ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)


Volume 24, 42 Issues, 2017


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Current Medicinal Chemistry

This journal supports open access

Aims & ScopeAbstracted/Indexed in

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  • 10th of 59 in Chemistry & Medicinal
  • 63rd of 253 in Pharmacology & Pharmacy
  • 100th of 289 in Biochemistry & Molecular Biology

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Editor-in-Chief:
Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK


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Current: 3.249
5 - Year: 3.508

Upcoming Articles (E-Pub Abstracts ahead of Print)

Pharmacogenetic and pharmacokinetic dose individualization of the taxane chemotherapeutic drugs paclitaxel and docetaxel


Natália Bordin Andriguetti , Suziane Raymundo, Marina Venzon Antunes, Magda Susana Perasolo, Simone Gasparin Verza, Edna Sayuri Suyenaga and Rafael Linden.


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Cyclic Dipeptides: Secondary Metabolites Isolated from Different Microorganisms with Diverse Biological Activities


Aurelio Ortiz and Estibaliz Sansinenea.


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Supervised Machine Learning Methods Applied to Predict Ligand-Binding Affinity


Gabriela Sehnem Heck , Val Oliveira Pintro, Richard Rene Pereira, Mauricio Boff de Ávila, Nayara Maria Bernhardt Levin and Walter Filgueira de Azevedo.


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Bis-2-aminoimidazolines and Bisguanidines: Synthetic Approaches, Antiparasitic Activity and DNA Binding Properties


Christophe Dardonville and J Jonathan Nué Martínez.


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A psycho-behavioral perspective on modelling obsessive-compulsive disorder (OCD) in animals: The role of context


De Wet Wolmarans, Dan J. Stein and Brian H Harvey.


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VDAC1 as a player in mitochondria-mediated apoptosis and target for modulating apoptosis


Varda Shoshan-Barmatz, Yakov Krelin and Quan Chen.


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Na+,K+-ATPase as a target for treatment of tissue fibrosis


Sergei N. Orlov, Jenifer La, Larisa V. Smolyaninova and Nickolai O Dulin.


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Update on the Molecular Mechanisms Underlying the Effect of Cholecystokinin and Cholecystokinin-1 Receptor on the Formation of Cholesterol Gallstones


Helen H. Wang, Piero Portincasa and David Q-H Wang.


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Lipid oxidation products in the pathogenesis of inflammation-related gut diseases


Barbara Sottero, Daniela Rossin, Giuseppe Poli and Fiorella Biasi.


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Role of anti-PCSK9 antibodies in the treatment of patients with statin intolerance


Julia Schreml and Ioanna Gouni-Berthold.


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The Complexity of Omega-3 Fatty acids modulation of Signaling Pathways related to Pancreatic Cancer


Carolina Torres , Andrew M. Diaz , Daniel R. Principe and Paul J Grippo.


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Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions


Valeria Pittala, Luca Vanella, Loredana Salerno, Giuseppe Romeo, Agostino Marrazzo, Claudia Di Giacomo and Valeria Sorrenti.


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The role of mitochondrial dysfunction in the progression of Alzheimer’s disease


Claus Desler, Meryl S. Lillenes, Tone Tønjum and Lene Juel Rasmussen.


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The Influence of Obese Insulin-Resistance on the Outcome of the Ischemia/Reperfusion Insult to the Heart


Krekwit Shinlapawittayatorn, Siriporn C. Chattipakorn and Nipon Chattipakorn.


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Biological roles of the eclectic Chromogranin-A-derived peptide Catestatin


Teresa Pasqua , Tommaso Angelone , Angela Spena and Maria Carmela Cerra.


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New Perspectives on Biomedical Applications of Iron Oxide Nanoparticles


Massimiliano Magro, Davide Baratella, Emanuela Bonaiuto, Jessica de Almeida Roger and Fabio Vianello.


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Biomarkers for diagnosing and staging of Fabry disease


Johannes Krämer and Frank Weidemann.


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Modulating mitophagy in mitochondrial disease


Eszter Dombi, Heather Mortiboys and Joanna Poulton.


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Mechanisms of action, resistance and toxicity of insecticides targeting GABA receptors


Steven D. Buckingham, Makoto Ihara, David B Sattelle and Kazuhiko Matsuda.


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Sulfur – Containing Amino Acids Homocysteine And Taurine In Seizures: Current State Of The Art


Dragan Hrncic, Aleksandra Rasic-Markovic, Duro Macut, Dusan Mladenovic, Veselinka Susic, Dragan Djuric and Olivera Stanojlovic.


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Anticancer Polyphenols from Cultured Plant Cells: Production and New Bioengineering Strategies


Victor Bulgakov, Yulia V. Vereshchagina and Galina N Veremeichik.


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New tracers and new perspectives for molecular imaging in Lewy body diseases


Matteo Bauckneht, Dario Arnaldi, Flavio Nobili, Dag Aarsland and Silvia Morbelli.


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Sulphur-containing amino acids: protective role against free radicals and heavy metals


Mirjana B. Čolović, Vesna M. Vasić, Dragan M. Djuric and Danijela Z Krstić.


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Electrochemical Detectors in Liquid Chromatography: Recent Trends in Pharmaceutical and Biomedical Analysis


Jean-Michel Kauffmanna, Nurgul K. Bakirhan, Burcin Bozal-Palabiyik, Bengi Uslu, Rocio Rodriguez Gomez, Marie Vandeput and Sibel A Ozkan.


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Beneficial effects of N-acetylcysteine and N-mercaptopropionylglycine on ischemia reperfusion injury in the heart


Monika Bartekova, Miroslav Barancik, Kristina Ferenczyova and Narajan S Dhalla.


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NMR-based drug development and improvement against malignant melanoma – implications for the MIA protein family


Oliver Arnolds, Xueyin Zhong, King Tuo Yip, Miriam Schöpel, Bastian Kohl, Stefanie Pütz, Raid Abdel-Jalil and Raphael Stoll.


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Pigment epithelium-derived factor: A novel therapeutic target for cardiometabolic diseases and related complications


Sho-ichi Yamagishi and Takanori Matsui.


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EPC dysfunction and immune networks: translating opportunities for the clinical setting in personalized medicine


Javier Rodríguez-Carrio, Patricia López and Ana Suárez.


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Nonsteroidal Anti-Inflammatory Drugs: Exploiting Bivalent COXIB/TP Antagonists for the Control of Cardiovascular Risk


Silvia Carnevali, Carola Buccellati , Chiara Bolego , Massimo Bertinaria , G. Enrico Rovati and Angelo Sala.


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Synthetic Peptide Drugs for Targeting Skin Cancer: Malignant Melanoma and Melanotic Lesions


Alex Eberle, Bhimsen Rout, Mei Bigliardi Qi and Paul L Bigliardi.


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Peptides against autoimmune neurodegeneration


Alexey Stepanov, Yakov Lomakin, Alexander Gabibov and Alexey Belogurov.


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Snake Venom: From Deadly Toxins to Life-saving Therapeutics


Humera Waheed, Syed Faraz Moin and M Iqbal Choudhary.


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Cdc42 Signaling Pathway Inhibition as a Therapeutic Target in Ras-Related Cancers


Byron J. Aguilar, Huchen Zhou and Qun Lu.


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The evaluation and utilization of marine-derived bioactive compounds with anti-obesity effect


Qiu Jin , Huahua Yu and Pengcheng Li.


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Recent advances of individual BODIPY and BODIPY-based functional materials in medical diagnostics and treatment


Yuriy S. Marfin , Alexey V. Solomonov, Alexander S. Timin and Evgeniy V Rumyantsev.


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Interactions of VDAC with proteins involved in neurodegenerative aggregation: an opportunity for advancement on therapeutic molecules


Andrea Magrì and Angela Messina.


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The role of dietary approach in irritable bowel syndrome


Piero Portincasa, Antony Lembo, Ornella De Bari, Domenica M. Di Palo, Anna Maggio, Ilaria Cataldo and Giuseppe Calamita.


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Modulation of Aquaporins by dietary patterns and plant bioactive compounds


Ilaria Cataldo, Anna Maggio , Patrizia Gena, Ornella de bari, Grazia Tamma , Piero Portincasa and Giuseppe Calamita.


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Nanostructures for pH-sensitive drug delivery and magnetic resonance contrast enhancement systems


Xiao Sun, Guilong Zhang and Zhengyan Wu.


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Targeting Nrf2 in the Protection against Renal Disease


Melania Guerrero Hue, Víctor Farré-Alins , Alejandra Palomino Antolín , Esther Parada, Alfonso Rubio-Navarro, Jesús Egido , Javier Egea and Juan Antonio Moreno.


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Exposing “bright” metals: promising advances in photoactivated anticancer transition metal complexes


Aleksandra Bjelosevic, Benjamin J. Pages, Lawson K. Spare, Krishant M. Deo, Dale L. Ang and Janice R Aldrich-Wright.


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Back to the bench? MEK and ERK inhibitors for the treatment of KRAS mutant lung adenocarcinoma


Jens Köhler , Marco Catalano and Chiara Ambrogio.


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Anti-cancer compounds targeted to VDAC: potential and perspectives


Simona Reina and Vito De Pinto.


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VDAC-targeted drugs affecting cytoprotection and mitochondrial physiology in cerebrovascular and cardiovascular diseases..


Andonis Karachitos, Joaquin Jordan and Hanna Kmita.


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Cyclometalated complexes of platinum and gold with biological properties: state-of-the-art and future perspectives


Sophie Jürgens, Fritz E. Kühn and Angela Casini.


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Multi-Target-Directed Ligands Affecting Serotonergic Neurotransmission for Alzheimer’s Disease Therapy: Advances in Chemical and Biological Research


Agnieszka Jankowska, Anna Wesołowska , Maciej Pawłowski and Grażyna Chłoń-Rzepa.


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Microwave: An Important and Efficient Tool for the Synthesis of Biological potent Organic Compounds


Kamlesh Kumari, Vijay K. Vishvakarma, Prashant Singh, Rajan Patel and Ramesh Chandra.


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Microneedle Patches as Drugs and Vaccine Delivery Platform


Junwei Li , Mingtao Zeng , Hu Shan and Chunyi Tong.


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Potential of sulphur-containing amino acids in the prevention of catecholamine-induced arrhythmias


Adriana Adameova , Paramjit S Tappia, Robert Hatala and Naranjan S Dhalla.


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Promising Treatments for Obsessive-Compulsive Disorder: A Call for Additional Research


Lorrin M. Koran and Elias Aboujaoude.


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Insect peptides – perspectives in human diseases treatment


Szymon Chowański , Zbigniew Adamski, Jan Lubawy , Paweł Marciniak , Joanna Pacholska-Bogalska , Małgorzata Słocińska , Marta Spochacz, Monika Szymczak , Arkadiusz Urbański , Karolina Walkowiak-Nowicka and Grzegorz Rosiński.


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Role of positron emission tomography for central nervous system involvement in systemic autoimmune diseases: status and perspectives


Daniele Mauro , Gaetano Barbagallo , Salvatore D’Angelo, Sannino Pasqualina, Saverio Naty , Caterina Bruno, Ignazio Olivieri , Rosa Daniela Grembiale and Francesco Ursini.


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Impact of diabetes on cardiac and vascular disease: Role of calcium signaling


Tarik Smani, Isabel Gallardo-Castillo, Javier Ávila-Médina, Manuel F. Jimenez-Navarro, Antonio Ordoñez and Abdelkrim Hmadcha.


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Improving Metabolic Control Through Functional Foods


John G. Jones and Joao CP Silva.


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Nutrition as a Health Determinant in Elderly Patients


Ignazio Grattagliano and Tecla Mastronuzzi.


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Natural Product Gossypol and Its Derivatives in Precision Cancer Medicine


Yun Zeng , Jingwen Ma , Liang Xu and Daocheng Wu.


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Role of infrared spectroscopy and imaging in cancer diagnosis


Saroj Kumar , Alagiri Srinivasan and Fredrik Nikolajeff.


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Piperine as a potential anti-cancer agent: a Review on Preclinical studies


Azadeh Manayi, Seyed Mohammad Nabavi, William N. Setzer and Samineh Jafari.


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Phenolic compounds from edible algae: bioactivity and health benefits


Lidia Montero , Andrea del Pilar Sánchez-Camargo, Elena Ibáñez and Bienvenida Gilbert-López.


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Targeting DNA minor groove by hybrid molecules as anticancer agents


Shalini Nekkanti , Ramya Tokala and Nagula Shankaraiah.


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Modulators of the Efflux Pump Cdr1p of Candida albicans: Mechanisms of Action and Chemical Features


Viet-Khoa Tran-Nguyen, Rajendra Prasad, Pierre Falson and Ahcène Boumendjel.


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Prothymosin alpha: an alarmin and more...


Pinelopi Samara, Chrysoula-Evangelia Karachaliou, Kyriaki Ioannou, Nikos E. Papaioannou, Ioannis F. Voutsas, Christos Zikos, Ioannis Pirmettis, Minas Papadopoulos, Hubert Kalbacher, Evangelia Livaniou, Ourania E. Tsitsilonis and Wolfgang Voelter.


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Effects of diets on adipose tissue


Silvia Ezquerro, Amaia Rodríguez, Piero Portincasa and Gema Frühbeck.


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Repurposing of Copper(II)-chelating drugs for the treatment of neurodegenerative diseases.


Valeria Lanza, Danilo Milardi, Giuseppe Di Natale and Giuseppe Pappalardo.


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Fatty acids and effects on in vitro and in vivo models of liver steatosis


Laura Vergani.


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Weighing the Impact of Diet and Lifestyle on Female Reproductive Function


Gabriella Garruti, Raffaella De Palo and Maria De Angelisc.


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Impact of Red Wine Consumption on Cardiovascular Health


Luca Liberale, Aldo Bonaventura, Fabrizio Montecucco, Franco Dallegri and Federico Carbone.


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The Role of Diet in Patients with Metabolic Syndrome


Paloma Almeda-Valdes, Roberto J. Herrera-Mercadillo, Carlos A. Aguilar-Salinas, Misael Uribe and Nahum Méndez-Sánchez.


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Glioblastoma Multiforme, Diagnosis and Treatment; Recent Literature Review


Ron Batash , Noam Asna , Pamela Schaffer, Nicole Francis and Moshe Schaffer.


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Leishmanicidal and Trypanocidal Activity of Metal Complexes with 1,2,4-Triazolo[1,5-a]pyrimidines: Insights on their Therapeutic Potential against Leishmaniasis and Chagas Disease


Juan M. Salas , Ana B. Caballero , Ginés M. Esteban-Parra and José M Méndez-Arriaga.


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Fungal anticancer metabolites: synthesis towards drug discovery


Margherita Barbero, Emma Artuso and Cristina Prandi.


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Drug Delivery Systems for Anti-Cancer Active Complexes of Some Coinage Metals


Ming Zhang, Camille Saint-Germain, Guiling He and Raymond Wai-Yin Sun.


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Osteonecrosis of the jaw and angiogenesis inhibitors: a revival of a rare but serous side effect


Lorenzo Antonuzzo , Alice Lunghi , Paolo Petreni , Marco Brugia , Alice Laffi , Elisa Giommoni , Marinella Micol Mela , Francesca Mazzoni , Vanni Balestri and Francesco Di Costanzo.


View Abstract


Global View on Rare Diseases – a Mini Review


Blanka Klimova, Martin Valis, Michael Storek and Kamil Kuca.


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Metabolic imbalance of homocysteine and hydrogen sulfide in kidney disease


O Karmin and Yaw L Siow.


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Nanoscale Functional Biomaterials for Cancer Theranostics


Linying Liu, Xiaoshuang Li, Lei Chen and Xin Zhang.


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Mitochondria: A novel therapeutic target in diabetic nephropathy


Shikun Yang, Yachun Han , Jun Liu , Panai Song , Xiaoxuan Xu, Li Zhao , Chun Hu , Li Xiao , Fuyou Liu , Hao Zhang and Lin Sun.


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Kynurenic Acid and Neuroprotective Activity of the Ketogenic Diet in the Eye


Tomasz Żarnowski , Maria Tulidowicz-Bielak , Iwona Żarnowska, Krystyna Mitosek-Szewczyk , Artur Wnorowski , Krzysztof Jóźwiak, Maciej Gasior and Waldemar A Turski.


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Structural versatility of hepatitis C virus proteins: implications for the design of novel anti-HCV intervention strategies


Nicole Balasco, Daniela Barone, Annamaria Sandomenico, Alessia Ruggiero, Nunzianna Doti, Rita Berisio, Menotti Ruvo and Luigi Vitagliano.


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Linear Peptides in Intracellular Applications


Cristiane Regina Zuconelli, Roland Brock and Merel Johanna Wilhelmina Adjobo-Hermans.


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Short-term Dietary Interventions for the Management of Nonalcoholic Fatty Liver


Caroline S. Stokes, Frank Lammert and Marcin Krawczyk.


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Defensive and offensive cross-reactive antibodies elicited by pathogens: the Good, the Bad and the Ugly


Daria Augustyniak, Grażyna Majkowska-Skrobek, Justyna Roszkowiak and Agata Dorotkiewicz-Jach.


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Metal complex-peptide conjugates: how to modulate bioactivity of metal-containing compounds by the attachment to peptides


Ines Neundorf.


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Circulating Ace2 in Cardiovascular and Kidney Diseases


Lidia Anguiano, Marta Riera , Julio Pascual and María José Soler.


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The role of redox dysregulation in the inflammatory response to acute myocardial ischaemia-reperfusion injury - adding fuel to the fire


Sauri Hernández-Reséndiz, Kroekkiat Chinda, Sang-Bing Ong, Hector Cabrera-Fuentes, Cecilia Zazueta and Derek Hausenloy.


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From Ocean to Bedside: the Therapeutic Potential of Molluscan Hemocyanins


Negar Talaei Zanjani, Monica Miranda Saksena , Fariba Dehghani and Anthony L Cunningham.


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Next Generation Antineoplastic Agents: A Review on Structurally Modified Vinblastine (VBL) Analogues


Ashanul Haque , Md. Ataur Rahman , Md. Serajul Haque Faizi and Muhammad S Khan.


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In vitro and in vivo Experimental Models-based Approaches for Investigating the Anti-inflammatory Profile and Potential of Coumarins.


Silvana Virginia Gagliotti Vigil de Mello and Tânia Silvia Fröde.


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Drug Encapsulated Nanoparticles for Treating Targeted Cells


Koh Hann Suk and Subash CB Gopinath.


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Endocytosis of Nanoscale Systems for Cancer Treatments


Kai Chen, Xue Li, Hongyan Zhu, Qiyong Gong and Kui Luo.


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Cu2+ biological imaging probes based on different sensing mechanisms


Jiawei Li, Fangjun Huo and Caixia Yin.


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Endothelial Progenitor Cells as mediators of the crosstalk between vascular repair and immunity: lessons from systemic autoimmune diseases


Javier Rodríguez-Carrio, Patricia López and Ana Suárez.


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Poly-Xaa Sequences in Proteins – Biological Role and Interactions with Metal Ions. Chemical and Medical Aspects


Joanna Wątły, Aleksandra Hecel, Paulina Kołkowska, Henryk Kozłowski and Magdalena Rowińska-Żyrek.


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Collaborative and Defensive Fibroblasts in Tumor Progression and Therapy Resistance


Barbara Chiavarina and Andrei Turtoi.


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Synthesis and Biological Activity of Unnatural Enediynes


Roberto Romeo, Salvatore V. Giofrè and Maria A Chiacchio.


View Abstract


Fungal Phytotoxins in Sustainable Weed Management


Maurizio Vurro , Angela Boari, Francesca Casella and Maria Chiara Zonno.


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Structure, function, involvement in diseases and targeting of 14-3-3 proteins: an update


Ylenia Cau, Daniela Valensin, Mattia Mori, Sara Draghi and Maurizio Botta.


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Microwave-Assisted Olefin Metathesis as Pivotal Step in the Synthesis of Bioactive Compounds


Koffi Sénam Etsè, Alice Ngendera, Ntumba Nelly Tshibalonza , Albert Demonceau, Lionel Delaude, Ileana Dragutan and Valerian Dragutan.


View Abstract


In Silico Models for Nanomedicine: Recent Developments


Pietro Mascheroni and Bernhard Aribo Schrefler.


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Neurochemical Markers in the Mammalian Brain: Structure, Roles in Synaptic Communication, and Pharmacological Relevance


Christopher L. Rees , Charise M. White and Giorgio A Ascoli.


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Sex-Genetic Interaction in the Risk for Cerebrovascular Disease


Donatella Pastore, Francesca Pacifici, Barbara Capuani, Raffaele Palmirotta, Chuanhui Dong, Andrea Coppola, Pasquale Abete, Mario Roselli, Paolo Sbraccia, Fiorella Guadagni, Davide Lauro, Tatjana Rundek and David Della-Morte.


View Abstract


Overview of Cantharidin and Its Analogues


Guofang Wang , Jian Dong and Liping Deng.


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Sulfur containing acridine derivatives in preclinical studies with cancer cell lines


Salem Othman and Kožurková Mária.


View Abstract


Anti-fatigue effects of active ingredients from traditional Chinese medicine: a review


Si-Si Zhou and Jian-Guo Jiang.


View Abstract


Small Molecule Drugs And Targeted Therapy For Melanoma: Current Strategies And Future Directions


Carmen Cerchia and Antonio Lavecchia.


View Abstract


Chemopreventive properties of tolfenamic acid: a mechanistic review


David Feldman, Elizabeth Leahy and Seong-Ho Lee.


View Abstract


Hydroxypyridinone derivatives: a fascinating class of chelators with therapeutic applications - an update


Sílvia Chaves, Luca Piemontese, Asha Hiremathad and Maria Amélia Santos.


View Abstract


Nanosafety: Towards Safer Nanoparticles by Design


Neus G. Bastús and Víctor Puntes.


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Role of Tissue Renin-angiotensin System and the Chymase/angiotensin-(1-12) axis in the Pathogenesis of Diabetic Retinopathy.


Mohammad Shamsul Ola, Abdullah S. Alhomida, Carlos M. Ferrario and Sarfaraz Ahmad.


View Abstract


Molecular design and medicinal applications of nano-nitric oxide delivery systems


Kim Truc Nguyen, Zhouran Wu, Tiantian Huang and Chor Yong Tay.


View Abstract


Current Therapeutic Alternatives and New Perspectives in Glioblastoma Multiforme.


Ángelo Sebastián Torres , José Ignacio Erices, Daniel Uribe, Jake Howden, Ignacio Niechi, Sebastián Muñoz, Rody San Martín and Claudia Quezada.


View Abstract


New drugs from old natural compounds: scarcely investigated sesquiterpenes as new possible therapeutic agents


Stefania Suta, Filippo Maggi, Marcello Nicoletti, Valeria Baldan and Stefano Dall`Acqua.


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Hepatic AMP Kinase as a Potential Target for Treating Nonalcoholic Fatty Liver Disease: Evidence from Studies of Natural Products.


Gang Xu , Kaixun Huang and Jun Zhou.


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Update on the protective renal effects of metformin in diabetic nephropathy.


Andreas Eisenreich and Ulrike Leppert.


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Family B G protein-coupled receptors and their ligands: From structure to function.


George Liapakis, Minos-Timotheos Matsoukas, Vlasios Karageorgos, Maria Venihaki and Thomas Mavromoustakos.


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Biomedical applications of nanomaterials as therapeutics


Cheng Teng Ng, Gyeong-Hun Baeg, Liya Cheng Yu, Choon Nam Ong and Boon-Huat Bay.


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Promising Targets in Anti-cancer Drug Development: Recent Updates


Bhupinder Kumar, Sandeep Singh, Ira-Ida Skvortsova and Vinod Kumar.


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Metallic nanoclusters for cancer imaging and therapy


Qing Zhang, Mingying Yang, Ye Zhu and Chuanbin Mao.


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Therapeutic strategies of plant-derived compounds for diabetes via regulation of monocyte chemoattractant protein-1.


Magdalena Czemplik, Anna Kulma, Yu Fu Wang and Jan Szopa.


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Mechanisms and Drug Targets for Pancreatic Cancer Chemoprevention


Deepanshi Dhar, Komal Raina and Rajesh Agarwal.


View Abstract


Microwave-Induced Bismuth Salts-Mediated Synthesis of Molecules of Medicinal Interests


Debasish Bandyopadhyay, Ashlee Chavez and Bimal K Banik.


View Abstract


Recent Progress in 808 nm Excited Upconversion Nanomaterials as Multifunctional Nanoprobes for Visualized Theranostics in Cancers


Leyong Zeng, Di Wu, Ying Tian, Yuanwei Pan, Aiguo Wu, Jinchao Zhang and Guangming Lu.


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Expression and Single Nucleotide Polymorphism of Poly (ADP-Ribose) Polymerase-1 in Gastrointestinal Tumours: Clinical Involvement


Sandra María Martín-Guerreroa, Josefa Leóna, Rosa Quiles-Pereza, Laura Belmontee, David Martin-Olivaa, Ángeles Ruiz-Extremeraa, Javier Salmeróna and José Antonio Muñoz-Gámez.


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Influence of cellular and molecular factors on membrane target sensitivity to insecticides


Valérie Raymond, Delphine Goven, Yassine Benzidane, Olivier List and Bruno Lapied.


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Multicolorful carbon dots for tumor theranostics


Haitao Wang, Jingran Bi, Beiwei Zhu and Mingqian Tan.


View Abstract


Bovine Serum Albumin as a Versatile Platform for Cancer Imaging and Therapy


Jun Wang and Bingbo Zhang.


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Fungal production and manipulation of plant hormones


Sandra Fonseca, Dhanya Radhakrishnan, Kalika Prasad and Andrea Chini.


View Abstract


Bioactive Metabolites from Pathogenic and Endophytic Fungi of Forest Trees


Marco Masi, Lucia Maddau, Benedetto Teodoro Linaldeddu, Bruno Scanu , Antonio Evidente and Alessio Cimmino.


View Abstract


Microbial Pest Control Agents: Are they a specific and safe tool for insect pest management?


Caroline Deshayes, Myriam Siegwart, David Pauron, Josy-Anne Froger, Bruno Lapied and Véronique Apaire-Marchais.


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Paramagnetic and Superparamagnetic Inorganic Nanoparticles for T1-Weighted Magnetic Resonance Imaging


Leyong Zeng, Di Wu, Ruifen Zou, Tianxiang Chen, Jinchao Zhang and Aiguo Wu.


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Gadolinium(III)-based Polymeric Magnetic Resonance Imaging Agents for Tumor Imaging


Guangyue Zu, Ye Kuang, Jingjin Dong, Tingting Zhang, Yi Cao, Min Liu, Liqiang Luo and Renjun Pei.


View Abstract


Polypurine Reverse Hoogsteen Hairpins as a Gene Silencing Tool for Cancer


Carlos J. Ciudad, Laura Rodríguez, Xenia Villalobos, Alex J. Félix and Véronica Noé.


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Synthesis of medicinally privileged heterocycles through dielectric heating


Debasish Bandyopadhyay and Bimal K Banik.


View Abstract


Tacrine-based Multifunctional Agents in Alzheimer’s Disease: an Old Story in Continuous Development.


Andrea Milelli, Angela De Simone, Nicole Ticchi, Huan Huan Chen, Nibal Betari, Vincenza Andrisano and Vincenzo Tumiatti.


View Abstract


P2X7 receptor orchestrates multiple signalling pathways triggering inflammation, autophagy and metabolic/trophic responses.


Elisa Orioli, Elena De Marchi, Anna Lisa Giuliani and Elena Adinolfi.


View Abstract


Absolute Configuration Determination by Quantum Mechanical Calculation of Chiroptical Spectra: Basics and Applications to Fungal Metabolites


Stefano Superchi, Patrizia Scafato, Marcin Górecki and Gennaro Pescitelli.


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Green Synthesized nanomaterials as Theranostic Platforms for Cancer Treatment: Principles, Challenges and the Road Ahead.


Pala Rajasekharreddy, Chao Huang, Siddhardha Busi, Jobina Rajkumari, Ming-Hong Tai and Gang Liu.


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Polysaccharide-based materials associated with or coordinated to gold nanoparticles: Synthesis and medical application.


Débora P. Facchi, Joziel A. da Cruz, Elton G. Bonafé, Antonio G. B. Pereira, André R. Fajardo, Sandro A. S. Venter, Johny P. Monteiro, Edvani C. Muniz and Alessandro F Martins.


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Innovative Opioid Peptides and Biased Agonism: Novel Avenues for More Effective and Safer Analgesics to Treat Chronic Pain


Andrea Bedini and Santi Mario Spampinato.


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Liposomal nanotechnology for cancer theranostics


Zhifei Dai and Xiuli Yue.


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PYRROLO[2,3-d]PYRIMIDINES AS KINASE INHIBITORS.


Anna Fallacara, Chiara Brullo, Giancarlo Grossi, Monica Sanna, Francesca Musumeci and Silvia Schenone.


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Recent advances of hepsin-targeted inhibitors


Hongmok Kwon, JooYeon Han, Ki-Yong Lee, Sang-Hyun Son and Youngjoo Byun.


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Current Advances in the Biological Activity of Polysaccharides in Dendrobium with Intriguing Therapeutic Potential


Chun-Ting Lee, Heng-Chun Kuo, Yung-Hsiang Chen and Ming-Yen Tsai.


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Recent Advance in the Cancer Bioimaging with Graphene Quantum Dots


Keheng Li, Xinna Zhao, Gang Wei and Zhiqiang Su.


View Abstract


Immunoprevention of Pancreatic Cancer


Chinthalapally Rao, Altaf Mohammed, Adam Asch and Naveena Janakiram.


View Abstract


Glycans in Infectious Diseases. A molecular recognition perspective


Luca Unione, Ana Gimeno, Pablo Valverde, Ilaria Calloni, Helena Coelho, Stefania Mirabella, Ana Poveda, Ana Arda and Jesús Jiménez-Barbero.


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PASTA in penicillin binding proteins and serine/threonine kinases: a recipe of structural, dynamic and binding properties


Luisa Calvanese, Lucia Falcigno, Flavia Squeglia, Gabriella D`Auria and Rita Berisio.


View Abstract


Highlights in endocytosis of nanostructured systems


Aline Raquel Voltan, Kaila Medina Alarcon, Ana Marisa Fusco-Almeida, Christiane Piena Soares, Maria José Soares Mendes-Giannini and Marlus Chorilli.


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Progress in the Discovery of Macrocyclic Histone Deacetylase Inhibitors for the Treatment of Cancer


Kai Cheng, Siyu Li and Chenzhong Liao.


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Targeting melatonin MT2 receptors: A novel pharmacological avenue for inflammatory and neuropathic pain


Luca Posa, Danilo De Gregorio, Gabriella Gobbi and Stefano Comai.


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Current Challenges and Opportunities for Chemoprevention of Pancreatic Cancer


Altaf Mohammed, Naveena B. Janakiram, Venkateshwar Madka, Min Li, Adam S. Asch and Chinthalapally V Rao.


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HDACs and HDAC inhibitors in urothelial carcinoma – perspectives for an antineoplastic treatment


Maria Pinkerneil, Michèle J. Hoffmann, Wolfgang A. Schulz and Günter Niegisch.


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Discovery of Species-selective and Resistance-breaking Anticholinesterase Insecticides for the Malaria Mosquito


Paul R. Carlier, Jeffrey R. Bloomquist, Max Totrov and Jianyong Li.


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The Typical Metabolic Modifiers Conferring Improvement in Cancer Resistance


Wen Tan, Zhangfeng Zhong, Shengpeng Wang, Hui Liu, Hua Yu, Rui Tan, Xiaodong Hu, Tingrui Pan and Yitao Wang.


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Regulation of ion channels, cellular carriers and Na(+)/K(+)/ATPase by Janus kinase 3


Mentor Sopjani, Shpëtim Thaçi, Berat Krasniqi, Miranda Selmonaj, Mark Rinnerthaler and Miribane Dërmaku-Sopjani.


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Advanced in silico approaches for drug discovery: Mining information from multiple biological and chemical data through mtk-QSBER and pt-QSPR strategies


Alejandro Speck-Planche and Maria Natália Dias Soeiro Cordeiro.


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Polymer Conjugated Gold Nanoparticles in Biomedical Applications


Stanley Anniebell and Subash CB Gopinath.


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Application of monoterpenoids and their derivatives for treatment of neurodegenerative disorders


Konstantin P. Volcho, Sergey S. Laev, Ghulam Md Ashraf, Gjumrakch Aliev and Nariman F Salakhutdinov.


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The extracellular bacterial HtrA proteins as potential therapeutic targets and vaccine candidates


Joanna Skórko-Glonek, Donata Figaj, Urszula Zarzecka, Tomasz Przepiora, Joanna Renke and Barbara Lipinska.


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Recent advances in obesity: the role of turmeric tuber and its metabolites in the prophylaxis and therapeutical strategies


Agata Jarząb and Wirginia Kukula-Koch.


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