Victor Jose Asensio, Antonio Miralles and Susana Esteban.


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Advanced methods for analysis of testosterone


Livia Alexandra Gugoasa and Raluca Ioana Stefan-van Staden.


View Abstract


Molecular Docking and Drug Discovery in β-Adrenergic Receptors


Santiago Vilar, Eduardo Sobarzo-Sánchez, Lourdes Santana and Eugenio Uriarte.


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Apoptosis and anti-cancer drug discovery: the power of medicinal fungi and plants


Jack Ho Wong, Stephen Cho Wing Sze, Tzi Bun Ng, Randy Chi Fai Cheung, Chit Tam, Kalin Yanbo Zhang, Xiuli Dan, Yau Sang Chan, William Chi Shing Cho, Charlene Cheuk Wing Ng, Mary Miu Yee Waye, Weicheng Liang, Jinfang Zhang, Jie Yang, Xiuyun Ye, Juan Lin, Xiujuan Ye, Hexiang Wang, Fang Liu, David Wai Chan, Hextan Yuen Sheung Ngan, Ou Sha , Guohui Li, Ryan Tse , Tak Fu Tse and Helen Chan.


View Abstract


HEALTHY DIET AND REDUCTION OF CHRONIC DISEASE RISKS OF NIGHT SHIFT WORKERS


Giovanni M. Ferri, Domenica Cavone, Graziana Intranuovo and Linda Macinagrossa.


View Abstract


The battle for iron between humans and microbes


Peggy L Carver.


View Abstract


Biosensing Technologies for Therapeutic Drug Monitoring


Anna Meneghello, Stefano Tartaggia, Maria Domenica Alvau, Federico Polo and Giuseppe Toffoli.


View Abstract


Redox State in Atrial Fibrillation Pathogenesis and Relevant Therapeutic Approaches


Alexios S. Antonopoulos, Athina Goliopoulou, Evangelos Oikonomou, Sotiris Tsalamandris, Georgios-Angelos Papamikroulis, George Lazaros, Eleftherios Tsiamis, George Latsios, Stella Brili, Spyridon Papaioannou, Vasiliki Gennimata and Dimitris Tousoulis.


View Abstract


Transient production of recombinant pharmaceutical proteins in plants: evolution and perspectives


Lilya Kopertekh and Joachim Schiemann.


View Abstract


Melatonin as pleiotropic molecule with therapeutic potential for type 2 diabetes and cancer


Marzena Wojcik, Michal Krawczyk, Pawel Wojcik, Katarzyna Cypryk and Lucyna Alicja Wozniak.


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Potential anti-inflammatory effects of hesperidin from the genus Citrus


Silvia Tejada, Samuel Pinya , Miquel Martorell, Xavier Capó, Josep A. Tur, Antoni Pons and Antoni Sureda.


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miR-149 as a potential molecular target for cancer


Suet Hui Ow, Pei Jou Chua and Boon Huat BAY.


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NGS technologies as a turning point in rare disease research, diagnosis, and treatment


Ana Fernández-Marmiesse, Sofía Gouveia and María L Couce.


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Nitroisoxazolones Showing Diverse Chemical Behavior: A Useful Building Block for Polyfunctionalized Systems


Nagatoshi Nishiwaki.


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Macrophage migration inhibitory factor – a favorable marker in inflammatory diseases?


Johannes Hertelendy , Georg Reumuth , David Simons, Christian Stoppe , Bong-Sung Kim, Jan-Philipp Stromps, Paul C. Fuchs , Jürgen Bernhagen, Norbert Pallua and Gerrit Grieb.


View Abstract


The Prospective Role of MicroRNAs in Depression


Zhiying Hu, Yuting Jiang , Xue Huo , Yang Yang , Henry Davies , Benson O.A. Botchway and Marong Fang.


View Abstract


Chemistry in the Bioactivity of Chlorophylls: An Overview


Antonio Pérez-Gálvez , Isabel Viera and María Roca.


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Therapeutic Application of Natural Medicine Monomers in Cancer Treatment


Chen Zhong , Nathan R. Wall , Yuangang Zu and Guangchao Sui.


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Targeting the Prokineticin System to Control Chronic Pain and Inflammation


Lucia Negri and Daniela Maftei.


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Advances in the anticancer value of the ursolic acid through nanodelivery


Azadeh Manayi, Marjan Nikan, Navid Nobakht Haghighid and Mohammad Abdollahi.


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A review of recent advancements in anti-tubercular molecular hybrids


Parvesh Singh, Bukola Jaiyeola , Nagaraju Kerru, Oluwakemi Ebenezer and Ajay Bissessur.


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An Overview of New Possible Treatments of Alzheimer’s Disease, Based on Natural Products and Semi-Synthetic Compounds


Enrico Zanforlin, Giuseppe Zagotto and Giovanni Ribaud.


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Rational drug design of antineoplastic agents using 3D-QSAR, cheminformatic, and virtual screening approaches


Jelica Vucicevic, Katarina Nikolic and John B O Mitchell.


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The Role Of Oxidative Stress Modulators In Breast Cancer


Hande Gurer-Orhan, Elif Ince, Dilan Konyar, Luciano Saso and Sibel Suzen.


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Recent Advances on Cellulose-Based Nano-Drug Delivery Systems: Design of Prodrugs and Nanoparticles


Lin Dai and Chuanling Si.


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Metabolic Syndrome: Sex-Related Cardiovascular Risk and Therapeutic Approach


Francesca Santilli, Damiano D’Ardes, Maria Teresa Guagnano and Giovanni Davi.


View Abstract


Chronic wounds: Innovations in diagnostics and therapeutics


Marieke Haalboom.


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Tackling chronic pain and inflammation through the purinergic system


Giulia Magni, Daniele Riccio and Stefania Ceruti.


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The Influence of Obese Insulin-Resistance on the Outcome of the Ischemia/Reperfusion Insult to the Heart


Krekwit Shinlapawittayatorn, Siriporn C. Chattipakorn and Nipon Chattipakorn.


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Recent Advances in Superparamagnetic Iron Oxide Based Nanoprobes as Multifunctional Theranostic Agents for Breast Cancer Imaging and Therapy


Jianjun Zheng , Wenzhi Ren, Tianxiang Chen , Jin Yinhua, Aijing Li , Kun Yan , Yijiao Wu and Aiguo Wu.


View Abstract


Applications of cellulose-based materials in sustained drug delivery systems


Bo Sun, Min Zhang, Jing Shen, Zhibin He, Pedram Fatehi and Yonghao Ni.


View Abstract


Glomerular endothelium and its impact on glomerular filtration barrier in diabetes: Are the gaps still illusive?


Joseph Fomusi Ndisang.


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Modulators of Acetylcholinesterase Activity: from Alzheimer's Disease to Anti-cancer Drugs


Tamara Lazarević-Pašti , Andreja Leskovac, Tatjana Momić, Sandra Petrović and Vesna Vasić.


View Abstract


HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: SAR and lead optimization using CoMFA and CoMSIA studies (1995-2016)


Murugesan Vanangamudi, Vasanthanathan Poongavanam and Vigneshwaran Namasivayam.


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Advances in the prediction of protein aggregation propensity


Irantzu Pallarès and Salvador Ventura.


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Exploiting Cancer Metal Metabolism using Anti-Cancer Metal-Binding Agents


Angelica Merlot, Danuta Kalinowski, Zaklina Kovacevic, Patric Jansson, Sumit Sahni, Michael Huang, Darius Lane, Hiu Lok and Des Richardson.


View Abstract


The Panomics Approach in Neurodegenerative Disorders


Balazs Szatmari, Peter Balicza, Gyorgy Nemeth and Judit Mária Molnár.


View Abstract


Attenuation of diabetes-induced cardiac and subcellular defects by sulphur-containing amino acids


Paramjit Tappia, Adriana Adameova and Naranjan Dhalla.


View Abstract


The beneficial effects of sulfur-containing amino acids on cisplatin-induced cardiotoxicity and neurotoxicity in rodents


Gvozden Rosic, Jovana Joksimovic, Dragica Selakovic, Vladimir Jakovljevic, Vladimir Zivkovic, Ivan Srejovic, Marko Djuric and Dragan Djuric.


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Hemicellulose from Plant Biomass in Medical and Pharmaceutical Application: A Critical Review


Xinxin Liu, Qixuan Lin, Yuhuan Yan, Fenf Peng, Runcang Sung and Junli Ren.


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Review on anti-cancer activity in wild plants of the Middle East


Einav Mayzlish-Gati, Marcelo Fridlender, Rameshprabu Nallathambi, Gopinath Selvaraj, Stalin Nadarajan and Hinanit Koltai.


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Immune Modulation of Asian Folk Herbal Medicines and Related Chemical Components for Cancer Management


Manee Patanaponpibul and Qiao-Hong Chen.


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Physicochemical and pharmacological characterization of permanently charged opioids


Károly Mazák , Béla Noszál and Sándor Hosztafi.


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Clinical approach to diabetic Cardiomiopathy: a review of human studies


Roberto Tarquini , Laura Pala , Simona Brancati , Giulia Vannini, Salvatore De Cosmo , Gianluigi Mazzoccoli and Carlo Maria Rotella.


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Pharmacogenetic and pharmacokinetic dose individualization of the taxane chemotherapeutic drugs paclitaxel and docetaxel


Natália Bordin Andriguetti , Suziane Raymundo, Marina Venzon Antunes, Magda Susana Perasolo, Simone Gasparin Verza, Edna Sayuri Suyenaga and Rafael Linden.


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Bis-2-aminoimidazolines and Bisguanidines: Synthetic Approaches, Antiparasitic Activity and DNA Binding Properties


Christophe Dardonville and J Jonathan Nué Martínez.


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A psycho-behavioral perspective on modelling obsessive-compulsive disorder (OCD) in animals: The role of context


De Wet Wolmarans, Dan J. Stein and Brian H Harvey.


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VDAC1 as a player in mitochondria-mediated apoptosis and target for modulating apoptosis


Varda Shoshan-Barmatz, Yakov Krelin and Quan Chen.


View Abstract


Lipid oxidation products in the pathogenesis of inflammation-related gut diseases


Barbara Sottero, Daniela Rossin, Giuseppe Poli and Fiorella Biasi.


View Abstract


The Complexity of Omega-3 Fatty acids modulation of Signaling Pathways related to Pancreatic Cancer


Carolina Torres , Andrew M. Diaz , Daniel R. Principe and Paul J Grippo.


View Abstract


Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions


Valeria Pittala, Luca Vanella, Loredana Salerno, Giuseppe Romeo, Agostino Marrazzo, Claudia Di Giacomo and Valeria Sorrenti.


View Abstract


Biological roles of the eclectic Chromogranin-A-derived peptide Catestatin


Teresa Pasqua , Tommaso Angelone , Angela Spena and Maria Carmela Cerra.


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New Perspectives on Biomedical Applications of Iron Oxide Nanoparticles


Massimiliano Magro, Davide Baratella, Emanuela Bonaiuto, Jessica de Almeida Roger and Fabio Vianello.


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Mechanisms of action, resistance and toxicity of insecticides targeting GABA receptors


Steven D. Buckingham, Makoto Ihara, David B Sattelle and Kazuhiko Matsuda.


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Sulfur – Containing Amino Acids Homocysteine And Taurine In Seizures: Current State Of The Art


Dragan Hrncic, Aleksandra Rasic-Markovic, Duro Macut, Dusan Mladenovic, Veselinka Susic, Dragan Djuric and Olivera Stanojlovic.


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Anticancer Polyphenols from Cultured Plant Cells: Production and New Bioengineering Strategies


Victor Bulgakov, Yulia V. Vereshchagina and Galina N Veremeichik.


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Sulphur-containing amino acids: protective role against free radicals and heavy metals


Mirjana B. Čolović, Vesna M. Vasić, Dragan M. Djuric and Danijela Z Krstić.


View Abstract


Electrochemical Detectors in Liquid Chromatography: Recent Trends in Pharmaceutical and Biomedical Analysis


Jean-Michel Kauffmanna, Nurgul K. Bakirhan, Burcin Bozal-Palabiyik, Bengi Uslu, Rocio Rodriguez Gomez, Marie Vandeput and Sibel A Ozkan.


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Beneficial effects of N-acetylcysteine and N-mercaptopropionylglycine on ischemia reperfusion injury in the heart


Monika Bartekova, Miroslav Barancik, Kristina Ferenczyova and Narajan S Dhalla.


View Abstract


Pigment epithelium-derived factor: A novel therapeutic target for cardiometabolic diseases and related complications


Sho-ichi Yamagishi and Takanori Matsui.


View Abstract


EPC dysfunction and immune networks: translating opportunities for the clinical setting in personalized medicine


Javier Rodríguez-Carrio, Patricia López and Ana Suárez.


View Abstract


Nonsteroidal Anti-Inflammatory Drugs: Exploiting Bivalent COXIB/TP Antagonists for the Control of Cardiovascular Risk


Silvia Carnevali, Carola Buccellati , Chiara Bolego , Massimo Bertinaria , G. Enrico Rovati and Angelo Sala.


View Abstract


Cdc42 Signaling Pathway Inhibition as a Therapeutic Target in Ras-Related Cancers


Byron J. Aguilar, Huchen Zhou and Qun Lu.


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The evaluation and utilization of marine-derived bioactive compounds with anti-obesity effect


Qiu Jin , Huahua Yu and Pengcheng Li.


View Abstract


Recent advances of individual BODIPY and BODIPY-based functional materials in medical diagnostics and treatment


Yuriy S. Marfin , Alexey V. Solomonov, Alexander S. Timin and Evgeniy V Rumyantsev.


View Abstract


Interactions of VDAC with proteins involved in neurodegenerative aggregation: an opportunity for advancement on therapeutic molecules


Andrea Magrì and Angela Messina.


View Abstract


The role of dietary approach in irritable bowel syndrome


Piero Portincasa, Antony Lembo, Ornella De Bari, Domenica M. Di Palo, Anna Maggio, Ilaria Cataldo and Giuseppe Calamita.


View Abstract


Modulation of Aquaporins by dietary patterns and plant bioactive compounds


Ilaria Cataldo, Anna Maggio , Patrizia Gena, Ornella de bari, Grazia Tamma , Piero Portincasa and Giuseppe Calamita.


View Abstract


Nanostructures for pH-sensitive drug delivery and magnetic resonance contrast enhancement systems


Xiao Sun, Guilong Zhang and Zhengyan Wu.


View Abstract


Targeting Nrf2 in the Protection against Renal Disease


Melania Guerrero Hue, Víctor Farré-Alins , Alejandra Palomino Antolín , Esther Parada, Alfonso Rubio-Navarro, Jesús Egido , Javier Egea and Juan Antonio Moreno.


View Abstract


Exposing “bright” metals: promising advances in photoactivated anticancer transition metal complexes


Aleksandra Bjelosevic, Benjamin J. Pages, Lawson K. Spare, Krishant M. Deo, Dale L. Ang and Janice R Aldrich-Wright.


View Abstract


Back to the bench? MEK and ERK inhibitors for the treatment of KRAS mutant lung adenocarcinoma


Jens Köhler , Marco Catalano and Chiara Ambrogio.


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Anti-cancer compounds targeted to VDAC: potential and perspectives


Simona Reina and Vito De Pinto.


View Abstract


VDAC-targeted drugs affecting cytoprotection and mitochondrial physiology in cerebrovascular and cardiovascular diseases..


Andonis Karachitos, Joaquin Jordan and Hanna Kmita.


View Abstract


Cyclometalated complexes of platinum and gold with biological properties: state-of-the-art and future perspectives


Sophie Jürgens, Fritz E. Kühn and Angela Casini.


View Abstract


Multi-Target-Directed Ligands Affecting Serotonergic Neurotransmission for Alzheimer’s Disease Therapy: Advances in Chemical and Biological Research


Agnieszka Jankowska, Anna Wesołowska , Maciej Pawłowski and Grażyna Chłoń-Rzepa.


View Abstract


Microwave: An Important and Efficient Tool for the Synthesis of Biological potent Organic Compounds


Kamlesh Kumari, Vijay K. Vishvakarma, Prashant Singh, Rajan Patel and Ramesh Chandra.


View Abstract


Potential of sulphur-containing amino acids in the prevention of catecholamine-induced arrhythmias


Adriana Adameova , Paramjit S Tappia, Robert Hatala and Naranjan S Dhalla.


View Abstract


Insect peptides – perspectives in human diseases treatment


Szymon Chowański , Zbigniew Adamski, Jan Lubawy , Paweł Marciniak , Joanna Pacholska-Bogalska , Małgorzata Słocińska , Marta Spochacz, Monika Szymczak , Arkadiusz Urbański , Karolina Walkowiak-Nowicka and Grzegorz Rosiński.


View Abstract


Role of positron emission tomography for central nervous system involvement in systemic autoimmune diseases: status and perspectives


Daniele Mauro , Gaetano Barbagallo , Salvatore D’Angelo, Sannino Pasqualina, Saverio Naty , Caterina Bruno, Ignazio Olivieri , Rosa Daniela Grembiale and Francesco Ursini.


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Impact of diabetes on cardiac and vascular disease: Role of calcium signaling


Tarik Smani, Isabel Gallardo-Castillo, Javier Ávila-Médina, Manuel F. Jimenez-Navarro, Antonio Ordoñez and Abdelkrim Hmadcha.


View Abstract


Improving Metabolic Control Through Functional Foods


John G. Jones and Joao CP Silva.


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Nutrition as a Health Determinant in Elderly Patients


Ignazio Grattagliano and Tecla Mastronuzzi.


View Abstract


Natural Product Gossypol and Its Derivatives in Precision Cancer Medicine


Yun Zeng , Jingwen Ma , Liang Xu and Daocheng Wu.


View Abstract


Role of infrared spectroscopy and imaging in cancer diagnosis


Saroj Kumar , Alagiri Srinivasan and Fredrik Nikolajeff.


View Abstract


Piperine as a potential anti-cancer agent: a Review on Preclinical studies


Azadeh Manayi, Seyed Mohammad Nabavi, William N. Setzer and Samineh Jafari.


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Phenolic compounds from edible algae: bioactivity and health benefits


Lidia Montero , Andrea del Pilar Sánchez-Camargo, Elena Ibáñez and Bienvenida Gilbert-López.


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Targeting DNA minor groove by hybrid molecules as anticancer agents


Shalini Nekkanti , Ramya Tokala and Nagula Shankaraiah.


View Abstract


Modulators of the Efflux Pump Cdr1p of Candida albicans: Mechanisms of Action and Chemical Features


Viet-Khoa Tran-Nguyen, Rajendra Prasad, Pierre Falson and Ahcène Boumendjel.


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Effects of diets on adipose tissue


Silvia Ezquerro, Amaia Rodríguez, Piero Portincasa and Gema Frühbeck.


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Repurposing of Copper(II)-chelating drugs for the treatment of neurodegenerative diseases.


Valeria Lanza, Danilo Milardi, Giuseppe Di Natale and Giuseppe Pappalardo.


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Weighing the Impact of Diet and Lifestyle on Female Reproductive Function


Gabriella Garruti, Raffaella De Palo and Maria De Angelisc.


View Abstract


The Role of Diet in Patients with Metabolic Syndrome


Paloma Almeda-Valdes, Roberto J. Herrera-Mercadillo, Carlos A. Aguilar-Salinas, Misael Uribe and Nahum Méndez-Sánchez.


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Leishmanicidal and Trypanocidal Activity of Metal Complexes with 1,2,4-Triazolo[1,5-a]pyrimidines: Insights on their Therapeutic Potential against Leishmaniasis and Chagas Disease


Juan M. Salas , Ana B. Caballero , Ginés M. Esteban-Parra and José M Méndez-Arriaga.


View Abstract


Fungal anticancer metabolites: synthesis towards drug discovery


Margherita Barbero, Emma Artuso and Cristina Prandi.


View Abstract


Drug Delivery Systems for Anti-Cancer Active Complexes of Some Coinage Metals


Ming Zhang, Camille Saint-Germain, Guiling He and Raymond Wai-Yin Sun.


View Abstract


Osteonecrosis of the jaw and angiogenesis inhibitors: a revival of a rare but serous side effect


Lorenzo Antonuzzo , Alice Lunghi , Paolo Petreni , Marco Brugia , Alice Laffi , Elisa Giommoni , Marinella Micol Mela , Francesca Mazzoni , Vanni Balestri and Francesco Di Costanzo.


View Abstract


Global View on Rare Diseases – a Mini Review


Blanka Klimova, Martin Valis, Michael Storek and Kamil Kuca.


View Abstract


Metabolic imbalance of homocysteine and hydrogen sulfide in kidney disease


O Karmin and Yaw L Siow.


View Abstract


Nanoscale Functional Biomaterials for Cancer Theranostics


Linying Liu, Xiaoshuang Li, Lei Chen and Xin Zhang.


View Abstract


Mitochondria: A novel therapeutic target in diabetic nephropathy


Shikun Yang, Yachun Han , Jun Liu , Panai Song , Xiaoxuan Xu, Li Zhao , Chun Hu , Li Xiao , Fuyou Liu , Hao Zhang and Lin Sun.


View Abstract


Kynurenic Acid and Neuroprotective Activity of the Ketogenic Diet in the Eye


Tomasz Żarnowski , Maria Tulidowicz-Bielak , Iwona Żarnowska, Krystyna Mitosek-Szewczyk , Artur Wnorowski , Krzysztof Jóźwiak, Maciej Gasior and Waldemar A Turski.


View Abstract


Structural versatility of hepatitis C virus proteins: implications for the design of novel anti-HCV intervention strategies


Nicole Balasco, Daniela Barone, Annamaria Sandomenico, Alessia Ruggiero, Nunzianna Doti, Rita Berisio, Menotti Ruvo and Luigi Vitagliano.


View Abstract


Short-term Dietary Interventions for the Management of Nonalcoholic Fatty Liver


Caroline S. Stokes, Frank Lammert and Marcin Krawczyk.


View Abstract


Circulating Ace2 in Cardiovascular and Kidney Diseases


Lidia Anguiano, Marta Riera , Julio Pascual and María José Soler.


View Abstract


The role of redox dysregulation in the inflammatory response to acute myocardial ischaemia-reperfusion injury - adding fuel to the fire


Sauri Hernández-Reséndiz, Kroekkiat Chinda, Sang-Bing Ong, Hector Cabrera-Fuentes, Cecilia Zazueta and Derek Hausenloy.


View Abstract


From Ocean to Bedside: the Therapeutic Potential of Molluscan Hemocyanins


Negar Talaei Zanjani, Monica Miranda Saksena , Fariba Dehghani and Anthony L Cunningham.


View Abstract


Next Generation Antineoplastic Agents: A Review on Structurally Modified Vinblastine (VBL) Analogues


Ashanul Haque , Md. Ataur Rahman , Md. Serajul Haque Faizi and Muhammad S Khan.


View Abstract


In vitro and in vivo Experimental Models-based Approaches for Investigating the Anti-inflammatory Profile and Potential of Coumarins.


Silvana Virginia Gagliotti Vigil de Mello and Tânia Silvia Fröde.


View Abstract


Drug Encapsulated Nanoparticles for Treating Targeted Cells


Koh Hann Suk and Subash CB Gopinath.


View Abstract


Endocytosis of Nanoscale Systems for Cancer Treatments


Kai Chen, Xue Li, Hongyan Zhu, Qiyong Gong and Kui Luo.


View Abstract


Cu2+ biological imaging probes based on different sensing mechanisms


Jiawei Li, Fangjun Huo and Caixia Yin.


View Abstract


Endothelial Progenitor Cells as mediators of the crosstalk between vascular repair and immunity: lessons from systemic autoimmune diseases


Javier Rodríguez-Carrio, Patricia López and Ana Suárez.


View Abstract


Poly-Xaa Sequences in Proteins – Biological Role and Interactions with Metal Ions. Chemical and Medical Aspects


Joanna Wątły, Aleksandra Hecel, Paulina Kołkowska, Henryk Kozłowski and Magdalena Rowińska-Żyrek.


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Collaborative and Defensive Fibroblasts in Tumor Progression and Therapy Resistance


Barbara Chiavarina and Andrei Turtoi.


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Fungal Phytotoxins in Sustainable Weed Management


Maurizio Vurro , Angela Boari, Francesca Casella and Maria Chiara Zonno.


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Structure, function, involvement in diseases and targeting of 14-3-3 proteins: an update


Ylenia Cau, Daniela Valensin, Mattia Mori, Sara Draghi and Maurizio Botta.


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Microwave-Assisted Olefin Metathesis as Pivotal Step in the Synthesis of Bioactive Compounds


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Neurochemical Markers in the Mammalian Brain: Structure, Roles in Synaptic Communication, and Pharmacological Relevance


Christopher L. Rees , Charise M. White and Giorgio A Ascoli.


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Guofang Wang , Jian Dong and Liping Deng.


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Nanosafety: Towards Safer Nanoparticles by Design


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Mohammad Shamsul Ola, Abdullah S. Alhomida, Carlos M. Ferrario and Sarfaraz Ahmad.


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Stefania Suta, Filippo Maggi, Marcello Nicoletti, Valeria Baldan and Stefano Dall`Acqua.


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Gang Xu , Kaixun Huang and Jun Zhou.


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Update on the protective renal effects of metformin in diabetic nephropathy.


Andreas Eisenreich and Ulrike Leppert.


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George Liapakis, Minos-Timotheos Matsoukas, Vlasios Karageorgos, Maria Venihaki and Thomas Mavromoustakos.


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Microwave-Induced Bismuth Salts-Mediated Synthesis of Molecules of Medicinal Interests


Debasish Bandyopadhyay, Ashlee Chavez and Bimal K Banik.


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Recent Progress in 808 nm Excited Upconversion Nanomaterials as Multifunctional Nanoprobes for Visualized Theranostics in Cancers


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Valérie Raymond, Delphine Goven, Yassine Benzidane, Olivier List and Bruno Lapied.


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Sandra Fonseca, Dhanya Radhakrishnan, Kalika Prasad and Andrea Chini.


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Caroline Deshayes, Myriam Siegwart, David Pauron, Josy-Anne Froger, Bruno Lapied and Véronique Apaire-Marchais.


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Carlos J. Ciudad, Laura Rodríguez, Xenia Villalobos, Alex J. Félix and Véronica Noé.


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Synthesis of medicinally privileged heterocycles through dielectric heating


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