E-Pub Articles Ahead of Print ::: Current Pharmaceutical Design

ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)


Volume 23, 46 Issues, 2017


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Current Pharmaceutical Design

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  • 73rd of 253 in Pharmacology & Pharmacy

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Editor-in-Chief:
William A. Banks
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E-Pub Articles Ahead of Print

Oral Antiplatelet and Anticoagulant Agents in the Prevention and Management of Ischemic Stroke


Shreya Shrestha, Shannon Coy and Kimon Bekelis.


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Double-Blind, Placebo-Controlled, Randomized Phase I/IIa Study (Safety and Efficacy) with Buspirone/Levodopa/Carbidopa (SpinalonTM) in Subjects with Complete AIS A or Motor-Complete AIS B Spinal Cord Injury


Mohan Radhakrishna, Inge Steuer, François Prince, Mary Roberts, David Mongeon, Maryam Kia, Sasha Dyck, Gilbert Matte, Mario Vaillancourt and Pierre A Guertin.


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Recombinant Activated Factor VII (Eptacog Alfa Activated, NovoSeven®) in Patients with Rare Congenital Bleeding Disorders. A Systematic Review on its Use in Surgical Procedures


Matteo Nicola Dario Di Minno, Pasquale Ambrosino, Veronika A. Myasoedova, Manuela Amato, Itala Ventre, Elena Tremoli and Alessandro Di Minno.


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Hot Topics In Dry AMD


Raja Narayanan and Baruch D Kuppermann.


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Endophthalmitis Prophylaxis in Cataract Surgery: Overview of Current Practice Patterns Around the World


Andrzej Grzybowski, Stephen G. Schwartz, Kazuki Matsuura, Stephan Ong Tone, Steve Arshinoff, Jonathon Q. Ng, Jay J. Meyer, Wu Liu, Soosan Jacob, Mark Packer, Rifna Lutfiamida, Sjakon Tahija, Paul Roux, Boris Malyugin, Julio A. Urrets-Zavalia, Nicolas Crim, Evangelina Esposito, Pablo Daponte, Fernando Pellegrino, Enrique O. Graue-Hernandez, Aida Jimenez-Corona, Jorge Valdez Garcia, Julio C. Hernandez-Camarena, Nidhi Relhan, Harry W. Flynn, Jr. and Ravilla D Ravindran.


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Hot Topics in Perioperative Antibiotics for Cataract Surgery


Patrycja Kuklo, Andrzej Grzybowski, Stephen G. Schwartz, Harry W. Flynn and Avinash Pathengay.


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The Role of Rho Kinase Inhibitors in Corneal Endothelial Dysfunction


Naoki Okumura, Shigeru Kinoshita and Noriko Koizumi.


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Smoking and Eye Pathologies. A Systemic Review. Part I. Anterior Eye Segment Pathologies


Małgorzata Nita and Andrzej Grzybowski.


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New Therapeutics to Modulate Mitochondrial Function in Neurodegenerative Disorders


Heather M. Wilkins and Jill K Morris.


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Proteolytic Cleavage of Polyglutamine Disease-Causing Proteins: Revisiting the Toxic Fragment Hypothesis


Carlos A. Matos, Luís Pereira de Almeida and Clévio Nóbrega.


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Antiplatelet and Anticoagulation Therapy in Structural Heart Disease Interventions Beyond TAVI


Manolis Vavuranakis, Konstantinos Dean Boudoulas, Ourania Katsarou, Dimitrios A. Vrachatis, Konstantinos I. Kalogeras, Theodore G. Papaioannou, Gerasimos Siasos, Evangelos Oikonomou, George Lazaros, Michael-Andreas Vavuranakis, Spyridon Deftereos and Dimitrios Tousoulis.


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Microtubule-Directed Therapeutic Strategy for Neurodegenerative Disorders: Starting From the Basis and Looking on the Emergences


Graziella Cappelletti, Daniele Cartelli, Michael S. Christodoulou and Daniele Passarella.


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Role of Neurotrophic Factors in Parkinson´s Disease


Diogo Tomé, Carla Pais Fonseca, Filipa Lopes Campos and Graça Baltazar.


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Neurodegenerative Disease: A Perspective on Cell-Based Therapy In The New Era of Cell-Free Nano-Therapy


Su M. Metcalfe, Sean Bickerton and Tarek Fahmy.


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Antiplatelets and Antithrombotics in Patients with Liver Insufficiency: From Pathophysiology to Clinical Practice


Melanie Deutsch and John Koskinas.


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Theories About Blood Coagulation in the Writings of Ancient Greek Medico-philosophers


Gregory Tsoucalas, Marianna Karamanou, Theodoros G. Papaioannou and Markos Sgantzos.


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Ester-Based Hydrophilic Cyclodextrin Nanosponges for Topical Ocular Drug Delivery


Zikhona Hayiyana, Yahya Essop Choonara, Aubrey Makgotloe, Lisa Claire du Toit, Pradeep Kumar and Viness Pillay.


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Natural Approaches in Diabetes Management: A Review of Diet, Exercise, and Natural Products


William M. Schultz, Tina Varghese, Robert E. Hein, Devinder S. Dhindsa, Elliot N. Mahlof, Hannah C. Cai, Geoffrey Southmayd, Pratik B. Sandesaraa, Danny J. Eapen and Laurence S Sperling.


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Hot Topics in Pharmacogenetics of Age-Related Macular Degeneration


Stephen G. Schwartz, Milam A. Brantley, Jaclyn L. Kovach and Andrzej Grzybowski.


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Glaucoma: Hot Topics in Pharmacology


Shiama I. Balendra, Parth Arvind Shah, Mishank Jain, Andrzej Grzybowski and Maria Francesca Cordeiro.


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Photosensitizers for Photodynamic Therapy: Photochemistry in the Service of Oncology


Carsten Lange and Patrick J Bednarski.


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Structural Modifications of Diarylpyrimidine-quinolone Hybrids as Potent HIV-1 NNRTIs with an Improved Drug Resistance Profile


Tian-Qi Mao, Qiu-Qin He, Wen-Xue Chen, Gang-Feng Tang, Fen-Er Chen, Erik De Clercq, Dirk Daelemans and Christophe Pannecouque.


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Study in Treatment of Collagen-Induced Arthritis in DBA/1 Mice Model by Genistein


Peng Zhang, Yiping Hu, Jinchao Li, Ling Qin, Ye Yue, Wenxiang Cheng and Xiaohua Pan.


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Multiple Sclerosis and Neuroinflammation: The Overview of Current and Prospective Therapies


Ivana Bjelobaba, Danijela Savic and Irena Lavrnja.


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Hot Topic in Pharmacotherapy for Neovascular Age-Related Macular Degeneration


Khalil Ghasemi Falavarjani and Srinivas R Sadda.


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Perspectives on Strategies Using Swellable Polymers in Solid Dispersions for Controlled Drug Release


Thao TD Tran and Phuong HL Tran.


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MiR 221/222 as New Players in Tamoxifen Resistance


Nafiseh Sadat Alamolhodaei, Javad Behravan, Fatemeh Mosaffa and Gholamreza Karimi.


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Hot Topics in Dry Eye Disease


Pablo Alberto Chiaradia, Luis Alberto Zeman Bardeci, Sebastián Dankert, Marcos Omar Mendaro and Andrzej Grzybowski.


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Is Metformin a Perfect Drug? Updates in Pharmacokinetics and Pharmacodynamics


Magdalena Markowicz-Piasecka, Kristiina Maria Huttunen, Łukasz Mateusiak, Elżbieta Mikiciuk-Olasik and Joanna Sikora.


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Prevention and Treatment of Postoperative Endophthalmitis Using Povidone-Iodine


Hiroyuki Shimada, Hiroyuki Nakashizuka and Andrzej Grzybowski.


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Traditional and Alternative Therapies for Refractory Angina


Duygu Kocyigit, Kadri Murat Gurses, Muhammed Ulvi Yalcin and Lale Tokgozoglu.


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The Role of Chinese Herbal Medicines and Bioactive Ingredients Targeting Myocardial KCa and KATP Channels in Cardiovascular Diseases


Yan Dong, Pengqian Wang, Xue Feng, Bing Li, Zhong Wang and Haixia Li.


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Peroxisome Proliferator-Activated Receptor (PPAR) Gamma Agonists as Therapeutic Agents for Cardiovascular Disorders: Focus on Atherosclerosis


Ekaterina A. Ivanova, Veronika A. Myasoedova, Alexandra A. Melnichenko and Alexander N Orekhov.


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Translational Applications of Tissue Engineering in Cardiovascular Medicine


Arin Dogan, Eser Elçin and Y Murat Elçin.


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Targeting the Hedgehog Pathway for Locally Advanced and Metastatic Basal Cell Carcinoma


Vivian T. Yin and Bita Esmaeli.


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DARPins Bioengineering and its Theranostic Approaches: Emerging Trends in Protein Engineering


Mahmood Rasool, Arif Malik, Mubashir Hussain, Kalsoom A. Haq, Kiran Butt, Abdul Basit, Muhammad Imran Naseer, Muhammad Asif, Rozena Shaikh, Mohammad Zahid Mustafa, Qamre Alam, Ghulam Rasool, Waseem Ahmad, Absarul l Haque and Mohammad Amjad Kamal.


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Research Advances in Molecular Modeling in Cyclodextrins


Qianqian Zhao, Weixiang Zhang, Runmiao Wang, Yitao Wang and Defang Ouyang.


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Membrane Bioreactors for Pharmaceutical Applications: Optically Pure Enantiomers Production


Emma Piacentini, Rosalinda Mazzei and Lidietta Giorno.


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Antihypertensive Treatments In Patients Affected By Aortic Valve Stenosis


Paolo Poggio, Gianluca Folesani, Giuseppe M. Raffa, Paola Songia, Vincenzo Valenti, Veronika Myasoedova and Alessandro Parolari.


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MtDNA Damage Associated with Mitochondrial Cytopathies


Anastasia I. Ryzhkova, Margarita A. Sazonova, Vasily V. Sinyov, Elena V. Galitsyna, Mariуa M. Chicheva, Alexandra A. Melnichenko, Zukhra B. Khasanova, Andrey V. Zhelankin, Konstantin Y. Mitrofanov, Anton Yu. Postnov, Alexander N. Orekhov and Igor A Sobenin.


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Cybrid Models of Pathological Cell Processes in Different Diseases


Margarita A. Sazonova, Vasily V. Sinyov, Anastasia I. Ryzhkova, Elena V. Galitsyna, Tatiana P. Shkurat, Alexandra A. Melnichenko, Natalya A. Demakova, Anton Yu. Postnov, Igor A. Sobenin and Alexander N Orekhov.


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Drug Carrier Systems Based On Cyclodextrin Supramolecular Assemblies And Polymers: Present And Perspectives


Gustavo González-Gaitano, José Ramón Isasi, Itziar Vélaz and Arantza Zornoza.


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Polymer-Based Novel Lung Targeted Delivery Systems


Enas Elmowafy, Rihab Osman and Rania AH Ishak.


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Core-shell Semiconductor Nanocrystals: Effect of Composition, Size, Surface Coatings on Their Optical Properties, Toxicity, and Pharmacokinetics


Wafa` T Al-Jamal.


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Reversal Agents for Oral Antiplatelet and Anticoagulant Treatment During Bleeding Events: Current Strategies


Peter Raimondi, Elaine M. Hylek and Konstantinos N Aronis.


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Dropless Cataract Surgery: An Overview


Richard L. Lindstrom, M. Stewart Galloway, Andrzej Grzybowski and Jeffrey T Liegner.


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Therapeutic Potential of Drugs Targeting Pathophysiology of Intracerebral Hemorrhage: From Animal Models to Clinical Applications


Kuo-Hsing Liao, Chih-Wei Sung, Ya-Ni Huang, Wei-Jiun Li, Po-Chuan Yu and Jia-Yi Wang.


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Natural Products with Antiplatelet Action


Gabriela Elisa Hirsch, Paulo Ricardo Nazário Viecili, Amanda Spring de Almeida, Sabrina Nascimento, Fernando Garcez Porto, Juliana Otero, Aline Schmidt, Brenda da Silva, Mariana Migliorini Parisi and Jonatas Zeni Klafke.


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Therapeutic Suppression of Nonsense Mutation: An Emerging Target in Multiple Diseases and Thrombotic Disorders


Md. Asiful Islam, Fahmida Alam, Mohammad Amjad Kamal, Siew Hua Gan, Kah Keng Wong and Teguh Haryo Sasongko.


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PI3K/Akt/mTOR Intracellular Pathway and Breast Cancer: Factors, Mechanism and Regulation


Var Ruchi Sharma, Girish Kumar Gupta, A.K. Sharma, Navneet Batra, Daljit K. Sharma, Amit Joshi and Anil K Sharma.


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Gymnema sylvestre for Diabetes: From Traditional Herb to Future’s Therapeutic


Pragya Tiwari, Khurshid Ahmad and Mohammad Hassan Baig.


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The Underestimated Role of Mechanical Stimuli in Brain Diseases and the Related In Vitro Models


Tingwang Guo, Peng Ren, Shilei Hao and Bochu Wang.


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A Review on Injury Mechanism of Intracerebral Hemorrhage in Vehicle Accidents


Fan Li, Honggeng Li, Zhi Xiao, Ronggui Lu, Zhiteng Zhang, Haiyun Zhu and Lihai Ren.


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Injectable Drug-Loaded Nanocarriers for Lung Cancer Treatments


Huang-Ping Yu, Ibrahim A. Aljuffali and Jia-You Fang.


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Epidemiology, Prognosis and Prevention of Non-Traumatic Intracerebral Hemorrhage


Christian Weimar and Julian Kleine-Borgmann.


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Targeting Vascular Neural Network in Intracerebral Hemorrhage


Yi Yin, Hongfei Ge, John H. Zhang and Hua Feng.


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Brain Drug Delivery Systems for the Stroke Intervention and Recovery


Tiantian Luo, Ju Wang, Shilei Hao, Tingwang Guo, Peng Ren, Zhongjun Cheng, Feiyan Gao, Yuhua Gong and Bochu Wang.


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From PK/PD to QSP: Understanding the Dynamic Effect of Cholesterol-Lowering Drugs on Atherosclerosis Progression and Stratified Medicine


Cesar Pichardo-Almarza and Vanessa Diaz-Zuccarini.


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Liposomes For Pulmonary Drug Delivery: The role of Formulation and Inhalation Device Design


Abdelbary Elhissi.


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Targeting the Nrf2-Heme Oxygenase-1 Axis after Intracerebral Hemorrhage


Jing Chen-Roetling and Raymond F Regan.


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Amorphous and Crystalline Particulates: Challenges and Perspectives in Drug Delivery


Hisham Al-Obaidi, Mridul Majumder and Fiza Bari.


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Cell-Free Circulating Epigenomic Signatures: Non-Invasive Biomarker for Cardiovascular and Other Age-Related Chronic Diseases


Arpit Bhargava, Naveen Kumar Khare, Neha Bunkar, Koel Chaudhury, Kailash Chand Pandey, Subodh Kumar Jain and Pradyumna Kumar Mishra.


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Polymer Nanoparticles as Smart Carriers for the Enhanced Release of Therapeutic Agents to the CNS


Mariacristina Gagliardi and Claudia Borri.


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Separation of Biologically Active Compounds by Membrane Operations


Xiaoying Zhu and Renbi Bai.


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HDL-Targeting Therapeutics: Past, Present and Future


Emile Zakiev, Ma Feng, Vasily Sukhorukov and Anatol Kontush.


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Exploring the Role of Nanoparticles in Amphotericin B Delivery


Soraia Zaioncz, Najeh Maissar Khalil and Rubiana Mara Mainardes.


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Editorial: Discovery and Validation of Drug Targets Through Human Genetics and Epigenetics


Karmen Stankov.


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María José Torres.


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Editorial: Towards the Integration of Quantitative and Systems Pharmacology into Drug Discovery: a Systems Level Understanding of Therapeutic and Toxic Effects of Drugs


Violeta I Pérez Nueno.


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Mesoporous Silica Molecular Sieve Based Nanocarriers: Transpiring Drug Dissolution Research


Satyanarayan Pattnaik and Kamla Pathak.


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Transferrin-Conjugated Nanocarriers as Active-Targeted Drug Delivery Platforms for Cancer Therapy


Daniele R. Nogueira-Librelotto, Cristiane F. Codevilla, Ammad Farooqi and Clarice M B Rolim.


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Stimuli-Responsive Capsule Membranes for Controlled Release in Pharmaceutical Applications


Zhuang Liu, Xiao-Jie Ju, Wei Wang, Rui Xie, Lu Jiang, Qianming Chen, Yan-Qiong Zhang, Jiang-Feng Wu and Liang-Yin Chu.


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Biohybrid Membrane Systems And Bioreactors As Tools For In Vitro Drug Testing


Simona Salerno and Loredana De Bartolo.


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Membrane-based Technologies in the Pharmaceutical Industry and Continuous Production of Polymer-coated Crystals/Particles


Dengyue Chen, Kamalesh K. Sirkar, Chi Jin, Dhananjay Singh and Robert Pfeffer.


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Molecularly Engineered Polymer-Based Systems in Drug Delivery and Regenerative Medicine


Susanna Piluso, Al Halifa Soultan and Jennifer Patterson.


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Concentration and Fractionation of Polyphenols by Membrane Operations


Bartosz Tylkowski, Martyna Nowak, Irene Tsibranska, Anna Trojanowska, Łukasz Marciniak, Ricard Garcia Valls, Tania Gumi, Marta Giamberini and Renata Jastrząb.


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Estradiol Uptake in a Combined Magnetic Ion Exchange - Ultrafiltration (MIEX-UF) Process During Water Treatment


Alessandra Imbrogno, Jennifer Biscarat and Andrea Iris Schäfer.


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PPAR Agonists, Atherogenic Dyslipidemia and Cardiovascular Risk


Dragana Nikolic, Giuseppa Castellino, Maciej Banach, Peter P. Toth, Ekaterina Ivanova, Alexander N. Orekhov, Giuseppe Montalto and Manfredi Rizzo.


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Medicinal Plants with Multiple Effects on Cardiovascular Diseases: A Systematic Review


Hojjat Rouhi-Boroujeni, Esfandiar Heidarian, Hamid Rouhi-Boroujeni, Fatemeh Deris and Mahmoud Rafieian-Kopaei.


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An Umbrella Review of Nuts Intake and Risk of Cardiovascualr Disease


Lukas Schwingshackl, Georg Hoffmann, Benjamin Missbach, Marta Stelmach-Mardas and Heiner Boeing.


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Complementary Role of Herbal Medicine and Exercise in Cardiovascular Disease Prevention and Management: A Review of Evidence


Sundar Kumar Veluswamy, Abraham Samuel Babu and Lakshmi Manickavasagam Sundar.


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Garlic for Cardiovascular Disease: Prevention or Treatment?


Feras Q. Alali, Tamam El-Elimat, Lila Khalid, Reema Hudaib, Tuqa Saleh Al-Shehabi and Ali H Eid.


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Effect of Sibutramine on Plasma C-Reactive Protein, Leptin and Adiponectin Concentrations: A Systematic Review and Meta-Analysis of Randomized Controlled Trials


Antonio De Vincentis, Claudio Pedone, Umberto Vespasiani-Gentilucci, Antonio Picardi, Giuseppe Derosa, Pamela Maffioli and Amirhosssein Sahebkar.


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The Insular Cortex and Takotsubo Cardiomyopathy


Michiaki Nagai, Keigo Dote, Masaya Kato, Shota Sasaki, Noboru Oda, Eisuke Kagawa, Yoshinori Nakano, Aya Yamane, Tasuku Higashihara, Shunsuke Miyauchi, Akane Tsuchiya, Wakako Harada and Kazuomi Kario.


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Precision Medicine and a Patient-Orientated Approach: Is this the Future for Tracking Cardiovascular Disorders


Etheresia Pretorius.


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Therapeutic Interventions for Advanced Glycation-End Products and its Receptor- Mediated Cardiovascular Disease


Kailash Prasad and Shuchita Tiwari.


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Therapeutic Potential of Phytochemicals in Combination with Drugs for Cardiovascular Disorders


James Zheng Shen, Ting Long Jacky Ng and Wing Shing Ho.


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Impact of Statin Therapy on Plasma Vitamin D Levels: A Systematic Review and Meta-Analysis


Amirhossein Sahebkar, Željko Reiner, Luis E. Simental-Mendía, Gianna Ferretti, Claudia Della Corte and Valerio Nobili.


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Polymeric Nanomaterials as Nanomembrane Entities for Biomolecule and Drug Delivery


Airama Albisa, Laura Español, Martin Prieto and Victor Sebastian.


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Spices: Therapeutic Potential In Cardiovascular Health


Subha Rastogi, Madan Mohan Pandey and AKS Rawat.


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The Role of Biologically Active Ingredients from Chinese Herbal Medicines in the Regulation of Autophagy in Treating Cardiovascular Diseases and Other Chronic Diseases


Jie Li, Yonghong Gao, Xiaomeng Ren, Yanda Li, Lijun Wu, Xinyu Yang, Jie Wang, Hongcai Shang, Xingjiang Xiong and Yanwei Xing.


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Pomegranate Consumption and Blood Pressure: A Review


Sedigheh Asgary, Mahtab Keshvari, Amirhossein Sahebkar and Nizal Sarrafzadegan.


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Convenient, Traditional and Alternative Therapies for Cardiovascular Disorders


Mohammad M. Zarshenas, Arman Zargaran and Michael Blaschke.


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Adonis sp., Convallaria sp., Strophanthus sp., Thevetia sp., and Leonurus sp. - Cardiotonic plants with known traditional use and a few preclinical and clinical studies


Ilkay Erdogan Orhan, Alper Gokbulut and F Sezer Senol.


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Is There a Role for Curcumin Supplementation in the Treatment of Non-Alcoholic Fatty Liver Disease? The Data Suggest Yes


Narges Amel Zabihi, Matteo Pirro, Thomas P. Johnston and Amirhossein Sahebkar.


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Current Trends in Drug Sensitivity Prediction


Isidro Cortés-Ciriano, Lewis H. Mervin and Andreas Bender.


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A Review on the Pharmacology and Toxicology of Steviol Glycosides Extracted from Stevia rebaudiana


Amir Abbas Momtazi-Borojeni, Seyed-Alireza Esmaeili, Elham Abdollahi and Amirhossein Sahebkar.


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Epigenetically active drugs inhibiting DNA methylation and histone deacetylation


Dimitry A. Chistiakov, Veronika A. Myasoedova, Alexander N. Orekhov and Yuri V Bobryshev.


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Mutations of Mitochondrial DNA in Chronic Non-Inflammatory Diseases: Target Candidates for Treatment


Elena V. Galitsyna, Margarita A. Sazonova, Tatiana P. Shkurat, Natalya A. Demakova, Alexsandra A. Melnichenko, Vasily V. Sinyov, Anastasia I. Ryzhkova, Konstantin Y. Mitrofanov, Andrey V. Zhelankin, Igor A. Sobenin and Alexander N Orekhov.


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Medicinal plants for the treatment of asthma: A Traditional Persian Medicine perspective


Behjat Javadi, Amirhossein Sahebkar and Seyed Ahmad Emami.


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Sulfur Mustard-Induced Ocular Injuries: Update on Mechanisms and Management


Yunes Panahi, Danial Roshandel, Mohammad Mehdi Sadoughi, Mostafa Ghanei and Amirhossein Sahebkar.


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Ginseng in Dermatology: A Review


Sarvenaz Sabouri-Rad, Sara Sabouri-Rad, Amirhossein Sahebkar and Zahra Tayarani-Najaran.


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Phytochemicals Against Advanced Glycation End Products (AGEs) and the Receptor System


Sho-ichi Yamagishi, Takanori Matsui, Yuji Ishibashi, Fumiyuki Isami, Yumi Abe, Tatsuya Sakaguchi and Yuichiro Higashimoto.


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Propagation on Molecular Interaction Networks: Prediction of Effective Drug Combinations and Biomarkers in Cancer Treatment


Balázs Ligeti, Ottilia Menyhárt, Ingrid Petrič, Balázs Győrffy and Sándor Pongor.


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Sialidases: Therapeutic And Antiatherogenic Potential


VN Sukhorukov, VP Karagodin, ER Zakiev and AN Orekhov.


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Cellular and Molecular Mechanisms of Diuretic Plants: An Overview


Francislaine Aparecida Lívero, Jacqueline Vergutz Menetrier, Emerson Luiz Botelho Lourenço and Arquimedes Gasparotto Junior.


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Targeting obesity for the prevention of chronic cardiovascular disease through gut microbiota-herb interactions: An opportunity for traditional herbs


Feng Chen, Jun Jiang, Dan-Dan Tian, Qi Wen, Yong-Hui Li, Jun-Qing Zhang, Chen Cheng and Tengfei Wang.


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Mutations of Nuclear and Mitochondrial Genomes as Potential Targets for the Treatment of Metabolic Syndrome


Elena V. Galitsyna, Andrey V. Zhelankin, Igor A. Sobenin and Alexander N Orekhov.


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Outcomes With Dronedarone In Atrial Fibrillation: What Differences Between Real-World Practice And Trials? A Meta-Analysis And Meta-Regression Analysis


Igor Diemberger, Giulia Massaro, Maria Letizia Bacchi Reggiani, Stefano Lorenzetti, Mauro Biffi, Matteo Ziacchi, Cristian Martignani and Giuseppe Boriani.


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Bile Acids as Novel Pharmacological Agents: the Interplay between Gene Polymorphisms, Epigenetic Factors and Drug Response


Nebojša Pavlović, Bojan Stanimirov and Momir Mikov.


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Bona fide targets of deregulated microRNAs in non-small cell lung cancer as tool to identify novel therapeutic targets. A review


Monica Cipollini, Stefano Landi and Federica Gemignani.


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Predictive Biomarkers for Linking Disease Pathology and Drug Effect


Bernd Mayer, Andreas Heinzel, Arno Lukas and Paul Perco.


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Casein kinase II (CK2) as a therapeutic target for hematological malignancies


Chandrika Gowda, Mansi Sachdev, Sunil Muthisami, Malika Kapadia, Lidija Petrovic-Dovat, Melanie Hartman, Yali Ding, Chunhua Song, Jonathon L. Payne, Bi-Hua Tan and Sinisa Dovat.


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Hedgehog Signaling Pathway as Genetic and Epigenetic Target in Ovarian Tumors


Sonja Levanat, Maja Sabol, Vesna Musani, Petar Ozretić and Diana Trnski.


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Targeting Signalling Pathways in Hepatocellular carcinoma


Kaja Blagotinšek and Damjana Rozman.


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Targeting Notch as a Therapeutic Approach for Human Malignancies


Platonova Natalia, Lesma Elena, Basile Andrea, Bignotto Monica, Garavelli Silvia, Palano Maria Teresa, Moschini Adriana, Neri Antonino, Colombo Michela and Chiaramonte Raffaella.


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Salvia Miltiorrhiza: A Potential Red Light to the Development of Cardiovascular Diseases


Lili Wang, Rufeng Ma, Chenyue Liu, Haixia Liu, Ruyuan Zhu, Shuzhen Guo, Minke Tang, Yu Li, Jianzhao Niu, Min Fu, Sihua Gao and Dongwei Zhang.


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A brief review of blue- and bilberries’ potential to curb cardio-metabolic perturbations: Focus on diabetes


M. Carmen Crespo and Francesco Visioli.


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Cardiovascular Toxicity of Cyclooxygenase Inhibitors and Promising Natural Substitutes


Mahmoud Bahmani, Amir Sarrafchi, Hedayatollah Shirzad, Sedigheh Asgari and Mahmoud Rafieian-Kopaei.


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Systems toxicology: Systematic Approach to Predict Toxicity


Narsis A. Kiani, Ming-Mei Shang and Jesper Tegnér.


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Genetic and Epigenetic Drug Targets in Myelodysplastic Syndromes


Karmen Stankov, Sunčica Stankov and Jasmina Katanić.


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RNF5, DAB2 and Friends: Novel Drug Targets for Cystic Fibrosis


Elvira Sondo, Emanuela Pesce, Valeria Tomati, Monica Marini and Nicoletta Pedemonte.


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