ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)

Volume 14, 10 Issues, 2014

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Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

Aims & ScopeAbstracted/Indexed in

Ranking and Category:
  • 22nd of 58 in Chemistry, Medicinal
  • 85th of 202 in Oncology

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Michelle Prudhomme
Universite Blaise Pascal - C.N.R.S
Aubiere Cedex

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Upcoming Articles (E-Pub Abstracts ahead of Print)

Effectiveness of Two Novel Anionic and Cationic Platinum Complexes in the Treatment of Osteosarcoma
Kentaro Igarashi, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Akira Odani and Hiroyuki Tsuchiya
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Synthesis and Anticancer Activity Evaluation of Some Benzothiazole-Piperazine Derivatives
Enise Ece Gurdal, Ebru Buclulgan, Irem Durmaz, Rengul Cetin-Atalay and Mine Yarim
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Targeting Mitochondrial Citrate Transport in Breast Cancer Cell Lines
Ali Burak Ozkaya, A k Handan, Sevcan Atay and Hikmet Hakan Aydin
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Encouraging microRNA-Based Therapeutic Strategies for Hepatocellular Carcinoma
Min Yao, Li Wang, Liwei Qiu, Qi Qian and Dengfu Yao
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Lessons from Nature: Sources and Strategies for Developing AMPK Activators for Cancer Chemotherapeutics
Richard T. Arkwright, Rahul Deshmukh, Nikhil Adapa, Ryan Stevens, Emily Zonder, Zhongyu Zhang, Pershang Farshi, Reda Saber Ibrahim Ahmed, Hossny Awad El-Banna, Tak-Hang Chan and Q. Ping Dou
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A Short Review on the Synthetic Strategies of Duocarmycin Analogs that are Powerful DNA Alkylating Agents
Pravin C. Patil, Vijay Satam and Moses Lee
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A Review on the Synthesis and Anti-Cancer Activity of 2-Substituted Quinolines
Kaalin Gopaul, Suhas A. Shintre and Neil A. Koorbanally
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Small Molecules for Immunomodulation in Cancer
Vidhya V. Iyer
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Design and Synthesis of Novel Antineoplastic Agents Inspired from Marine Bromopyrrole Alkaloids
Rajesh A. Rane, Pavan Kumar Bangalore, Shital S. Naphade, Harun M. Patel, Mahesh B. Palkar and Rajshekhar Karpoormath
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Gold Nanoparticle - Lignan Complexes Inhibited Mcf-7 Cell Proliferation In Vitro : A Novel Conjugation For Cancer Therapy
Filiz Bakar, Mehmet G. Caglayan, Feyyaz Onur, Serpil Nebioglu and Ismail M. Palabiyik
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Dual Induction of Mitochondrial Apoptosis and Senescence in Chronic Myelogenous Leukemia by Myrtucommulone A
Cindy Grandjenette, Michael Schnekenburger, Franck Morceau, Fabienne Mack, Katja Wiechmann, Oliver Werz, Mario Dicato and Marc Diederich
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Synthesis of Novel Amides Based on Acridone Scaffold with Interesting Antineoplastic Activity
Anand A Mahajan, Rajesh A. Rane, Anish A. Amritkar, Shital S. Naphade, Pankaj B. Miniyar, Pavan Kumar Bangalore and Rajshekhar Karpoormath
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Recent Developments Towards Podophyllotoxin Congeners as Potential Apoptosis Inducers
Ahmed Kamal, Syed Mohammed Ali Hussaini and M. Shaheer Malik
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Isothiouronium Salts Reduce NRAS Expression, Induce Apoptosis and Decrease Invasion of Melanoma Cells
Júlia Cisilotto, Misael Ferreira, Fabíola Branco Filippin-Monteiro, Adailton João Bortoluzzi, Marcus Mandolesi and Tânia Beatriz Creczynski-Pasa
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Recent Advances of Natural and Synthetic β-Carbolines as Anticancer Agents
Mingming Zhang and Dianqing Sun
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Poly(ethylene glycol) Amphiphilic Copolymer for Anticancer Drugs Delivery
Runliang Feng, Wenxia Zhu, Fangfang Teng, Na Liu, Fengying Yang, Ning Meng and Zhimei Song
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Cystine Dimethyl Ester Induces Apoptosis Through The Regulation of PKC-δ and PKC-ε in Prostate Cancer Cells
Nilgun Gurbuz, Margaret A. Park, Paul Dent, Asim B. Abdel Mageed, Suresh C. Sikka and Asli Baykal
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Identification and characterization of the biosynthetic gene cluster of thiolutin, a tumor angiogenesis inhibitor, in Saccharothrix algeriensis NRRL B-24137
Sheng Huang, Ming Him Tong, Zhiwei Qin, Zixin Deng, Hai Deng and Yi Yu
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Marizomib, a potent second generation proteasome inhibitor from natural origin
Long Ma and Aipo Diao
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Review of Procedures Used for the Extraction of Anti-Cancer Compounds from Tropical Plants
Saurabh Pandey, Paul N. Shaw and Amitha K. Hewavitharana
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Synthesis of Nitroaromatic Compounds as Potential Anticancer Agents
Marcela Silva Lopes, Camila Filizzola de Andrade Sena, Bruno Leonardo Silva, Cristina Maria de Souza, Jonas Pereira Ramos, Geovanni Dantas Cassali, Elaine Maria de Souza-Fagundes, Ricardo José Alves, Mônica Cristina de Oliveira and Renata Barbosa de Oliveira
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The Cytotoxic and Mechanistic Effects of Aaptamine on Hepatocellular Carcinoma
Qiao-lu Li, Ping-ping Zhang, Pei-qin Wang, Hao-bing Yu, Wen-zheng Hu, Wen-hui Wu, Shun-shen Chen, Xin Zhang, Fei Chen, Jun-ping Zhang, Zhi-yong Chu and Hou-wen Lin
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PreQ0 Base, an Unusual Metabolite with Anti-cancer Activity from Streptomyces Qinglanensis 172205
Dongbo Xu, Min Ma, Yongfeng Liu, Ting Zhou, Kexin Wang, Zixin Deng and Kui Hong
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Ozone Dosage Effect on C6 Cell Growth: in Vitro and in Vivo Tests
Arizbeth Pérez, Clara L. Santos Cuevas, Isaac Chairez, Tatyana Poznyak, David Ordaz-Rosado, Rocío García-Becerra and Mario E. Romero Piña
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Toxic effects of Aflatoxin B1 on embryonic development of zebrafish (Danio rerio): Potential activity of Piceatannol encapsulated Chitosan/poly (lactic acid) nanoparticles
D Jeevitha, B R Malathy and B Santhosh Kumar
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Different 6-Aryl-Fulvenes exert anti-proliferative effects on Cancer Cells
Esther Sirignano, Assunta Pisano, Anna Caruso, Carmela Saturnino, Maria Stefania Sinicropi, Rosamaria Lappano, Antonio Botta, Domenico Iacopetta, Marcello Maggiolini and Pasquale Longo
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Effect of two Antiandrogens as Protectors of Prostate and Brain in a Huntington´s Animal Model
David Calderón Guzmán, Eugene Bratoeff, Alejandra Chávez Riveros, Norma Osnaya Brizuela, Gerardo Barragán Mejía, Ernestina Hernández García, Hugo Juárez Olguín and Edna García Crúz
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HUHS1015 Induces Necroptosis and Caspase-Independent Apoptosis of MKN28 Human Gastric Cancer Cells in Association with AMID Accumulation in the Nucleus
Yoshiko Kaku, Ayako Tsuchiya, Takeshi Kanno and Tomoyuki Nishizaki
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A small-molecule inhibitor, 5'-O-tritylthymidine, targets FAK and Mdm-2 interaction, and blocks breast and colon tumorigenesis in vivo.
V M Golubovskaya, N L Palma, M Zheng, B Ho, A Magis, D Ostrov and WG Cance
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Mitoxantrone Targets The ATP-Binding Site Of FAK, Binds The FAK Kinase Domain And Decreases FAK, Pyk-2, C-Src, And IGF-1R, In Vitro Kinase Activities
Vita Golubovskaya, Baotran Ho, Min Zheng, Andrew Magis, David Ostrov and William Cance
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Recent advance in the studies of Beta-glucans for cancer therapy

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Epigenetic Mechanisms Underlying Diet-Sourced Compounds in the Prevention and Treatment of Gastrointestinal Cancer
Rebecca W. Knackstedt, Vondina R. Moseley and Michael J. Wargovich
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Mesenchymal Stromal Cells Uptake And Release Paclitaxel Without Reducing Its Anticancer Activity
Massimo Mariotti, Renato Colognato, Marco Rimoldi, Manuela Rizzetto, Francesca Sisto, Valentina Cocce, Arianna Bonomi, Eugenio Parati, Giulio Alessandri, Renzo Bagnati and Augusto Pessina
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Anti-Proliferative Activities of Terpenoids Isolated from Alisma Orientalis and their Structure-Activity Relationships
Wen Xu, Ting Li, Jian-Fang Qiu, Shui-Sheng Wu, Ming-Qing Huang, Gen-Li Lin, Qing-Wen Zhang, Xiu-Ping Chen and Jin-Jian Lu
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Recent Developments on Thiourea Based Anticancer Chemotherapeutics
Vikas Kumar and Swapandeep Singh Chimni
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The Effects of β-glucans on Cancer Metastasis
Taek J. Yoon, Sushruta Koppula and Kwang H. Lee
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Vitamin D and Breast Cancer Incidence and Outcome
Jianghua Liu, Deliang Cao and Rowan T. Chlebowski
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Vitamin D, Sunlight, and the Epidemiology of Prostate Cancer
Gary G. Schwartz
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Supplementation, Optimal Status, and Analytical Determination of Vitamin D: Where are we standing in 2012?
Jean-Claude Souberbielle and Etienne Cavalier
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Role of Calcium, Vitamin D, and the Extrarenal Vitamin D Hydroxylases during Carcinogenesis
Julia Höbaus, Ursula Thiem, Doris M. Hummel and Enikö Kallay
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Epidemiology of Vitamin D And Colorectal Cancer
Jianghua Liu, Deliang Cao and Edward Giovannucci
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Recombinant Snake Venom Cystatin Inhibits Tumor Angiogenesis in vitro and in vivo Associated with Downregulation
Qun Xie, Nanhong Tang, Rong Wan, Yuanlin Qi, Xu Lin and Jianyin Lin
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SJSZ glycoprotein (38 kDa) inhibits cell cycle and oxidative stress in N- Methyl-N`-nitro-N-nitrosoguanidine-induced ICR mice
Jin Lee and Kye-Taek Lim
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N6-Isopentenyladenosine and its Analogue N6-Benzyladenosine Induce Cell Cycle Arrest and Apoptosis in Bladder
Sara Castiglioni, Silvana Casati, Roberta Ottria, Pierangela Ciuffreda and Jeanette A. M. Maier
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Biology and Medicinal Chemistry Approaches towards Various Apoptosis Inducers
Vivek K. Vyas, Chetan Chintha and Mitul R. Pandya
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Synthesis and Antimicrobial Activity of Nitroalkenyl Arenes
Gina Nicoletti
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Carbon Nanotubes in The Diagnosis and Treatment of Malignant Melanoma
Naghmeh Naderi, Seyed Yazdan Madani, Afshin Mosahebi and Alexander M. Seifalian
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Plant-Derived Secondary Metabolites as Anticancer Agents
Diwan S. Rawat and Ram Singh
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Cytoskeletal Alterations That Confer Resistance to Anti-Tubulin Chemotherapeutics
Arun Kanakkanthara, Paul H. Teesdale-Spittle and John H. Miller
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Editorial: Survival Signaling through Focal Adhesion Kinase in Tumors
Vita Golubovskaya
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The Effects of β-Glucans on Dendritic Cells and Implications for Cancer Therapy
Sabrin Husein Albeituni and Jun Yan
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Editorial:Cytochrome P450 for cancer prevention and therapy
Tai C. Chen
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NFkB Down-regulation and PARP Cleavage by Novel 3-?-Butyryloxy-?-boswellic Acid Results in Cancer Cell Specific Apoptosis and in vivo Tumor Regression
Yasrib Qurishi, Abid Hamid, Parduman R. Sharma, Zahoor A. Wani, Dilip M. Mondhe, Shashank K. Singh, Mohmmad A. Zargar, Samar S. Andotra, Bhahwal A. Shah, Subhash C. Taneja and Ajit K. Saxena
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β-Glucans and their Applications in Cancer Therapy: Focus on Human Studies
Eiman Aleem
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Antitumoral activity of indole-3-carbinol cyclic tri- and tetrameric derivatives mixture in human breast cancer cells: in vitro and in vivo studies.
Giorgio Brandi, Alessandra Fraternale, Simone Lucarini, Mirko Paiardini, Mauro De Santi, Barbara Cervasi, Maria Filomena Paoletti, Luca Galluzzi, Andrea Duranti and Mauro Magnani
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Integrated Therapeutic Approaches in the Treatment of Human Cancer
Francesco Caponigro
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Cytotoxicity and cell death mechanisms induced by a Novel Bisnaphthalimidopropyl Derivative against the NCI-H460
Raquel T. Lima, Gemma A. Barron, Joanna A. Grabowska, Giovanna Bermano, Simranjeet Kaur, Nilanjan Roy, M. Helena Vasconcelos and Paul Kong Thoo Lin
View Abstract
Inhibition of PI3K/Akt/mTOR Signaling by Natural Products
Shile Huang
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Vitamin D supplementation and cancer: review of randomized controlled trials
Matteo Lazzeroni, Davide Serrano, Stefan Pilz and Sara Gandini
View Abstract
Vitamin D and cancer mortality: systematic review of prospective epidemiological studies
Stefan Pilz, Katharina Kienreich, Andreas Tomaschitz, Eberhard Ritz, Elisabeth Lerchbaum, Barbara Obermayer-Pietsch, Veronika Matzi, Joerg Lindenmann, Winfried März, Sara Gandini and Jacqueline M. Dekker
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Update on evidence that support a role of solar ultraviolet-B irradiance in reducing cancer risk
William B. Grant
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The anti-cancer actions of vitamin D
Kun-Chun Chiang and Tai C. Chen
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Sunlight Vitamin D and Skin Cancer
Rebecca S. Mason and Jörg Reichrath
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Vitamin D, Sunlight and Cancer Connection
Michael F. Holick
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Shedding Light on Serum Vitamin D Concentrations and the Risk of Rarer Cancers
Kathy J. Helzlsouer and Lisa Gallicchio
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