E-Pub Articles Ahead of Print ::: Anti-Cancer Agents in Medicinal Chemistry

ISSN: 1875-5992 (Online)
ISSN: 1871-5206 (Print)


Volume 16, 12 Issues, 2016


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Anti-Cancer Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Cancer Agents

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  • 27th of 59 in Chemistry, Medicinal

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Editor-in-Chief:
Michelle Prudhomme
Universite Blaise Pascal - C.N.R.S
Aubiere Cedex
France


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E-Pub Articles Ahead of Print

O-6-methylguanine-DNA Methyltransferase Inhibits Gastric Carcinoma Cell Migration and Invasion by Downregulation of Matrix Metalloproteinase 2


Chenglong Li, Li Deng, Qiaoming Zhi, Qingyou Meng, Aimin Qian, Hongfei Sang, Jiazeng Xia and Xiaoqiang Li.


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1, 3, 6-Trihydroxy-7-methyl-9, 10-anthracenedione isolated from genus Lindera with anti-cancer activity


Guoqing Wei, Hui Chen, Fangyuan Nie, Xiaofeng Ma and Hezhong Jiang.


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Effect of PUFAs oral administration on the amount of Apoptotic Caspases Enzymes in gastric cancer patients undergoing chemotherapy


Homayun Dolatkhah, Ahmad Movahedian, Mohammad-Hossein Somi, Mahmud Aghaei, Naser Samadi, Ahmad Mirza-Aghazade and Ali Esfahani.


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Inhibitors of Cancer Stem Cells


María E. García-Rubiño, César Lozano-López and Joaquín M Campos.


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Long noncoding RNA C21orF96 promotes the migration, invasion and lymph node metastasis in gastric cancer


Ziguo Yang, Qiaoming Zhi, Dan Wang, Li Zhang, Yuting Kuang, Ruizhen Miao, Yulong Shi and Xiaobo Guo.


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Nano-Hydroxyapatite Doped with Ho-166 as Drug Delivery System for Bone Cancer Therapy


Franciana Maria Rosa da Silva, Julio Cezar de Almeida Junior, Elizabeth Eugênio de Mello Oliveira, Marta de Souza Albernaz, Alexandre Malta Rossi and Ralph Santos-Oliveira.


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Hepato and Cardiotoxicity of Chemotherapeutic Treatment Evaluated by Means of Small Animal Imaging.


Fiorella Carla Tesán, Mariano Portillo, Diego Martinel-Lamas, Vanina Araceli Medina, María Jimena Salgueiro and Marcela Zubillaga.


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Perspectives of Benzimidazole Derivatives as Anticancer Agents in the New Era


Snehlata Yadav, Balasubramanian Narasimhan and Harmeet kaur.


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Biological Potential of Halfsandwich Ruthenium(II) and Iridium(III) Complexes


Gerd Ludwig, Marija Mojić, Mirna Z. Bulatović, Sanja Mijatović, Danijela Maksimović-Ivanić, Dirk Steinborn and Goran N Kaluđerović.


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15,16-dihydrotanshinone I induces apoptosis and inhibits the proliferation, migration of human osteosarcoma cell line 143B in vitro


Xuepeng Chen, Qihong Li, Yan He, Hongjiang Du, Zhajun Zhan, Hong zhao, Jiejun Shi, Qingsong Ye and Ji'an Hu.


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Flavonoids with Therapeutic Potential in Prostate Cancer


Bao Vue, Sheng Zhang and Qiao-Hong Chen.


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Research Progress on the Antitumor Effects of Rhein: Literature Review


Chao Wu, Hongyan Cao, Hua Zhou, Lin Sun, Jingui Xue, Jianyuan Li, Yanqin Bian, Runfei Sun, Shu Dong, Ping Liu and Mingyu Sun.


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Synthesis of Diflunisal thiazolidinones as anticancer agents


Sevil Şenkardeş, Özlem Bingöl Özakpınar, Derya Özsavcı, Azize Şener, Özge Çevik and ŞGüniz Küçükgüzel.


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Up-regulated circulating miR-106a by DNA methylation promised a potential diagnostic and prognostic marker for gastric cancer


Renshun Yuan, Gang Wang, Qiaoming Zhi, Huabin Chen, Ye Han, Bin Wang, Zhongyang Kou, Hao Hu, Zhaoji Guo, Xiaofeng Xue and Hong Zhao.


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Lgr5 contributes to intestinal metaplasia during gastric carcinogenesis: a meta-analysis


Ye Han, Hugang Shen, Xiaofeng Xue, Bin Yuan, Yuting Kuang, Qiaoming Zhi and Hong Zhao.


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Statins and Alkylphospholipids as New Anticancer Agents Targeting Lipid Metabolism


Sonia Apostolova, Reneta Toshkova, Albena Momchilova and Rumiana Tzoneva.


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Glycodendrimer PPI as a Potential Drug in Chronic Lymphocytic Leukemia. The Influence of Glycodendrimer on Apoptosis in in vitro B-CLL Cells Defined by Microarrays


Ida Franiak-Pietryga, Ewelina Ziółkowska, Barbara Ziemba, Dietmar Appelhans, Brigitte Voit, Aleksandra Kaczmarek, Tadeusz Robak, Barbara Klajnert-Maculewicz, Barbara Cebula-Obrzut, Piotr Smolewski, Maciej Borowiec and Maria Bryszewska.


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Synthesis, in vitro antiproliferative and antiinflammatory activities, and kinase inhibitory effects of a new series of 1,3,4-triarylpyrazole derivatives


Mohammed El-Gamal.


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Design, synthesis and evaluation of 5-pyridin-4-yl-2-thioxo-[1,3,4]oxadiazol-3-yl derivatives as anti-angiogenic agents Targeting VEGFR-2.


Umesh Bhanushali, Samidha Kalekar-Joshi, Renuka Kulkarni-Munshi, Swapna Yellanki, Raghavender Medishetty, Pushkar Kulkarni and C S Ramaa.


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Synthesis and in vitro evaluation of the anticancer potential of new aminoalkanol derivatives of xanthone


Natalia Szkaradek, Daniel Sypniewski, Anna M. Waszkielewicz, Agnieszka Gunia-Krzyżak, Anna Galilejczyk, Sabina Gałka, Henryk Marona and Ilona Bednarek.


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Synthesis and Anticancer Study of novel 4H-Chromen Derivatives


Xiaolin Lu, Gaochao Dong, Ying Zheng, Chao Zhang, Yang Qiu, Tao Lu and Xiang Zhou.


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Effects of Epirubicin and Cisplatin against 4T1 Breast Cancer Cells are Enhanced by Myrtucommulone-A


Kenan izgi, Banu iskender, Cagri Sakalar, Aslıhan Arslanhan, Esra Hilal Yüksek, Esra Hizar and Halit Canatan.


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Differential Cytotoxicity, Cellular Uptake, Apoptosis and Inhibition of BRCA1 Expression of BRCA1-Defective and Sporadic Breast Cancer Cells Induced by an Anticancer Ruthenium(II)-Arene Compound, RAPTA-EA1


Adisorn Ratanaphan, Tidarat Nhukeaw, Khwanjira Hongthong and Paul J Dyson.


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To Analyze the Amelioration of Phenobarbital Induced Oxidative Stress by Erucin, as Indicated by Biochemical and Histological Alterations


Rohit Arora, Sakshi Bhushan, Rakesh Kumar, Rahul Mannan, Pardeep Kaur, Bikram Singh, Ritika Sharma, Adarsh Pal Vig, Balbir Singh, Amrit Pal Singh and Saroj Arora.


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Epigenetic and miRNAs dysregulation in prostate cancer: the role of nutraceuticals


Alessandra Bosutti, Fabrizio Zanconati, Gabriele Grassi, Barbara Dapas, Sabina Passamonti and Bruna Scaggiante.


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Novel 2-Thienyl- and 2-Benzothienyl-Substituted 6-(2-Imidazolinyl)Benzothiazoles: Synthesis; in vitro Evaluation of Antitumor Effects and Assessment of Mitochondrial Toxicity


Livio Racané, Mirela Sedić, Nataša Ilić, Maja Aleksić, Sandra Kraljević Pavelić and Grace Karminski-Zamola.


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Epidrugs in the Immunotherapy of Cutaneous and Uveal Melanoma


Mario Venza, Maria Visalli, Teresa Catalano, Concetta Beninati, Diana Teti and Isabella Venza.


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Brain-metastatic Breast Cancer: Clinical Considerations and Pharmacological Approaches


Ana Carolina Andrade, Daniel Sartori Ferruzzi and Carolina Panis.


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Circulating tumor cells: a new window for diagnosis and evaluation of cancer


Meihui Liu, Min Tang, Ming Li, Feng Gao, Can Shi, Jing Hou and Wenbin Zeng.


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Rapamycin-loaded immunoliposomes functionalized with trastuzumab: a strategy to enhance cytotoxicity to HER2-positive breast cancer cells


Josimar O. Eloy, Raquel Petrilli, Robert W. Brueggemeier, Juliana Maldonado Marchetti and Robert J Lee.


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8-bromo-7-methoxychrysin reversed M2 polarization of tumor-associated macrophages induced by liver cancer stem-like cells


Shuwen Sun, Yinghong Cui, Kaiqun Ren, Meifang Quan, Zhenwei Song, Hui Zou, Duo Li, Yu Zheng and Jianguo Cao.


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4-Anilinoquinazoline Derivatives with Epidermal Growth Factor Receptor Inhibitor Activity


Fang Liu, Yinjiu Huang, Hao Liu, Leina Li, Gang Liu, Yun Cheng, Yan Xu and Wenwen Chen.


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Exploring the binding affinity of novel syringic acid analogues and critical determinants of selectivity as potent proteasome inhibitors


Srinivasulu Cheemanapalli, CM Anuradha, P Madhusudhana, M Mahesh, Pongali B Raghavendra and Chitta Suresh Kumar.


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Cordycepin Affects Multiple Apoptotic Pathways to Mediate Hepatocellular Carcinoma Cell Death


Yulin Zhou, Zhihua Guo, Qingfan Meng, Jiahui Lu, Ning Wang, Hui Liu, Qiming Liang, Yutong Quan, Di Wang and Jing Xie.


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Melatonin Regulates Angiogenic and Inflammatory Proteins in MDA-MB-231 Cell Line and in Co-culture with Cancer-associated Fibroblasts


Larissa Bazela Maschio-Signorini, Gabriela Bottaro Gelaleti, Marina Gobbe Moschetta, Thaiz Ferraz Borin, Bruna Victorasso Jardim-Perassi, Juliana Ramos Lopes, Jéssica Zani Lacerda, Rosimeire Aparecida Roela, Newton Antonio Bordin Júnior, Lizandra Akina Corrêa, Jessica Picinin Cardoso and Debora Aparecida Pires de Campos Zuccari.


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Evolving Role of Radiopharmaceuticals in Hepatocellular Carcinoma Treatment


Lu Wu, Feng Shen, Yong Xia and Ye-Fa Yang.


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Fab(nimotuzumab)-HYNIC-99mTc: Antibody Fragmentation for Molecular Imaging Agents


Victoria Calzada, María Fernanda García, Luis Michel Alonso-Martínez, Ximena Camacho, Enzo Goicochea, Marcelo Fernández, Abmel Xiques Castillo, Arlhee Díaz-Miqueli, Normando Iznaga-Escobar, René Leyva Montaña, Omar Alonso, Juan Pablo Gambini and Pablo Cabral.


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The utility of chemotherapy in the treatment of metastatic prostate cancer


Kanika Gupta, Jacob Elkon, Ehab El-Bahesh and Jeanny B Aragon-Ching.


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Regulatory Approaches to Non-clinical Reproductive Toxicity Testing of Anti-Cancer Drugs.


Georg Schmitt and Paul Barrow.


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Sodium Selenite as an Anti-Cancer Agent


Boguslaw Lipinski.


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Preparation and Evaluation of in vitro Self-assembling HSA Nanoparticles for Cabazitaxel


Na Qu, Yating Sun, Jing Xie and Lesheng Teng.


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Thiazolidinone constraint combretastatin analogs as novel antitubulin agents: Design, synthesis, biological evaluation and docking studies


Sahil Sharma, Manish Kumar Gupta, Ajit Kumar Saxena and Preet Mohinder Singh Bedi.


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Autophagy Inhibits Apoptosis Induced by agrocybe aegerita Lectin in Hepatocellular Carcinoma


Wei Liu, Guojun Yu, Wenhui Yu, Xiangdong Ye, Yanxia Jin, Alok Shrestha, Qing Yang and Hui Sun.


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Oleic Acid Protects Against Oxidative Stress Exacerbated by Cytarabine and Doxorubicin in Rat Brain


David Calderón Guzmán, Norma Osnaya Brizuela, Maribel Ortíz Herrera, Hugo Juárez Olguín, Ernestina Hernández García, Armando Valenzuela Peraza and Gerardo Barragán Mejía.


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Fe3O4 Nanoparticles Mediated Synthesis of Novel Isatin-Pyrimidinone Hybrid Molecules as Antioxidant and Cytotoxic Agents


Srinubabu Maddela, Ajitha Makula and N Jayarambabu.


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Disulfiram’s Anticancer Activity: Evidences and Mechanisms


Yang Jiao, Bethany N Hannafon and Wei-Qun Ding.


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The cytotoxic effect of GW843682X on nasopharyngeal carcinoma


Qinyong Hu, Yuxin Chu, Weiguo Hu, Min Peng and Qibin Song.


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New Approaches to Photodynamic Therapy from Type I, II and III to Type IV Using One or More Photons


Kathrin M. Scherer, Roger H. Bisby, Stanley W. Botchway and Anthony W Parker.


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Synthesis of Icaritin and β-anhydroicaritin Mannich Base Derivatives and Their Cytotoxic Activities on Three Human Cancer Cell Lines


Van-Son Nguyen, Ling Shi, Sheng-Chun Wang and Qiu-An Wang.


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In Vitro Anticancer effects of Two New Potent Hydrazide Compounds on Leukemic Cells


Shahrzad Tavakolfar, Elham Musavi, Ali Almasirad, Amir Amanzadeh, Seyyed Mohamamd Atyabi, Parichehr Yaghamii, Somayeh Samiee-Sadr and Mona Salimi.


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In Vivo Inhibition of Proteasome Activity and Tumour Growth by Murraya koenigii Leaf Extract in Breast Cancer Xenografts and by Its Active Flavonoids in Breast Cancer Cells


Bindu Noolu, Ramesh Gogulothu, Mehrajuddin Bhat, Syed SYH Qadri, V Sudhakar Reddy, G Bhanuprakash Reddy and Ayesha Ismail.


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Heterocyclic Drug-polymer Conjugates for Cancer Targeted Drug Delivery


Harmeet Kaur, Sapna D. Desai, Virender Kumar, Pooja Rathi and Jasbir Singh.


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Selective Toxicity of Apigenin on Cancerous Hepatocytes by Directly Targeting their Mitochondria


Enayatollah Seydi, Hamid Reza Rasekh, Ahmad Salimi, Zhaleh Mohsenifar and Jalal Pourahmad.


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Plant Derived Inhibitor Sulforaphane in Combinatorial Therapy Against Therapeutically Challenging Pancreatic Cancer


Shabir Ahmad Ganai, Romana Rashid, Ehsaan Abdullah and Mohammad Altaf.


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Investigation of Fucoidan–Oleic Acid Conjugate for Delivery of Curcumin and Paclitaxel


Uyen Thao Phan, Khanh Tu Nguyen, Toi Van Vo, Wei Duan, Phuong Ha-Lien Tran and Thao Truong-Dinh Tran.


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Clinical Significance of miR-1826 as a Novel Prognostic Biomarker in Colorectal Cancer


You Hu, Bin Yi, Songbing He, Pengfei Liu, Lei Wang, Jing Yu, Daiwei Wan, Jin Zhou, Xinguo Zhu and Qiaoming Zhi.


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Cetuximab immunoliposomes enhances delivery of 5-FU to skin squamous carcinoma cells


Raquel Petrilli, Josimar O. Eloy, Renata F. V. Lopez and Robert J Lee.


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Radiopharmaceuticals in Tumor Hypoxia Imaging: A Review Focused on Medicinal Chemistry Aspects


Pablo Cabral and Hugo Cerecetto.


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Fibroblast Growth Factor Receptor (FGFR): A new target for non-small cell lung cancer therapy


Federica Biello, Giovanni Burrafato, Erika Rijavec, Carlo Genova, Giulia Barletta, Anna Truini, Simona Coco, Maria Giovanna Dal Bello, Angela Alama, Francesco Boccardo and Francesco Grossi.


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Histamine and Histaminergic Receptors in Colorectal Cancer: From Basic Science to Evidence-based Medicine


Giuseppe Losurdo, Mariabeatrice Principi, Bruna Girardi, Maria Pricci, Michele Barone, Enzo Ierardi and Alfredo Di Leo.


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The Role of Tumor Associated Macrophages in the Tumor Microenvironment: Mechanism and Functions


Jie Zhu, Binhua P. Zhou, Min Tao, Jingyi Liu and Wei Li.


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The Role of Stromal Components in Pancreatic Cancer Progression


Mengdan Xu, Qiaoming Zhi, Binhua P. Zhou, Min Tao, Jingyi Liu and Wei Li.


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Breast Cancer: Current Molecular Therapeutic Targets and New Players


Siddavaram Nagini.


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Macromolecular Drug Targets in Cancer Treatment and Thiosemicarbazides as Anticancer Agents


Ş. Güniz Küçükgüzela and Göknil Pelin Coşkuna.


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Docking Studies of Glutamine Valproic Acid Derivative (S)-5-amino-2-(heptan-4- ylamino)-5-oxopentanoic Acid (Gln-VPA) on HDAC8 with Biological Evaluation in HeLa Cells


F Martínez-Ramos, GR Luna-Palencia, I Vásquez-Moctezuma, D Méndez-Luna, MJ Fragoso-Vázquez, J Trujillo-Ferrara, MA Meraz-Ríos, JE Mendieta-Wejebe and J Correa-Basurto.


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Juglone Exerts Cytotoxic, Anti-proliferative and Anti-invasive Effects on Glioblastoma Multiforme in a Cell Culture Model


Dziugas Meskelevicius, Kastytis Sidlauskas, Ruta Bagdonaviciute, Julius Liobikas and Daiva Majiene.


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Role of Carboxypeptidase N Invasion and Migration in Breast Cancer


Ranliang Cui, Peng Zhang and Yueguo Li.


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Design and Synthesis of Some Novel Estrogen Receptor Modulators as Anti-Breast Cancer Agents: In vitro & In vivo Screening, Docking Analysis


Pritam N. Dube and Santosh N Mokale.


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L-Canavanine Potentiates Cytotoxicity of Chemotherapeutic Drugs in Human Breast Cancer Cells


Agustina D. R. Nurcahyanti and Michael Wink.


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New 2-Imino-2H-Chromene-3(N-aryl)carboxamides as Potential Cytotoxic Agents


Rupinder Kaur Gill, Jyoti Kumari and Jitender Bariwal.


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Omega-3 Polyunsaturated Fatty Acids Enhance Cisplatin Efficacy in Gastric Cancer Cells by Inducing Apoptosis via ADORA1


Hong Sheng, Xuehua Chen, Binya Liu, Pu Li and Weixin Cao.


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Targeting the Folate Receptor: Effects of Conjugating Folic Acid to DOX Loaded Polymeric Micelles


Mohamed A. Elkhodiry, Ghaleb A Husseini and Diana Velluto.


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Recent Advances in Heterocyclic Tubulin Inhibitors Targeting the Colchicine Binding Site


Xiaoxin Wu, Qinghui Wang and Wei Li.


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Radiolabeled Nanoparticles for Cancer Diagnosis and Therapy


Jacek Koziorowski, Adina E. Stanciu, Vanessa Gómez-Vallejo and Jordi Llop.


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Lenalidomide in an in vitro Dendritic Cell Model for Malignant Gliomas


Caspar D. Kühnöl, Martin S. Staege and Christof M Kramm.


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Ethanolic Extract of Algerian Propolis and Galangin Decreased Murine Melanoma Tumour Progression


L Benguedouar, M Lahouel, S. C. Gangloff, A Durlach, F Grange, P Bernard and F Antonicelli.


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Synthesis of Arylamino-1,3,5-triazines Functionalized with Alkylating 2-chloroethylamine Fragments and Studies of their Cytotoxicity on the Breast Cancer MCF-7 Cell Line


Justyna Fraczyk, Beata Kolesinska, Monika Swiontek, Wojciech Lipinski, Danuta Drozdowska and Zbigniew Jerzy Kaminski.


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Effects of Anticancer Drugs in Reproductive Parameters of Juvenile Male Animals and Role of Protective Agents


Juliana Elaine Perobelli.


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Design and Synthesis of Coumarin Derivatives as Novel PI3K Inhibitors


Ma Chen-Chen and Zhao-Peng Liu.


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