E-Pub Articles Ahead of Print ::: Medicinal Chemistry

ISSN: 1875-6638 (Online)
ISSN: 1573-4064 (Print)


Volume 13, 8 Issues, 2017


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Medicinal Chemistry

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Editor-in-Chief:
Dimitra Hadjipavlou-Litina
Aristotle University of Thessaloniki
Thessaloniki
Greece


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Articles Ahead of Print

iRNA-2methyl: Identify RNA 2′-O-methylation Sites by Incorporating Sequence-Coupled Effects into General PseKNC and Ensemble Classifier


Wang-Ren Qiu, Shi-Yu Jiang , Bi-Qian Sun, Xuan Xiao, Xiang Cheng and Kuo-Chen Chou.


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Biology-Oriented Synthesis (BIOS) of Piperine Derivatives and their Comparative Analgesic and Antiinflammatory Activities


Ammar Yasir, Saiqa Ishtiaq, Muhammad Jahangir, Muhammad Ajaib, Uzma Salar and Khalid Mohammed Khan.


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Synthesis and Antimalarial Activity of New Enantiopure Aminoalcoholpyrrolo[ 1,2-a]quinoxalines


Alexia Jonet, Jean Guillon, Catherine Mullié, Anita Cohen, Guillaume Bentzinger, Jérémy Schneider, Nicolas Taudon, Sebastien Hutter, Nadine Azas, Stephane Moreau, Solene Savrimoutou, Patrice Agnamey, Alexandra Dassonville-Klimpt and Pascal Sonnet.


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Cell Cycle Arrest and Apoptosis Induction Activity of Nitidine Chloride on Acute Myeloid Leukemia Cells


Peng Li, Shuxin Yan, Xin Dong, Zhao Li, Yu Qiu, Chunyan Ji, Jingru Zhang, Min Ji, Wei Li, Hongchun Wang, Zhi Liu, Xing Li Wang, Jingjing Ye and Daoxin Ma.


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Evaluation of 1,3-benzoxathiol-2-one Derivatives as Potential Antifungal Agents


Luciana Terra, Eliza de L. Chazin, Paola de S. Sanches, Max Saito, Marcus V.N. de Souza, Claudia R.B. Gomes, James L. Wardell, Solange M.S.V. Wardell, Plínio C. Sathler, Gabriela C.C. Silva, Viviane O. Lione, Marcos Kalil, Ana Joffily, Helena C. Castro and Thatyana RA Vasconcelos.


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Synthesis, Structural Characterization and Antinociceptive Activities of New Arylated Quinolines via Suzuki-Miyaura Cross Coupling Reaction


Malik Aman Ullah, Muhammad Adeel, Muhammad N. Tahir, Abdur Rauf, Muhammad Akram, Taibi Ben Hadda, Yahia N. Mabkhot, Naveed Muhammad, Fehmida Naseer and Mohammad S Mubarak.


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Rapid Access to Oxazine Fused Furocoumarins and in vivo and in silico Studies of Theirs Biological Activity


Alla V. Lipeeva, Dmitry S. Baev, Margarita P. Dolgikh, Tatijana G. Tolstikova and Elvira E Shults.


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Effect on Acetylcholinesterase and Anti-oxidant Activity of Synthetic Chalcones having a Good Predicted Pharmacokinetic Profile


Renata Parruca Sakata, Micheli Figueiro, Daniel Fabio Kawano and Wanda Pereira Almeida.


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Synthesis and Analgesic Activity of Amines Combining Diazaadamantane and Monoterpene Fragments


Konstantin Ponomarev, Ekaterina Morozova, Alla Pavlova, Evgeniy Suslov, Dina Korchagina, Andrej Nefedov, Tat`yana Tolstikova, Konstantin Volcho and Nariman Salakhutdinov.


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Quinolinic Carboxylic Acid Derivatives as Potential Multi-target Compounds for Neurodegeneration: Monoamine Oxidase and Cholinesterase Inhibition


Nehal Afreen Khan, Imtiaz Khan, Syed Mobasher Ali Abid, Sumera Zaib, Aliya Ibrar, Hina Andleeb, Shahid Hameed and Jamshed Iqbal.


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Isolation of Chlorogenic Acid from Soil Borne Fungi Screlotium rolfsii, their Reversal of Multidrug Resistance and anti-proliferative in Mouse Lymphoma Cells


Bashir Ahmad, Muhammad Rizwan, Abdur Rauf , Muslim Raza, Shumaila Bashir , Joseph Molnáre, Ákos Csonka, Diána Szabó, Mohammad S. Mubarak, Mah Noor and Bina S Siddiqui.


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The Role of QSAR and Virtual Screening Studies in Type 2 Diabetes Drug Discovery


Simone Q. Pantaleão, Drielli G.V. Fujii, Vinícius G. Maltarollo, Danielle da C. Silva, Gustavo H.G. Trossini, Karen C. Weber, Luis P.B. Scott and Kathia M Honorio.


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Synthesis and Biological Evaluation of Curcumin-Nitroxide-Based Molecular Hybrids as Antioxidant and Anti-Proliferative Agents


Balázs Bognár, Muthulakshmi Kuppusamy, Esha Madan, Tamás Kálai, Mária Balog, József Jekő, Periannan Kuppusamy and Kálmán Hideg.


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Better Predictive Value of Cancer Antigen125 (CA125) as Biomarker in Ovary and Breast Tumors and its Correlation with the Histopathological Type/Grade of the Disease


Aarifa Nazmeen, Smarajit Maiti, Kusumita Mandal, Samir K. Roy, Tamal Kanti Ghosh, Nirmalya K. Sinha and Kamalika Mandal.


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Synthesis of New Arylidene 2,5-Diketopiperazines and Evaluation of Their Anti-Acetylcholinesterase, Anti-xanthine Oxidase, Anti-diabetic and Cytotoxic Activities


Mohamed Amine Belkacem, Hichem Ben Jannet, Hicham Ferhout, Laila Mzali and Jalloul Bouajila.


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Identification of Novel 5,6-dimethoxyindan-1-one Derivatives as Antiviral Agents


Siddappa A. Patil, Vikrant Patil, Renukadevi Patil, Kenneth Beaman and Shivaputra A Patil.


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In vitro and in silico Studies of Mangiferin from Aphloia theiformis on Key Enzymes Linked to Diabetes Type 2 and Associated Complications


Marie C.N Picot, Gokhan Zengin, Adriano Mollica, Azzurra Stefanucci, Simone Carradori and Mohamad F Mahomoodally.


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Synthesis and Preliminary Cytotoxicity Studies of 1-[1-(4,5-Dihydrooxazol- 2-yl)-1H-indazol-3-yl]-3-phenylurea and 3-phenylthiourea Derivatives


Anita Kornicka, Franciszek Sączewski, Patrick J. Bednarski, Martyna Korcz, Piotr Szumlas, Ewa Romejko, Aneta Sakowicz, Łukasz Sitek and Monika Wojciechowska.


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Synthesis, Characterization and Cholinesterase Inhibition Studies of New Arylidene Aminothiazolylethanone Derivatives


Jamshed Iqbal, Ghulam Shabir, Fayaz A. Larik, Shafi Ullah Khan, Aamer Saeed, Muhammad S. Shah and Pervaiz A Channar.


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Additive Effect of MCP in Combination with Cefotaxime Against Staphylococcus aureus


Elias Dahdouh, Salah El-Khatib, Elias Baydoun and Roula M Abdel-Massih.


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A Simple Method to Predict Blood-Brain Barrier Permeability of Drug- Like Compounds Using Classification Trees


Juan A. Castillo-Garit, Gerardo M. Casañola-Martin, Huong Le-Thi-Thu, Hai Pham-The and Stephen J Barigye.


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A Concise Update on the Relevance of Secretory Phospholipase A2 Group IIA and Its Inhibitors to Cancer


Juan Chen, Long Ye, Yu Sun and Yoshikazhu Takada.


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Bioactive Constituents from an Endophytic Fungus, Penicillium polonicum NFW9, Associated with Taxus fauna


Nighat Fatima, Tawanun Sripisut, Ui Joung Youn, Safia Ahmed, Ihsan Ul-Haq, Ulyana Muñoz-Acuña, Charles J. Simmons, Muneer Ahmed Qazi, Muniba Jadoon, Ghee Teng Tan, Esperanza J. Carcache de Blanco and Leng Chee Chang.


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A New Anti-Aging Lysophosphatidic Acid from Arabidopsis thaliana


Yujuan Sun, Yanhui Wang, Guangfa Wang, Lan Xiang and Jianhua Qi.


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Synthesis of Adamantane Aminoethers with Antitubercular Potential


Angeliki-Sofia Foscolos, Ioannis Papanastasiou, Andrew Tsotinis, Nicolas Kolocouris, George B. Foscolos, Anthony Vocat and Stewart T Cole.


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Current medical treatment of early breast cancer


Franco Lumachi.





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