ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)


Volume 24, 42 Issues, 2017


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Current Medicinal Chemistry

This journal supports open access

Aims & ScopeAbstracted/Indexed in

Ranking and Category:
  • 10th of 59 in Chemistry & Medicinal
  • 63rd of 253 in Pharmacology & Pharmacy
  • 100th of 289 in Biochemistry & Molecular Biology

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Editor-in-Chief:
Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK


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Current: 3.455
5 - Year: 3.792

Upcoming Articles (E-Pub Abstracts ahead of Print)

Mechanisms and Drug Targets for Pancreatic Cancer Chemoprevention


Deepanshi Dhar, Komal Raina and Rajesh Agarwal.


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Recent findings on the application of Toll-like receptors agonists in cancer therapy


Martina Mikulandra, Jasminka Pavelic and Tanja Matijevic Glavan.


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Microwave-Induced Bismuth Salts-Mediated Synthesis of Molecules of Medicinal Interests


Debasish Bandyopadhyay, Ashlee Chavez and Bimal K Banik.


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Recent Progress in 808 nm Excited Upconversion Nanomaterials as Multifunctional Nanoprobes for Visualized Theranostics in Cancers


Leyong Zeng, Di Wu, Ying Tian, Yuanwei Pan, Aiguo Wu, Jinchao Zhang and Guangming Lu.


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Serotonin Receptor Binding Characteristics of Geissoschizine Methyl Ether, an Indole Alkaloid in Uncaria Hook


Yasushi Ikarashi, Kyoji Sekiguchi and Kazushige Mizoguchi.


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Targeting NPY, CRF/UCNs and NPS neuropeptide systems to treat Alcohol Use Disorder (AUD)


Francisco David Rodriguez and Rafael Coveñas.


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Multicyclic Peptides as Scaffolds for the Development of Tumor Targeting Agents


Anastasia Loktev, Uwe Haberkorn and Walter Mier.


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The pharmacological mechanisms and therapeutic activities of hydroxychloroquine in rheumatic and related diseases


Changfeng Hu, Lu Lu, Jie-Ping Wan and Chengping Wen.


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Discovery of hedgehog antagonists for cancer therapy


Harleen Khatra, Chandra Bose and Surajit Sinha.


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Expression and Single Nucleotide Polymorphism of Poly (ADP-Ribose) Polymerase-1 in Gastrointestinal Tumours: Clinical Involvement


Sandra María Martín-Guerreroa, Josefa Leóna, Rosa Quiles-Pereza, Laura Belmontee, David Martin-Olivaa, Ángeles Ruiz-Extremeraa, Javier Salmeróna and José Antonio Muñoz-Gámez.


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Mitochondria-targeted antioxidants as a prospective therapeutic strategy for multiple sclerosis


Elena K. Fetisova, Boris V. Chernyak, Galina A. Korshunova, Maria S. Muntyan and Vladimir P Skulachev.


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Influence of cellular and molecular factors on membrane target sensitivity to insecticides


Valérie Raymond, Delphine Goven, Yassine Benzidane, Olivier List and Bruno Lapied.


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Multicolorful carbon dots for tumor theranostics


Haitao Wang, Jingran Bi, Beiwei Zhu and Mingqian Tan.


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Therapeutic strategies of plant-derived compounds for diabetes via regulation of monocyte chemoattractant protein-1.


Magdalena Czemplik, Yu Fu Wang, Anna Kulma and Jan Szopa.


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Bovine Serum Albumin as a Versatile Platform for Cancer Imaging and Therapy


Jun Wang and Bingbo Zhang.


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Natural Products from Deep-Sea-Derived Fungi ̶ a New Source of Novel Bioactive Compounds?


Georgios Daletos, Weaam Ebrahim, Elena Ancheeva, Mona El-Neketi and Peter Proksch.


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Fungal production and manipulation of plant hormones


Sandra Fonseca, Dhanya Radhakrishnan, Kalika Prasad and Andrea Chini.


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Bioactive Metabolites from Pathogenic and Endophytic Fungi of Forest Trees


Marco Masi, Lucia Maddau, Benedetto Teodoro Linaldeddu, Bruno Scanu , Antonio Evidente and Alessio Cimmino.


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Microbial Pest Control Agents: Are they a specific and safe tool for insect pest management?


Caroline Deshayes, Myriam Siegwart, David Pauron, Josy-Anne Froger, Bruno Lapied and Véronique Apaire-Marchais.


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Paramagnetic and Superparamagnetic Inorganic Nanoparticles for T1-Weighted Magnetic Resonance Imaging


Leyong Zeng, Di Wu, Ruifen Zou, Tianxiang Chen, Jinchao Zhang and Aiguo Wu.


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Microwave-Assisted Olefin Metathesis as Pivotal Step in the Synthesis of Bioactive Compounds


Koffi Sénam Etsè, Alice Ngendera, Nelly Tshibalonza Ntumba , Albert Demonceau, Lionel Delaude, Ileana Dragutan and Valerian Dragutan.


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Gadolinium(III)-based Polymeric Magnetic Resonance Imaging Agents for Tumor Imaging


Guangyue Zu, Ye Kuang, Jingjin Dong, Tingting Zhang, Yi Cao, Min Liu, Liqiang Luo and Renjun Pei.


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Polypurine Reverse Hoogsteen Hairpins as a Gene Silencing Tool for Cancer


Carlos J. Ciudad, Laura Rodríguez, Xenia Villalobos, Alex J. Félix and Véronica Noé.


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Synthesis of medicinally privileged heterocycles through dielectric heating


Debasish Bandyopadhyay and Bimal K Banik.


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Tacrine-based Multifunctional Agents in Alzheimer’s Disease: an Old Story in Continuous Development.


Andrea Milelli, Angela De Simone, Nicole Ticchi, Huan Huan Chen, Nibal Betari, Vincenza Andrisano and Vincenzo Tumiatti.


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P2X7 receptor orchestrates multiple signalling pathways triggering inflammation, autophagy and metabolic/trophic responses.


Elisa Orioli, Elena De Marchi, Anna Lisa Giuliani and Elena Adinolfi.


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Absolute Configuration Determination by Quantum Mechanical Calculation of Chiroptical Spectra: Basics and Applications to Fungal Metabolites


Stefano Superchi, Patrizia Scafato, Marcin Górecki and Gennaro Pescitelli.


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Green Synthesized nanomaterials as Theranostic Platforms for Cancer Treatment: Principles, Challenges and the Road Ahead.


Pala Rajasekharreddy, Chao Huang, Siddhardha Busi, Jobina Rajkumari, Ming-Hong Tai and Gang Liu.


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Polysaccharide-based materials associated with or coordinated to gold nanoparticles: Synthesis and medical application.


Débora P. Facchi, Joziel A. da Cruz, Elton G. Bonafé, Antonio G. B. Pereira, André R. Fajardo, Sandro A. S. Venter, Johny P. Monteiro, Edvani C. Muniz and Alessandro F Martins.


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Innovative Opioid Peptides and Biased Agonism: Novel Avenues for More Effective and Safer Analgesics to Treat Chronic Pain


Andrea Bedini and Santi Mario Spampinato.


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Liposomal nanotechnology for cancer theranostics


Zhifei Dai and Xiuli Yue.


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Family B G protein-coupled receptors and their ligands: From structure to function.


Thomas Mavromoustakos, Maria Venihaki, Vlasios Karageorgos, Minos-Timotheos Matsoukas and George Liapakis.


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PYRROLO[2,3-d]PYRIMIDINES AS KINASE INHIBITORS.


Anna Fallacara, Chiara Brullo, Giancarlo Grossi, Monica Sanna, Francesca Musumeci and Silvia Schenone.


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Current Therapeutic Alternatives and New Perspectives in Glioblastoma Multiforme.


Claudia Andrea Quezada Monrás, Rody San Martín, Sebastián Muñoz, Ignacio Niechi, Jake Howden, Daniel Alejandro Uribe, José Ignacio Erices and Ángelo Sebastián Torres Arévalo.


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Regulatory role of G protein-coupled receptors in pancreatic cancer development and progression


Hildegard M Schuller.


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Recent advances of hepsin-targeted inhibitors


Hongmok Kwon, JooYeon Han, Ki-Yong Lee, Sang-Hyun Son and Youngjoo Byun.


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Current Advances in the Biological Activity of Polysaccharides in Dendrobium with Intriguing Therapeutic Potential


Chun-Ting Lee, Heng-Chun Kuo, Yung-Hsiang Chen and Ming-Yen Tsai.


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Recent Advance in the Cancer Bioimaging with Graphene Quantum Dots


Keheng Li, Xinna Zhao, Gang Wei and Zhiqiang Su.


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Immunoprevention of Pancreatic Cancer


Chinthalapally Rao, Altaf Mohammed, Adam Asch and Naveena Janakiram.


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Epigenetic Modulation using Small Molecules - Targeting Histone Acetyltransferases in Disease


André Richters and Angela N Koehler.


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Glycans in Infectious Diseases. A molecular recognition perspective


Luca Unione, Ana Gimeno, Pablo Valverde, Ilaria Calloni, Helena Coelho, Stefania Mirabella, Ana Poveda, Ana Arda and Jesús Jiménez-Barbero.


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Targeting heparan sulfate proteoglycans and their modifying enzymes to enhance anticancer chemotherapy efficacy and overcome drug resistance


Cinzia Lanzi, Nadia Zaffaroni and Giuliana Cassinelli.


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PASTA in penicillin binding proteins and serine/threonine kinases: a recipe of structural, dynamic and binding properties


Luisa Calvanese, Lucia Falcigno, Flavia Squeglia, Gabriella D`Auria and Rita Berisio.


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Highlights in endocytosis of nanostructured systems


Aline Raquel Voltan, Kaila Medina Alarcon, Ana Marisa Fusco-Almeida, Christiane Piena Soares, Maria José Soares Mendes-Giannini and Marlus Chorilli.


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Progress in the Discovery of Macrocyclic Histone Deacetylase Inhibitors for the Treatment of Cancer


Kai Cheng, Siyu Li and Chenzhong Liao.


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Targeting melatonin MT2 receptors: A novel pharmacological avenue for inflammatory and neuropathic pain


Luca Posa, Danilo De Gregorio, Gabriella Gobbi and Stefano Comai.


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Current Challenges and Opportunities for Chemoprevention of Pancreatic Cancer


Altaf Mohammed, Naveena B. Janakiram, Venkateshwar Madka, Min Li, Adam S. Asch and Chinthalapally V Rao.


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Lactate dehydrogenase inhibition: biochemical relevance and therapeutical potential


Giuseppina Laganà, Davide Barreca, Antonella Calderaro and Ersilia Bellocco.


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Advances in chemistry and pharmacology of triterpenoid synthetic dimers


Barbara Bednarczyk-Cwynar and Andrzej Günther.


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HDACs and HDAC inhibitors in urothelial carcinoma – perspectives for an antineoplastic treatment


Maria Pinkerneil, Michèle J. Hoffmann, Wolfgang A. Schulz and Günter Niegisch.


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Targeting the Akt/PI3K signaling pathway as a potential therapeutic strategy for the treatment of Pancreatic Cancer


Safieh Ebrahimi, Mina Hosseini, Soodabeh Shahidsales, Mina Maftouh, Gordon A Ferns, Majid Ghayour-Mobarhan, Seyed Mahdi Hassanian and Amir Avan.


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Discovery of Species-selective and Resistance-breaking Anticholinesterase Insecticides for the Malaria Mosquito


Paul R. Carlier, Jeffrey R. Bloomquist, Max Totrov and Jianyong Li.


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The Typical Metabolic Modifiers Conferring Improvement in Cancer Resistance


Wen Tan, Zhangfeng Zhong, Shengpeng Wang, Hui Liu, Hua Yu, Rui Tan, Xiaodong Hu, Tingrui Pan and Yitao Wang.


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Regulation of ion channels, cellular carriers and Na(+)/K(+)/ATPase by Janus kinase 3


Mentor Sopjani, Shpëtim Thaçi, Berat Krasniqi, Miranda Selmonaj, Mark Rinnerthaler and Miribane Dërmaku-Sopjani.


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Targeting cancer stem cells for chemoprevention of pancreatic cancer


Dharmalingam Subramaniam, Gaurav Kaushik, Prasad Dandawate and Shrikant Anant.


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Advanced in silico approaches for drug discovery: Mining information from multiple biological and chemical data through mtk-QSBER and pt-QSPR strategies


Alejandro Speck-Planche and Maria Natália Dias Soeiro Cordeiro.


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Non-coding RNA in Brain Development and Disorder


Charannya Sozheesvari Subhramanyam and Qidong Hu.


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Chemical and biological aspects of the natural 1,4-benzoquinone embelin and its (semi-)synthetic derivatives


Priti Singh Shuveksh, Subhash Padhye, Rainer Schobert and Bernhard Biersack.


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Polymer Conjugated Gold Nanoparticles in Biomedical Applications


Stanley Anniebell and Subash CB Gopinath.


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Antimicrobial polymers: Mimicking amino acid functionality, sequence control and three-dimensional structure of host-defense peptides


Matthias Hartlieb, Elizabeth G. L. Williams, Agnès Kuroki, Sébastien Perrier and Katherine E S Locock.


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Antitubercular Marine Natural Products


Lishu Wang, Jungfeng Wang, Juan Liu and Yonghong Liu.


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Sphingolipids in Genetic and Acquired Forms of Chronic Kidney Diseases


Norishi Ueda.


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Modulation of Tumour–Related Signaling Pathways By Natural Pentacyclic Triterpenoids And Their Semisynthetic Derivatives


Andrey V. Markov, Evgeniya B. Logashenko and Marina A Zenkova.


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Application of monoterpenoids and their derivatives for treatment of neurodegenerative disorders


Konstantin P. Volcho, Sergey S. Laev, Ghulam Md Ashraf, Gjumrakch Aliev and Nariman F Salakhutdinov.


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The extracellular bacterial HtrA proteins as potential therapeutic targets and vaccine candidates


Joanna Skórko-Glonek, Donata Figaj, Urszula Zarzecka, Tomasz Przepiora, Joanna Renke and Barbara Lipinska.


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Vitamin D, autoimmunity and gender


Clara Crescioli and Salvatore Minisola.


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Cyclodextrins based electrochemical sensors for biomedical and pharmaceutical analysis


Joanna Lenik.


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Metabolomics of Healthy Berry Fruits


Gilda D`Urso, Sonia Piacente, Cosimo Pizza and Paola Montoro.


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The women’s heart: insights into new potential targeted therapy


Daniele Gianfrilli, Ricardo Pofi, Tiziana Feola, Andrea Lenzi and Elisa Giannetta.


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Recent advances in obesity: the role of turmeric tuber and its metabolites in the prophylaxis and therapeutical strategies


Agata Jarząb and Wirginia Kukula-Koch.


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