ISSN: 1874-0758 (Online)
ISSN: 1872-3128 (Print)


Volume 8, 2 Issues, 2014


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Drug Metabolism Letters

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Editor-in-Chief:
Chandra Prakash
Department of Drug Metabolism and Pharmacokinetics
Biogen Idec
Cambridge, MA
USA


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Drug Metabolism Letters, Volume 7 - Number 1

Inhibition of Hepatobiliary Transporters by A Novel Kinase Inhibitor Contributes to Hepatotoxicity in Beagle Dogs; Pp: 15 - 22
John Scott Daniels, Yurong Lai, Sarah South, Po-Chang Chiang, Daniel Walker, Bo Feng, Rouchelle Mireles, Laurence O. Whiteley, Jeremy W. Mckenzie, Jeffrey Stevens, Robert Mourey, David Anderson and John W. Davis II
DOI: 10.2174/18723128112066660018
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Effects of Obesity Induced by High-Fat Diet on the Pharmacokinetics of Atazanavir in Rats; Pp: 39 - 46
Shinji Kobuchi, Keizo Fukushima, Hiroaki Aoyama, Yukako Ito, Nobuyuki Sugioka and Kanji Takada
DOI: 10.2174/18723128112066660016
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Lepidium Sativum but not Nigella Sativa Affects Carbamazepine Disposition in an Animal Model; Pp: 47 - 51
Khalid M. Alkharfy, Fahad I. Al-Jenoobi, Mohd. Aftab Alam, Abdullah M. Al-Mohizea, Saleh A. Al-Suwayeh, Hesham M. Korashy, RaoM. A. Khan and Iqbal Muzaffar
DOI: 10.2174/18723128112069990015
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Capillary Zone Electrophoresis for Separation and Quantitative Determination of Mexiletine and its Main Phase I Metabolites; Pp: 52 - 57
Claudio Bruno, Maria Maddalena Cavalluzzi, Alessia Carocci, Alessia Catalano, Carlo Franchini and Giovanni Lentini
DOI: 10.2174/18723128112069990011
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Metabolite Characterization of Anti-Cancer Agent Gefitinib in Human Hepatocytes
Prashant Surve, Selvan Ravindran, Arghya Acharjee, Himanshu Rastogi, Sudipta Basu and Pradnya Honrao
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A Proposed Screening Paradigm for Discovery of Covalent Inhibitor Drugs
Mehran F. Moghaddam, Yang Tang, Zhihong O’Brien, Samantha J. Richardson, Maria Bacolod, Prasoon Chaturvedi, Julius Apuy and Ashutosh Kulkarni
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Preclinical Drug Metabolism and Pharmacokinetics, and Prediction of Human Pharmacokinetics and Efficacious Dose of the Investigational Aurora A Kinase Inhibitor Alisertib (MLN8237)
Johnny J. Yang, Yu Li, Arijit Chakravarty, Chuang Lu, Cindy Q. Xia, Susan Chen, Sandeep Pusalkar, Mengkun Zhang, Jeffrey Ecsedy, Mark G. Manfredi, Wu Jing-Tao, Wen Chyi Shyu and Suresh K. Balani
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A Review of Pharmacokinetic Parameters of Metabolites and Prodrugs
Michel Leandro de Campos, Elias Carvalho Padilha and Rosangela Goncalves Peccinini
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