E-Pub Articles Ahead of Print ::: CNS & Neurological Disorders - Drug Targets

ISSN: 1996-3181 (Online)
ISSN: 1871-5273 (Print)


Volume 16, 10 Issues, 2017


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CNS & Neurological Disorders - Drug Targets

Formerly: Current Drug Targets - CNS & Neurological Disorders

This journal supports open access

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Editor-in-Chief:
Stephen D. Skaper
Department of Pharmaceutical and Pharmacological Sciences
University of Padova
Padova
Italy


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Articles Ahead of Print

The TLR9 Antagonist iCpG-ODN at Different Dosages Inhibits Cerebral Ischemia/Reperfusion Injury in Mice


Ying Zhou, Jingrui Pan, Qingxia Peng, Zhaofei Dong Dong, Lingna Deng Deng and Yidong Wang.


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Alzheimer’s Disease and the Routine Clinical Use of CSF Biomarkers


Alessandro Martorana.


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Inhibition of Butyrylcholinesterase with Fluorobenzylcymserine, An Experimental Alzheimer’s Drug Candidate: Validation of Enzoinformatics Results by Classical and Innovative Enzyme Kinetic Analyses


Mohammad Amjad Kamal, Shazi Shakil, Muhammad S. Nawaz, Qian-sheng Yu, Harold W. Holloway, Y Tan, Xianqin Qu and Nigel H Greig.


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COMMENTARY: Transcranial Magnetic Stimulation in Multiple Sclerosis: A Method to Improve Movement


, Francisco Javier Medina-Fernández, Begoña Escribano and Isaac Túnez.





Monoamine Oxidase B Inhibitors in Parkinson's Disease


Livia Dézsi and László Vécsei.


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Increase Signaling of Wnt/β-Catenin Pathway and Presence of Apoptosis in Cerebellum of Kindled Rats


Carmen Rubio-Osornio, Artemio Rosiles-Abonce, Cristina Trejo-Solís, Moisés Rubio-Osornio, Cesar Mendoza, Verónica Custodio, Juan Carlos Martínez-Lazcano, Edith González and Carlos Paz.


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Axotomy Leads to Reduced Calcium Increase and Earlier Termination of CCL2 Release in Spinal Motoneurons with Upregulated Parvalbumin Followed by Decreased Neighboring Microglial Activation


Melinda Paizs, Roland Patai, Jozsef Engelhardt, Zoya Katarova, Izabella Obal and Laszlo Siklos.


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The Interplay between Cofilin and Phospho-Cofilin: Its Role in Maintaining Blood Brain Barrier Integrity


Qasim Alhadidi, Muhammad Shahdaat Bin Sayeed and Zahoor Shah.


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Advanced Structure-Activity Relationships Applied to Mentha spicata L. Subsp. spicata Essential Oil Compounds as AChE and NMDA Ligands, in Comparison with Donepezil, Galantamine and Memantine – New Approach in Brain Disorders Pharmacology


Speranta Avram, Mernea Maria, Eyup Bagci, Lucian Hritcu, Livia-Cristina Borcan and Dan Mihailescu.


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Synaptic Plasticity, Dementia and Alzheimer Disease


Pietro Giusti, Stephen D. Skaper, Laura Facci and Morena Zusso.


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Preventive and Protective Roles of Dietary Nrf2 Activators Against Central Nervous System Diseases


Yang Sun, Tuo Yang, Rehana K Leak, Jun-He Chen and Feng Zhang.


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Cerebrospinal-fluid Alzheimer’s Disease Biomarkers and Blood-Brain Barrier Integrity in a Natural Population of Cognitive Intact Parkinson’s Disease Patients


Claudio Liguori, Enrica Olivola, Mariangela Pierantozzi, Rocco Cerroni, Salvatore Galati, Valentina Saviozzi, Nicola Biagio Mercuri and Alessandro Stefani.


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Neuropathic Pain and Lung Delivery of Nanoparticulate Drugs: An Emerging Novel Therapeutic Strategy


Nazrul Islam, Muzaffar Abbas and Shafiqur Rahman.


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Desmoteplase for Acute Ischemic Stroke: A Systematic Review and Meta-analysis of RCTs


Ahmed Elmaraezy, Abdelrahman Ibrahim Abushouk, Soha Saad, Moutaz Eltoomy, Osama Mahmoud, Hossam Mahmoud Hassan, Ahmed Aboelmakarem, Ahmed Aboel fotoh, Farah Althaher, Nguyen Tien Huy and Kenji Hirayama.


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The Resting-State Functional Connectivity of the Default Mode Networks in Patients With Obstructive Sleep Apnea-Hypopnea Syndrome


Ting Chen, Ming Yang, Bin Liu, Yu-ting Liu, Hui-xin Zhang, Chuan-chuan Liu, Yue Zhu, Zhi-chun Huang and Ti-fei Yuan.


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Subacute Fluoxetine Reduces Signs of Hippocampal Damage Induced by a Single Convulsant Dose of 4-Aminopyridine in Rats


Ahmed Anis Shiha, Rubén Fernández de la Rosa, Mercedes Delgado, Miguel Angel Pozo and Luis García-García.


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How Immune-inflammatory Processes Link CNS and Psychiatric Disorders: Classification and Treatment Implications


George Anderson and Michael Maes.


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The Sphingosine 1-Phosphate Signaling Pathway in Epilepsy: A Possible Role for the Immunomodulator Drug Fingolimod in Epilepsy Treatment


Antonio Leo, Rita Citraro, Rosario Marra, Ernesto Palma, Eugenio Donato Di Paola, Andrew Constanti, Giovambattista De Sarro and Emilio Russo.


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Caffeine; the Forgotten Potential for Parkinson's Disease


Ahmed Negida, Mohamed Elfil, Attia Attia, Eslam Farahat, Mohamed Gabr, Ahmed Essam, Hussein Ahmed and Doaa Attia.


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Securinine Derivatives as Potential Anti-amyloid Therapeutic Approach


Margarita E. Neganova, Sergei G. Klochkov, Ludmila N. Petrova, Elena Shevtsova, Svetlana V. Afanasieva, Ekaterina S. Chudinova, Vladimir P. Fisenko, Sergei O. Bachurin, George E. Barreto and Gjumrakch Aliev.


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Neurotrophin Receptor Signaling as a Therapeutic Target for Huntington’s Disease


Danielle A. Simmons, Frank M. Longo and Stephen M Massa.


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Heat Shock Proteins: Old and Novel Roles in Neurodegenerative Diseases in the Central Nervous System


Johannes M. van Noort, Marianna Bugiani and Sandra Amor.


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The Positive Synergism of CPT and MK-801 in Behavioral Tests and in Reduction of Environmental Stress and Redox Signaling Changes in Mice Cerebral Cortex


Mariola Herbet, Aleksandra Szopa, Sylwia Wośko, Anna Serefko, Magdalena Izdebska, Monika Gawrońska-Grzywacz, Iwona Piątkowska-Chmiel, Martyna Janas, Renata Gieroba, Agnieszka Korga, Ewa Poleszak and Jarosław Dudka.


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Treatment possibilities for psychosis in Parkinson’s disease with an emphasis on the newly approved drug: Pimavanserin


Zsófia Majláth, Izabella Obál and László Vécsei.


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Purinergic Signalling and Neurological Diseases: An Update


Geoffrey Burnstock.


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Curcumin Suppresses Tumor Growth and Angiogenesis in Human Glioma Cells Through Modulation of Vascular Endothelial Growth Factor/ Angiopoietin-2/Thrombospondin-1 Signaling


Zhiqiang Zhang, Cong Li, Qijia Tan, Caijun Xie, Yanying Yang, Wengang Zhan, Fu Han, Hari Shanker Sharma and Aruna Sharma.


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Lithium Restores Age Related Olfactory Impairment in the Ts65Dn Mouse Model of Down Syndrome


Sandra Guidi, Patrizia Bianchi, Fiorenza Stagni, Andrea Giacomini, Marco Emili, Stefania Trazzi, Elisabetta Ciani and Renata Bartesaghi.


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Metabotropic Glutamate Receptor 7 (mGluR7) as a Target for the Modulating Pain-Evoked Activities of Neurons in the Hippocampal CA3 Region of Rats


Xinya Wei, Dongxiao Yang, Tiefeng Shi, Jianing Wang, Yunling Deng, Xuezhu Qiao, Chunxiao Yang and Man-Ying Xu.


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The Protective Effect of Jatrorrhizine against Oxidative Stress in Primary Rat Cortical Neurons


Tao Luo, Xiuyin Shen, Sheng Li, Ting Ouyang and Huaqiao Wang.


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Every Cloud Has a Silver Lining: Proneurogenic Effects of Aβ Oligomers and HMGB-1 via Activation of the RAGE-NF-κB Axis


Valeria Bortolotto and Mariagrazia Grilli.


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