ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)


Volume 16, 12 Issues, 2016


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Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

Aims & ScopeAbstracted/Indexed in

Ranking and Category:
  • 27th of 59 in Chemistry, Medicinal

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Editor-in-Chief:
Michelle Prudhomme
Universite Blaise Pascal - C.N.R.S
Aubiere Cedex
France


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Current: 2.722
5 - Year: 2.849

Upcoming Articles (E-Pub Abstracts ahead of Print)

Ester of Quinoxaline-7-carboxylate 1,4-di-N-oxide as Apoptosis Inductors in K-562 Cell Line: An in vitro, QSAR and DFT study


Gildardo Rivera-Sánchez, Sergio Andrade-Ochoa, Manolo S. Ortega Romero, Isidro Palos, Antonio Monge and Luvia Enid Sánchez-Torres.


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Synthesis, Molecular Docking Study and in vitro Anticancer Activity of Tetrazole Linked Benzochromene Derivatives


Sridevi Gorle, Suresh Maddila, Surya N. Maddila, Kovashnee Naicker, Moganavelli Singh, Parvesh Singh and Sreekantha B Jonnalagadda.


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Killing Glioma ‘Stem-like’ Cells via Drug-Induced Relocation of Endosomal Urokinase Proteins


Fredric A. Gorin, Nagarekha Pasupuleti, Dinesh Mahajan and Sundeep Dugar.


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1,3,4-Thiadiazole based anticancer agents


Alireza Aliabadi.


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Glucose Oncometabolism of Esophageal Cancer


Jason S. Hochwald and Jianliang Zhang.


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Phytochemical Analysis with Antioxidant and Cytotoxicity Studies of the Bioactive Principles from Zanthoxylum Capense (Small Knobwood)


Olusola Bodede, Shakira Shaik, Moganavelli Singh and Roshila Moodley.


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Construction of An Anticancer Fusion Peptide (ACFP) Derived from Milk Proteins and An Assay of Anti-ovarian Cancer Cells in vitro


Yide Qin, Juan Zhou, Wenxiao Zhang, Xue Yang, Jing Wang, Cai Wei, Fang Gu and Ting Lei.


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Statins and Alkylphospholipids as New Anticancer Agents Targeting Lipid Metabolism


Sonia Apostolova, Reneta Toshkova, Albena Momchilova and Rumiana Tzoneva.


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Induction of Autophagic Cell Death In Apoptosis-Resistant Pancreatic Cancer Cells Using Benzo[α]Phenoxazines Derivatives, 10-Methyl-Benzo[α]Phenoxazine-5-One And Benzo[α]Phenoxazine-5-One


Sanjima Pal, Sunita Salunke-Gawali and V Badireenath Konkimalla.


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Pyrrolidino Analogues of Gefitinib with Improved EGFR Inhibition, Cancer Cell Cytotoxicity and Pharmacokinetic Properties


JingKun Fang, Zhimin Xu, Yingjun Zhang, Weihong Zhang, Bing Liu, Tengxiao Sun and Yu Fang.


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Glycodendrimer PPI as a Potential Drug in Chronic Lymphocytic Leukemia. The Influence of Glycodendrimer on Apoptosis in in vitro B-CLL Cells Defined by Microarrays


Ida Franiak-Pietryga, Ewelina Ziółkowska, Barbara Ziemba, Dietmar Appelhans, Brigitte Voit, Aleksandra Kaczmarek, Tadeusz Robak, Barbara Klajnert-Maculewicz, Barbara Cebula-Obrzut, Piotr Smolewski, Maciej Borowiec and Maria Bryszewska.


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Ruthenium(II) Complexes as Potential Apoptosis Inducers in Chemotherapy


Kangdi Zheng, Qiong Wu, Chengxi Wang, Weijun Tan and Wenjie Mei.


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A Facile and Microwave-assisted Rapid Synthesis of 2-Arylamino-4-(3c-indolyl)-thiazoles as Apoptosis Inducing Cytotoxic Agents


Dalip Kumar, Mukund P. Tantak, Dipanwita Das Mukherjee, Anil Kumar and Gopal Chakrabarti.


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Quinoxaline Nucleus: A Promising Scaffold in Anti-cancer Drug Discovery


Alessandra Campbell Pinheiro, Thais Cristina Mendonça Nogueira and Marcus Vinícius Nora de Souza.


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Physico-chemical and biological evaluation of flavonols: fisetin, quercetin and kaempferol alone and incorporated in beta cyclodextrins


Corina Danciu, Florina Bojin, Rita Ambrus, Delia Muntean, Codruta Soica, Virgil Paunescu, Mirabela Cristea, Iulia Pinzaru and Cristina Dehelean.


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Retinoic acid Signaling in P19 Stem Cell Differentiation


Jyotshna Kanungo.


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Synthesis, in vitro antiproliferative and antiinflammatory activities, and kinase inhibitory effects of a new series of 1,3,4-triarylpyrazole derivatives


Mohammed El-Gamal.


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Hydroxy cinnamic acid derivatives as partial PPARγ agonists: In silico studies, synthesis and biological characterization against chronic myeloid leukemia cell line (K-562)


Hardik Joshi, Kavita Marulkar, Vikram Gota and CS Ramaa.


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Sodium Selenite as an Anti-Cancer Agent


Boguslaw Lipinski.


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Diazenyl derivatives and their Complexes as Anticancer Agents


Harmeet Kaur, Snehlata Yadav and Balasubramanian Narasimhan.


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Mutant B-Raf Kinase inhibitors as anticancer agents


VIVEK ASATI, Sanjay Kumar Bharti and DEBARSHI KAR MAHAPATRA.


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Cordycepin Affects Multiple Apoptotic Pathways to Mediate Hepatocellular Carcinoma Cell Death


Yulin Zhou, Zhihua Guo, Qingfan Meng, Jiahui Lu, Ning Wang, Hui Liu, Qiming Liang, Yutong Quan, Di Wang and Jing Xie.


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Rapamycin-loaded immunoliposomes functionalized with trastuzumab: a strategy to enhance cytotoxicity to HER2-positive breast cancer cells


Josimar O. Eloy, Raquel Petrilli, Robert W. Brueggemeier, Juliana Maldonado Marchetti and Robert J Lee.


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Preparation and evaluation of in vitro self-assembling HSA nanoparticles for cabazitaxel


Na Qu, Yating Sun, Jing Xie and Lesheng Teng.


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Effect of PUFAs oral administration on the amount of Apoptotic Caspases Enzymes in gastric cancer patients undergoing chemotherapy


Homayun Dolatkhah, Ahmad Movahedian, Mohammad-Hossein Somi, Mahmud Aghaei, Naser Samadi, Ahmad Mirza-Aghazade and Ali Esfahani.


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Use of azoles containing natural products in cancer prevention and treatment: An overview


Nasimudeen R. Jabir, Chelapram K. Firoz, Ashish Bhushan, Shams Tabrez and Mohammad A Kamal.


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Exploring the binding affinity of novel syringic acid analogues and critical determinants of selectivity as potent proteasome inhibitors


Srinivasulu Cheemanapalli, CM Anuradha, P Madhusudhana, M Mahesh, Pongali B Raghavendra and Chitta Suresh Kumar.


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Copper(II) complexes with saccharinate and glutamate as antitumor agents. Cyto- and genotoxicity in human osteosarcoma cells


J.F. Cadavid-Vargas, I.E. León, S.B. Etcheverry, E. Santi, M.H. Torre and AL Di Virgilio.


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New poly(3-hydroxybutyrate) microparticles with paclitaxel sustained release for intraperitoneal administration


A.P. Bonartsev, A.L. Zernov, S.G. Yakovlev, I.I. Zharkova, V.L. Myshkina, T.K. Mahina, G.A. Bonartseva, N.V. Andronova, G.B. Smirnova, J.A. Borisova, M.S. Kalishjan, K.V. Shaitan and HM Treshalina.


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Lichen acids may be used as a potential drug for cancer therapy; by inhibiting mitochondrial thioredoxin reductase purified from rat lung


Ilknur Ozgencli, Harun Budak, Mehmet Ciftci and Mustafa Anar.


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Synthesis and Anticancer Study of novel 4H-Chromen Derivatives


Xiaolin Lu, Gaochao Dong, Ying Zheng, Chao Zhang, Yang Qiu, Tao Lu and Xiang Zhou.


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Novel 2-Thienyl- and 2-Benzothienyl-Substituted 6-(2-Imidazolinyl)Benzothiazoles: Synthesis; in vitro Evaluation of Antitumor Effects and Assessment of Mitochondrial Toxicity


Livio Racané, Mirela Sedić, Nataša Ilić, Maja Aleksić, Sandra Kraljević Pavelić and Grace Karminski-Zamola.


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Aryl maleimides as apoptosis inducers on L5178-Y murine leukemia cells (in silico, in vitro and ex vivo study)


Erik Andrade-Jorge, Marycarmen Godínez-Victoria, Luvia Enid Sánchez-Torres, Luis Humberto Fabila-Castillo and José G Trujillo-Ferrara.


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Design, synthesis and evaluation of 5-pyridin-4-yl-2-thioxo-[1,3,4]oxadiazol-3-yl derivatives as anti-angiogenic agents Targeting VEGFR-2.


Umesh Bhanushali, Samidha Kalekar-Joshi, Renuka Kulkarni-Munshi, Swapna Yellanki, Raghavender Medishetty, Pushkar Kulkarni and C S Ramaa.


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Thiazolidinone constraint combretastatin analogs as novel antitubulin agents: Design, synthesis, biological evaluation and docking studies


Sahil Sharma, Manish Kumar Gupta, Ajit Kumar Saxena and Preet Mohinder Singh Bedi.


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Epidrugs in the immunotherapy of cutaneous and uveal melanoma


Mario Venza, Maria Visalli, Teresa Catalano, Concetta Beninati, Diana Teti and Isabella Venza.


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Epigenetic and miRNAs dysregulation in prostate cancer: the role of nutraceuticals


Alessandra Bosutti, Fabrizio Zanconati, Gabriele Grassi, Barbara Dapas, Sabina Passamonti and Bruna Scaggiante.


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Trans-platinum(II)/(IV) complexes with acetylpyridine ligands as antivascular agents in vitro: cytotoxic and antiangiogenic potential


Filipović Lana, Aranđelović Sandra, Krivokuća Ana, Janković Radmila, Dojčinović Biljana and Radulović Siniša.


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Melatonin regulates angiogenic and inflammatory proteins in MDA-MB-231 cell line and in co-culture with cancer-associated fibroblasts


Larissa Bazela Maschio-Signorini, Gabriela Bottaro Gelaleti, Marina Gobbe Moschetta, Thaiz Ferraz Borin, Bruna Victorasso Jardim-Perassi, Juliana Ramos Lopes, Jéssica Zani Lacerda, Rosimeire Aparecida Roela, Newton Antonio Bordin Júnior, Lizandra Akina Corrêa, Jessica Picinin Cardoso and Debora Aparecida Pires de Campos Zuccari.


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To Analyze the Amelioration of Phenobarbital Induced Oxidative Stress by Erucin, as Indicated by Biochemical and Histological Alterations


Rohit Arora, Sakshi Bhushan, Rakesh Kumar, Rahul Mannan, Pardeep Kaur, Bikram Singh, Ritika Sharma, Adarsh Pal Vig, Balbir Singh, Amrit Pal Singh and Saroj Arora.


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4-Anilinoquinazoline Derivatives with Epidermal Growth Factor Receptor Inhibitor Activity


Fang Liu, Yinjiu Huang, Hao Liu, Leina Li, Gang Liu, Yun Cheng, Yan Xu and Wenwen Chen.


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Brain-metastatic breast cancer: clinical considerations and pharmacological approaches


Ana Carolina Andrade, Daniel Sartori Ferruzzi and Carolina Panis.


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Anticancer drug combinations, how far we can go through?


Da-Yong Lu, En-Hong Chen, Hong-Ying Wu, Ting-Ren Lu, Bin Xu and Jian Ding.


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Differential Cytotoxicity, Cellular Uptake, Apoptosis and Inhibition of BRCA1 Expression of BRCA1-Defective and Sporadic Breast Cancer Cells Induced by an Anticancer Ruthenium(II)-Arene Compound, RAPTA-EA1


Adisorn Ratanaphan, Tidarat Nhukeaw, Khwanjira Hongthong and Paul J Dyson.


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Effects of Epirubicin and Cisplatin against 4T1 Breast Cancer Cells are Enhanced by Myrtucommulone-A


Kenan izgi, Banu iskender, Cagri Sakalar, Aslıhan Arslanhan, Esra Hilal Yüksek, Esra Hizar and Halit Canatan.


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Synthesis and in vitro evaluation of the anticancer potential of new aminoalkanol derivatives of xanthone


Natalia Szkaradek, Daniel Sypniewski, Anna M. Waszkielewicz, Agnieszka Gunia-Krzyżak, Anna Galilejczyk, Sabina Gałka, Henryk Marona and Ilona Bednarek.


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Inhibitors of Cancer Stem Cells


María E. García-Rubiño, César Lozano-López and Joaquín M Campos.


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Circulating tumor cells: a new window for diagnosis and evaluation of cancer


Meihui Liu, Min Tang, Ming Li, Feng Gao, Can Shi, Jing Hou and Wenbin Zeng.


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Review Article: Novel Therapeutic Strategies Against Cancer: Marine-derived Drugs May Be The Answer?


Maria Alessandra Gammone, Graziano Riccioni, Fabio Galvano and Nicolantonio D'Orazio.


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Molecular Mechanisms of Anti-cancer Activities of β-elemene: Targeting Hallmarks of Cancer


Shiyu Jiang, Chunhua Ling, Wei Li, Hongxin Jiang, Qiaoming Zhi and Min Jiang.


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Peroxisome Proliferator-activated Receptors and their ligands in cancer drug resistance: opportunity or challenge


Bahman Yousefi, Nosratollah Zarghami, Nasser Samadi and Maryam Majidinia.


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8-bromo-7-methoxychrysin reversed M2 polarization of tumor-associated macrophages induced by liver cancer stem-like cells


Shuwen Sun, Yinghong Cui, Kaiqun Ren, Meifang Quan, Zhenwei Song, Hui Zou, Duo Li, Yu Zheng and Jianguo Cao.


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Natural Product-Derived Spirooxindole Fragments Serve as Privileged Substructures for Discovery of New Anticancer Agents


Bin Yu, Yi-Chao Zheng, Xiao-Jing Shi, Ping-Ping Qi and Hong-Min Liu.


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Lgr5 contributes to intestinal metaplasia during gastric carcinogenesis: a meta-analysis


Ye Han, Hugang Shen, Xiaofeng Xue, Bin Yuan, Yuting Kuang, Qiaoming Zhi and Hong Zhao.


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A Novel Method to Synthesize 4-Aryl-1H-1,2,3-Triazoles and their Anti-hepatoma Activity


Xiaolong Li, Yun He, Li Hai, Tao Zhang and Yong Wu.


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Long noncoding RNA C21orF96 promotes the migration, invasion and lymph node metastasis in gastric cancer


Ziguo Yang, Qiaoming Zhi, Dan Wang, Li Zhang, Yuting Kuang, Ruizhen Miao, Yulong Shi and Xiaobo Guo.


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Hepato and Cardiotoxicity of Chemotherapeutic Treatment Evaluated by Means of Small Animal Imaging.


Fiorella Carla Tesán, Mariano Portillo, Diego Martinel-Lamas, Vanina Araceli Medina, María Jimena Salgueiro and Marcela Zubillaga.


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Nano-Hydroxyapatite Doped with Ho-166 as Drug Delivery System for Bone Cancer Therapy


Franciana Maria Rosa da Silva, Julio Cezar de Almeida Junior, Elizabeth Eugênio de Mello Oliveira, Marta de Souza Albernaz, Alexandre Malta Rossi and Ralph Santos-Oliveira.


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PERSPECTIVES OF BENZIMIDAZOLE DERIVATIVES AS ANTICANCER AGENTS IN THE NEW ERA


Snehlata Yadav, Balasubramanian Narasimhan and Harmeet kaur.


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Biological Potential of Halfsandwich Ruthenium(II) and Iridium(III) Complexes


Gerd Ludwig, Marija Mojić, Mirna Z. Bulatović, Sanja Mijatović, Danijela Maksimović-Ivanić, Dirk Steinborn and Goran N Kaluđerović.


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15,16-dihydrotanshinone I induces apoptosis and inhibits the proliferation, migration of human osteosarcoma cell line 143B in vitro


Xuepeng Chen, Qihong Li, Yan He, Hongjiang Du, Zhajun Zhan, Hong zhao, Jiejun Shi, Qingsong Ye and Ji'an Hu.


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Flavonoids with Therapeutic Potential in Prostate Cancer


Bao Vue, Sheng Zhang and Qiao-Hong Chen.


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Research Progress on the Antitumor Effects of Rhein: Literature Review


Chao Wu, Hongyan Cao, Hua Zhou, Lin Sun, Jingui Xue, Jianyuan Li, Yanqin Bian, Runfei Sun, Shu Dong, Ping Liu and Mingyu Sun.


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1, 3, 6-Trihydroxy-7-methyl-9, 10-anthracenedione isolated from genus Lindera with anti-cancer activity


Guoqing Wei, Hui Chen, Fangyuan Nie, Xiaofeng Ma and Hezhong Jiang.


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O-6-methylguanine-DNA Methyltransferase Inhibits Gastric Carcinoma Cell Migration and Invasion by Downregulation of Matrix Metalloproteinase 2


Chenglong Li, Li Deng, Qiaoming Zhi, Qingyou Meng, Aimin Qian, Hongfei Sang, Jiazeng Xia and Xiaoqiang Li.


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Synthesis of Diflunisal thiazolidinones as anticancer agents


Sevil Şenkardeş, Özlem Bingöl Özakpınar, Derya Özsavcı, Azize Şener, Özge Çevik and ŞGüniz Küçükgüzel.


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Up-regulated circulating miR-106a by DNA methylation promised a potential diagnostic and prognostic marker for gastric cancer


Renshun Yuan, Gang Wang, Qiaoming Zhi, Huabin Chen, Ye Han, Bin Wang, Zhongyang Kou, Hao Hu, Zhaoji Guo, Xiaofeng Xue and Hong Zhao.


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