ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)


Volume 21, 38 Issues, 2014


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Current Medicinal Chemistry

Aims & ScopeAbstracted/Indexed in

Ranking and Category:
  • 9th of 58 in Chemistry & Medicinal
  • 49th of 254 in Pharmacology & Pharmacy
  • 96th of 291 in Biochemistry & Molecular Biology

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Editor-in-Chief:
Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK
Email: cmc@benthamscience.org

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Current: 3.715
5 - Year: 4.239

Upcoming Articles (E-Pub Abstracts ahead of Print)

Reactive Metabolites in Early Drug Development: Predictive in Vitro Tools
Olavi Pelkonen, Markku Pasanen, Ari Tolonen, Mikko Koskinen, Jukka Hakkola, Khaled Abass, Jaana Laine, Merja Häkkinen, Risto Juvonen, Seppo Auriola, Markus Storvik, Pasi Huuskonen, Timo Rousu and Maiju Rahikkala
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An Overview of the Selectivity and Efficiency of the Bacterial Carbonic Anhydrase Inhibitors
C. Capasso and C. T. Supuran
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Vascular and Metabolic Actions of the Green Tea Polyphenol Epigallocatechin Gallate
Michelle A. Keske, Huei L.H. Ng, Dino Premilovac, Stephen Rattigan, Jeong -a Kim, Kashif Munir, Peixin Yang and Michael J. Quon
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P2X Receptors and Diabetes
Carmen Fotino, Andrea Vergani, Paolo Fiorina and Antonello Pileggi
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Emerging Roles of P2X Receptors in Cancer
Elena Adinolfi, Marina Capece, Francesca Amoroso, Elena De Marchi and Alessia Franceschini
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Purinergic P2X Receptors: Structural and Functional Features Depicted by X-Ray and Molecular Modelling Studies
Leanne Grimes and Mark T Young
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Recent Advances in Design of Potential Quinoxaline Anti-Infectives
Josef Jampilek
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Chemistry and Biology of Pyoverdines, Pseudomonas Primary Siderophores
Christine Cézard, Natacha Farvacques and Pascal Sonnet
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NMR in the Design of Antibacterials
Emilija Arsovska, Anamarija Zega, Gregor Mali and Simona Golic Grdadolnik
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Biotransformation of Endocrine Disrupting Compounds by Selected Phase I and Phase II Enzymes – Formation of Estrogenic and Chemically Reactive Metabolitesby Cytochromes P450 and Sulfotransferases
Jelle Reinen and Nico P.E. Vermeulen
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Idiosyncratic Drug Hepatotoxicity: Strategy for Prevention and Proposed Mechanism
Toshihiko Ikeda
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Current Developments in Antimicrobial Surface Coatings for Biomedical Applications
J. J.T.M. Swartjes, P. K. Sharma, T. G. van Kooten, H. C. van der Mei, M. Mahmoudi, H. J. Busscher and E. T.J. Rochford
View Abstract
Procyanidins and their Healthy Protective Effects against Type 2 Diabetes
Noemí González-Abuín, Montserrat Pinent, Àngela Casanova-Martí, Lluís Arola, Mayte Blay and Anna Ardévol
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Antibacterial Activities of Flavonoids: Structure-Activity Relationship and Mechanism
Yixi Xie, Weijie Yang, Xiaoqing Chen and Licheng Ren
View Abstract
p38 MAPK:A Potential Target of Chronic Pain Running title: p38 targeting for chronic pain
Xiaofeng Lin, Mingxi Wang, Junping Zhang and Ruian Xu
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PARP1: a promising target for the development of PARP1-based candidates for anticancer intervention
Yongzhou Hu
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Development of EGFR Family Small Molecular Inhibitors for Anticancer Intervention: an Overview of Approved Drugs and Clinical Candidates.
Weiyan Cheng, Yongzhou Hu and Rong Sheng
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Redox-active and redox-silent compounds: synergistic therapeutics in cancer
Marco Tomasetti, Lory Santarelli, Renata Alleva, Lan-Feng Dong and Jiri Neuzil
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Nanotechnology and antioxidant therapy: an emerging approach for neurodegenerative diseases
Carlos Fernandes Catarina Oliveira, Sofia Benfeito, Pedro Soares, Jorge Garrido and Fernanda Borges
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Gauging Reactive Metabolites in Drug-Induced Toxicity
Marsha R. Eno and Michael D. Cameron
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Polyphenols-rich natural products for treatment of diabetes
Simona Dragan, Florina Andrica, Maria-Corina Serban and Romulus Timar
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Title Body mass index, lipid metabolism and estrogens: their impact on coronary heart disease
Genovefa D. Kolovou, Vana Kolovou, Peggy M. Kostakou and Sophie Mavrogeni
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Nanofiber scaffolds for treatment of spinal cord injury
Jia-Song Guo, Chang-Hui Qian, Eng-Ang Ling and Yuan-Shan Zeng
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Chondroitin Sulfate Glycosaminoglycans for CNS Homeostasis - Implications for Material Design
Lohitash Karumbaiah, Tarun Saxena, Martha Betancur and Ravi V. Bellamkonda
View Abstract
Anthocyanins as a potential therapy for diabetic retinopathy
Seyed Fazel Nabavi, Solomon Habtemariam, Maria Daglia, Nasrollah Shafighi, Alistair J. Barber and Seyed Mohammad Nabavi
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Having a Promising Efficacy on Type II diabetes, It’s Definitely a Green Tea Time
Hen Jiao, Guohua Hu, Dayong Gu and Xiaoling Ni
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Potential application of non-flavonoid phenolics in diabetes: anti-inflammatory effects
Jonatan Miranda, Arrate Lasa, Leixuri Aguirre, Alfredo Fernández-Quintela, Iñaki Milton and Maria P. Portillo
View Abstract
Effect of natural compounds on insulin signaling
Paoli Paolo, Caselli Anna, Camici Guido and Cirri Paolo
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Intracranial Aneurysms; in Need of Early Diagnostic and Treatment using Bio- and Nanotechnology
Shima Salmasi and Alexander Marcus Seifalian
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Intracranial Stents Past, Present and the Future Trend: Stents Made with Nano-particle or Nanocomposite Biomaterials
Junjie Zhao, Deepak Kalaskar, Yasmin Farhatnia, Xiaoxin Bai, Peter E. Bulter and Alexander M. Seifalian
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Nose-to-Brain Drug Delivery by Nanoparticles in the Treatment of Neurological Disorders
Wei-Yi Ong, Shalini Suku Maran and Luca Costantino
View Abstract
Nanomedicine and its Application in Treatment of Microglia-Mediated Neuroinflammation
Nimmi Baby, Radhika Patnala, Eng-Ang Ling and S. ThameemDheen
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Novel Nor-Homo- and Spiro-Oxetan- Steroids Target the Human Androgen Receptor and Act as Antiandrogens
Marie Thiele, Sebastian Rabe, Wiebke Hessenkemper, Daniela Roell, Sophie Bartsch, Florian Kraft, Tsion E. Abraham, Adriaan B. Houtsmuller, Martin E. van Royen, Athanassios Giannis and Aria Baniahmad
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Tumor Antigen-Derived Peptides Delivery for Cancer Immunotherapy
Ma Wenxue
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Interaction of Crotamine and Protamine, Small Cationic Peptides, With The Retinal Spreading Depression
EmptyYN="Y" Fernandes de Lima V M, P Spencer and W Hanke
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Editorial: Current status and progress of radiopharmaceuticals for molecular imaging and targeted therapy
Junbo Zhang
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On the Physiological Role of Cytosolic 5’-Nucleotidase II (Cn-II): Pathological and Therapeutical Implications
Maria Grazia Tozzi, Rossana Pesi and Simone Allegrini
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The role of soluble 5`-nucleotidases in the conversion of nucleotide analogs. Metabolic and therapeutic aspects
Andrzej C Składanowski
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The Enzymology of Cytosolic Pyrimidine 5’-Nucleotidases: Functional Analysis and Physiopathological Implications
Giulio Magni, Adolfo Amici and Giuseppe Orsomando
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5'-Nucleotidases, Nucleosides and their Distribution in the Brain: Pathological and Therapeutic Implications
Zsolt Kovács, Árpád Dobolyi, Katalin A. Kékesi and Gábor Juhász
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Therapeutic Perspectives for CN-II in Cancer
Lars Petter Jordheim
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Enzymatic Properties and Physiological Roles of Cytosolic 5’-Nucleotidase II
Roichi Itoh
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Is The Expression Of Deoxynucleoside Kinases And 5´-Nucleotidases In Animal Tissues Related To The Biological Effects Of Nucleoside Analogs?
Staffan Eriksson
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Editorial “ Metabolic, pathological, and therapeutic perspectives intracellular 5’-nucleotidases”
Piero Luigi Ipata
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