Home Page ::: Drug Metabolism Letters

ISSN: 1874-0758 (Online)
ISSN: 1872-3128 (Print)

Volume 9, 2 Issues, 2015

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Drug Metabolism Letters

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Chandra Prakash

Department of Drug Metabolism and Pharmacokinetics
Biogen Idec
Cambridge, MA

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Pro-oxidant Drugs and Cancer Therapy

Guest Editor(s): William L. Stone
Tentative Publication Date: December, 2015
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Drug Metabolism Letters


Volume 8


Number 1

A Proposed Screening Paradigm for Discovery of Covalent Inhibitor Drugs

; Pp: 19 - 30

Mehran F. Moghaddam, Yang Tang, Zhihong O’Brien, Samantha J. Richardson, Maria Bacolod, Prasoon Chaturedi, Julius Apuy and Ashutosh Kulkarni

DOI: 10.2174/1872312808666140317151735
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In Vitro Evaluation of Reversible and Time-Dependent Inhibitory Effects of Kalanchoe Crenata on CYP2C19 and CYP3A4 Activity

Charles Awortwe, Vamshi K. Manda, Cristina Avonto, Shabana I. Khan, Ikhlas A. Khan, Larry A. Walker, Patrick J. Bouic and Bernd Rosenkranz

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A Modified Procedure for Estimating the Impact of the Uptake on the Overall Biliary Clearance in Sandwich Culture of Rat Hepatocytes

Katalin Jemnitz, Monika Szabo, Attila Batai-Konczos, Pal Szabo, Balazs Magda and Zsuzsa Veres

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Human HepaRG Cells can be Cultured in Hanging-Drop Plates for Cytochrome P450 Induction and Function Assays

Norie Murayama, Takashi Usui, Nicky Slawny, Christophe Chesné and Hiroshi Yamazaki

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Anaerobic Metabolism of the Agro-Pesticide Nitroxinil by Bovine Ruminal Fluid

Ignacio Irazoqui, Alfonso Rodríguez, Estefanía Birriel, Martín Gabay, María Laura Lavaggi, José Luis Repetto, Cecilia Cajarville, Mercedes González and Hugo Cerecetto

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Sulfation of Phenylephrine by the Human Cytosolic Sulfotranserases

Akihiro Yamamoto, Jiwan Kim, Ming-Yih Liu, Katsuhisa Kurogi, Yoichi Sakakibara, Masahito Suiko and Ming-Cheh Liu

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A Systematic Evaluation of Solubility Enhancing Excipients to Enable the Generation of Permeability Data for Poorly Soluble Compounds in Caco-2 Model

Devang Shah, Sundeep Paruchury, Muralikrishna Matta, Gajendra Chowan, Murali Subramanian, Ajay Saxena, Matthew G. Soars, John Herbst, Roy Haskell, Punit Marathe and Sandhya Mandlekar

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Direct and Rapid Transcript Analysis Assay for CYP mRNA Expression and Inducibility in Human Primary Hepatocytes

Laura Mattinen, Jenni Kublbeck, Oona Rechardt, Paavo Honkakoski and Jari Rautio

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