E-Pub Articles Ahead of Print ::: Current Medicinal Chemistry

ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)

Volume 22, 38 Issues, 2015

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Current Medicinal Chemistry

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  • 6th of 59 in Chemistry & Medicinal
  • 47th of 254 in Pharmacology & Pharmacy
  • 81st of 289 in Biochemistry & Molecular Biology

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Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge

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E-Pub Articles Ahead of Print

Lipoprotein-Related and Apolipoprotein-Mediated Delivery Systems for Drug Targeting and Imaging

Gunter Almer, Harald Mangge, Andreas Zimmer and Ruth Prassl.

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Inhibitors of Angiogenesis in Cancer Therapy – Synthesis and Biological Activity

Monika Gensicka, Agnieszka Głowacka, Krystyna Dzierzbicka and Grzegorz Cholewinski.

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Phytocannabinoids for Cancer Therapeutics: Recent Updates and Future Prospects

Kalpesh R. Patil, Sameer N. Goyal, Charu Sharma, Chandragouda R. Patil and Shreesh Ojha.

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Novel Therapeutic Strategy in the Management of COPD: A Systems Medicine Approach

Filippo Lococo, Alfredo Cesario, Alessandra Del Bufalo, Alessia Ciarrocchi, Giulia Prinzi, Marco Mina, Stefano Bonassi and Patrizia Russo.

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Angiotensin II Type 1 Receptor Binding Molecule ATRAP as a Possible Modulator of Renal Sodium Handling and Blood Pressure in Pathophysiology

K. Tamura, H. Wakui, K. Azushima, K. Uneda, S. Haku, R. Kobayashi, K. Ohki, K. Haruhara, S. Kinguchi, M. Matsuda, A. Yamashita and S Umemura.

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Atherosclerotic and Non-Atherosclerotic Coronary Heart Disease in Women

Genovefa Kolovou, Vana Kolovou, Maria Koutelou M and Sophie Mavrogeni.

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Unfolded Protein Response and PERK Kinase as a New Therapeutic Target in the Pathogenesis of Alzheimer’s Disease

Wioletta Rozpędek, Łukasz Markiewicz, J. Alan Diehl, Dariusz Pytel and Ireneusz Majsterek.

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Exosomes: A Promising Factor Involved in Cancer Hypoxic Microenvironments

Yuehua Yang, Xi Yang, Yan Yang, Hongcheng Zhu, Xiaochen Chen, Hao Zhang, Feng Wang, Qin Qin, Hongyan Cheng and Xinchen Sun.

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Curious (Old and New) Antiviral Nucleoside Analogues with Intriguing Therapeutic Potential

Erik De Clercq.

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Role of Serum and Glucocorticoid-Inducible Kinase (SGK)-1 in Senescence: a Novel Molecular Target against Age-Related Diseases

Davide Lauro, Donatella Pastore, Barbara Capuani, Francesca Pacifici, Raffaele Palmirotta, Pasquale Abete, Mario Roselli, Alfonso Bellia, Massimo Federici, Nicola Di Daniele, Paolo Sbraccia, Fiorella Guadagni, Renato Lauro and David Della-Morte.

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Editorial: Inflammation and Atherosclerosis: The Role of Novel Biomarkers (Part-I)

Gerasimos Siasos, Athanasios G. Papavassiliou and Dimitris Tousoulis.

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Editorial: Metabolic Diseases: Drugs and Mitochondrial Targets

Carlos M. Palmeira and Anabela P Rolo.

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Editorial: Mechanisms and Therapeutic Strategies for Major Neurological Disorders: Current Advances and Future Perspectives

Weihai Ying.

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Tissue-specific Glucocorticoid Signaling May Determine the Resistance Against Glucocorticoids in Autoimmune Diseases

Á. Szappanos, Z. Nagy, B. Kovács, G. Poór, M. Tóth, K. Rácz, E. Kiss and A Patócs.

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Purinergic P2X Receptors: Structural and Functional Features Depicted by X-Ray and Molecular Modelling Studies

Leanne Grimes and Mark T Young.

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Polymers and Formulation Strategies of Nanofibrous Systems for Drug Delivery Application and Tissue Engineering

I. Sebe, B. Kállai-Szabó, R. Zelkó and D Szabó.

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Glucocorticoids in Patients with Rheumatic Diseases: Friends or Enemies of Bone?

Fedra Ciccarelli, Massimo De Martinis and Lia Ginaldi.

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Bioactivation of Drugs: Enzymes, Reactive Metabolites and Adverse Reactions

Hilmi Orhan.

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p38 MAPK: A Potential Target of Chronic Pain

X. Lin, M. Wang, J. Zhang and R Xu.

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Editorial: Emerging biomarkers for drug development in Amyotrophic Lateral Sclerosis

Sebastiano Cavallaro.

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A Glimpse of Matrix Metalloproteinases in Diabetic Nephropathy

X. Xu, L. Xiao, P. Xiao, S. Yang, G. Chen, F. Liu, Y.S. Kanwar and L Sun.

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Disturbed Tryptophan Metabolism in Cardiovascular Disease

H. Mangge, I. Stelzer, E.Z. Reininghaus, D. Weghuber, T.T. Postolache and D Fuchs.

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Editorial: Cardiovascular drug therapy in paediatric age: from metabolomics to clinical practice

Bassareo PP and Fanos V.

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Editorial: Prevention of microbial biofilms - the contribution of micro and nanostructured materials

Alexandru Mihai Grumezescu and Carmen Mariana Chifiriuc.

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EDITORIAL: New Insight into Lipid Disorders

Valentina Pallottini.

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Adipocytes Contribute to Resistance of Human Melanoma Cells to Chemotherapy and Targeted Therapy

M. Chi, J. Chen, Y. Ye, Hsin-Yi Tseng, F. Lai, K.H. Tay, L. Jin, S.T. Guo, C.C. Jiang and XD Zhang.

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P38 MAPK Contributes to Resistance and Invasiveness of HER2- Overexpressing Breast Cancer

S.M. Donnelly, E. Paplomata, B.M. Peake, E. Sanabria, Z. Chen and R Nahta.

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The Functional Logic of Cytosolic 5’-Nucleotidases

Piero L Ipata and Francesco Balestri.

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Biophysical Characterization of Glycodendrimers As Nano-carriers for HIV Peptides

M. Ionov, K. Ciepluch, B.R. Moreno, D. Appelhans, J. Sánchez-Nieves, R. Gómez, F.J. de la Mata, M.A. Muñoz-Fernández and M Bryszewska.

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Human Galectin-3 Selective and High Affinity Inhibitors. Present State and Future Perspectives

R. Téllez-Sanz, L. García-Fuentes and A Vargas-Berenguel.

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Nanoparticles Loaded with Nutlin-3 Display Cytotoxicity Towards p53wildtype JVM-2 But Not Towards p53mutated BJAB Leukemic Cells

R. Voltan, P. Secchiero, B. Ruozi, L. Caruso, F. Forni, M. Palomba, G. Zauli and MA Vandelli.

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MEK Inhibition Increases Lapatinib Sensitivity Via Modulation of FOXM1

S.S. Gayle, R.C. Castellino, M.C. Buss and R Nahta.

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1,2,4-Oxadiazoles Identified by Virtual Screening and their Non-Covalent Inhibition of the Human 20S Proteasome

X. Maréchal, E. Genin, L. Qin, O. Sperandio, M. Montes, N. Basse, N. Richy, M.A. Miteva, M. Reboud-Ravaux, J. Vidal and BO Villoutreix.

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Insulin Secretion and Interleukin-1β Dependent Mechanisms in Human Diabetes Remission After Metabolic Surgery

Chih-Yen Chen, Wei-Jei Lee, A. Asakawa, N. Fujitsuka, Keong Chong, Shu-Chun Chen, Shou-Dong Lee and A Inui.

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Serenoa Repens, Lycopene and Selenium: A Triple Therapeutic Approach to Manage Benign Prostatic Hyperplasia

L. Minutoli, A. Bitto, F. Squadrito, H. Marini, N. Irrera, G. Morgia, A. Passantino and D Altavilla.

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Anti-Inflammatory and Antioxidant Effects of Resveratrol in Healthy Smokers A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Trial

S. Bo, G. Ciccone, A. Castiglione, R. Gambino, F. De Michieli, P. Villois, M. Durazzo, P. Cavallo-Perin and M Cassader.

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Developing FGFR4 Inhibitors As Potential Anti-Cancer Agents Via In Silico Design, Supported by In Vitro and Cell-Based Testing

H.K. Ho, G. Németh, Y.R. Ng, E. Pang, C. Szántai-Kis, L. Zsákai, N. Breza, Z. Greff, Z. Horváth, J. Pató, I. Szabadkai, B. Szokol, F. Baska, L. Orfi, A. Ullrich, G. Kéri and BT Chua.

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Design, SAR, Angiogenic Activities Evaluation and Pro-Angiogenic Mechanism of New Marine Cyclopeptide Analogs

J. Li, X. Lu, Q. Wu, G. Yu, Z. Xu, L. Qiu, Z. Pei, Y. Lin and J Pang.

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Prostate Cancer, miRNAs, Metallothioneins and Resistance to Cytostatic Drugs

V. Pekarik, J. Gumulec, M. Masarik, R. Kizek and V Adam.

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Increased Akt Signaling Resulting from the Loss of Androgen Responsiveness in Prostate Cancer

J. Dulinska-Litewka, J.A. McCubrey and P Laidler.

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Inhaled Muscarinic Acetylcholine Receptor Antagonists for Treatment of COPD

P. Montuschi, F. Macagno, S. Valente and L Fuso.

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State of the Art of the Therapeutic Perspective of Sorafenib Against Hematological Malignancies

G. Zauli, R. Voltan, V. Tisato and P Secchiero.

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Therapeutic Monoclonal Antibodies: Strategies and Challenges for Biosimilars Development

Begoña Calvo and Leyre Zuñiga.

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Physico-Chemical Properties Mediating Reproductive and Developmental Toxicity of Engineered Nanomaterials

Luisa Campagnolo, Micol Massimiani, Andrea Magrini, Antonella Camaioni and Antonio Pietroiusti.

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Alkyl Hydroxybenzoic Acid Derivatives that Inhibit HIV-1 Protease Dimerization

O.A. Flausino Jr., L. Dufau, L.O. Regasini, M.S. Petrônio, D.H.S. Silva, T. Rose, V.S. Bolzani and M Reboud-Ravaux.

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Oxidized-LDL and Paraoxonase-1 As Biomarkers of Coronary Artery Disease in Patients with Sleep-Disordered Breathing

F.S. Hackenhaar, D. Martinez, T.M. Medeiros, C. Klein, P.V.G. Alabarse, M.V. Wainstein, S.C. Gonçalves and MS Benfato.

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pKa, Zinc- and Serum Albumin-Binding of Curcumin and Two Novel Biologically- Active Chemically-Modified Curcumins

Yu Zhang, Lorne M. Golub, Francis Johnson and Arnold Wishnia.

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Design, Synthesis and Biological Activity of New Polyenolic Inhibitors of Matrix Metalloproteinases: A Focus on Chemically-Modified Curcumins

Yu Zhang, Ying Gu, Hsi-Ming Lee, Elena Hambardjieva, Kveta Vrankova, Lorne M. Golub and Francis Johnson.

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Subtype-Selective Dopamine Receptor Radioligands for PET Imaging: Current Status and Recent Developments

A. Banerjee and O Prante.

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Targeting DNA Topoisomerase I with Non-Camptothecin Poisons

G.L. Beretta, V. Zuco, P. Perego and N Zaffaroni.

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