Home Page ::: Letters in Drug Design & Discovery

ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)


Volume 11, 10 Issues, 2014


Download PDF Flyer




Letters in Drug Design & Discovery

Aims & ScopeAbstracted/Indexed in


Submit Abstracts Online Submit Manuscripts Online

Editor-in-Chief:

Atta-ur-Rahman

, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK
Email: lddd@benthamscience.org

View Full Editorial Board

Subscribe Purchase Articles Order Reprints

Current: 0.961
5 - Year: 0.917
Announcements



Endorsement(s)

"Letters in Drug Design & Discovery should be available in every library in the pharmaceutical industry and in universities."

R. F. Borne, Associate Director
Laboratory for Applied Drug Design and Synthesis, The University of Mississippi, USA

Forthcoming Special Issue(s)

Theoretical Studies for Drug Design derived from natural products: Isolation, Characterization and Biological activity of metabolites in degenerative diseases


Guest Editor(s): Francisco J. Prado-Prado
Tentative Publication Date: November, 2015
Submit Abstract via Email Download Description
Authors' Comments
Thank you very much for asking me to give a feedback about the “Letters in Drug Design & Discovery”. I always feel very comfortable whenever I submit any article to publish in this journal.
The review process is fast and sound. I always receive prompt replies from Ms. Aiman Islam and Ambreen Irshad. Both are very sincere and helpful. So far, four of my articles have been published in this journal and hopefully this number will be increased in the coming years. Moreover, I encouraged many of my colleagues to submit their paper in this journal.
Finally, “Letters in Drug Design & Discovery” is a very good journal and I hope to have better relationship in future.

Dr. Imtaiyaz Hassan Hassan
Has contributed:

Letters in Drug Design & Discovery

,

Volume 12

-

Number 3



Quantitative Structure – Activity Relationship Study on Saponins as Cytotoxicity Enhancers

; Pp: 166 - 171

Reneta Gevrenova, Alexander Weng, Laurence Voutguenne-Nazabadioko, Mayank Thakur and Irini Doytchinova


DOI: 10.2174/1570180811666140915221432


Abstract Purchase Reprints Eprints Rights & Permissions

  
  



The Disulfide Analogues of Isophosphoramide Mustard for Anticancer Therapy

; Pp: 172 - 179

Joanna Cytarska, Krzysztof Skowerski, Szymon Jaworski, Konrad Misiura, Beata Filip-Psurska and Joanna Wietrzyk


DOI: 10.2174/1570180811666141010001007


Abstract Purchase Reprints Eprints Rights & Permissions

  
  



6,7-Dimethoxyquinazolines as Potential Cytotoxic Agents: Synthesis and in vitro Activity

; Pp: 190 - 205

Mange Ram Yadav, Bishram Singh Chauhan, Prashant Naik, Hardik Gandhi and Rajani Giridhar


DOI: 10.2174/1570180811666141010000716


Abstract Purchase Reprints Eprints Rights & Permissions

  
  



Hybrid Pharmacophore Design and Synthesis of Naphthalimide-Benzimidazole Conjugates asPotential Anticancer Agents


Ahmed Kamal, Pogula Praveen Kumar, Mohammed Naseer Ahmed Khan, Bobburi Naga Sheshadri and Olepu Srinivas


View Abstract Purchase Online

  
  


Design, Synthesis and Biological Evaluation of Novel Fluorinated Heterocyclic Hybrid Molecules based on Triazole & Quinoxaline Scaffolds Lead to Highly Potent Antimalarials and Antibacterials


Adimulam Chandra Shekhar, Boddupally Pedda Venkat Lingaiah, Pamulaparthy Shanthan Rao, Banda Narsaiah, Aparna Devi Allanki and Puran Singh Sijwali


View Abstract Purchase Online

  
  


Promising anticancer drug Candidates based on the 7-Methoxychromone Scaffold: Synthesis and Evaluation of Antiproliferative Activity


Hoang Le Tuan Anh, Nguyen Thi Cuc, Pham Hai Yen, Nguyen Xuan Nhiem, Bui Huu Tai, Do Thi Thao, Nguyen Hoai Nam, Chau Van Minh, Phan Van Kiem and Young Ho Kim


View Abstract Purchase Online

  
  


First Discovery of Tylophora Alkaloids as HIV Inhibitors


Ziwen Wang, Mingxiao Wang, Lei Wang, Xue Yao, Yue Li, Juan Tan, Wentao Qiao, Yunqi Geng, Yuxiu Liu and Qingmin Wang


View Abstract Purchase Online

  
  


Discovery of Novel HDAC Inhibitors by Structure-Based Optimization of Cinnamic Hydroxamic Scaffold


Chengqing Ning, Wenyuan Huang, Wen Wu, Cheng Lu, Yujun He, Lei Yao, Lifei Liu, Xiaohe Zhen, Xiaoyu Liu and Niefang Yu


View Abstract Purchase Online

  
  


Development of Structure Activity Correlation Model on Azetidin-2-ones as Tubulin Polymerization Inhibitors


Vijay K. Patel, Kavibhushan S. Chouhan, Avineesh Singh, Deepak K Jain, Ravichandran Veerasamy, Pradeep K. Singour, Rajesh S. Pawar and Harish Rajak


View Abstract Purchase Online

  
  


Synthesis and Biological Activity of Acylthiourea Derivatives Contain 1,2,3-Thiadiazole and 1,3,4-Thiadiazole


Ming-Yan Yang, Wen Zhao, Zhao-Hui Sun, Cheng-Xia Tan, Jian-Quan Weng and Xing-Hai Liu


View Abstract Purchase Online

  
  


6-Bromo-2, 3-Dioxoindolin Phenylacetamide Derivatives: Synthesis, Potent CDC25B, PTP1B inhibitors and Anticancer Activity


Shui-Lian Zhao, Zhou Peng, Xing-Hua Zhen, Yan Han, Hai-Ying Jiang, You-Le Qu and Li-Ping Guan


View Abstract

  
  


FeCl3/Ultrasound mediated Reaction of 2-Aminothiophenol with Aldehydes in Water: Synthesis of 2-Substituted Benzothiazoles of Pharmacological Interest


Ponasanapalli Tirumala Venkata Ankayya Srinivas, Sallagundla Bhavani, Dandela Rambabu, Mandava Venkata Basaveswara Rao, Ravikumar Kapavarapu and Manojit Pal


View Abstract

  
  


Novel Fatty Acid Analogues as Human Fatty Acid Synthase Thioesterase Domain Inhibitors: Synthesis and Their Cytotoxicity Screening


Selvaraj Jubie, Pawan Kumar Yadhav, Moola Joghee Nanjan Chandrasekar, Jeyapal Gomathi Priya, Chaitanya MVNL and Palanisamy Dhanabal


View Abstract

  
  


Biological Properties of Heterocyclic Pyridinylimines and Pyridinylhydrazones


Francislene J. Martins, Rebeca Mol Lima, Juliana Alves dos Santos, Patrícia de Almeida Machado, Elaine Soares Coimbra, Adilson David da Silva and Nadia Rezende Barbosa Raposo


View Abstract

  
  


Synthesis of Six Phenylalanine Derivatives and their Cell Toxicity Effect on Human Colon Cancer Cell Line HT-29


Qianyi Zhao, Ting Xu, Menghua Li, Ying Yang, Haopeng Hu, Shupei Wang, Wenjuan Yan, Ran Chen, Chunyan Zhang and Cunshuan Xu


View Abstract

  
  


De Novo Design of High Potent DPP-IV Inhibitors Based on the Scaffold of Cyanopyrrolidine


Yu-Lei Jiang, Hao-Liang Yuan, Wei-Wei Zhang, Hai-Chun Liu, Yan-Min Zhang, Xiao Xiong, Jin-Xing Xu, Shuai Lu, Tao Lu and Ya-Dong Chen


View Abstract

  
  


Synthesis and Preliminary Biological Evaluation of New Heterocyclic Carboxamide Models


Kamal Sweidan, Jorn Engelmann, Walid Abu Rayyan, Dima Sabbah, Musa Abu Zarga, Tariq Al-Qirim, Yusuf Al-Hiari, Ghassan Abu Sheikha and Ghassan Shattat


View Abstract

  
  


The Disulfide Analogues of Isophosphoramide Mustard for Anticancer Therapy

, 2015; 12(3): 172 - 179

Joanna Cytarska, Krzysztof Skowerski, Szymon Jaworski, Konrad Misiura, Beata Filip-Psurska and Joanna Wietrzyk


DOI: 10.2174/1570180811666141010001007
View Abstract Purchase Online Rights and Permissions

  
  


Modeling the Active Conformation of Human µ Opioid Receptor

, 2014; 11(9): 1053 - 1061

Agnieszka A. Kaczor, Damian Bartuzi and Dariusz Matosiuk


DOI: 10.2174/1570180811666140322001506
View Abstract Purchase Online Rights and Permissions

  
  


In Vitro and In Vivo Investigations into the Carbene Copper Bromide Anticancer Drug Candidate WBC4

, 2014; 11(7): 825 - 832

Wolfgang Walther, Iduna Fichtner, Frauke Hackenberg, Wojciech Streciwilk and Matthias Tacke


DOI: 10.2174/1570180811666140529004102
View Abstract Purchase Online Rights and Permissions

  
  


Analysis of Proteasome Inhibition Prediction Using Atom-Based Quadratic Indices Enhanced by Machine Learning Classification Techniques

, 2014; 11(6): 705 - 711

Gerardo M. Casanola-Martin, Huong Le-Thi-Thu, Yovani Marrero-Ponce, Juan A Castillo- Garit, Francisco Torrens, Facundo Perez-Gimenez and Concepcion Abad


DOI: 10.2174/1570180811666140122001144
View Abstract Purchase Online Rights and Permissions

  
  


Potent Neuroprotective Activity of Monoterpene Derived 4-[(3aR,7aS)- 1,3,3a,4,5,7a-Hexahydro-3,3,6-trimethylisobenzofuran-1-yl]-2-methoxyphenol in MPTP Mice Model

, 2014; 11(5): 611 - 617

Alla V. Pavlova, Irina V. Il'ina, Ekaterina A. Morozova, Dina V. Korchagina, Svetlana Yu. Kurbakova, Irina V. Sorokina, Tatyana G. Tolstikova, Konstantin P. Volcho and Nariman F. Salakhutdinov


DOI: 10.2174/1570180811666131210000316
View Abstract Purchase Online Rights and Permissions

  
  


Synthesis and Anti-Proliferative Activity of New Biphenyle-Benzylidenethiazolidine- 2,4-dione Bis-Adducts Containing Various Heterocyclic Cores

, 2014; 11(3): 256 - 264

Maxime Meyer, Sandra Kuntz, Isabelle Grillier-Vuissoz, Helene Martin, Lysiane Richert, Stephane Flament, Yves Chapleur and Michel Boisbrun


DOI: 10.2174/15701808113106660080
View Abstract Purchase Online Rights and Permissions

  
  


Advertisement

Related Journals




Related eBooks




Webmaster Contact: urooj@benthamscience.org Copyright © 2014 Bentham Science