ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)


Volume 14, 10 Issues, 2014


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Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

Aims & ScopeAbstracted/Indexed in

Ranking and Category:
  • 22nd of 58 in Chemistry, Medicinal
  • 85th of 202 in Oncology

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Editor-in-Chief:
Michelle Prudhomme
Universite Blaise Pascal - C.N.R.S
Aubiere Cedex
France


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Current: 2.939
5 - Year: 3.37

Upcoming Articles (E-Pub Abstracts ahead of Print)

Berberine Interfered with Breast Cancer Cells Metabolism, Balancing Energy Homeostasis
Wen Tan, L i Ning, Rui Tan, Zhangfeng Zhong, Zhanwei Suo, Xian Yang, Yitao Wang and H u Xiaodong
View Abstract
A Novel Multiple Tyrosine-kinase Targeted Agent to Explore the Future Perspectives of Anti-Angiogenic Therapy for the Treatment of Multiple Solid Tumors: Cabozantinib
Subhajit Roy, Bawneet K. Narang, Shiva K. Rastogi and Ravindra K. Rawal
View Abstract
Anticancer and Antibacterial Activity of Hyperforin and Its Derivatives
Brigida Immacolata Pia Schiavone, Luisella Verotta, Antonio Rosato, Muraglia Marilena, Simon Gibbons, Ezio Bombardelli, Carlo Franchini and Filomena Corbo
View Abstract
Bleomycin induces sensitivity to TRAIL/Apo-2L-Mediated Apoptosis in Human Seminomatous Testicular Cancer Cells is Correlated with Upregulation of Death Receptors
Mujgan Timur, Aysegul Cort, Evrim Ozdemir, Sureyya Bilmen Sarikcioglu, Salih Sanlioglu, Ahter Dilsad Sanlioglu and Tomris Ozben
View Abstract
Organometallic Compounds in Cancer Therapy: Past Lessons and Future Directions
Pedro Martins, Mara Marques, Lídia Coito, Armando J.L. Pombeiro, Pedro Viana Baptista and Alexandra R Fernandes
View Abstract
The Interactions of Anticancer Agents with Teacatechins: Current Evidence from Preclinical Studies
Weihu Shang, Weidong Lu and Mei Han
View Abstract
Bergamot Juice Extract Inhibits Proliferation by Inducing Apoptosis in Human Colon Cancer Cells
Giuseppa Visalli, Nadia Ferlazzo, Santa Cirmi, Pietro Campiglia, Sebastiano Gangemi, Angela Di Pietro, Gioacchino Calapai and Michele Navarra
View Abstract
New Potent and Selective Inhibitor of Pim-1/3 Protein Kinases Sensitizes Human Colon Carcinoma Cells to Doxorubicin
Pascale Moreau, Lyubov G. Dezhenkova, Fabrice Anizon, Lionel Nauton, Vincent Thery, Shuguang Liang, Dmitry N. Kaluzhny and Alexander A. Shtil
View Abstract
Evaluation of Tricine and EDDA as Co-ligands for 99mTc-Labeled HYNIC-MSH Analogues for Melanoma Imaging
María Fernanda Garcíaa, Xiuli Zhang, Fabio Gallazzi, Marcelo Fernandeza, María Morenoe, Juan Pablo Gambini, Williams Porcal, Pablo Cabral and Thomas P. Quinn
View Abstract
New Perspective on the Dual Functions of Indirubins in Cancer Therapy and Neuroprotection
Ying Wang, Pui Man Hoi, Judy Yuet-Wa Chan and Simon Ming-Yuen Lee
View Abstract
Design, Synthesis and Biological Evaluation of Quinoxalin-2(1H)-One Derivatives as EGFR Tyrosine Kinase Inhibitors
Xuemei Qin, Xiao Han, Liming Hu, Zhipeng Li, Zhufeng Geng, Zhanyang Wang, Chengchu Zeng and Xiangqian Xiao
View Abstract
p42.3: An Abductor of Cell Cycle
Wen-Jia Cao, Lin-Lin Mao, Jun-Nian Zheng and Dong-Sheng Pei
View Abstract
Molecular Markers of Angiogenesis and Metastasis in Lines of Oral Carcinoma after Treatment with Melatonin
Naiane do Nascimento Goncaves, Rodrigo Ventura Rodrigues, Bruna Victorasso Jardim Perassi, Marina Gobbe Moschetta, Juliana Ramos Lopes, Jucimara Colombo and Debora Aparecida Pires de Campos Zuccari
View Abstract
Potential Anticancer Agents. II. Synthesis of Isoxazole Moiety Containing Quinazoline Derivatives and Preliminarily in vitro Anticancer Activity
Jianping Yong, Canzhong Lu and Xiaoyuan Wu
View Abstract
Antioxidant Activity and Chemical Components as Potential Anticancer Agents in the Olive Leaf (Olea europaea L. cv Leccino.) Decoction
Simona De Marino, Carmen Festa, Franco Zollo, Antonella Nini, Lina Antenucci, Gennaro Raimo and Maria Iorizzi
View Abstract
Synthesis and In Vitro Antiproliferative Activity of Thiazole-Based Nitrogen Mustards. The Hydrogen Bonding Interaction Between Model Systems and Nucleobases
Krzysztof Z. Łączkowski, Konrad Misiura, Marta Świtalska, Joanna Wietrzyk, Angelika Baranowska-Łączkowska, Berta Fernández, Agata Paneth and Tomasz Plech
View Abstract
Ellagic Acid Inhibits VEGF/VEGFR2, PI3K/Akt and MAPK Signaling Cascades in the Hamster Cheek Pouch Carcinogenesis Model
J Kowshika, Hemant Girib, Tanagala Kranthi Kiran Kishorea, Rushendhiran Kesavanb, Raju Naik Vankudavathc, Geereddy Bhanuprakash Reddyd, Madhulika Dixitb and Siddavaram Naginia
View Abstract
A Review on Antiproliferative and Apoptotic Activities of Natural Honey
Saravana Kumar Jaganathan, B Arunpandian, Muthu Vignesh Vellayappan, A Kumar Manjesh, Aruna Priyadarshini, Agnes John, Eko Supriyanto, Saiful Izwan Abd Razak and Mohsen Marvi
View Abstract
In Search of Natural Remediation for Cervical Cancer
Madhumita Roy, Apurba Mukherjee, Ruma Sarkar, Sutapa Mukherjee and Jaydip Biswas
View Abstract
A small-molecule inhibitor, 5'-O-tritylthymidine, targets FAK and Mdm-2 interaction, and blocks breast and colon tumorigenesis in vivo.
V M Golubovskaya, N L Palma, M Zheng, B Ho, A Magis, D Ostrov and WG Cance
View Abstract
Mitoxantrone Targets The ATP-Binding Site Of FAK, Binds The FAK Kinase Domain And Decreases FAK, Pyk-2, C-Src, And IGF-1R, In Vitro Kinase Activities
Vita Golubovskaya, Baotran Ho, Min Zheng, Andrew Magis, David Ostrov and William Cance
View Abstract
Quinones derived from plant secondary metabolites as anti-cancer agents
Jin-Jian Lu, Jiao-Lin Bao, Guo-Sheng Wu, Wen-Shan Xu, Ming-Qing Huang, Xiu-Ping Chen and Yi-Tao Wang
View Abstract
Syntetic Oligosacharides – Clinical Application in Cancer Therapy
Vaclav Vetvicka
View Abstract
Marine Natural Products and Related Compounds as Anticancer Agents: an Overview of their Clinical Status
Karina Petit and Jean-François Biard
View Abstract
Recent advance in the studies of Beta-glucans for cancer therapy

View Abstract
Antiangiogenic Triterpenes Isolated from Chinese Herbal Medicine Actinidia Chinensis Planch
Wen-Jun Zhu, De-Hong Yu, Mei Zhao, Meng-Gan Lin, Qin Lu, Qi-Wei Wang, Ying-Yun Guan, Gui-Xiu Li, Xin Luan, Yi-Fang Yang, Xue-Mei Qin, Chao Fang, Guo-Hong Yang and Hong-Zhuan Chen
View Abstract
New Insight into P-Glycoprotein as a Drug Target
Albert Breier, Lenka Gibalova, Mario Seres, Miroslav Barancik and Zdenka Sulova
View Abstract
Epigenetic Mechanisms Underlying Diet-Sourced Compounds in the Prevention and Treatment of Gastrointestinal Cancer
Rebecca W. Knackstedt, Vondina R. Moseley and Michael J. Wargovich
View Abstract
Selected Approaches for Rational Drug Design and High Throughput Screening to Identify Anti-Cancer Molecules
Michael Hedvat, Luni Emdad, Swadesh K. Das, Keetae Kim, Santanu Dasgupta, Shibu Thomas, Bin Hu, Shan Zhu, Rupesh Dash, Bridget A. Quinn, Regina A. Oyesanya, Timothy P. Kegelman, Upneet K. Sokhi, Siddik Sarkar and Eda Erdogan
View Abstract
Redox-inactive Analogue of Tocotrienol as a Potential Anti-cancer Agent
Tomohiro Yano, Ayami Sato, Miki Sekine, Nantiga Virgona and Masako Ota
View Abstract
Metformin: A Rising Star to Fight The Epithelial Mesenchymal Transition in Oncology
Guislaine Barriere, Michel Tartary and Michel Rigaud
View Abstract
The Effect of Quercetin On Doxorubicin Cytotoxicity in Human Breast Cancer Cells
Shi zheng Li, Kun Li, Jun-hua Zhang and Zhe Dong
View Abstract
Platinum Compounds: A Hope for Future Cancer Chemotherapy
Imran Ali, Waseem A. Wani, Kishwar Saleem and Ashanul Haque
View Abstract
Antineoplastic Activity of Monocrotaline against Hepatocellular Carcinoma
Sandeep Solmon Kusuma, Karunakar Tanneeru, Swroopa Didla, Bellary Nagaraju Devendra and Patnala Kiranmayi
View Abstract
Plant Coumestans: Recent Advances and Future Perspectives in Cancer Therapy
Tereza Nehybova, Jan Smarda and Petr Benes
View Abstract
White Poplar (Populus alba L.) Cell Suspension Cultures as a Model System to Study Apoptosis Induced by Alfalfa Saponins
Alma Balestrazzi, Daniela Carbonera, Pinarosa Avato and Aldo Tava
View Abstract
Improving the Efficacy of Plant Polyphenols
Lucia Biasutto, Andrea Mattarei, Nicola Sassi, Michele Azzolini, Matteo Romio, Cristina Paradisi and Mario Zoratti
View Abstract
Intracellular Distribution and Biological Effects of Phytochemicals in a Sex Steroid-Sensitive Model of Human Prostate Adenocarcinoma
Antonella Smeriglio, Domenico Trombetta, Daniele Marcoccia, Laura Narciso, Alberto Mantovani and Stefano Lorenzetti
View Abstract
Mesenchymal Stromal Cells Uptake And Release Paclitaxel Without Reducing Its Anticancer Activity
Massimo Mariotti, Renato Colognato, Marco Rimoldi, Manuela Rizzetto, Francesca Sisto, Valentina Cocce, Arianna Bonomi, Eugenio Parati, Giulio Alessandri, Renzo Bagnati and Augusto Pessina
View Abstract
Caspases and ROS - Dependent Mechanism of Action Mediated by Combination of WP 631 and Epothilone B
Aneta Rogalska, Barbara Bukowska and Agnieszka Marczak
View Abstract
Deoxypodophyllotoxin Isolated from Juniperus Communis Induces Apoptosis in Breast Cancer Cells
Sami Benzina, Jason Harquail, Stéphanie Jean, Annie-Pier Beauregard, Caitlyn D. Colquhoun, Madison Carroll, Allyson Bos, Christopher A. Gray and Gilles A Robichaud
View Abstract
Anti-Proliferative Activities of Terpenoids Isolated from Alisma Orientalis and their Structure-Activity Relationships
Wen Xu, Ting Li, Jian-Fang Qiu, Shui-Sheng Wu, Ming-Qing Huang, Gen-Li Lin, Qing-Wen Zhang, Xiu-Ping Chen and Jin-Jian Lu
View Abstract
Recent Developments on Thiourea Based Anticancer Chemotherapeutics
Vikas Kumar and Swapandeep Singh Chimni
View Abstract
Drug Target Strategies in Breast Cancer Treatment: Recent Developments
Vikas Jaitak
View Abstract
The Effects of β-glucans on Cancer Metastasis
Taek J. Yoon, Sushruta Koppula and Kwang H. Lee
View Abstract
Vitamin D and Breast Cancer Incidence and Outcome
Jianghua Liu, Deliang Cao and Rowan T. Chlebowski
View Abstract
Vitamin D, Sunlight, and the Epidemiology of Prostate Cancer
Gary G. Schwartz
View Abstract
Supplementation, Optimal Status, and Analytical Determination of Vitamin D: Where are we standing in 2012?
Jean-Claude Souberbielle and Etienne Cavalier
View Abstract
Role of Calcium, Vitamin D, and the Extrarenal Vitamin D Hydroxylases during Carcinogenesis
Julia Höbaus, Ursula Thiem, Doris M. Hummel and Enikö Kallay
View Abstract
Epidemiology of Vitamin D And Colorectal Cancer
Jianghua Liu, Deliang Cao and Edward Giovannucci
View Abstract
Recombinant Snake Venom Cystatin Inhibits Tumor Angiogenesis in vitro and in vivo Associated with Downregulation
Qun Xie, Nanhong Tang, Rong Wan, Yuanlin Qi, Xu Lin and Jianyin Lin
View Abstract
SJSZ glycoprotein (38 kDa) inhibits cell cycle and oxidative stress in N- Methyl-N`-nitro-N-nitrosoguanidine-induced ICR mice
Jin Lee and Kye-Taek Lim
View Abstract
N6-Isopentenyladenosine and its Analogue N6-Benzyladenosine Induce Cell Cycle Arrest and Apoptosis in Bladder
Sara Castiglioni, Silvana Casati, Roberta Ottria, Pierangela Ciuffreda and Jeanette A. M. Maier
View Abstract
The Role of Autophagic Cell Death and Apoptosis in Irinotecan-Treated P53 Null Colon Cancer Cells
Stanislav John, Jan Mls, Miroslav C(ervinka and Emil Rudolf
View Abstract
Type II kinase inhibitors: an opportunity in cancer for rational design
Javier Blanc, Raphaël Geney and Christel Menet
View Abstract
Biology and Medicinal Chemistry Approaches towards Various Apoptosis Inducers
Vivek K. Vyas, Chetan Chintha and Mitul R. Pandya
View Abstract
Synthesis and Antimicrobial Activity of Nitroalkenyl Arenes
Gina Nicoletti
View Abstract
Heterocyclic Chalcone Analogues as Potential Anticancer Agents
Vikas Sharma, Vipin Kumar and Pradeep Kumar
View Abstract
Azidothymidine is Effective against Human Multiple Myeloma: A New Use for an Old Drug?
Juliana Pereira, Debora Levy, Jorge LM Ruiz, Graciela A Brocardo, Kleber A Ferreira, Renata O Costa, Rodrigo G Queiroz, Durvanei A Maria, Abrahão E Hallack Neto, Dalton A F Chamone and Sérgio P Bydlowski
View Abstract
Oxaliplatin-Induced Hyperexcitation of Rat Sciatic Nerve Fibers: An Intra-Axonal Study
Alexia Kagiava, Efstratios K. Kosmidis and George Theophilidis
View Abstract
Histone Deacetylase Inhibitors as Potential Therapeutic Agents For The Treatment Of Malignant Mesothelioma
Patroklos Katafygiotis, Constantinos Giaginis, Efstratios Patsouris and Stamatios Theocharis
View Abstract
Carbon Nanotubes in The Diagnosis and Treatment of Malignant Melanoma
Naghmeh Naderi, Seyed Yazdan Madani, Afshin Mosahebi and Alexander M. Seifalian
View Abstract
Targeting Heme for the Identification of Cytotoxic Agents
Shiming Zhang, Hui Chen, Jessica Webster and Glenn S. Gerhard
View Abstract
Endocrine Therapy Resistance: Current Status, Possible Mechanisms and Overcoming Strategies
Jinjia Chang and Weimin Fan
View Abstract
The Therapeutical Potential of A Novel Pterocarpanquinone LQB-118 to Target Inhibitor Of Apoptosis Proteins In Acute Myeloid Leukemia Cells
Flaviana Ruade de Souza Reis, Fernanda Costas Casal de Faria, Carolina Pereira Castro, , Paloma Silva de Souza, Flavia da Cunha Vasconcelos,, Reinaldo Dal Bello, Alcides Jose da Silva, Paulo Roberto Ribeiro Costa and Raquel Ciuvalschi Maia
View Abstract
NADPH Oxidases NOXs and DUOXs As Putative Targets for Cancer Therapy
Urbain Weyemi, Christophe E. Redon, Palak R. Parekh, Corinne Dupuy and William M. Bonner
View Abstract
Plant-Derived Secondary Metabolites as Anticancer Agents
Diwan S. Rawat and Ram Singh
View Abstract
A Natural Anticancer Agent Thaspine Targets Human Topoisomerase IB
Silvia Castelli, Prafulla Katkar, Oscar Vassallo, Mattia Falconi, Stig Linder and Alessandro Desideri
View Abstract
Cytoskeletal Alterations That Confer Resistance to Anti-Tubulin Chemotherapeutics
Arun Kanakkanthara, Paul H. Teesdale-Spittle and John H. Miller
View Abstract
Human Skin-Derived Fibroblasts Acquire In Vitro Anti-Tumor Potential After Priming with Paclitaxel
Augusto Pessina, Valentina Cocce, Arianna Bonomi, Loredana Cavicchini, Francesca Sisto, Maura Ferrari, Emilio Ciusani, Stefania Navone, Giovanni Marfia, Eugenio Parati and Giulio Alessandri
View Abstract
Editorial: Survival Signaling through Focal Adhesion Kinase in Tumors
Vita Golubovskaya
View Abstract
Fak and Has Inhibition Synergistically Decrease Colon Cancer Cell Viability And Affect Expression Of Critical Genes
Melissa Heffler, Vita Golubovskaya, Jeffrey Conroy, Song Liu, Dan Wang, William Cance and Kelli Bullard Dunn
View Abstract
The Effects of β-Glucans on Dendritic Cells and Implications for Cancer Therapy
Sabrin Husein Albeituni and Jun Yan
View Abstract
Editorial:Cytochrome P450 for cancer prevention and therapy
Tai C. Chen
View Abstract
NFkB Down-regulation and PARP Cleavage by Novel 3-?-Butyryloxy-?-boswellic Acid Results in Cancer Cell Specific Apoptosis and in vivo Tumor Regression
Yasrib Qurishi, Abid Hamid, Parduman R. Sharma, Zahoor A. Wani, Dilip M. Mondhe, Shashank K. Singh, Mohmmad A. Zargar, Samar S. Andotra, Bhahwal A. Shah, Subhash C. Taneja and Ajit K. Saxena
View Abstract
β-Glucans and their Applications in Cancer Therapy: Focus on Human Studies
Eiman Aleem
View Abstract
The Application of Fungal Beta-glucans for the Treatment of Colon Cancer
Jiezhong Chen, Xu D. Zhang and Zhengyi Jiang
View Abstract
The use of lentinan for treating gastric cancer
Kenji Ina and Takafumi Ando
View Abstract
Antitumoral activity of indole-3-carbinol cyclic tri- and tetrameric derivatives mixture in human breast cancer cells: in vitro and in vivo studies.
Giorgio Brandi, Alessandra Fraternale, Simone Lucarini, Mirko Paiardini, Mauro De Santi, Barbara Cervasi, Maria Filomena Paoletti, Luca Galluzzi, Andrea Duranti and Mauro Magnani
View Abstract
Unified Multi-target Approach for the Rational In silico Design of Anti-bladder Cancer Agents
Alejandro Speck-Planche, Valeria V. Kleandrova, Feng Luan and M. Natalia D. S. Cordeiro
View Abstract
Integrated Therapeutic Approaches in the Treatment of Human Cancer
Francesco Caponigro
View Abstract
Cytotoxicity and cell death mechanisms induced by a Novel Bisnaphthalimidopropyl Derivative against the NCI-H460
Raquel T. Lima, Gemma A. Barron, Joanna A. Grabowska, Giovanna Bermano, Simranjeet Kaur, Nilanjan Roy, M. Helena Vasconcelos and Paul Kong Thoo Lin
View Abstract
Inhibition of PI3K/Akt/mTOR Signaling by Natural Products
Shile Huang
View Abstract
Multifunctionalized Microbubbles for Cancer Diagnosis and Therapy
Hao Li, Jianhao Wang, Gang Huang, Ping Wang, Rongqin Zheng, Chao Zhang and Qing Jiang
View Abstract
Vitamin D supplementation and cancer: review of randomized controlled trials
Matteo Lazzeroni, Davide Serrano, Stefan Pilz and Sara Gandini
View Abstract
Vitamin D and cancer mortality: systematic review of prospective epidemiological studies
Stefan Pilz, Katharina Kienreich, Andreas Tomaschitz, Eberhard Ritz, Elisabeth Lerchbaum, Barbara Obermayer-Pietsch, Veronika Matzi, Joerg Lindenmann, Winfried März, Sara Gandini and Jacqueline M. Dekker
View Abstract
Update on evidence that support a role of solar ultraviolet-B irradiance in reducing cancer risk
William B. Grant
View Abstract
The anti-cancer actions of vitamin D
Kun-Chun Chiang and Tai C. Chen
View Abstract
Computational and functional analysis of the androgen receptor antagonist atraric acid and its derivatives
Maria Papaioannou, Annu A. Soderholm, Wei Hong, Yifan Dai, Julia Roediger, Daniela Roell, Marie Thiele, Tommi H. Nyronen and Aria Baniahmad
View Abstract
Sunlight Vitamin D and Skin Cancer
Rebecca S. Mason and Jörg Reichrath
View Abstract
Vitamin D, Sunlight and Cancer Connection
Michael F. Holick
View Abstract
Shedding Light on Serum Vitamin D Concentrations and the Risk of Rarer Cancers
Kathy J. Helzlsouer and Lisa Gallicchio
View Abstract
Antiproliferative Activities on Renal, Prostate and Melanoma Cancer Cell Lines of Sarcopoterium Spinosum Aerial Parts and its Major Constituent Tormentic Acid
Monica R. Loizzo, Marco Bonesi, Nicodemo G. Passalacqua, Antoine Saab, Francesco Menichini and Rosa Tundis
View Abstract
Synthesis and Biological Evaluation of Novel Antifolate Analogs as Potential Anticancer Treatment
Dan F. Stoicescu and Maria Rotaru
View Abstract
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