Home Page ::: Current Drug Targets

ISSN: 1873-5592 (Online)
ISSN: 1389-4501 (Print)


Volume 15, 14 Issues, 2014


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Current Drug Targets

Aims & ScopeAbstracted/Indexed in

Ranking and Category:
  • 52nd of 254 in

    Pharmacology & Pharmacy


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Editor-in-Chief:

Francis J. Castellino


Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556
USA


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Current: 3.597
5 - Year: 3.558
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Endorsement(s)

"In view of the growing volume of literature, the role of high quality review journals has become increasingly important. Current Drug Targets is an important journal in the field of medicinal chemistry and drug design, which is strongly recommended to the scientific community."

Jean-Marie Lehn
Nobel Laureate

Forthcoming Special Issue(s)

EBMT Educational Meeting from the Severe Aplastic Anaemia and Infectious Diseases Working Parties


Guest Editor(s): Carlo Dufour Simone Cesaro, Antonio M. Risitano, Regis Peffault De Latour
Tentative Publication Date: April, 2015
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Published Special Issue(s)

By-Products As Scaffolds For Drug Delivery Systems: Design, Targeting Approaches, And Sustainability


Guest Editor(s): Luciano P Silva, Graziella A Joanitti
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Authors' Comments
I really appreciate working with Bentham Science Publishers. It was a pleasure to collaborate with Ms. Shabana Seemee and Ms. Samina Khan, as they expressed a high level of professionalism. Moreover, their advices and suggestions concerning revision of the manuscript were clear and allowed fruitful assistance.
Our submission is likely to be of interest to the pharmaceutical and biomedical industry.
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Thank you very much for cooperation.

Dr. Wojciech Miltyk
Has contributed: αIIbβ3-Integrin Ligands: Abciximab and Eptifibatide as Proapoptotic Factors in MCF-7 Human Breast Cancer Cells

Current Drug Targets

,

Volume 15

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Number 14



Epidermal Growth Factor Receptor Targeting in Non-Small Cell Lung Cancer: Revisiting Different Strategies Against the Same Target

; Pp: 1273 - 1283

Eduardo Castanon, Patricia Martin, Christian Rolfo, Juan P. Fusco, Lucia Ceniceros, Jairo Legaspi, Marta Santisteban and Ignacio Gil-Bazo


DOI: 10.2174/138945011514141216092935
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The Role of cMet in Non-Small Cell Lung Cancer Resistant to EGFRInhibitors: Did We Really Find the Target?

; Pp: 1284 - 1292

Francesco Passiglia, Nele Van Der Steen, Luis Raez, Patrick Pauwels, Ignacio Gil-Bazo, Edgardo Santos, Daniele Santini, Giovanni Tesoriere, Antonio Russo, Giuseppe Bronte, Karen Zwaenepoel, Federico Cappuzzo and Christian Rolfo


DOI: 10.2174/138945011514141216092739
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Targeting c-MET/HGF Signaling Pathway in Upper Gastrointestinal Cancers: Rationale and Progress

; Pp: 1302 - 1311

Sharareh Gholamin, Hamid Fiuji, Mina Maftouh, Reza Mirhafez, Fatemeh Homaei Shandiz and Amir Avan


DOI: 10.2174/1389450115666141107105456
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Modulation of Signaling Enhances the Efficacy of the Combination of Satraplatin and Erlotinib

; Pp: 1312 - 1321

Abolfazl Avan, Auke D. Adema, Eveline K. Hoebe, Charlotte M. Huijts, Amir Avan, Gareth J. Veal, Rob Ruijtenbeek, Katja Wosikowski and Godefridus J. Peters


DOI: 10.2174/1389450115666141107110321
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The EGFR Pathway Regulates BCRP Expression in NSCLC Cells: Role of Erlotinib

; Pp: 1322 - 1330

Letizia Porcelli, Elisa Giovannetti, Yehuda G. Assaraf, Gerrit Jansen, George L. Scheffer, Ietje Kathman, Amalia Azzariti, Angelo Paradiso and Godefridus J. Peters


DOI: 10.2174/1389450116666141205145620
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Inhibition of the VEGF/VEGFR Pathway Improves Survival in Advanced Kidney Cancer: A Systematic Review and Meta-Analysis


Roberto Iacovelli, Cora N. Sternberg, Camillo Porta, Elena Verzoni, Filippo de Braud, Bernard Escudier and Giuseppe Procopio


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Affinity-Based Methods in Drug-Target Discovery


Gabriela Rylova, Tomas Ozdian, Lakshman Varanasi, Miroslav Soural, Jan Hlavac, Dusan Holub, Petr Dzubak and Marian Hajduch


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PDE-5 Inhibitors: Clinical Points


Michael Doumas, Antonios Lazaridis, Niki Katsiki and Vasilios Athyros


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Management of Peyronie's Disease after Collagenase (Xiaflex®)


Amjad Alwaal, Ahmed Aly Hussein, Uwais B. Zaid and Tom F. Lue


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Targeting the Root Cause of Cystic Fibrosis


Laura Trescott, Joshua Holcomb, Nicholas Spellmon, Cathy Mcleod, Leala Aljehane, Fei Sun, Chunying Li and Zhe Yang


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Advanced Nanomedicines for the Treatment and Diagnosis of Myocardial Infarction and Heart Failure


Mónica P. A. Ferreira, Vimalkumar Balasubramanian, Jouni Hirvonen, Heikki Ruskoaho and Hélder A. Santos


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Anti-IgE Therapy with Omalizumab for Severe Asthma: Current Concepts and Potential Developments


Girolamo Pelaia, Alessandro Vatrella, Maria Teresa Busceti, Luca Gallelli, Rosa Terracciano and Rosario Maselli


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Intracellular Ca2+ Signals to Reconstruct a Broken Heart: Still a Theoretical Approach?


Francesco Moccia, Federico Alessandro Ruffinatti and Estella Zuccolo


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PDZ Structure and Implication in Selective Drug Design against Cystic Fibrosis


Joshua Holcomb, Nicholas Spellmon, Laura Trescott, Fei Sun, Chunying Li and Zhe Yang


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Targeting ENaC as a Molecular Suspect in Cystic Fibrosis


Nadine Bangel-Ruland, Katja Tomczak and Wolf-Michael Weber


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Next Generation Sequencing In Non-Small Cell Lung Cancer: New Avenues Toward The Personalized Medicine


Simona Coco, Anna Truini, Irene Vanni, Maria Giovanna Dal Bello, Angela Alama, Erika Rijavec, Carlo Genova, Giulia Barletta, Claudio Sini, Giovanni Burrafato, Federica Biello, Francesco Boccardo and Francesco Grossi


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Micrornas As Tools And Effectors For Patient Treatment In Gastrointestinal Carcinogenesis


Edoardo D`Angelo, Caterina Vicentini, Marco Agostini, Andras Kiss, Raffaele Baffa, Aldo Scarpa and Matteo Fassan


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Image Guidance in Stem Cell Therapeutics: Unfolding the Blindfold


Amirali B. Bukhari, Shruti Dutta and Abhijit De


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Aqueous Extracts of Selected Potentilla Species Modulate Biological Activity of Human Normal Colon Cells


Roman Paduch, Adrian Wiater, Marcello Locatelli, Małgorzata Pleszczyńska and Michał Tomczyk


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Stem cell aging and age-related cardiovascular disease: Perspectives of treatment by ex-vivo stem cell rejuvenation


Madonna Rosalinda, Engel B. Felix, M Davidson Sean, Ferdinandy Péter, Görbe Anikó, P.G. Sluijter Joost and W Van Laake Linda


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Synergistic Activity of the c-Met and Tubulin Inhibitor Tivantinib (ARQ197) with Pemetrexed in Mesothelioma Cells

, 2014; 15(14): 1331 - 1340

Leticia G. Leon, Maria Gemelli, Rocco Sciarrillo, Amir Avan, Niccola Funel and Elisa Giovannetti


DOI: 10.2174/1389450116666141205160924
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Targeting SUMOylation Cascade for Diabetes Management

, 2014; 15(12): 1094 - 1106

Dornadula Sireesh, Elango Bhakkiyalakshmi, Kunka Mohanrama Ramkumar, Shanmugakani Rathinakumar, Panneer Selvam Anto Jennifer, Palanisamy Rajaguru and Ramasamy Paulmurugan


DOI: 10.2174/1389450115666140915124747
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