E-Pub Articles Ahead of Print ::: Medicinal Chemistry

ISSN: 1875-6638 (Online)
ISSN: 1573-4064 (Print)

Volume 10, 8 Issues, 2014

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Medicinal Chemistry

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Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Email: mc@benthamscience.org

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E-Pub Articles Ahead of Print

Synthesis of New Thiazolo[4,5-d]pyrimidines as Corticotropin Releasing Factor Modulators
Bhimanna Kuppast, Katerina Spyridaki, Christophina Lynch, Yueshan Hu, George Liapakis, Gareth E. Davies and Hesham Fahmy
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Inflammation Fueling Atrial Fibrillation Substrate: Seeking Ways to “Cool” the Heart
Georgios Giannopoulos, Michael W Cleman and Spyridon Deftereos
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Treating Dyslipidemias: Is Inflammation the Missing Link?
Nikolaos Papoutsidakis, Spyridon Deftereos, Georgios Giannopoulos, Vasiliki Panagopoulou, Antonis S. Manolis and Georgios Bouras
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Innate Immune Inflammatory Response in the Acutely Ischemic Myocardium
Spyridon Deftereos, Christos Angelidis, Georgios Bouras, Konstantinos Raisakis, Ulrich Gerckens, Michael W. Cleman and Georgios Giannopoulos
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Inflammation Markers in Essential Hypertension
Dimitrios Tsounis, Georgios Bouras, Georgios Giannopoulos, Charalampos Papadimitriou, Dimitrios Alexopoulos and Spyridon Deftereos
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Inflammation and Chronic Heart Failure: From Biomarkers to Novel Anti-inflammatory Therapeutic Strategies
Georgios Bouras, Georgios Giannopoulos, George Hatzis, Dimitrios Alexopoulos, George Leventopoulos and Spyridon Deftereos
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Quinoxaline Derivatives: Novel and Selective Butyrylcholinesterase Inhibitors
Aurang Zeb, Abdul Hameed, Latifullah Khan, Imran Khan, Kourosh Dalvandi, M. Iqbal Choudhary and Fatima Z. Basha
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Antiglycation Activity of Quinoline Derivatives- A New Therapeutic Class for the Management of Type 2 Diabetes
Bilquees Bano, Sanaullah Abbasi, Jalaluddin A. J. Khan, Shafqat Hussain, Saima Rasheed, Shahnaz Perveen, Khalid Mohammed Khan and M. Iqbal Choudhary
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Functionalization of Tetracycline and Evaluation of its Antibacterial Activity Including Against Resistant Bacteria
Priyanka Dogra and Ghanshyam S. Chauhan
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Synthesis and In Vitro Evaluation of Tropane Halogenated-derivatives against Malaria, Sleeping Sickness, Chagas Disease and Leishmaniasis
Sylvian Cretton, Trixie A. Bartholomeusz, Florence Mehl, Yves Allenbach, An Matheeussen, Paul Cos, Louis Maes and Philippe Christen
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Syntheses and N-methyl-D-aspartate Receptor Antagonist Pharmacology of Fluorinated Arylcycloheptylamines
Shengguo Sun, Jason Wallach and Adeboye Adejare
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Synthesis and First Evaluation of [18F]Fluorocyano- and [18F]Fluoronitroquinoxalinedione as Putative AMPA Receptor Antagonists
Sebastian Olma, Johannes Ermert, Wiebke Sihver and Heinz H. Coenen
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Virtual Screening for Cholesterol Absorption Inhibitors
Lidan Sun, Hai Qian and Wenlong Huang
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Synthesis of 2´-hydroxy-4´-Isoprenyloxychalcone Derivatives with Potential Antidepressant-Like Activity
Chao Xie, Yan Han, Zhao Shui-Lian, Pan Cheng-Yan, Guan Li-Ping and Sun Xian-Yu
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Synthesis and Biological Evaluation of Sulfonilamidothienopyrimidinone Derivatives as Novel Anti-inflammatory Agents
Mariarita Barone, Adriana C. E. Graziano, Cosimo G. Fortuna, Giuseppe Ronsisvalle and Venera Cardile
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Seeds of Peganum harmala L. Chemical Analysis, Antimalarial and Antioxidant Activities, and Cytotoxicity Against Human Breast Cancer Cells
Naziha Chabir, Hany Ibrahim, Mehrez Romdhane, Alexis Valentin, Béatrice Moukarzel, Mohamed Mars and Jalloul Bouajila
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Editorial: Targeting Inflammation in Cardiovascular Disease
Spyridon Deftereos and Georgios Bouras
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Electronic-Topological and Neural Network Approaches to the Structure- Antimycobacterial Activity Relationships Study On Hydrazones Derivatives
Fatma Kandemirli, Can Dogan Vurdu, Murat Alper Başaran, Hakan Sezgin Sayiner, Nathaly Shvets, Anatholy Dimoglo, Vasyl Kovalish and Turgay Polat
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Development of Thieno[3’,2’:5,6]thiopyrano[4,3-c]pyrazole-3-carboxamide Derivatives as the Estrogen Receptor Ligands: Synthesis, Characterization and Biological Activity
Xin Wang, Rui Sun, Yushu Huang, Yisi Yan, Miaomiao Gao, Wang Dan-Ni, Diwa Koirala, Li Da-Wei and Chun Hu
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Synthesis and Biological Activity of Anthrapyrazoles Derivatives as Potential Antitumor Agents
Jianhong Wang, Huijun Zhao, Zhaoyang Luo, Zhaoyi Wang, Yahong Zhang and Jin Zhao
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Preparation, in vitro Screening and Molecular Modelling of Monoquaternary Compounds Related to the Selective Acetylcholinesterase Inhibitor BW284c51
Ondrej Benek, Kamil Musilek, Anna Horova, Vlastimil Dohnal, Rafael Dolezal and Kamil Kuca
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Benzothiazole Derivatives: Novel Inhibitors of Methylglyoxal Mediated Glycation of Proteins In Vitro
Sanaullah Abbasi<sup>a</sup>, Salma Mirza<sup>b</sup>, Saima Rasheed<sup>b</sup>, Shafqat Hussain<sup>b</sup>, Jalaluddin A. J. Khan<sup>a</sup>, Khalid Mohammed Khan<sup>b</sup>, Shahnaz Perveen<sup>c</sup>, M. Iqbal Choudhary<sup>a and b</sup>
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Design, Synthesis and Pharmacological Evaluation of N3 Aryl/heteroaryl Substituted 2–((Benzyloxy and Phenylthio) Methyl) 6,7–Dimethoxyquinazolin–4(3H)–Ones as Potential Anticonvulsant Agents
Nirupam Das, Anupam G. Banerjee and Sushant K. Shrivastava
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Apolipoprotein E Gene Variants of Alzheimer’s Disease and Vascular Dementia Patients in a Community Population of Nanking
Chu Wen-Zheng, Li Gong, Xu Ying-Qiu, Cai Guo-Hua and Chou Kuo-Chen
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Novel Selenosemicarbazone Metal Complexes Exert Anti-Tumor Effect Via Alternative, Caspase-Independent Necroptotic Cell Death
Manja Zec, Tatjana Srdic-Rajic, Ana Krivokuca, Radmila Jankovic, Tamara Todorovic, Katarina Anđelkovic and Sinisa Radulovic
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Synthesis, Crystal structure, Anti-inflammatory and Anti-hyperglycemic Activities of Novel 3,4-Disubstituted 1,2,4-Triazol-5(4H)-one Derivatives
Muhammad Saleem, Yu Seon-Mi, Muhammad Rafiq, Kim Song-Ja, Seo Sung-Yum and Ki Hwan Lee
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Synthesis, Anticonvulsant and Antimicrobial Activities of Some New [1-(2-Naphthyl)-2-(pyrazol-1-yl)ethanone]oxime Ethers
Zeynep Özdemir, Arzu Karakurt, Ünsal Çaliş, Selami Günal, Şamil Işik, Z. Sibel Şahin and Sevim Dalkara
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Design, Synthesis and Biological Evaluation of Substituted Guanidine Indole Derivatives as Potential Inhibitors of HIV-1 Tat–TAR Interaction
Jun Wang, Yan Wang, Rujun Bai, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq and Xinyong Liu
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Synthesis and Anti-cancer Activities of Apigenin Derivatives
Xing Zheng, Liuying Yu, Jing Yang, Xu Yao, Wenna Yan, Shaowei Bo, Ya Liu, Yun Wei, Zhiyi Wu and Guan Wang
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Synthesis and Antimicrobial Evaluation of Novel bis-β-Lactam Grafted Macrocycles
Natarajan Arumugam, Abdulrahman I. Almansour, Raju Suresh Kumar, Raju Rajesh, Govindasami Periyasami and Raghavachary Raghunathan
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β-Glucuronidase Inhibitory Studies on Coumarin Derivatives
Khalid Mohammed Khan, Muhammad Imran Fakhri, Nimra Naveed Shaikh, Syed Muhammad Saad, Shafqat Hussain, Shahnaz Perveen and Muhammad Iqbal Choudhary
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Design and Synthesis of Quinazolinone Derivatives as Anti-inflammatory Agents: Pharmacophore Modeling and 3D QSAR Studies
P. Chaitanya, G. Deepak Reddy, G. Varun, L. M. Srikanth, V.V.S. Rajendra Prasad and A. Ravinder Nath
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Editorial: Targeting Inflammation in Cardiovascular Disease
Spyridon Deftereos and Georgios Bouras
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Mechanisms of Involvement of Eicosanoids and their Precursors in the Pathophysiology and Treatment of Schizophrenia
Luise Schmidt, Uta Ceglarek, Linda Kortz, Marcus Hoop, Kenneth Clifford Kirkby, Joachim Thiery and Hubertus Himmerich
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Impact of Clozapine, N-Desmethylclozapine and Chlorpromazine on Thromboxane Production in Vitro
Hubertus Himmerich, Luise Schmidt, Susen Becker, Linda Kortz, Jeremias Schönherr, Roland Mergl, Katrin Bauer, Ulrich Sack, Abigail J. Sheldrick, Joachim Thiery and Uta Ceglarek
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