E-Pub Articles Ahead of Print ::: CNS & Neurological Disorders - Drug Targets

ISSN: 1996-3181 (Online)
ISSN: 1871-5273 (Print)

Volume 16, 10 Issues, 2017

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CNS & Neurological Disorders - Drug Targets

Formerly: Current Drug Targets - CNS & Neurological Disorders

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Stephen D. Skaper
Department of Pharmaceutical and Pharmacological Sciences
University of Padova

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Articles Ahead of Print

Involvement of microRNA-146a in the Inflammatory Response of Status Epilepticus Rats

Qiong Luo, Linlin Zhu, Zhen Ren, Yiye Shao, Yangmei Xie, Yonghao Feng, Bing Li and Yinghui Chen.

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Differential Mechanisms Underlying Antidepressant Responses of Ketamine and Imipramine

Zhisheng Wei, Ke Zhang, Qinji Zhou, Mingfa Huang, Ting Xu, Jianyang Dong, Yu Zheng and Xiang Cai.

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C-Abl Inhibition; A Novel Therapeutic Target for Parkinson’s Disease

Abdelrahman Ibrahim Abushouk, Ahmed Negida, Rasha Abdelsalam Elshenawy, Hossam Zein, Ali M Hammad, Ahmed Menshawy and Wael MY Mohamed.

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Obesity and Metabolic Syndrome Affect the Cholinergic Transmission and Cognitive Functions

Martinelli Ilenia , Tomassoni Daniele, Moruzzi Michele, Traini Enea and Seyed Khosrow Tayebati.

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Brain-derived Neurotrophic Factor Promotes Growth of Neurons and Neural Stem Cells Possibly by Triggering the Phosphoinositide 3-kinase/ AKT/Glycogen Synthase Kinase-3β /β-catenin Pathway

Jin-wei Yang, Zhang Liang, Shi-kang Deng, Deng, Wei Ma, Xian-bin Wang, Xing-tong Li, Tong-tong Wang, Yun-fei Dai, Jian-hui Guo and Li-yan Li.

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Book Review:“Dendrites- Third Edition”

Gislaine Z Réus.

Mitochondrial Permeability Transition Pore as a Suitable Target for Neuroprotective Agents Against Alzheimer Disease

Elena F. Shevtsova, Daria Vinogradova, Margarita E. Neganova, Marco Avila-Rodriguez, G Md Ashraf , George E. Barreto, Sergey O. Bachurin and Gjumrakch Aliev.

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Cannabis: A Neurological Remedy or a Drug of Abuse in India

Pronit Biswas, Pooja Mishra, Devasish Bose and Abhilasha Durgbanshi.

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Recalling Memory by Brain Stimulation


Let the Time Fly: Dopamine is the Arbiter

Xiaodong Liu, Changzheng Zhang, Oscar Arias-Carrion and Ti-Fei Yuan.

Dendrites, 3rd Edition

M Foster Olive.

Research Highlights BAY 1436032: A Novel Pan-mutant IDH1 Inhibitor Extends Survival of Mice with Experimental Brain Tumors

S. Gokul and G K Rajanikant.

Neuroprotective Effects of Citrus Fruit-Derived Flavonoids, Nobiletin and Tangeretin in Alzheimer’s and Parkinson’s Disease

Nady Braidy, Sahar Behzad, Solomon Habtemariam, Touqeer Ahmed, Maria Daglia, Seyed Mohammad Nabavi, Eduardo Sobarzo-Sanchez and Seyed Fazel Nabavi.

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Synthetic Cannabinoids: Psychopharmacology, Clinical Aspects, and Psychotic Onset

Giovanni Martinotti, Rita Santacroce, Duccio Papanti, Yasmine Elgharably, Mariya Prilutskaya and Ornella Corazza.

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Dopaminergic Modulation of Sleep–Wake States

Andrea Herrera-Solís, Wendy Herrera-Morales, Luis Núñez-Jaramillo and Oscar Arias-Carrión.

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Immune System Modulators with Antidepressant Effects: Evidence from Animal Models

Helena M. Abelaira, Amanda L. Maciel, João Quevedo and Gislaine Z Réus.

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Abnormalities in Kynurenine Pathway Metabolism in Treatment-Resistant Depression and Suicidality: A Systematic Review

Gianluca Serafini, Giulia Adavastro, Giovanna Canepa, Laura Capobianco, Claudia Conigliaro, Federica Pittaluga, Martino Belvederi Murri, Alessandro Valchera, Domenico De Berardis, Maurizio Pompili, Daniel Lindqvist, Lena Brundin and Mario Amore.

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Cannabis; Epidemiological, Neurobiological and Psychopathological Issues: An Update

Maria Antonietta De Luca, Gaetano Di Chiara, Cristina Cadoni, Daniele Lecca, Laura Orsolini, Duccio Papanti, John Corkery and Fabrizio Schifano.

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Elevated C-Reactive Protein Levels in Women with Bipolar Disorder May be Explained by a History of Childhood Trauma, Especially Sexual Abuse, Body Mass Index, and Age

Juliana Brum Moraes, Michael Maes, Decio Sabbatini Barbosa, Thais Zagabria Ferrari, Marcela Keikko Spagolla Uehara, André F. Carvalho and Sandra Odebrecht Vargas Nunes.

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Neurocognitive Correlates in Driving Under the Influence of Cannabis

Francesco Paolo Busardò, Manuela Pellegrini, Julia Klein and Natale Mario di Luca.

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Concurrent Use of Cannabis and Alcohol: Neuropsychiatric Effects and Consequences

Anna Romaguera, Marta Torrens, Esther Papaseit, Ana Lucia Arellano and Magi Farré.

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Neurological Disorders in Medical Use Of Cannabis: An Update

Renata Solimini, Maria Concetta Rotolo, Simona Pichini and Roberta Pacifici.

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Neuropsychiatric and General Interactions of Natural and Synthetic Cannabinoids with Drugs of Abuse and Medicines

Ana Lucia Arellano, Esther Papaseit, Anna Romaguera, Marta Torrens and Magi Farré.

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Is There a Teratogenicity Risk Associated with Cannabis and Synthetic Cannabimimetics’ (’Spice’) Intake?

Laura Orsolini, Duccio Papanti, John Corkery, Maria Antonietta De Luca, Cristina Cadoni, Gaetano Di Chiara and Fabrizio Schifano.

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Ultra-Micronized Palmitoylethanolamide: An Efficacious Adjuvant Therapy for Parkinson’s Disease

Stefania Brotini, Carlo Schievano and Leonello Guidi.

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Neurological Aspects of Medical Use of Cannabidiol

Carmen Mannucci, Michele Navarra, Fabrizio Calapai, Elvira Ventura Spagnolo, Francesco Paolo Busardò, Roberto Da Cas, Francesca Menniti Ippolito and Gioacchino Calapai.

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Therapeutic Role of Synaptic Vesicle Glycoprotein 2A (SV2A) in Modulating Epileptogenesis

Yukihiro Ohno and Kentaro Tokudome.

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IgA/IgM Responses to Gram-Negative Bacteria are not Associated with Perinatal Depression, but with Physio-Somatic Symptoms and Activation of the Tryptophan Catabolite Pathway at the End of Term and Postnatal Anxiety

Roomruangwong Chutima, Buranee Kanchanatawan, Sunee Sirivichayakul, George Anderson, André F. Carvalho, Sebastien Duleu, Michel Geffard and Michael Maes.

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The Effect of Pyrroloquinoline Quinone on Apoptosis and Autophagy in Traumatic Brain Injury

Pengju Zhang, Yongqi Ye, Yuhang Qian, Baoxin Yin, Jianmei Zhao, Shunxin Zhu, Li Zhang and Meijuan Yan.

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Utilizing Delta Opioid Receptors and Peptides for Cytoprotection: Implications in Stroke and Other Neurological Disorders

Marci G. Crowley, M. Grant Liska, Trenton Lippert, Sydney Coreya and Cesar V Borlongan.

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The Endocannabinoid System Modulating Levels of Consciousness, Emotions and Likely Dream Contents

Eric Murillo-Rodriguez, José Carlos Pastrana-Trejo, Mireille Salas-Crisóstomo and Miriel de-la-Cruz.

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Granulocyte Colony-Stimulating Factor Attenuates Blood-Brain Barrier Damage and Improves Cognitive Function in Spontaneously Hypertensive Rats

Xin Wei, Yan Xu, Yanling Jin, Hongliang Feng and Shouquan Dong.

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Further Evaluation of Mechanisms Associated with the Antidepressantlike Signature of Scopolamine in Mice

Anna E. Martin, Douglas A. Schober, Alexander Nikolayev, Vladimir V. Tolstikov, Wesley H. Anderson, Richard E. Higgs, Ming-Shang Kuo, Anastasia Laksmanan, John T. Catlow, Xia Li, Christian C. Felder and Jeffrey M Witkin.

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Parkinson’s Disease is Accompanied by Intertwined Alterations in Iron Metabolism and Activated Immune-inflammatory and Oxidative Stress Pathways

Carine Coneglian de Farias, Michael Maes, Kamila Landucci Bonifácio, Andressa Keiko Matsumoto, Chiara Cristina Bortolasci, André de Souza Nogueira, Francis Fregonesi Brinholi, Helena Kaminami Morimoto, Lucio Baena de Melo, Estefânia Gastaldello Moreira and Décio Sabbatini Barbosa.

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Clinically Relevant Drug Interactions with Anti-Alzheimer’s Drugs

Filippo Caraci, Janet Sultana, Filippo Drago and Edoardo Spina.

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Exercise Induced Neuroplasticity to Enhance Therapeutic Outcomes of Cognitive Remediation in Schizophrenia: Analyzing the Role of Brain- Derived Neurotrophic Factor

Carlos Campos, Nuno BF Rocha, Antonio E Nardi, Eduardo Lattari and Sergio Machado.

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GABAA Receptors as Targets for the Management of Pain-Related Disorders: Historical Perspective and Update

Bradford D Fischer.

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Suicide Prevention in Schizophrenia: Do Long-Acting Injectable Antipsychotics (LAIs) have a Role?

Maurizio Pompili, Laura Orsolini, Dorian A. Lamis, David R. Goldsmith, Adele Nardella, Giulia Falcone, Valentina Corigliano, Mario Luciano and Andrea Fiorillo.

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Demonstration of Biological and Immunological Equivalence of a Generic Glatiramer Acetate

Josephine D D`Alessandro, Kevin Garofalo, Ganlin Zhao, Christopher Honan, Jay Duffner, Ishan Capila, Ian Fier, Ganesh Kaundinya, Daniel Kantor and Tanmoy Ganguly.

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The TLR9 Antagonist iCpG-ODN at Different Dosages Inhibits Cerebral Ischemia/Reperfusion Injury in Mice

Ying Zhou, Jingrui Pan, Qingxia Peng, Zhaofei Dong Dong, Lingna Deng Deng and Yidong Wang.

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Alzheimer’s Disease and the Routine Clinical Use of CSF Biomarkers

Alessandro Martorana.

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Inhibition of Butyrylcholinesterase with Fluorobenzylcymserine, An Experimental Alzheimer’s Drug Candidate: Validation of Enzoinformatics Results by Classical and Innovative Enzyme Kinetic Analyses

Mohammad Amjad Kamal, Shazi Shakil, Muhammad S. Nawaz, Qian-sheng Yu, Harold W. Holloway, Y Tan, Xianqin Qu and Nigel H Greig.

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Monoamine Oxidase B Inhibitors in Parkinson's Disease

Livia Dézsi and László Vécsei.

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Increase Signaling of Wnt/β-Catenin Pathway and Presence of Apoptosis in Cerebellum of Kindled Rats

Carmen Rubio-Osornio, Artemio Rosiles-Abonce, Cristina Trejo-Solís, Moisés Rubio-Osornio, Cesar Mendoza, Verónica Custodio, Juan Carlos Martínez-Lazcano, Edith González and Carlos Paz.

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Advanced Structure-Activity Relationships Applied to Mentha spicata L. Subsp. spicata Essential Oil Compounds as AChE and NMDA Ligands, in Comparison with Donepezil, Galantamine and Memantine – New Approach in Brain Disorders Pharmacology

Speranta Avram, Mernea Maria, Eyup Bagci, Lucian Hritcu, Livia-Cristina Borcan and Dan Mihailescu.

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Desmoteplase for Acute Ischemic Stroke: A Systematic Review and Meta-analysis of RCTs

Ahmed Elmaraezy, Abdelrahman Ibrahim Abushouk, Soha Saad, Moutaz Eltoomy, Osama Mahmoud, Hossam Mahmoud Hassan, Ahmed Aboelmakarem, Ahmed Aboel fotoh, Farah Althaher, Nguyen Tien Huy and Kenji Hirayama.

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The Resting-State Functional Connectivity of the Default Mode Networks in Patients With Obstructive Sleep Apnea-Hypopnea Syndrome

Ting Chen, Ming Yang, Bin Liu, Yu-ting Liu, Hui-xin Zhang, Chuan-chuan Liu, Yue Zhu, Zhi-chun Huang and Ti-fei Yuan.

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Subacute Fluoxetine Reduces Signs of Hippocampal Damage Induced by a Single Convulsant Dose of 4-Aminopyridine in Rats

Ahmed Anis Shiha, Rubén Fernández de la Rosa, Mercedes Delgado, Miguel Angel Pozo and Luis García-García.

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Caffeine; the Forgotten Potential for Parkinson's Disease

Ahmed Negida, Mohamed Elfil, Attia Attia, Eslam Farahat, Mohamed Gabr, Ahmed Essam, Hussein Ahmed and Doaa Attia.

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The Positive Synergism of CPT and MK-801 in Behavioral Tests and in Reduction of Environmental Stress and Redox Signaling Changes in Mice Cerebral Cortex

Mariola Herbet, Aleksandra Szopa, Sylwia Wośko, Anna Serefko, Magdalena Izdebska, Monika Gawrońska-Grzywacz, Iwona Piątkowska-Chmiel, Martyna Janas, Renata Gieroba, Agnieszka Korga, Ewa Poleszak and Jarosław Dudka.

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Lithium Restores Age Related Olfactory Impairment in the Ts65Dn Mouse Model of Down Syndrome

Sandra Guidi, Patrizia Bianchi, Fiorenza Stagni, Andrea Giacomini, Marco Emili, Stefania Trazzi, Elisabetta Ciani and Renata Bartesaghi.

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Metabotropic Glutamate Receptor 7 (mGluR7) as a Target for the Modulating Pain-Evoked Activities of Neurons in the Hippocampal CA3 Region of Rats

Xinya Wei, Dongxiao Yang, Tiefeng Shi, Jianing Wang, Yunling Deng, Xuezhu Qiao, Chunxiao Yang and Man-Ying Xu.

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The Protective Effect of Jatrorrhizine against Oxidative Stress in Primary Rat Cortical Neurons

Tao Luo, Xiuyin Shen, Sheng Li, Ting Ouyang and Huaqiao Wang.

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Every Cloud Has a Silver Lining: Proneurogenic Effects of Aβ Oligomers and HMGB-1 via Activation of the RAGE-NF-κB Axis

Valeria Bortolotto and Mariagrazia Grilli.

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