E-Pub Articles Ahead of Print ::: Current Medicinal Chemistry

ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)

Volume 22, 38 Issues, 2015

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Current Medicinal Chemistry

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  • 6th of 59 in Chemistry & Medicinal
  • 47th of 254 in Pharmacology & Pharmacy
  • 81st of 289 in Biochemistry & Molecular Biology

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Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge

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E-Pub Articles Ahead of Print

Editorial: Metabolic Diseases: Drugs and Mitochondrial Targets
Carlos M. Palmeira and Anabela P. Rolo
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Insights into the Mechanisms Involved in the Expression and Regulation of Extracellular Matrix Proteins in Diabetic Nephropathy
Chun Hu, Lin Sun, Yachun Han, Xiao Fu, Xiaofen Xiong, Xiaoxuan Xu, Yinghong Liu, Shikun Yang, Fuyou Liu and Yashpal S Kanwar
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Kynurenine Aminotransferases and the Prospects of Inhibitors for the Treatment of Schizophrenia
Gayan S. Jayawickrama, Richard R. Sadig, Guanchen Sun, Alireza Nematollahi, Naveed A. Nadvi, Jane R. Hanrahan, Mark D. Gorrell and W. Bret Church
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Inflammatory Biomarkers and Therapeutic Targets in Heart Failure
Lampros Papadimitriou and Andreas P. Kalogeropoulos
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Circulating Biomarkers Determining Inflammation in Atherosclerosis Progression
Gerasimos Siasos, Vicky Tsigkou, Evangelos Oikonomou, Marina Zaromitidou, Sotiris Tsalamandris, Konstantinos Mourouzis, Manolis Vavuranakis, Anastasiou Maria, Maria Limberi, Vasiliki Gennimata, John N. Boletis, Athanasios G. Papavassiliou and Dimitris Tousoulis
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Editorial: Mechanisms and Therapeutic Strategies for Major Neurological Disorders: Current Advances and Future Perspectives
Weihai Ying
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Tissue-specific Glucocorticoid Signaling May Determine the Resistance Against Glucocorticoids in Autoimmune Diseases
Á. Szappanos, Z. Nagy, B. Kovács, G. Poór, M. Tóth, K. Rácz, E. Kiss and A. Patócs
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Purinergic P2X Receptors: Structural and Functional Features Depicted by X-Ray and Molecular Modelling Studies
Leanne Grimes and Mark T Young
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Polymers and Formulation Strategies of Nanofibrous Systems for Drug Delivery Application and Tissue Engineering
I. Sebe, B. Kállai-Szabó, R. Zelkó and D. Szabó
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Glucocorticoids in Patients with Rheumatic Diseases: Friends or Enemies of Bone?
Fedra Ciccarelli, Massimo De Martinis and Lia Ginaldi
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Bioactivation of Drugs: Enzymes, Reactive Metabolites and Adverse Reactions
Hilmi Orhan
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p38 MAPK: A Potential Target of Chronic Pain
X. Lin, M. Wang, J. Zhang and R. Xu
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Editorial: Emerging biomarkers for drug development in Amyotrophic Lateral Sclerosis
Sebastiano Cavallaro
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A Glimpse of Matrix Metalloproteinases in Diabetic Nephropathy
X. Xu, L. Xiao, P. Xiao, S. Yang, G. Chen, F. Liu, Y.S. Kanwar and L. Sun
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Disturbed Tryptophan Metabolism in Cardiovascular Disease
H. Mangge, I. Stelzer, E.Z. Reininghaus, D. Weghuber, T.T. Postolache and D. Fuchs
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Editorial: Cardiovascular drug therapy in paediatric age: from metabolomics to clinical practice
Bassareo PP and Fanos V
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Editorial: Prevention of microbial biofilms - the contribution of micro and nanostructured materials
Alexandru Mihai Grumezescu and Carmen Mariana Chifiriuc
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EDITORIAL: New Insight into Lipid Disorders
Valentina Pallottini
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Adipocytes Contribute to Resistance of Human Melanoma Cells to Chemotherapy and Targeted Therapy
M. Chi, J. Chen, Y. Ye, Hsin-Yi Tseng, F. Lai, K.H. Tay, L. Jin, S.T. Guo, C.C. Jiang and X.D. Zhang
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P38 MAPK Contributes to Resistance and Invasiveness of HER2- Overexpressing Breast Cancer
S.M. Donnelly, E. Paplomata, B.M. Peake, E. Sanabria, Z. Chen and R. Nahta
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The Functional Logic of Cytosolic 5’-Nucleotidases
Piero L Ipata and Francesco Balestri
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Biophysical Characterization of Glycodendrimers As Nano-carriers for HIV Peptides
M. Ionov, K. Ciepluch, B.R. Moreno, D. Appelhans, J. Sánchez-Nieves, R. Gómez, F.J. de la Mata, M.A. Muñoz-Fernández and M. Bryszewska
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Human Galectin-3 Selective and High Affinity Inhibitors. Present State and Future Perspectives
R. Téllez-Sanz, L. García-Fuentes and A. Vargas-Berenguel
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Nanoparticles Loaded with Nutlin-3 Display Cytotoxicity Towards p53wildtype JVM-2 But Not Towards p53mutated BJAB Leukemic Cells
R. Voltan, P. Secchiero, B. Ruozi, L. Caruso, F. Forni, M. Palomba, G. Zauli and M.A. Vandelli
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MEK Inhibition Increases Lapatinib Sensitivity Via Modulation of FOXM1
S.S. Gayle, R.C. Castellino, M.C. Buss and R. Nahta
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1,2,4-Oxadiazoles Identified by Virtual Screening and their Non-Covalent Inhibition of the Human 20S Proteasome
X. Maréchal, E. Genin, L. Qin, O. Sperandio, M. Montes, N. Basse, N. Richy, M.A. Miteva, M. Reboud-Ravaux, J. Vidal and B.O. Villoutreix
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Insulin Secretion and Interleukin-1β Dependent Mechanisms in Human Diabetes Remission After Metabolic Surgery
Chih-Yen Chen, Wei-Jei Lee, A. Asakawa, N. Fujitsuka, Keong Chong, Shu-Chun Chen, Shou-Dong Lee and A. Inui
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Serenoa Repens, Lycopene and Selenium: A Triple Therapeutic Approach to Manage Benign Prostatic Hyperplasia
L. Minutoli, A. Bitto, F. Squadrito, H. Marini, N. Irrera, G. Morgia, A. Passantino and D. Altavilla
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Anti-Inflammatory and Antioxidant Effects of Resveratrol in Healthy Smokers A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Trial
S. Bo, G. Ciccone, A. Castiglione, R. Gambino, F. De Michieli, P. Villois, M. Durazzo, P. Cavallo-Perin and M. Cassader
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Developing FGFR4 Inhibitors As Potential Anti-Cancer Agents Via In Silico Design, Supported by In Vitro and Cell-Based Testing
H.K. Ho, G. Németh, Y.R. Ng, E. Pang, C. Szántai-Kis, L. Zsákai, N. Breza, Z. Greff, Z. Horváth, J. Pató, I. Szabadkai, B. Szokol, F. Baska, L. Orfi, A. Ullrich, G. Kéri and B.T. Chua
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Design, SAR, Angiogenic Activities Evaluation and Pro-Angiogenic Mechanism of New Marine Cyclopeptide Analogs
J. Li, X. Lu, Q. Wu, G. Yu, Z. Xu, L. Qiu, Z. Pei, Y. Lin and J. Pang
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Prostate Cancer, miRNAs, Metallothioneins and Resistance to Cytostatic Drugs
V. Pekarik, J. Gumulec, M. Masarik, R. Kizek and V. Adam
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Increased Akt Signaling Resulting from the Loss of Androgen Responsiveness in Prostate Cancer
J. Dulinska-Litewka, J.A. McCubrey and P. Laidler
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Inhaled Muscarinic Acetylcholine Receptor Antagonists for Treatment of COPD
P. Montuschi, F. Macagno, S. Valente and L. Fuso
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State of the Art of the Therapeutic Perspective of Sorafenib Against Hematological Malignancies
G. Zauli, R. Voltan, V. Tisato and P. Secchiero
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Therapeutic Monoclonal Antibodies: Strategies and Challenges for Biosimilars Development
Begoña Calvo and Leyre Zuñiga
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Physico-Chemical Properties Mediating Reproductive and Developmental Toxicity of Engineered Nanomaterials
Luisa Campagnolo, Micol Massimiani, Andrea Magrini, Antonella Camaioni and Antonio Pietroiusti
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Alkyl Hydroxybenzoic Acid Derivatives that Inhibit HIV-1 Protease Dimerization
O.A. Flausino Jr., L. Dufau, L.O. Regasini, M.S. Petrônio, D.H.S. Silva, T. Rose, V.S. Bolzani and M. Reboud-Ravaux
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Oxidized-LDL and Paraoxonase-1 As Biomarkers of Coronary Artery Disease in Patients with Sleep-Disordered Breathing
F.S. Hackenhaar, D. Martinez, T.M. Medeiros, C. Klein, P.V.G. Alabarse, M.V. Wainstein, S.C. Gonçalves and M.S. Benfato
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pKa, Zinc- and Serum Albumin-Binding of Curcumin and Two Novel Biologically- Active Chemically-Modified Curcumins
Yu Zhang, Lorne M. Golub, Francis Johnson and Arnold Wishnia
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Design, Synthesis and Biological Activity of New Polyenolic Inhibitors of Matrix Metalloproteinases: A Focus on Chemically-Modified Curcumins
Yu Zhang, Ying Gu, Hsi-Ming Lee, Elena Hambardjieva, Kveta Vrankova, Lorne M. Golub and Francis Johnson
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Subtype-Selective Dopamine Receptor Radioligands for PET Imaging: Current Status and Recent Developments
A. Banerjee and O. Prante
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Targeting DNA Topoisomerase I with Non-Camptothecin Poisons
G.L. Beretta, V. Zuco, P. Perego and N. Zaffaroni
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