ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)


Volume 21, 38 Issues, 2014


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Current Medicinal Chemistry

Aims & ScopeAbstracted/Indexed in

Ranking and Category:
  • 9th of 58 in Chemistry & Medicinal
  • 49th of 254 in Pharmacology & Pharmacy
  • 96th of 291 in Biochemistry & Molecular Biology

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Editor-in-Chief:
Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK
Email: cmc@benthamscience.org

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Current: 3.715
5 - Year: 4.239

Upcoming Articles (E-Pub Abstracts ahead of Print)

Towards Next Generation Adenosine A2A Receptor Antagonists
G B Jones and G Yuan
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Biotransformation of Endocrine Disrupting Compounds by Selected Phase I and Phase II Enzymes – Formation of Estrogenic and Chemically Reactive Metabolitesby Cytochromes P450 and Sulfotransferases
Jelle Reinen and Nico P.E. Vermeulen
View Abstract
Idiosyncratic Drug Hepatotoxicity: Strategy for Prevention and Proposed Mechanism
Toshihiko Ikeda
View Abstract
Current Developments in Antimicrobial Surface Coatings for Biomedical Applications
J. J.T.M. Swartjes, P. K. Sharma, T. G. van Kooten, H. C. van der Mei, M. Mahmoudi, H. J. Busscher and E. T.J. Rochford
View Abstract
Procyanidins and their Healthy Protective Effects against Type 2 Diabetes
Noemí González-Abuín, Montserrat Pinent, Àngela Casanova-Martí, Lluís Arola, Mayte Blay and Anna Ardévol
View Abstract
Antibacterial Activities of Flavonoids: Structure-Activity Relationship and Mechanism
Yixi Xie, Weijie Yang, Xiaoqing Chen and Licheng Ren
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Extrahepatic Targets and Cellular Reactivity of Drug Metabolites
Hilmi Orhan
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p38 MAPK:A Potential Target of Chronic Pain Running title: p38 targeting for chronic pain
Xiaofeng Lin, Mingxi Wang, Junping Zhang and Ruian Xu
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PARP1: a promising target for the development of PARP1-based candidates for anticancer intervention
Yongzhou Hu
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Sixteen-Years of Clinically Relevant Dipeptidyl Peptidase-IV (DPP-IV) Inhibitors for Treatment of Type-2 Diabetes: A Perspective
Ram Najar Kushwaha, Wahajul Haq and Seturam Bandhacharya Katti
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Development of EGFR Family Small Molecular Inhibitors for Anticancer Intervention: an Overview of Approved Drugs and Clinical Candidates.
Weiyan Cheng, Yongzhou Hu and Rong Sheng
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CONDROSULF®: STRUCTURAL CHARACTERIZATION, PHARMACOLOGICAL ACTIVITIES AND MECHANISM OF ACTION
Nicola Volpi
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Redox-active and redox-silent compounds: synergistic therapeutics in cancer
Marco Tomasetti, Lory Santarelli, Renata Alleva, Lan-Feng Dong and Jiri Neuzil
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Nanotechnology and antioxidant therapy: an emerging approach for neurodegenerative diseases
Carlos Fernandes Catarina Oliveira, Sofia Benfeito, Pedro Soares, Jorge Garrido and Fernanda Borges
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Cannabinoid receptor type 2 activation in atherosclerosis and acute cardiovascular diseases
Federico Carbone, Francois Mach, Nicolas Vuilleumier and Fabrizio Montecucco
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Association between Polycystic Ovary Syndrome and Metabolic Syndrome
Leandro Martín Velez and Alicia Beatriz Motta
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Glycation of Human Serum Albumin in Diabetes: Impacts on the Structure and Function 88888
Hui Cao, Tingting Chen and Yujun Shi
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Nanomedicine for the Viral Reservoir Drug Delivery and the Fight Against HIV Infection
Benson J. Edagwa, Tian Zhou, JoEllyn M McMillan, Xin-Ming Liu and Howard E. Gendelman
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Gauging Reactive Metabolites in Drug-Induced Toxicity
Marsha R. Eno and Michael D. Cameron
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Thyroglobulin autoantibodies as surrogate biomarkers in the management of patients with differentiated thyroid carcinoma
Ulla Feldt-Rasmussen, Frederik A. Verburg, Markus Luster, Cristina Cupini, Luca Chiovato, Leonidas Duntas, Rossella Elisei, Harald Rimmele, Ettore Seregni, Johannes W.A. Smit, Christian Theimer and Luca Giovanella
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A Common Molecular Motif Characterizes Extracellular Allosteric Enhancers of GPCR Aminergic Receptors and Suggests Enhancer Mechanism of Action
Robert Root-Bernstein and Patrick F. Dillon
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α-glucan pathway as a novel Mtb drug target: structural insights and cues for polypharmcological targeting of GlgB and GlgE
Pushpa Agrawal, Pawan Gupta, Kunchithapadam Swaminathan and Raman Parkesh
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Cellular changes, molecular pathways and the immune system following photodynamic treatment
Paulina Skupin-Mrugalska, Lukasz Sobotta, Malgorzata Kucinska, Marek Murias, Jadwiga Mielcarek and Nejat Duzgunes
View Abstract
Fluorescent GPCR Ligands as New Tools in Pharmacology – update, years 2008- early 2014
Kamil J. Kuder and Katarzyna Kiec-Kononowicz
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Spermicidal and Microbicidal Compounds: In search of an efficient multipurpose strategy.
Marta Baptistaa, Renata Tavaresa and Joao Ramalho-Santos
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Polyphenols-rich natural products for treatment of diabetes
Simona Dragan, Florina Andrica, Maria-Corina Serban and Romulus Timar
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Antagonists of IAP Proteins: Novel Anti-tumor Agents
Yichao Wan, Tingting Liu, Xuben Hou, Yanyan Dun, Peng Guan and Hao Fang
View Abstract
Smoking and Atherosclerosis: Mechanisms of Disease and New Therapeutic Approaches
Gerasimos Siasos, Vasiliki Tsigkou, Eleni Kokkou, Evangelos Oikonomou, Manolis Vavuranakis, Charalampos Vlachopoulos, Alexis Verveniotis, Maria Limperi, Vasiliki Genimata, Athanasios G. Papavassiliou and Dimitris Tousoulis
View Abstract
Title Body mass index, lipid metabolism and estrogens: their impact on coronary heart disease
Genovefa D. Kolovou, Vana Kolovou, Peggy M. Kostakou and Sophie Mavrogeni
View Abstract
Colloidal Supramolecular Aggregates for Therapeutic Application in Neuromedicine
Donato Cosco, Luisa Di Marzio, Carlotta Marianecci, Elena Trapasso, Donatella Paolino, Christian Celia, Maria Carafa and Massimo Fresta
View Abstract
Recent Advances in the Structure-Based and Ligand-Based Design of IKKβ inhibitors as Anti-inflammation and Anti-cancer Agents
Jing-Jie Huang, Hong-Xi Chu, Zheng-Yu Jiang, Xiao-Jin Zhang, Hao-Peng Sun and Qi-Dong You
View Abstract
Nanofiber scaffolds for treatment of spinal cord injury
Jia-Song Guo, Chang-Hui Qian, Eng-Ang Ling and Yuan-Shan Zeng
View Abstract
Chondroitin Sulfate Glycosaminoglycans for CNS Homeostasis - Implications for Material Design
Lohitash Karumbaiah, Tarun Saxena, Martha Betancur and Ravi V. Bellamkonda
View Abstract
Diagnostic and Therapeutic Uses of Nanomaterials in the Brain
Elisa Garbayo, Ander Estella-Hermoso de Mendoza and María J. Blanco-Prieto
View Abstract
Novel Strategies for preventing Diabetes and Obesity Complications with Natural Polyphenols
C. Carpéné, S. Gomez-Zorita, S. Deleruyelle and M. A. Carpéné
View Abstract
Anthocyanins as a potential therapy for diabetic retinopathy
Seyed Fazel Nabavi, Solomon Habtemariam, Maria Daglia, Nasrollah Shafighi, Alistair J. Barber and Seyed Mohammad Nabavi
View Abstract
Having a Promising Efficacy on Type II diabetes, It’s Definitely a Green Tea Time
Hen Jiao, Guohua Hu, Dayong Gu and Xiaoling Ni
View Abstract
Potential application of non-flavonoid phenolics in diabetes: anti-inflammatory effects
Jonatan Miranda, Arrate Lasa, Leixuri Aguirre, Alfredo Fernández-Quintela, Iñaki Milton and Maria P. Portillo
View Abstract
Effect of natural compounds on insulin signaling
Paoli Paolo, Caselli Anna, Camici Guido and Cirri Paolo
View Abstract
Intracranial Aneurysms; in Need of Early Diagnostic and Treatment using Bio- and Nanotechnology
Shima Salmasi and Alexander Marcus Seifalian
View Abstract
Intracranial Stents Past, Present and the Future Trend: Stents Made with Nano-particle or Nanocomposite Biomaterials
Junjie Zhao, Deepak Kalaskar, Yasmin Farhatnia, Xiaoxin Bai, Peter E. Bulter and Alexander M. Seifalian
View Abstract
Nose-to-Brain Drug Delivery by Nanoparticles in the Treatment of Neurological Disorders
Wei-Yi Ong, Shalini Suku Maran and Luca Costantino
View Abstract
Nanomedicine and its Application in Treatment of Microglia-Mediated Neuroinflammation
Nimmi Baby, Radhika Patnala, Eng-Ang Ling and S. ThameemDheen
View Abstract
Engineered nanomaterials and the Nervous System: An Update
Myrtill Simko and Mats-Olof Mattsson
View Abstract
Nanotechnology and Alzheimer’s Disease: What Has Been Done and What to Do
B. Ruozi, D. Belletti, F. Pederzoli, P. Veratti, F. Forni, M. A. Vandelli and G. Tosi
View Abstract
Nanomedicine Based Nanoparticles for Neurological Disorders
Bhasker Sriramoju, Rupinder K. Kanwar and Jagat R. Kanwar
View Abstract
Nanoparticles in Melanoma
M. A. Berciano-Guerrero, A. Montesa-Pino, G. Castaneda-Penalvo, L. Munoz-Fernandez and J. Rodriguez-Flores
View Abstract
Hydrogen Sulfide and Endothelial Dysfunction: Relationship with Nitric Oxide
Zaid Altaany, Francesco Moccia, Luca Munaron, Daniele Mancardi and Rui Wang
View Abstract
Endothelial dysfunction: The link between homocysteine and hydrogen sulfide
Sathnur B Pushpakumar, Sourav Kundu and Utpal Sen
View Abstract
Endothelial Dysfunction in Metabolic Diseases: Role of Oxidation and Possible Therapeutic Employment of N Acetylcysteine
Andi Masha and Valentino Martina
View Abstract
Chelating Agents for the Sequestration of Mercury(II) and Monomethyl Mercury(II)
Francesco Crea, Concetta De Stefano, Claudia Foti, Demetrio Milea and Silvio Sammartano
View Abstract
Novel Nor-Homo- and Spiro-Oxetan- Steroids Target the Human Androgen Receptor and Act as Antiandrogens
Marie Thiele, Sebastian Rabe, Wiebke Hessenkemper, Daniela Roell, Sophie Bartsch, Florian Kraft, Tsion E. Abraham, Adriaan B. Houtsmuller, Martin E. van Royen, Athanassios Giannis and Aria Baniahmad
View Abstract
Effects of Iron and Copper Overload on the Human Liver: an Ultrastructural Study
D Fanni, V Fanos, C Gerosa, M Piras, A Dessì, A Atzei, P Van Eyken, Y Gibo and G Faa
View Abstract
Toxicity of Nanoparticles
Maria Antonietta Zoroddu, Serenella Medici, Alessia Ledda, Valeria Marina Nurchi, Joanna I. Lachowicz and Massimiliano Peana
View Abstract
Copper Chelators: Chemical Properties and Biomedical Applications
Matteo Tegoni, Daniela Valensin, Leonardo Toso and Maurizio Remelli
View Abstract
Tumor Antigen-Derived Peptides Delivery for Cancer Immunotherapy
Ma Wenxue
View Abstract
Interaction of Crotamine and Protamine, Small Cationic Peptides, With The Retinal Spreading Depression
EmptyYN="Y" Fernandes de Lima V M, P Spencer and W Hanke
View Abstract
Editorial: Current status and progress of radiopharmaceuticals for molecular imaging and targeted therapy
Junbo Zhang
View Abstract
On the Physiological Role of Cytosolic 5’-Nucleotidase II (Cn-II): Pathological and Therapeutical Implications
Maria Grazia Tozzi, Rossana Pesi and Simone Allegrini
View Abstract
The role of soluble 5`-nucleotidases in the conversion of nucleotide analogs. Metabolic and therapeutic aspects
Andrzej C Składanowski
View Abstract
The Enzymology of Cytosolic Pyrimidine 5’-Nucleotidases: Functional Analysis and Physiopathological Implications
Giulio Magni, Adolfo Amici and Giuseppe Orsomando
View Abstract
5'-Nucleotidases, Nucleosides and their Distribution in the Brain: Pathological and Therapeutic Implications
Zsolt Kovács, Árpád Dobolyi, Katalin A. Kékesi and Gábor Juhász
View Abstract
Therapeutic Perspectives for CN-II in Cancer
Lars Petter Jordheim
View Abstract
Enzymatic Properties and Physiological Roles of Cytosolic 5’-Nucleotidase II
Roichi Itoh
View Abstract
Is The Expression Of Deoxynucleoside Kinases And 5´-Nucleotidases In Animal Tissues Related To The Biological Effects Of Nucleoside Analogs?
Staffan Eriksson
View Abstract
Editorial “ Metabolic, pathological, and therapeutic perspectives intracellular 5’-nucleotidases”
Piero Luigi Ipata
View Abstract
Metal complexes of biologically active ligands as potential antioxidants
Irena Kostova, Stefan Balkansky and Stefan Balkansky
View Abstract
System models, assays, and endpoint parameters to evaluate anticancer compounds during preclinical screening
Juan Sebastian Yakisich
View Abstract
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