E-Pub Articles Ahead of Print ::: Letters in Drug Design & Discovery

ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)


Volume 12, 10 Issues, 2015


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Letters in Drug Design & Discovery

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Editor-in-Chief:
Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK
Email: lddd@benthamscience.org

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E-Pub Articles Ahead of Print

Design, Synthesis and Evaluation of Novel 9-substituted Carbazole Derivatives as Potential Anticancer Agents
Nitin Kumar and Devender Pathak
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In Silico Molecular Interaction Studies of Chiral Heterocyclic Analogs of SAHA as Selective Histone Deacetylase 8 Inhibitors
Appavoo Umamaheswari, Navabshan Irfan and Ayarivan Puratchikody
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An Insight into Patents of Fluoroquinolone Derivatives
Prabodh Chander Sharma, Mona Piplani and Harish Rajak
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Psychoemotional Background of Temporomandibular Joint Dysfunction and Possible drug Therapy
Pihut Malgorzata, Gierowski Krzysztof, Ceranowicz Piotr and Ferendiuk Ewa
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Synthesis and Cytotoxicities of 2-[4-Hydroxy-(3, 5-Bis-Aminomethyl)-Benzylidene]-Indan-1-ones
Mehtap Tugrak, Halise Inci Gul and Hiroshi Sakagami
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A Review on Recent Robotic and Analytic Technologies in High Throughput Screening and Synthesis for Drug Discovery
Min Zhu
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QSAR Studies on the Bioactivity of Plasmodium Falciparum Glucose-6-Phosphate Dehydrogenase Inhibitors
Xiaoli Hou, Yue Kong, Maolin Wang and Aixia Yan
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HIF Inhibitors: New Hope for Cancer Therapy
Mayur Poddar, Tejraj M. Aminabhavi and Malleshappa N. Noolvi
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Oxime Carbamates as Potential Insecticidal Agents: Design, Synthesis and Biological Evaluation
Shaoyong Ke, Ziwen Yang, Liqiao Shi, Manli Liu, Ying Liang, Kaimei Wang, Aibing Jiang and Zhigang Zhang
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Application of Agents Against Interferon-Gamma-Dependent Chemokines in Immunotherapy
Poupak Fallahi, Silvia Martina Ferrari, Dilia Giuggioli, Clodoveo Ferri and Alessandro Antonelli
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Exploring Structure-Based Drug Design for the Development of Multi-Target Antihypertensives
Estella G. da Mota, Elaine F. F. da Cunha and Matheus P. Freitas
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Synthesis and Anticancer Activity of 1, 3, 5-Triaryl-1H-Pyrazole
Sajad Ghadbegi, Seyed Nasser Ostad, Abbas Shafiee and Mohsen Amini
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Anticancer Evaluation of 3,4,5,4'-trans-tetramethoxystilbene (DMU-212) and Its Analogs Against an Extensive Panel of Human Tumor Cell Lines
Nikhil Reddy Madadi and Peter A. Crooks
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Utilization of the DaT-SCAN SPECT in the Diagnosis of Parkinson's Disease in Older Subjects
Fulvio Lauretani, Livia Ruffini, Augusto Scaglioni, Carla Cidda, Chiara Guareschi, Anna Nardelli, Gian Paolo Ceda and Marcello Maggio
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In Silicoanalysis of Plasmodium Falciparum Actinand Profilin Interaction at the Interface Region for Antimalarial Design
Asrar Alam, Zahid Kamal and Atiya Fatima
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Structure, DNA Binding and Cytotoxicity Studies of [Cu(D-glu)(phen)(H2O)]•NO3•2H2O
Ling Liu, Jie Mou, Youguang Zheng, Tonghui Huang, Shuaishuai Wang and Yi Liu
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Synthetic Naphthoflavonoids Showing Inhibitory Effects on Clonogenicity against Cisplatin-Resistant A2780/Cis Human Ovarian Cancer Cells
Yearam Jung, Soon Young Shin, Yeonjoong Yong, Hyuk Yoon, Seunghyun Ahn, Hyeryoung Jung, Dongsoo Koh, Young Han Lee and Yoongho Lim
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Synthesis and Cytotoxic Activities of a Curcumin Analogue and Its Mannich Derivatives
Kadir Ozden Yerdelen, Halise Inci Gul, Hiroshi Sakagami, Naoki Umemura, Murat Sukuroglu and Halise Inci Gul
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Substrate - Inositol Transporter Interactions: Molecular Docking Study
Mariyana Atanasova and Irini Doytchinova
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Proteins as Alternate Targets of Enediynes
Hussam M. Bdour, Snigdha Roy and Amit Basak
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Syntheses of Ethyl Pyruvate’s Bioisosteres Inhibiting Inducible Nitric Oxide Production in Lipopolysaccharide-induced BV2 Cells
Ju-Young Park, Byung-Wook Kim, Soon-Jung Kwon, Dong-Kug Choi, Ja-Kyeong Lee and Sung-Hwa Yoon
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Synthesis and In vitro Evaluation of Dibenzoazepine Triazole Derivatives: A Novel Class of Antileishmanial Agents
Maria Aqeel Khan, Aliyan Saleem, Nida Ghouri, Abdul Hameed, M. Iqbal Choudhary and Fatima Z. Basha
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Preparation and Characterization of CS/(β-CD)/PAA Composite Hydrogels for Controlled Drug Delivery
Jie Ren, Xiaoci Yang, Mengqi Yao, Jinfen Gu, Xiaohua Tang and Wu Yang
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3D-QSAR Study of Flavone Derivatives as Inhibitors of HeLa Cervix Adenocarcinoma Cell Lines
Jae Cho, Somi Kim Cho and Yoongho Lim
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Synthesis and Preliminary Evaluation of Novel Bone-targeting NSAIDs Prodrugs based on Glutamic Acid Oligopeptides
Yi Zhao, Dongsheng He, Lifang Ma and Li Guo
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Identification of Potential Mps1 Inhibitors Through Multiple Pharmacophore- based Virtual Screening and Molecular Docking
Xiaoli Li, Lu Zhou, Yahui Tian and Suwen Zhou
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Design, Synthesis and Biological Evaluation of Lapatinib Derivatives as HER1/HER2 Inhibitors
Aifeng Lyu, Lei Fang, Shaohua Gou and Xia Liu
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Synthesis and In Vitro Evaluation of Furan-Based Chalcone Derivatives as Antimicrobial Agents
Ahmet Özdemir, Mehlika Dilek Altıntop, Zerrin Cantürk and ZaferAsım Kaplancıklı
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Synthesis, Antitumor of New Pyrimidineand Caffeine Derivatives
Ameen Ali Abu-Hashem and Hoda Abdel Raouf Hussein
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Design, Synthesis and AntitumorActivities of Bis-arylureas and Bisarylamides Based on 1H-benzo[d]imidazole Moiety as Novel BRaf V600E/VEGFR2 Dual Inhibitors
Weimin Yang, Yadong Chen, Yanmin Zhang, Sanzhi Tang, Hongli Chen, Weifang Tang and Tao Lu
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Synthesis and Biological Activity of Thiazole Dithiocarbamate Derivatives
Nalan Gundogdu-Karaburun
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Synthesis and Anticancer Activity of Some 2-[3/4-(2-Substituted Phenyl-2- oxoethoxy)benzylidene]-6-substituted-2,3-dihydro-1H-inden-1-one Derivatives
Nalan Gundogdu-Karaburun, Ahmet Cagri Karaburun, Seref Demirayak, Ismail Kayagil and Leyla Yurttas
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Synthesis and Biological Evaluation of New Tubulin Inhibitors: Shikonin Thio-glycoside Derivatives
Xiao-Ming Wang, Hong-Yan Lin, Jin-Liang Qi, Li-Fei Bai and Yong-Hua Yang
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Fat-Soluble Vitamins Release Based on Clinoptilolite Zeolite as an Oral Drug Delivery System
Mehdi Rahimi, Hamid Mobedi, Aliasghar Behnamghader, Alireza Nateghi Baygi, Houri Mivehchi and Esmaeil Biazar
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Synthesis and Biological Evaluations of 3-Benzothiazol-2-yl Coumarin Derivatives as MEK1 Inhibitors
Chao Wang, Fengrong Xu, Yan Niu, Yun Wu, Jing Sun, Yihong Peng, Lei Liang and Ping Xu
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Synthesis and Biological Evaluation of Arylthiourea Derivatives with Antitubercular Activity
Rusong Luo, Tuomo Laitinen, Liyan Teng, Tapio Nevalainen, Maija Lahtela-Kakkonen, Baofu Zheng, Honghai Wang, Antti Poso and Xuelian Zhang
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Synthesis and Antiproliferative Evaluation of Hybrids of Indolin-2-one and Quinazoline-4(3H)-one Linked via Imine Bond
Wei-Yao Wu, Sheng-Li Cao, Bei-Bei Mao, Ji Liao, Zhong-Feng Li, Hao-Bin Song and Xingzhi Xu
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Construction and High Expression of a Recombinant Amino-Proximal HSV-2 Glycoprotein B Polypeptide with Immunogenicity in Escherichia coli
Xu Ning, Tu Jingjing, Wang Xian Yan and Xu Fang
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Synthesis and Study of Antitumor Activity of Artimisinin Glucoside
Yanrong Ren and Guoping Chen
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Synthesis and Biological Activity of New 2,3-dihydro-1H-cyclopenta[b]- quinoline Derivatives as Acetylcholinesterase Inhibitors
Pawel Szymanski, Magdalena Markowicz, Marek Bajda, Barbara Malawska and Elzbieta Mikiciuk-Olasik
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Novel Aminoalcohol Derivatives Bearing 4-Phenylphenol as Antischistosomal Drugs
Li-Ping Duan, Jian Xue, Yi Tao and Hao-Bing Zhang
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Deformable Surfactant Vesicles Loading Ammonium Glycyrrhizinate: Characterization and In Vitro Permeation Studies
Luisa Di Marzio, Carlotta Marianecci, Federica Rinaldi, Sara Esposito and Maria Carafa
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