ISSN: 1873-5592 (Online)
ISSN: 1389-4501 (Print)


Volume 17, 16 Issues, 2016


Download PDF Flyer




Current Drug Targets

Aims & ScopeAbstracted/Indexed in

Ranking and Category:
  • 74th of 253 in Pharmacology & Pharmacy

Submit Abstracts Online Submit Manuscripts Online

Editor-in-Chief:
Francis J. Castellino
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556
USA


View Full Editorial Board

Subscribe Purchase Articles Order Reprints

Current: 3.029
5 - Year: 3.341

Upcoming Articles (E-Pub Abstracts ahead of Print)

PHB in Cardiovascular and Other Diseases: Present Knowledge and Implications


Debabrata Chowdhury, Dinesh Kumar, Pranjal Sarma, Anjana Devi Tangutur and Manika Pal Bhadra.


View Abstract


Pharmacological Management Options to Prevent and Reduce Ischemic Hemorrhagic Transformation


Wing Mann Ho, Cesar Reis, Onat Akyol, Gokce Yilmaz Akyol, Richard Applegate 2nd, Gary Stier, Robert Martin and John H Zhang.


View Abstract


A Review on Plasmodium falciparum-Protein Farnesyltransferase Inhibitors as Antimalarial Drug Targets


Kamlesh Sharma.


View Abstract


The Role of Autophagy in Rheumatic Disease


Yuan Feng, Bo Li, Xue Yi Li and Zhen Biao Wu.


View Abstract


Is going for cure in CML targeting aberrant Glycogen Synthase Kinase 3β?


Concetta Saponaro, Michele Maffia, Nicola Di Renzo and Addolorata Maria Luce Coluccia.


View Abstract


Inflammasome Activation in Chronic Glomerular Diseases


Sabena M. Conley, Justine M. Abais, Krishna M. Boini and Pin-Lan Li.


View Abstract


Therapeutic approaches using riboflavin in mitochondrial energy metabolism disorders


Bárbara J. Henriques, Tânia G. Lucas and Cláudio M Gomes.


View Abstract


The Anti-Inflammatory Potential of ACE2/Angiotensin-(1-7)/Mas Receptor Axis: Evidence from Basic and Clinical Research


Thiago Ruiz Rodrigues Prestes, Natalia Pessoa Rocha, Aline Silva Miranda, Antônio Lúcio Teixeira and Ana Cristina Simoes-e-Silva.


View Abstract


Pet Radiopharmaceuticals for Personalized Medicine


Sushil K Sharma.


View Abstract


Antifungal Potential of Alkaloids as An Emerging Therapeutic Target


Haroon Khan, Mohammad S. Mubarak and Surriya Amin.


View Abstract


Roles of Insulin Resistance, Endothelial Dysfunction and Life Style Changes in the Development of Cardiovascular Disease in Diabetic Patients


Dongdong Sun, Wanrong Man and Lei Zhang.


View Abstract


Targeting Interferon Regulatory Factor for Cardiometabolic Diseases: Opportunities and Challenges


Yaxing Zhang, Xiao-Jing Zhang and Hongliang Li.


View Abstract


Prospectives of Antihypertensive Nano-ceuticals as Alternative Therapeutics


Taskeen Niaz, Zeeshan Hafeez and Muhammad Imran.


View Abstract


Therapeutic Drugs In Bone Loss-Associated Disorders: Clinical Outcomes And Challenges


Daniela M. Sousa, Inês S. Alencastre, Luís Leitão, Estrela Neto, Cecília J. Alves and Meriem Lamghari.


View Abstract


Graphene: A Comprehensive Review


Aditya Diliprao Ghuge, Abhay R. Shirode and Vilasrao J Kadam.


View Abstract


Cardiac Tumors: Clinical Perspective and Therapeutic Considerations


Dylan Y. Ren, Nathan D. Fuller, Sara A.B. Gilbert and Yingmei Zhang.


View Abstract


Targeted Temperature Management in Spontaneous Intracerebral Hemorrhage: A Systematic Review


Marlene Fischer, Alois Schiefecker, Peter Lackner, Raimund Helbok, Ronny Beer, Bettina Pfausler, Erich Schmutzhard and Gregor Broessner.


View Abstract


The Role of Gender-Specific Cytokine Pathways as Drug Targets and Gender-Specific Biomarkers in Personalized Cancer Therapy


Anna Maria Berghella, Ida Contasta, Roberto Lattanzio, Giancarlo Di Gregorio, Irma Campitelli, Silvino Marino, Luigi Liborio Liberatore, Luca Navarra, Giampaolo Caterino, Antonio Mongelli, Vincenzo Vittorini, Matteo Basta, Mauro Domenicucci, Nunzia Antonucci, Tiziana Del Beato, Enzo Secinaro, Fabiana Ciccone and Patrizia Pellegrini.


View Abstract


Cytosolic mRNA Target and Bioavailability of Nanoparticulate siRNA Delivery Systems for Gene Silencing


Sorin Emilian Leucuta.


View Abstract


Targeting Apelinergic System in Cardiometabolic Disease


Rui Guo, Olivia Rogers and Sreejayan Nair.


View Abstract


Life and Death Partners in Post-PCI Restenosis: Apoptosis, Autophagy, and The Cross-talk Between Them


Hong Zhu and Yingmei Zhang.


View Abstract


Pancreatic Neoplasms and Autophagy


Linzi A. Barton and Jun Ren.


View Abstract


Aptamer-mediated polymeric vehicles for enhanced cell-targeted drug delivery


Kei Xian Tan, Michael K. Danquah, Amandeep Sidhu, Lau Sie Yon and Clarence M Ongkudon.


View Abstract


Aligning animal models of clinical germinal matrix hemorrhage, from basic correlation to therapeutic approach


Tim Lekic, Damon William Klebe, Pilar Pichon, Katarina Brankov, Sally Sultan, Devin William McBride, Darlene Casel, Alhamza Al-Bayati, Yan Ding, Jiping Tang and John He Zhang.


View Abstract


Cellular and Molecular Networks in Chronic Myeloid Leukemia: the leukemic stem, progenitor and stromal cell interplay


Danilo Perrotti, Giovannino Silvestri, Lorenzo Stramucci, Justine Yu and Rossana Trotta.


View Abstract


Current Perspectives on Novel Drug Delivery Systems and Therapies for Management of Prostate Cancer: An Inclusive Review


Rohit Rajendra Bhosale, H V Gangadharappa, Umme Hani, Riyaz Ali M Osmani, Rudra Vaghela, K Sairam Venkata and P K Kulkarni.


View Abstract


Current approach for the diagnosis of Aplastic Anemia


Alicia Rovo and Andre Tichelli.


View Abstract


Targeted mesoporous silica nanocarriers in oncology


Alejandro Baeza and Maria Vallet-Regí.


View Abstract


Recent Advances in pH-Sensitive Polymeric Nanoparticles for Smart Drug Delivery in Cancer Therapy


Eun-Kyung Lim, Bong Hyun Chung and Sang J Chung.


View Abstract


Bioinspired Platform Conjugated Active Drug Delivery


Jingxin Shao, Mingjun Xuan, Qiang He and Luru Dai.


View Abstract


Predictive Pathology in the Target Therapy Era in Breast Cancer


Anna Sapino.


View Abstract


The connections among autophagy, inflammasome and mitochondria


Isabel de Lavera, Ana Delgado Pavón, Marina Villanueva Paz, Manuel Oropesa-Ávila, Mario de la Mata, Elizabet Alcocer-Gómez, Juan Garrido-Maraver, David Cotán, Mónica Álvarez-Córdoba and José A Sánchez-Alcázar.


View Abstract


The Smart Programmable CRISPR Technology: A Next Generation Genome Editing Tool for Investigators


Chiranjib Chakraborty, Teoh Seong Lin and Srijit Das.


View Abstract


Targeting Hsp90-Cdc37: a promising therapeutic strategy by inhibiting Hsp90 chaperone function


Lei Wang, Li Li, Kai Gu, Xiao-Li Xu, Qi-Dong You and Hao-Peng Sun.


View Abstract


Molecular targets and angiogenesis in renal cell carcinoma, a multi-target approach: mini review


Simone A.M. Badal, William D. Aiken and Sheray N Chin.


View Abstract


SMALL-CELL LUNG CANCER: CLINICAL MANAGEMENT AND UNMET NEEDS, New perspectives for an old problem


Giuseppe Lo Russo, Marianna Macerelli, Marco Platania, Nicoletta Zilembo, Milena Vitali, Diego Signorelli, Claudia Proto, Monica Ganzinelli, Rosaria Gallucci, Francesco Agustoni, Gianpiero Fasola, Filippo de Braud and Marina Chiara Garassino.


View Abstract


The molecular concept of atheromatous plaques


Zar Chi Thent, Chiranjib Chakraborty, Pasuk Mahakkanukrauh, Nik Kosai, Reynu Rajan and Srijit Das.


View Abstract


Modelling chemotherapy-induced cardiotoxicity by human pluripotent stem cells


Rosalinda Madonna, Christian Cadeddu, Martino Deidda, Paolo Spallarossa, Concetta Zito and Giuseppe Mercuro.


View Abstract


Phytometabolites Targeting Warburg Effect in Cancer Cells: A Mechanistic Review


Mohadeseh Hasanpourghadi, Chung Yeng Looi, Ashok Kumar Pandurangan, Gautam Sethi, Won Fen Wong and Mohd Rais Mustafa.


View Abstract


Smart Drug Delivery Systems in Cancer Therapy


Gozde UNSOY and Ufuk GUNDUZ.


View Abstract


Nosocomial infections and antimicrobial treatment in coiled patients with aneurysmal subarachnoid hemorrhage


Peter Lackner, Christoph Mueller, Ronny Beer, Gregor Broessner, Marlene Fischer, Raimund Helbok, Alois Schiefecker, Erich Schmutzhard and Bettina Pfausler.


View Abstract


Recent Advances in Nanosystems and Strategies for Managing Leishmaniasis


Rudra Vaghela, Parthasarathi K. Kulkarni, Riyaz Ali M. Osmani, Rohit R. Bhosale and V Naga Sravan Kumar Varma.


View Abstract


The role of statins in heme oxygenase-1 activation in cardiovascular diseases


A. Piechota-Polanczyk and A Jozkowicz.


View Abstract


Advances in Drug Delivery Systems, from 0 to 3D superstructures


Marius RADULESCU, Simona Popescu, Denisa FICAI, Maria SONMEZ, Ovidiu OPREA, Angela SPOIALĂ, Anton FICAI and Ecaterina ANDRONESCU.


View Abstract


Oxidative stress and antioxidants in neurological diseases: is there still hope?


Andreia Neves Carvalho, Omidreza Firuzi, Maria João Gama, Jack van Horssen and Luciano Saso.


View Abstract


Pharmacoperones as a New Therapeutic Approach: In vitro Identification and In vivo Validation of Bioactive Molecules


Alfredo Ulloa-Aguirre and P Michael Conn.


View Abstract


Polypharmacology of approved anticancer drugs


Ivano Amelio, Andrey Lisitsa, Richard A. Knight, Gerry Melino and Alexey V Antonov.


View Abstract


Elastin-like recombinamers as smart drug delivery systems


F. Javier Arias, Mercedes Santos, Arturo Ibáñez-Fonseca, Jesús Piña and Sofía Serrano.


View Abstract


Rationale and Prospects of Targeting Bacterial Two-component Systems for Antibacterial Treatment of Cystic Fibrosis Patients


Nadya Velikova and Jerry M Wellsa.


View Abstract


Functionalized magnetic nanostructures for anticancer therapy


Eugenia Dumitra Teodor, Florentina Gatea, Anton Ficai and Gabriel Lucian Radu.


View Abstract


Recent Advancement and Technological Aspects of Pulsatile Drug Delivery System - A Laconic Review


Vinay Pandit, Ajay Kumar, M.S Ashawat, C.P. Verma and Pravin Kumar.


View Abstract


Drug Target Validation Methods in Malaria - Protein Interference Assay (PIA) as a Tool for Highly Specific Drug Target Validation


Kamila A. Meissner, Sergey Lunev, Yuan-Ze Wang, Marleen Linzke, Fernando de Assis Batista, Carsten Wrenger and Matthew R Groves.


View Abstract


Can microRNAs Be Biomarkers or Targets for Therapy of Ischemic Coronary Artery Disease in Metabolic Syndrome?


Petra Rocic.


View Abstract


Role of interferons in chronic hepatitis C infection


Carolina Scagnolari, Katia Monteleone, Giulia Cacciotti and Guido Antonelli.


View Abstract


Nuclear Factor Kappa B: A Potential Target to Persecute Head and Neck Cancer


Javadi Monisha, Nand Kishor Roy, Devivasha Bordoloi, Amit Kumar, Ramesh Golla, Jibon Kotoky, Ganesan Padmavathi and Ajaikumar B Kunnumakkara.


View Abstract


Neuroinflammation is Associated with Brain Extracellular TAU-Protein Release after Spontaneous Subarachnoid Hemorrhage


Alois Josef Schiefecker, Anelia Dietmann, Ronny Beer, Bettina Pfausler, Peter Lackner, Mario Kofler, Marlene Fischer, Gregor Broessner, Florian Sohm, Miriam Mulino, Claudius Thomé, Christian Humpel, Erich Schmutzhard and Raimund Helbok.


View Abstract


Characterization and Management of Cutaneous Side Effects Related to the Immunosuppressive Treatment in Solid Organ Recipients.


Paola Savoia, Andrea Ranghino and Paolo Fava.


View Abstract


Targeting MET receptor in rhabdomyosarcoma: rationale and progress


Barbara Szewczyk, Klaudia Skrzypek and Marcin Majka.


View Abstract


The double roles of the prostaglandin E2 EP2 receptor in intracerebral hemorrhage


Xu Luo, Qiquan Zhu, Jie Zhang, Qin Huang, Zongyi Xie and Yuan Cheng.


View Abstract


Targeting Transient Receptor Potential Canonical Channels for Nervous System Diseases


Yibin Wang, Jiyuan Bu, Haitao Shen, Haiying Li, Zhong Wang and Gang Chen.


View Abstract


Vascular Biology Center Medical College of Georgia Georgia Regents University Augusta, GA, USA


Rodolfo Montironi, Matteo Santoni, Liang Cheng, Antonio Lopez-Beltran, Francesco Massari, Marc R. Matrana, Holger Moch and Marina Scarpelli.


View Abstract


Multi-Target Mining of Alzheimer Disease Proteome with Hansch’s QSBR-Perturbation Theory and Experimental-Theoretic Study of New Thiophene Isosters of Rasagiline


Paula Abeijón, Xerardo García-Mera, Olga Caamaño, Matilde Yañez, Edgar López-Castro, Francisco J. Romero-Durán and Humberto González-Díaz.


View Abstract


Effect of Genetic Polymorphisms (SNPs) in CHRNA7 Gene on Response to Acetylcholinesterase Inhibitors (AChEI) in Patients with Alzheimer’s Disease


Patrizia Russo, Aliaksei Kisialiou, Rossana Moroni, Giulia Prinzi and Massimo Fini.


View Abstract


CADD modeling of multi-target drugs against Alzheimer's disease


Pravin Ambure and Kunal Roy.


View Abstract


DOCKING STUDIES FOR MULTI-TARGET DRUGS


L. Scotti, F.J.B. Mendonça Júnior, H. Ishiki, F.F. Ribeiro, Singla Rajeev K, J.M. Barbosa Filho, M.S. Da Silva and MT Scotti.


View Abstract


Innate and Adaptive Immune Responses in Chronic HCV infection


Lynn B Dustin.


View Abstract


How Current Direct-Acting Antiviral and Novel Cell Culture Systems for HCV are Shaping Therapy and Molecular Diagnosis of Chronic HCV Infection


Fabrizio Maggi, Daniele Focosi and Mauro Pistello.


View Abstract


Targeting interferon regulatory factor for cardiometabolic diseases: opportunities and challenges


Zhang Yaxing, Zhang Xiao-Jing and Li Hongliang.


View Abstract


Chemokines in the pathogenesis and as therapeutical markers and targets of HCV chronic infection, and HCV extrahepatic manifestations


Poupak Fallahi, Silvia Martina Ferrari, Dilia Giuggioli, Marco Sebastiani, Michele Colaci, Clodoveo Ferri and Alessandro Antonelli.


View Abstract


HDL as a Target for Glycemic Control


Boris Waldman, Alicia J. Jenkins, David Sullivan, Martin K.C. Ng and Anthony C Keech.


View Abstract


VIRTUAL SCREENING FOR THE DEVELOPMENT OF DUAL-INHIBITORS TARGETING TOPOISOMERASE IB AND TYROSYL-DNA PHOSPHODIESTERASE 1


Francesca Cardamone, Simone Pizzi, Federico Iacovelli, Mattia Falconi and Alessandro Desideri.


View Abstract


SIRT1 as a promising novel therapeutic target for myocardial ischemia reperfusion injury and cardiometabolic disease


Dong Han, Jinda Wang, Sai Ma, Yundai Chen and Feng Cao.


View Abstract


Gastric Carcinoma at the Era of Targeted Therapies


Johann DREANIC, Marion DHOOGE, Elena SION, Catherine BREZAULT, Stanislas CHAUSSADE and Romain CORIAT.


View Abstract


Advertisement

Related Journals




Related eBooks


Webmaster Contact: urooj@benthamscience.org Copyright © 2016 Bentham Science