ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)


Volume 15, 10 Issues, 2015


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Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

Aims & ScopeAbstracted/Indexed in

Ranking and Category:
  • 22nd of 58 in Chemistry, Medicinal
  • 85th of 202 in Oncology

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Editor-in-Chief:
Michelle Prudhomme
Universite Blaise Pascal - C.N.R.S
Aubiere Cedex
France


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Current: 2.939
5 - Year: 3.37

Upcoming Articles (E-Pub Abstracts ahead of Print)

A Role for the Inflammatory Mediators Cox-2 and Metalloproteinases in Cancer Stemness
G K Chimal-Ramírez, Na A Espinoza-Sánchez and E M Fuentes-Pananá
View Abstract
In vivo anticancer activity, toxicology and histopathological studies of the thiolate gold(I) complex [Au(Spyrimidine)(PTA-CH2Ph)]Br
Elena García-Moreno, Sonia Gascón, José A. García de Jalón, Mª Jesus Rodriguez-Yoldi, Elena Cerrada and Mariano Laguna
View Abstract
The Use of Anthracyclines for Therapy of CNS Tumors
Martina da Ros, Anna Lisa Iorio, Maurizio Lucchesi, Alessia Stival, Maurizio de Martino and Iacopo Sardi
View Abstract
A Novel Approach to Inhibit Heat Shock Response as Anticancer Strategy by Coumarine Compounds Containing Thiazole Skeleton
İrfan Koca, Mehmet Gümüş, Aykut Özgür, Ali Dişli and Yusuf Tutar
View Abstract
A novel quinolinebased second-generation mTOR inhibitor that induces apoptosis and disruptsPI3K-Akt-mTOR signaling in human leukemia HL-60 cells
Suresh Kumar, Santosh Kumar Guru, Vunnam Venkateswarlu, Fayaz Malik, Ram A. Vishwakarma, Sanghapal D. Sawant and Shashi Bhushan
View Abstract
Anti-Resorptive Drugs and their Impact on Maxillofacial Bone among Cancer Patients
Farzad Borumandi, Tara Aghaloo, Luke Cascarini, Alexander Gaggl and Kunmi Fasanmade
View Abstract
The Applications of Targeting Anti-Cancer Agents in Cancer Therapeutics
Guang-Chun Sun, Xu Yang, Yan Yu and Dai-Wei Zhao
View Abstract
4,6-diaryl pyrimidones as constrained chalcone analogues : Design, Synthesis and Evaluation as antiproliferative agents
Dinesh Kumar, Kunal Nepali, P M S Bedi, Suresh Kumar, Fayaz Malik and Subheet Jain
View Abstract
Effects of Plants and Isolates of Celastraceae Family on Cancer Pathways
Syed Nasir Abbas Bukhari, Ibrahim Jantan and Mohamed Ali Seyed
View Abstract
Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors from the Natural Origin: A Recent Perspective
Harun M. Patel, Rajesh Rane, Neeta Thapliyal, Mahesh Palkar, Mahamadhanif Shaikh and Rajshekhar Karpoormath
View Abstract
Ligustrazine Suppresses the Growth of HRPC Cells through the Inhibition of Cap-Dependent
Jiaoyan Han, Jiao Song, Xiangyun Li, Ming Zhu, Wei Guo, Wei Xing, Rongshen Zhao, Xiao He, Xiaoping Liu, Shali Wang, Yunyun Li, Hong Huang and Xiang Xu
View Abstract
Neddylation Pathway as a Novel Anti-Cancer Target: Mechanistic Investigation and Therapeutic Implication
Yanan Jiang and Lijun Jia
View Abstract
Synthesis of isoxazole moiety containing thieno[2,3-d]pyrimidine derivatives and preliminarily in vitro anticancer activity (Part II)
Jianping Yong, Canzhong Lu and Xiaoyuan Wu
View Abstract
RUNX2 and Osteosarcoma
Na Li, Dongwei Luo, Xiaoxia Hu, Wei Luo, Guanghua Lei, Qian Wang, Ting Zhu, Junxia Gu, Yaojuan Lu and Qiping Zheng
View Abstract
Apigenin and Breast Cancers: from Chemistry to Medicine
Seyed Mohammad Nabavi, Solomon Habtemariam, Maria Daglia and Seyed Fazel Nabavi
View Abstract
Cancer chemoprevention by natural carotenoids as an efficient strategy
Azam Bolhassani
View Abstract
Mouse ATP-binding cassette (ABC) transporters conferring multi-drug resistance
L i Shuaizhang, Wen Zhang, Xuejiao Yin, Shilai Xing, Qunhui Xie, Zhengyu Cao and Bin Zhao
View Abstract
Anti-Cancer Glycosidase Inhibitors from Natural Products: A Computational and Molecular Modelling Perspective
Ashona Singh, Ndumiso Mhlongo and Mahmoud E. S. Soliman
View Abstract
Epoxomicin Sensitizes Resistant Osteosarcoma Cells to TRAIL Induced Apoptosis
Ferhat HANIKOGLU, Aysegul CORT, Hakan OZBEN, Aysegul HANIKOGLU and Tomris OZBEN
View Abstract
Low Concentration of Caffeine Inhibits the Progressionof the Hepatocellular CarcinomaviaAkt Signaling Pathway
Shuying Dong, Jian Kong, Jinge Kong, Qiang Shen, Fandong Kong, Wenbing Sun and Lemin Zheng
View Abstract
Tumorspheres Derived from HCC Cells are Enriched with Cancer Stem Cell-like Cells and Present High Chemoresistance Dependent on the Akt Pathway
Xiao-Li Zhang, Qian Jia, Lin Lv, Tao Deng and Jian Gao
View Abstract
5-Lipoxygenase and Cyclooxygenase inhibitory Dammarane triterpenoid 1 from Borassus flabellifer seed coat, inhibits Tumor Necrosis Factor-α secretion in LPS induced THP-1 human monocytes and induces apoptosis in MIA PaCa-2 Pancreatic cancer cells
Nagendra Sastry Yarla, A Rajaram, Mahaboob Basha, Abdul Rajack, D. S. V. G. K. Kaladhar, Bharat Kumar Allam, Rajeswara Rao, Krishna Nand Singh, K Sunanda Kumari, P Reddanna, Umadevi Parimi, Anupam Bishayee and D Govinda Rao
View Abstract
Is Notch Signaling a Specific Target in Hepatocellular Carcinoma?
Lichun Sun, Guangchun Sun, Yan Yu and David H. Coy
View Abstract
Anticancer Candidates Derived from Natural Cinnamic Acids
Ping Su, Yaling Shi, Jinfeng Wang, Xiuxiu Shen and Jie Zhang
View Abstract
Differential interactions of Cytochrome P450 3A5 and 3A4 with chemotherapeutic agent- vincristine: A comparative molecular dynamics study
Nikhat Saba, Rajabrata Bhuyan, Suman Kumar Nandy and Alpana Seal
View Abstract
Molecular Treatment of Different Breast Cancers
Yanfang Wang, Shousong Cao and Yihui Chen
View Abstract
Quercetin Increase the Chemosensitivity of Breast Cancer Cells to Doxorubicin via PTEN/Akt Pathway
Shi-zheng Li, Shi-feng Qiao, Jun-hua Zhang and Kun Li
View Abstract
Inhibition of testosterone aromatization by the indole-3-carbinol derivative CTet in CYP19A1-overexpressing MCF-7 breast cancer cells
Mauro De Santi, ELISA CARLONI, LUCA GALLUZZI, AURORA DIOTALLEVI, SIMONE LUCARINI, MAURO MAGNANI and GIORGIO BRANDI
View Abstract
Discovery of Novel N-Alkyl 4-Anilinofuro[2,3-b]Quinoline Derivatives (CIL-102 Derivatives) Against Castration-Resistant Human Prostate Cancers
We-Fen Lo, Yu-Wei Chou, Chih-Hua Tseng, Yia-Huei Shiu, Yu-Wen Chen, Shyh-Chyun Yang, Yeh-Long Chen, Ming-Fong Lin and Cherng-Chyi Tzeng
View Abstract
MicroRNAs and Targeted Therapies in Non-Small Cell Lung Cancer: Minireview
Carmelo Tibaldi, Armida D’Incecco and Alessandro Laganà
View Abstract
Liposome Encapsulated All Trans Retinoic Acid (ATRA) has Enhanced Immunomodulatory and Inflammation Reducing Activities in Mice Model
V. M Berlin Grace, Siddikuzzaman and B Rimashree
View Abstract
Curcumin-Based Anti-Prostate Cancer Agents
Qiao-Hong Chen
View Abstract
Molecular Mechanism Behind the Synergistic Activity of Diphenylmethyl Selenocyanate and Cisplatin Against Murine Tumor Model
Pramita Chakraborty, Somnath Singha Roy and Sudin Bhattacharya
View Abstract
Combined Anticancer Therapies: an Overview of the Latest Applications
Maria Teresa Piccolo, Ciro Menale and Stefania Crispi
View Abstract
Exploring Cancer Therapeutics with Natural Products from African Medicinal Plants, Part I: Xanthones, Quinones, Steroids, Coumarins, Phenolics and other Classes of Compounds
Conrad V. Simoben, Akachukwu Ibezim, Fidele Ntie-Kang, Justina N. Nwodo and Lydia L. Lifongo
View Abstract
Current Perspective of Natural Alkaloid Carbazole and its Derivatives as Antitumor Agents
Mahamadhanif S. Shaikh, Neeta Thapliyal, Rajesh A. Rane, Mahesh B. Palkar, A. M. Faya, Harun M. Patel, Wesam S. Alwan, Kavita Jain, Girish A. Hampannavar and Rajshekhar Karpoormath
View Abstract
Acridone-Based Antitumor Agent: A Mini-Review
Wesam S. Alwan, Anand A Mahajan, Rajesh A. Rane, Anish A. Amritkar, Shital S. Naphade, Mayur C. Yerigiri and Rajshekhar Karpoormath
View Abstract
Recent Advances in Drug Development for Squamous Cell Carcinoma
Jun Lei, Bing Fu, Hang Yin, Guanxiu Tang, Shujuan Zhu, Chunli Yan and Quanyong He
View Abstract
A Promising Anti-Cancer and Anti-Oxidant Agents Based on the Pyrrole and Fused Pyrrole: Synthesis, Docking Studies and Biological Evaluation
Samar Said Fatahala, Emad Ahmed Shalaby, Shaymaa Emam Kassab and Mossad Said Mohamed
View Abstract
An Insight into Purine, Tyrosine and Tryptophan Derived Marine Antineoplastic Alkaloids
Mahesh B. Palkar, Rajesh A. Rane, Neeta Thapliyal, Mahamadhanif S Shaikh, Wesam S. Alwan, Kavita S. Jain, Sivanandhan Karunanidhi, Harun M. Patel, Girish A. Hampannavar and Rajshekhar Karpoormath
View Abstract
Recent Trends of Chalconespotentialities as Antiproliferative and Antiresistance Agents
Evelyn Winter, Claudriana Locatelli, Attilio Di Pietro and Tânia B. Creczynski-Pasa
View Abstract
Anticancer Activity of Polyether Ionophore - Salinomycin
Michał Antoszczak and Adam Huczyński
View Abstract
Curcumin as an Adjuvant to Breast Cancer Treatment
Parveen Kumar, Almesh Kadakol, PrashanthKrishna Shasthrula, Nitin Arunrao Mundhe, Vinayak Sudhir Jamdade, Chandana C. Barua and Anil Bhanudas Gaikwad
View Abstract
Coumarin: A Promising Scaffold for Anticancer Agents
Manjinder Kaur, Swarandeep Kohli, Sonali Sandhu, Yogita Bansal and Gulshan Bansal
View Abstract
Berberine exhibits antitumor effects in human ovarian cancer cells
Ping Jin, Chunjie Zhang and Na Li
View Abstract
5-Benzylidene-3,4-dihalo-furan-2-one derivatives inhibit human leukemia cancer cells through suppression of NF-kB and GSK-3β
Fang Wang, Jing Lin, Wen Hou, Mei-Yan Huang, Ping-Hua Sun and Wei-Min Chen
View Abstract
Encouraging microRNA-Based Therapeutic Strategies for Hepatocellular Carcinoma
Min Yao, Li Wang, Liwei Qiu, Qi Qian and Dengfu Yao
View Abstract
A Short Review on the Synthetic Strategies of Duocarmycin Analogs that are Powerful DNA Alkylating Agents
Pravin C. Patil, Vijay Satam and Moses Lee
View Abstract
A Review on the Synthesis and Anti-Cancer Activity of 2-Substituted Quinolines
Kaalin Gopaul, Suhas A. Shintre and Neil A. Koorbanally
View Abstract
Design and Synthesis of Novel Antineoplastic Agents Inspired from Marine Bromopyrrole Alkaloids
Rajesh A. Rane, Pavan Kumar Bangalore, Shital S. Naphade, Harun M. Patel, Mahesh B. Palkar and Rajshekhar Karpoormath
View Abstract
Synthesis of Novel Amides Based on Acridone Scaffold with Interesting Antineoplastic Activity
Anand A Mahajan, Rajesh A. Rane, Anish A. Amritkar, Shital S. Naphade, Pankaj B. Miniyar, Pavan Kumar Bangalore and Rajshekhar Karpoormath
View Abstract
Recent Developments Towards Podophyllotoxin Congeners as Potential Apoptosis Inducers
Ahmed Kamal, Syed Mohammed Ali Hussaini and M. Shaheer Malik
View Abstract
Recent Advances of Natural and Synthetic β-Carbolines as Anticancer Agents
Mingming Zhang and Dianqing Sun
View Abstract
Ozone Dosage Effect on C6 Cell Growth: in Vitro and in Vivo Tests
Arizbeth Pérez, Clara L. Santos Cuevas, Isaac Chairez, Tatyana Poznyak, David Ordaz-Rosado, Rocío García-Becerra and Mario E. Romero Piña
View Abstract
Different 6-Aryl-Fulvenes exert anti-proliferative effects on Cancer Cells
Esther Sirignano, Assunta Pisano, Anna Caruso, Carmela Saturnino, Maria Stefania Sinicropi, Rosamaria Lappano, Antonio Botta, Domenico Iacopetta, Marcello Maggiolini and Pasquale Longo
View Abstract
Effect of two Antiandrogens as Protectors of Prostate and Brain in a Huntington´s Animal Model
David Calderón Guzmán, Eugene Bratoeff, Alejandra Chávez Riveros, Norma Osnaya Brizuela, Gerardo Barragán Mejía, Ernestina Hernández García, Hugo Juárez Olguín and Edna García Crúz
View Abstract
A small-molecule inhibitor, 5'-O-tritylthymidine, targets FAK and Mdm-2 interaction, and blocks breast and colon tumorigenesis in vivo.
V M Golubovskaya, N L Palma, M Zheng, B Ho, A Magis, D Ostrov and WG Cance
View Abstract
Mitoxantrone Targets The ATP-Binding Site Of FAK, Binds The FAK Kinase Domain And Decreases FAK, Pyk-2, C-Src, And IGF-1R, In Vitro Kinase Activities
Vita Golubovskaya, Baotran Ho, Min Zheng, Andrew Magis, David Ostrov and William Cance
View Abstract
Recent advance in the studies of Beta-glucans for cancer therapy

View Abstract
Epigenetic Mechanisms Underlying Diet-Sourced Compounds in the Prevention and Treatment of Gastrointestinal Cancer
Rebecca W. Knackstedt, Vondina R. Moseley and Michael J. Wargovich
View Abstract
The Effects of β-glucans on Cancer Metastasis
Taek J. Yoon, Sushruta Koppula and Kwang H. Lee
View Abstract
Vitamin D and Breast Cancer Incidence and Outcome
Jianghua Liu, Deliang Cao and Rowan T. Chlebowski
View Abstract
Vitamin D, Sunlight, and the Epidemiology of Prostate Cancer
Gary G. Schwartz
View Abstract
Supplementation, Optimal Status, and Analytical Determination of Vitamin D: Where are we standing in 2012?
Jean-Claude Souberbielle and Etienne Cavalier
View Abstract
Role of Calcium, Vitamin D, and the Extrarenal Vitamin D Hydroxylases during Carcinogenesis
Julia Höbaus, Ursula Thiem, Doris M. Hummel and Enikö Kallay
View Abstract
Epidemiology of Vitamin D And Colorectal Cancer
Jianghua Liu, Deliang Cao and Edward Giovannucci
View Abstract
Recombinant Snake Venom Cystatin Inhibits Tumor Angiogenesis in vitro and in vivo Associated with Downregulation
Qun Xie, Nanhong Tang, Rong Wan, Yuanlin Qi, Xu Lin and Jianyin Lin
View Abstract
SJSZ glycoprotein (38 kDa) inhibits cell cycle and oxidative stress in N- Methyl-N`-nitro-N-nitrosoguanidine-induced ICR mice
Jin Lee and Kye-Taek Lim
View Abstract
N6-Isopentenyladenosine and its Analogue N6-Benzyladenosine Induce Cell Cycle Arrest and Apoptosis in Bladder
Sara Castiglioni, Silvana Casati, Roberta Ottria, Pierangela Ciuffreda and Jeanette A. M. Maier
View Abstract
Biology and Medicinal Chemistry Approaches towards Various Apoptosis Inducers
Vivek K. Vyas, Chetan Chintha and Mitul R. Pandya
View Abstract
Synthesis and Antimicrobial Activity of Nitroalkenyl Arenes
Gina Nicoletti
View Abstract
Carbon Nanotubes in The Diagnosis and Treatment of Malignant Melanoma
Naghmeh Naderi, Seyed Yazdan Madani, Afshin Mosahebi and Alexander M. Seifalian
View Abstract
Plant-Derived Secondary Metabolites as Anticancer Agents
Diwan S. Rawat and Ram Singh
View Abstract
Cytoskeletal Alterations That Confer Resistance to Anti-Tubulin Chemotherapeutics
Arun Kanakkanthara, Paul H. Teesdale-Spittle and John H. Miller
View Abstract
Editorial: Survival Signaling through Focal Adhesion Kinase in Tumors
Vita Golubovskaya
View Abstract
The Effects of β-Glucans on Dendritic Cells and Implications for Cancer Therapy
Sabrin Husein Albeituni and Jun Yan
View Abstract
Editorial:Cytochrome P450 for cancer prevention and therapy
Tai C. Chen
View Abstract
β-Glucans and their Applications in Cancer Therapy: Focus on Human Studies
Eiman Aleem
View Abstract
Antitumoral activity of indole-3-carbinol cyclic tri- and tetrameric derivatives mixture in human breast cancer cells: in vitro and in vivo studies.
Giorgio Brandi, Alessandra Fraternale, Simone Lucarini, Mirko Paiardini, Mauro De Santi, Barbara Cervasi, Maria Filomena Paoletti, Luca Galluzzi, Andrea Duranti and Mauro Magnani
View Abstract
Integrated Therapeutic Approaches in the Treatment of Human Cancer
Francesco Caponigro
View Abstract
Cytotoxicity and cell death mechanisms induced by a Novel Bisnaphthalimidopropyl Derivative against the NCI-H460
Raquel T. Lima, Gemma A. Barron, Joanna A. Grabowska, Giovanna Bermano, Simranjeet Kaur, Nilanjan Roy, M. Helena Vasconcelos and Paul Kong Thoo Lin
View Abstract
Inhibition of PI3K/Akt/mTOR Signaling by Natural Products
Shile Huang
View Abstract
Vitamin D supplementation and cancer: review of randomized controlled trials
Matteo Lazzeroni, Davide Serrano, Stefan Pilz and Sara Gandini
View Abstract
Vitamin D and cancer mortality: systematic review of prospective epidemiological studies
Stefan Pilz, Katharina Kienreich, Andreas Tomaschitz, Eberhard Ritz, Elisabeth Lerchbaum, Barbara Obermayer-Pietsch, Veronika Matzi, Joerg Lindenmann, Winfried März, Sara Gandini and Jacqueline M. Dekker
View Abstract
Update on evidence that support a role of solar ultraviolet-B irradiance in reducing cancer risk
William B. Grant
View Abstract
The anti-cancer actions of vitamin D
Kun-Chun Chiang and Tai C. Chen
View Abstract
Sunlight Vitamin D and Skin Cancer
Rebecca S. Mason and Jörg Reichrath
View Abstract
Vitamin D, Sunlight and Cancer Connection
Michael F. Holick
View Abstract
Shedding Light on Serum Vitamin D Concentrations and the Risk of Rarer Cancers
Kathy J. Helzlsouer and Lisa Gallicchio
View Abstract
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