E-Pub Articles Ahead of Print ::: Current Medicinal Chemistry

ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)


Volume 24, 42 Issues, 2017


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Current Medicinal Chemistry

This journal supports open access

Aims & ScopeAbstracted/Indexed in

Ranking and Category:
  • 10th of 59 in Chemistry & Medicinal
  • 63rd of 253 in Pharmacology & Pharmacy
  • 100th of 289 in Biochemistry & Molecular Biology

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Editor-in-Chief:
Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK


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Current: 3.455
5 - Year: 3.792

E-Pub Articles Ahead of Print

MRP1-dependent Collateral Sensitivity of Multidrug-resistant Cancer Cells: Identifying Selective Modulators Inducing Cellular Glutathione Depletion


Doriane Lorendeau, Lauriane Dury, Rachad Nasr, Ahcène Boumendjel, Elisabetta Teodori, Michael Gütschow, Pierre Falson, Attilio Di Pietro and Hélène Baubichon-Cortay.


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Ketogenic Diet and Other Dietary Intervention Strategies in the Treatment of Cancer


Matteo Vergati, Eriseld Krasniqi, Girolamo Del Monte, Silvia Riondino, Doriana Vallone, Fiorella Guadagni, Patrizia Ferroni and Mario Roselli.


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Recent Insights into the Development of Preclinical Trastuzumab- Resistant HER2+ Breast Cancer Models


Paula González-Alonso, Ion Cristóbal, Sandra Zazo, Ester Martín-Aparicio, Cristina Chamizo, Juan Madoz-Gúrpide, Ana Rovira, Pilar Eroles, Ana Lluch, Joan Albanell and Federico Rojo.


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Current Strategies in the Modification of PLGA–based Gene Delivery System


Mohammad Ramezani, Mahboubeh Ebrahimian and Maryam Hashemi.


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Ureas: Applications in Drug Design and Development


Ajit Dhananjay Jagtap, Nagendra Bharatrao Kondekar, Amit A. Sadani and Ji-Wang Chern.


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Trypanothione Reductase and Superoxide Dismutase as Current Drug Targets for Trypanosoma cruzi: An Overview of Compounds with Activity against Chagas Disease


Iván Beltrán-Hortelano, Silvia Pérez-Silanes and Silvia Galiano.


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Vitamin D/VDR, Probiotics, and Gastrointestinal Diseases


Mei Shang and Jun Sun.


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Sex Differences in Alcohol Use Disorder


Roberta Agabio, Claudia Pisanu, Gian Luigi Gessa and Flavia Franconi.


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Vitamin D and the Epigenetic Machinery in Colon Cancer


Meiyan Sun and Bin Guo.


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Eryptosis: Ally or Enemy


Marilena Briglia, Maria Antonia Rossi and Caterina Faggio.


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Novel Antibacterial Compounds and their Drug Targets - Successes and Challenges


Agnieszka A. Kaczor, Andrzej Polski, Karolina Sobótka-Polska, Anna Pachuta-Stec, Magdalena Makarska-Bialokoz and Monika Pitucha.


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Control of Inflammatory Bowel Disease and Colorectal Cancer by Synthetic Vitamin D Receptor Ligands


Ichiro Takada and Makoto Makishima.


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New Insights into Vitamin D and Autophagy in Inflammatory Bowel Diseases


Hyun-Woo Suh, Jin Kyung Kim, Tae Sung Kim and Eun-Kyeong Jo.


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Magnesium in Pain Research: State of the Art


Dragana Srebro, Sonja Vučković, Aleksandar Milovanović, Jovan Košutić, Katarina Savić Vujović and Milica Prostran.


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Comparison of Clinical Outcomes Between Genders Following Antihypertensive Therapy: A Meta-Analysis


Paolo Giorgini, Amirhossein Sahebkar, Valeria Raparelli, Cosimo Andrea Stamerra, Marco Petrarca, Davide Grassi, Claudio Ferri and Paolo Di Giosia.


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Possible Molecular Mechanisms by Which Vitamin D Prevents Inflammatory Bowel Disease and Colitis-Associated Colorectal Cancer


Zijian Luan, Yiming Ma, Yu Xin, Jiaming Qian and Hongying Wang.


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Structure-activity Relationship Studies of New Marine Anticancer Agents and their Synthetic Analogues


Sergey N. Fedorov, Valentin A. Stonik, Friedemann Honecker and Sergey Dyshlovoy.


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Pregnancy-Specific β1-Glycoproteins: Combined Biomarker Roles, Structure/Function Relationships and Implications for Drug Design


Nurbubu T. Moldogazieva, Innokenty M. Mokhosoev and Alexander A Terentiev.


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New Insights Emerging from Recent Investigations on Human Group II Pyridoxal 5’-Phosphate Decarboxylases


Alessandro Paiardini, Giorgio Giardina, Giada Rossignoli, Carla Borri Voltattorni and Mariarita Bertoldi.


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Lipids at the Cross-Road of Autoimmunity in Multiple Sclerosis


Marcella Reale and Silvia Sánchez-Ramón.


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Phytogenic Polyphenols as Glycogen Phosphorylase Inhibitors: The Potential of Triterpenes and Flavonoids for Glycaemic Control in Type 2 Diabetes


George A. Stravodimos, Ben A. Chetter, Efthimios Kyriakis, Anastassia L. Kantsadi, Demetra S.M. Chatzileontiadou, Vassiliki T. Skamnaki, Atsushi Kato, Joseph M. Hayes and Demetres D Leonidas.


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Treatment and Response to Statins: Gender-related Differences


Valeria Raparelli, Gaetano Pannitteri, Tommaso Todisco, Filippo Toriello, Laura Napoleone, Roberto Manfredini and Stefania Basili.


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Scutellarin Attenuates Microglia-Mediated Neuroinflammation and Promotes Astrogliosis in Cerebral Ischemia - A Therapeutic Consideration


Chun-Yun Wu, Ming Fang, Aparna Karthikeyan, Yun Yuan and Eng-Ang Ling.


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Emerging Nanocarriers-Based Approaches to Diagnose and Reduce Vascular Inflammation in Atherosclerosis


Manuela Calin and Ileana Manduteanu.


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Human Serum Albumin as Chiral Selector in Enantioselective High- Performance Liquid Chromatography


Carlo Bertucci and Daniele Tedesco.


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Recent Advances of Graphene-Based Hybrids with Magnetic Nanoparticles for Biomedical Applications


Núria Alegret, Alejandro Criado and Maurizio Prato.


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Oxidative Stress & FoxO Transcription Factors in Cardiovascular Aging


Juewon Kim, Si Young Cho, Donghyun Cho, Su Hwan Kim, Dae Bang Seo and Song Seok Shin.


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Alzheimer's Disease: A Review from the Pathophysiology to Diagnosis, New Perspectives for Pharmacological Treatment


Leide Caroline dos Santos Picanço, Priscilla Farias Ozela, Maiara de Fátima de Brito Brito, Abraão Alves Pinheiro, Elias Carvalho Padilha, Francinaldo Sarges Braga, Carlos Henrique Tomich de Paula da Silva, Cleydson Breno Rodrigues dos Santos, Joaquín María Campos Rosa and Lorane Izabel da Silva Hage-Melim.


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Visual Sexual Stimulation and Erection, a Brief Review with New fMRI Data


Sharon L Wu, Maggie SM Chow, YL Jiang, Jingjin Yang, Hao Zhou and David T Yew.


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Human Host Defense Peptides – Role in Maintaining Human Homeostasis and Pathological Processes


Malgorzata Anna Dawgul, Katarzyna Ewa Greber, Wieslaw Sawicki and Wojciech Kamysz.


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Enantiomeric Resolution of (RS)-Naproxen and Application of (S)- Naproxen in the Direct and Indirect Enantioseparation of Racemic Compounds by Liquid Chromatography: A Review


Sonika Batra and Ravi Bhushan.


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The Molecular Mechanisms and the Role of hnRNP K Protein Post- Translational Modification in DNA Damage Repair


Jing Lu and Feng-Hou Gao.


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Cysteinet Dysregulation in Muscular Dystrophies: A Pathogenic Network Susceptible to Therapy


Marcos Arturo Martínez-Banaclocha.


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Topoisomerase II Inhibitors and Poisons, and the Influence of Cell Cycle Checkpoints


Nicholas D`Arcy and Brian Gabrielli.


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Bacterially Induced Formation of Infectious Urinary Stones: Recent Developments and Future Challenges


Jolanta Prywer and Marcin Olszynski.


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Microwave Assisted Synthesis of Biorelevant Benzazoles


Kapileswar Seth, Priyank Purohit and Asit K Chakraborti.


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Advances in Medicinal Plants with Effects on Anxiety Behavior Associated to Mental and Health Conditions


Valentina Echeverria, Gjumrakch Aliev, Madeline Foitzick, Marco Ávila-Rodriguez and George E Barreto.


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Phytosomes as Biocompatible Carriers of Natural Drugs


Diogo Matias, Patrícia Rijo and Catarina Pinto Reis.


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A Focused Review of Gender Differences in Antithrombotic Therapy


Andrea Salzano, Pablo Demelo-Rodriguez, Alberto Maria Marra and Marco Proietti.


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Snake Venom Peptides and Low Mass Proteins: Molecular Tools and Therapeutic Agents


J.R. Almeida L.M. Resende, R. K. Watanabe, V.C. Corassola, S. Huancahuire-Vega, C. A. da S. Caldeira, A. Coutinho-Neto, A. M. Soares, N. Vale, P. A. de C. Gomes, S. Marangoni, L. de A. Calderon and S L Da Silva.


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Recent Development in the Discovery of Anaplastic Lymphoma Kinase (ALK) Inhibitors for Non-Small Cell Lung Cancer


Jingru Liu and Shutao Ma.


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Bioactive Sutures: A Review of the Advances in Surgical Sutures Functionalization


Feras Alshomer, Arul Madhavan, Omar Pathan and Wenhui Song.


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Polymeric Biomaterial and Lipid Based Nanoparticles for Oral Drug Delivery


Fahima Dilnawaz.


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Daidzein and its Effects on Brain


Touqeer Ahmed, Sana Javed, Ameema Tariq, Barbara Budzyńska, Grazia D`Onofrio, Maria Daglia, Seyed Fazel Nabavi and Seyed Mohammad Nabavi.


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Algae Polysaccharides’ Chemical Characterization and their Role in the Inflammatory Process


Noelia Flórez, María Jesús González-Muñoz, Daniela Ribeiro, Eduarda Fernandes, Herminia Domínguez and Marisa Freitas.


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Recent Developments of Phototherapy Based on Graphene Family Nanomaterials


Baomei Zhang, Yang Wang, Jiyong Liu and Guangxi Zhai.


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Nanocellulose and its Composites for Biomedical Applications


Ahu Gümrah Dumanlı.


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Computational Modelling of Magnetic Nanoparticle Properties and In Vivo Responses


David A Winkler.


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Leveraging Structural Diversity and Allosteric Regulatory Mechanisms of Protein Kinases in the Discovery of Small Molecule Inhibitors


Gennady M Verkhivker.


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Interplay of Immunity and Vitamin D: Interactions and Implications with Current IBD Therapy


Joe Abdo, Vikrant Rai and Devendra Agrawal.


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Plant Pathogenesis-Related Proteins PR-10 and PR-14 as Components of Innate Immunity System and Ubiquitous Allergens


Ekaterina I. Finkina, Daria N. Melnikova, Ivan V. Bogdanov and Tatiana V Ovchinnikova.


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Anti-Cancer Drug Delivery Using Metal Organic Frameworks (MOFs)


Mihad Ibrahim, Rana Sabouni and Ghaleb A Husseini.


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Nanoparticle Based Delivery of Protease Inhibitors to Cancer Cells


Mateja Prunk and Janko Kos.


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Sex Impact on Biomarkers, Pharmacokinetics and Pharmacodynamics


Flavia Franconi and Ilaria Campesi.


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Gender Differences in Cancer-Associated Venous Thromboembolism


Silvia Riondino, Fiorella Guadagni, Vincenzo Formica, Patrizia Ferroni and Mario Roselli.


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Efficacy, Safety and Immunogenicity of Biosimilars in Inflammatory Bowel Diseases: A Systematic Review


Laura Martelli and Laurent Peyrin-Biroulet.


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Cyclic Oligosaccharide Based Chiral Stationary Phases Applicable to Drug Purity Control: A Review


Květa Kalíková, Tereza Šlechtová and Eva Tesařová.


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Coffee: A Dietary Intervention on Type 2 Diabetes?


Susana Casal and Irene Rebelo.


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Medicinal Plants for Diabetes Treatment During Pregnancy


Gustavo Tadeu Volpato, Rafaianne Queiroz Moraes-Souza, Thaigra Sousa Soares, Thais Leal-Silva and Débora Cristina Damasceno.


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Ellagitannins, gallotannins and their metabolites- the contribution to the anti-inflammatory effect of food products and medicinal plants


Anna K. Kiss and Jakub Piwowarski.


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Phytochemical and pharmacological activity profile of Crataegus oxyacantha L. (hawthorn) - A cardiotonic herb


Ilkay Erdogan Orhan.


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Quercetin is a useful medicinal compound showing various actions including control of blood pressure, neurite elongation and epithelial ion transport


Yoshinori Marunaka, Naomi Niisato, Hiroaki Miyazaki, Ken-­Ichi Nakajima, Akiyuki Taruno, Hongxin Sun, Rie Marunaka, Motoki Okui, Toshiro Yamamoto, Narisato Kanamura, Haruka Kogiso, Yukiko Ikeuchi, Makiko Kashio, Shigekuni Hosogi and Takashi Nakahari.


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Cocoa polyphenols: Chemistry, bioavailability and effects on cardiovascular performance


Chiara Fanali, Laura Dugo, Giusy Tripodo and Luca Santi.


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Design and Fabrication of Magnetically Responsive Nanocarriers for Drug Delivery


Slavko Kralj, Tanja Potrč, Petra Kocbek, Silvia Marchesan and Darko Makovec.


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The Antidiabetic Potential of Quercetin: Underlying Mechanisms


Pierre S. Haddad and Hoda M Eid.


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Laboratory-Scale Preparative Enantioseparations of Pharmaceutically Relevant Compounds on Commercially Available Chiral Stationary Phases for HPLC


Roccaldo Sardella, Benedetto Natalini, Federica Ianni, Maura Marinozzi and Antonio Macchiarulo.


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Promising potential of dietary (poly)phenolic compounds in the prevention and treatment of diabetes mellitus


Tânia R. Dias, Marco G. Alves, Susana Casal, Pedro F. Oliveira and Branca M Silva.


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Recent Advances in the Synthesis and Applications of Multimodal Gold-Iron Nanoparticles


Barbara Sanavio and Francesco Stellacci.


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Late-life depression and Alzheimer disease: a potential synergy of the underlying mechanisms


Jerzy Leszek, Elżbieta Trypka, Euphrosyni Koutsourak, Dimitrios Michmizos, Ghulam Md Ashraf and Gjumrakch Aliev.


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Beyond Photodynamic Therapy: Light-Activated Cancer Chemotherapy


Wiktor Szymanski and Friederike Reeßing.


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Expediting the Design, Discovery, and Development of Anticancer Drugs using Computational Approaches


Sun Choi, Stephani Joy Y. Macalino, Minghua Cui and Shaherin Basith.


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The metabolite Trimethylamine‐N‐oxide is an emergent biomarker of human health


Jyoti Chhibber-Goel, Varsha Singhal, Neeraj Parakh, Balram Bhargava and Amit Sharma.


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Vanadium, Ruthenium and Copper compounds: a new class of non-platinum metallodrugs with anticancer activity


Ignacio Esteban León, Juan Fernando Cadavid-Vargas, Ana Laura Di Virgilio and Susana Etcheverry.


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Oncogene Expression Modulation in Cancer Cell Lines by DNA G-Quadruplex-Interactive Small Molecules


Alexandra Paulo and Ana Paula Francisco.


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Cubosomes as Carriers for MRI Contrast Agents


B. Boyd and Nicolas Alcaraz.


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Remote neural stimulation using magnetic nanoparticles


Dino Di Carlo and Andy K Tay.


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Balancing Antioxidant, Hypolipidemic and Anti-inflammatory Activity in a Single Agent: The Example of 2-Hydroxy-2-Substituted Morpholine, 1,4-Benzoxazine and 1,4-Benzothiazine Derivatives as a Potential Therapeutic Approach against Atherosclerosis


Alexios N. Matralis, Eugenia-Ismini Bavavea, Sandra Incerpi, Jens Z. Pedersen and Angeliki P Kourounakis.


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New Therapeutic Property of Dimebon as a Neuroprotective Agent


Aleksey Ustyugov, Elena Shevtsova, George E. Barreto, Ghulam Md. Ashraf, Sergey O. Bachurin and Gjumrakch Aliev.


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Magnetic Materials for the Selective Analysis of Peptide and Protein Biomarkers


Anna Laura Capriotti and Susy Piovesana.


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Chiral Ligand-Exchange Chromatography of Pharmaceutical Compounds on Dinamically Coated (Home-Made) Stationary Phases


Maurizio Remelli.


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Updates on Managing Type 2 Diabetes Mellitus with Natural Products: Towards Antidiabetic Drug Development


Fahmida Alam, Md Asiful Islam, M A Kamal and Siew Hua Gan.


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Microwave-assisted Formation of Organic Disulfides of Biochemical Significance


Debasish Sengupta, Babli Roy and Basudeb Basu.


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Natural AMPK Activators: An Alternative Approach for the Treatment and Management of Metabolic Syndrome


Hitender Sharma and Sunil Kumar.


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Editorial: Mechanisms and Therapeutic Strategies for Major Neurological Disorders: Current Advances and Future Perspectives


Weihai Ying.


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