Editorial Board ::: Reviews on Recent Clinical Trials

ISSN: 1876-1038 (Online)
ISSN: 1574-8871 (Print)


Volume 12, 4 Issues, 2017


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Reviews on Recent Clinical Trials

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Editor-in-Chief:
Ludovico Abenavoli
University Magna Graecia
Catanzaro
Italy


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Editorial Board

Editor-in-Chief:

Ludovico Abenavoli (Biography
Ludovico Abenavoli

Ludovico Abenavoli is associate professor of gastroenterology at the Department of Health Sciences, University “Magna Græcia”, Catanzaro (Italy). Since 2012 he is invited professor at the University of Batna (Algeria), since 2015 he is inviting professor at the University of Novi Sad (Serbia), and since 2016 he is associate professor at the Faculty of Medicine, University “Iuliu Hatieganu” of Cluj-Napoca (Romania). Between 2012 and 2015, he was board member of University Gastroenterology Education Committee (UNIGASTRO), and between 2013 and 2017, he was board member of Italian Society of Gastroenterology and Digestive Endoscopy (S.I.G.E.). Ludovico Abenavoli is author of 144 publications in peer-reviewed international Journals in the field of gastroenterology and hepatology. His main contributions include: the treatment of alcoholic and nonalcoholic liver diseases, the evaluation of health effects of Mediterranean diet, the epidemiology of liver diseases.

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University Magna Graecia
Catanzaro
Italy



Associate Editors:

G. Borgia
University of Naples Federico II
Naples
Italy

S.A. Doggrell
Queensland University of Technology
Queensland
Australia

F. Caponigro
National Tumor Institute of Naples
Naples
Italy

J. Maurel (Biography
J. Maurel

Dr. Joan Maurel, MD PhD, is a consultant medical oncologist in the Department of Medical Oncology, Hospital Clínic, University of Barcelona. Graduating from the Medical school, University Autonoma of Barcelona, he obtained his medical degree in 1989 and the title of specialist in medical Oncology in 1995. His doctoral thesis was read in 1998. Since 2000 he has been working at the Hospital Clinic of Barcelona, as a staff member in the Oncology Department. Dr. Maurel has written more than 100 journal articles with an overall impact factor of 505.4. He is the former President of Grupo Español Multidisciplinar en Cáncer Digestivo (GEMCAD) Cooperative Group and a member of Spanish Society of Medical Oncology (SEOM) and American Society of Clinical Oncology (ASCO).

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University of Barcelona Medical School
Barcelona
Spain

C. Ding (Biography
C. Ding

Dr Changhai Ding is a Professor at University of Tasmanian, Associate Director (International) of Menzies Institute for Medical Research, an Honorary Professor at the University of Sydney, and an Adjunct Professor at Monash University. He is currently a Professor at Southern Medical University, an Adjunct Professor and Director of Arthritis Research Institute at Anhui Medical University and a Guest Professor at Xi’an Jiaotong University and Shanghai University of TCM, China.

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University of Tasmania
Tasmania
Australia

E. Nutescu
University of Illinois
Chicago, IL
USA


Regional Editors:

Region: Asia
K. Akakura (Biography
K. Akakura

Dr. Akakura graduated from School of Medicine, Chiba University, Japan (M.D.), and obtained Ph.D. from Chiba University. Dr. Akakura completed Clinical Resident at Department of Urology, Chiba University Hospital and National Kohnodai Hospital, Japan, and spent 2.5 years as a Post-doctoral Fellow at Department of Cancer Endocrinology, British Columbia Cancer Agency, Canada. Currently He is a Vice President of Japan Community Health-care Organization Tokyo Shinjuku Medical Center. He has been studying clinical and basic research on urological diseases, especially on prostate cancer, and published more than 180 original articles, 130 reviews and 50 chapters of books.

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Tokyo Kosei Nenkin Hospital
Tokyo
Japan
Region: Australia
J. Nikles
The University of Queensland
Salisbury
Australia
Region: Europe
G. Biala (Biography
G. Biala

Prof. GRAŻYNA BIAŁA, Department of Pharmacology with Pharmacodynamics, Medical University of Lublin, Poland Education: Faculty of Pharmacy, Medical University, Lublin, Poland; Master’s degree (highest honor), Department of Biochemistry; Doctoral thesis in pharmacology (highest honor), Department of Pharmacodynamics; Habilitation thesis in Pharmacology (highest honor), idem; since 2010–Full Professor degree, now: the Head of the Chair and Department of Pharmacology and Pharmacodynamics; since 2012 – Vice-Dean of the Faculty of Pharmacy with Medical Analitics Division, Medical University of Lublin, Poland. Research subjects include psychopharmacology, pharmacotherapy and experimental pharmacology.

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Medical University of Lublin
Lublin
Poland
Mario Masarone (Biography
Mario Masarone

Dr Mario Masarone, graduated in Medicine and Surgery at the Second University of Naples in 2004, is a MD specialized in Internal Medicine. He obtained a doctorate (Ph.D.) in Biotechnologies in 2015. Actually is applied as a Post-doc Researcher at the Department of Medicine and Surgery of the University of Salerno (Italy). He has published at the time about 30 paper within the fields of Internal and Emergency Medicine and Hepatology. He is member of the Italian Association for the Study of the Liver (AISF) and European Association for the Study of the Liver (EASL).

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University of Salerno
Salerno
Italy
Region: North America
L. Boccuto (Biography
L. Boccuto

Dr. Boccuto is a clinical geneticist who trained for several years under Professor Neri in Rome with a focus on in hereditary cancer, overgrowth syndromes and intellectual disability (ID) syndromes. Dr. Boccuto is currently an assistant research scientist at the JC Self Research Institute of the Greenwood Genetic Center. His main projects are focused on the study of the genetic causes of autism, ID, and conditions with segmental or generalized overgrowth. He is also characterizing the metabolic profiles of cells from patients with autism, ID and overgrowth, as well as mental disorders such as schizophrenia, ADD/ADHD and Tourette syndrome.

)

Clemson University School of Health Research
Clemson, SC
USA
P. Fu (Biography
P. Fu

Dr Fu is an Associate Professor of Biostatistics at Case Western Reserve University. He has over 15 years of experience in medical research, especially in cancer research. He have received a broad training in mathematics, statistics/biostatistics and computer science in both China and United States. His primary interests include providing advice for researchers in terms of study design, best practice for estimation, diagnostics, and use of appropriate statistical methods to analyze the complex data from pre-clinical and clinical studies. His methodologic research interests are in the areas of survival analysis, study design, measurements with limits of detection, tree-based methods, problem of separation, copula models to estimate the correlation of bivariate failure times and evaluation of diagnostics and agreement. He teaches survival data analysis annually and mentors/advises graduate students in Biostatistics.

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Case Western Reserve University
Cleveland, Ohio
USA

Editorial Board Members:

V. Bar Ad
Thomas Jefferson University Hospital
Philadelphia, PA
USA

J.S. Berek
David Geffen School of Medicine at UCLA
Los Angeles, CA
USA

W. Blackstock
Wake Forest University
Winston-Salem, NC
USA

A.U. Buzdar
The University of Texas
Houston, TX
USA

F. Ciardiello
A. Lanzara Seconda Università degli Studi di Napoli
Napoli
Italy

J. Dingemanse (Biography
J. Dingemanse

Dr. Jasper Dingemanse is currently Vice President and Head Clinical Pharmacology at Actelion Pharmaceuticals Ltd, Switzerland. In this function he is responsible for the Phase I and early Phase II trials of a range of compounds covering a broad spectrum of therapeutic areas (cardiovasculars, central nervous system, infectiology, immunology, respiratory). Previous positions included functions as Senior Director at The Medicines Company and Group Leader in Clinical Pharmacology at F. Hoffmann-La Roche. In addition, Dr. Dingemanse gained experience as Scientific Director at two CROs. He is the author of approximately 250 peer-reviewed articles covering preclinical and clinical pharmacology studies in various fields.

)

Actelion Pharmaceuticals Limited
Allschwil
Switzerland

A. Federico (Biography
A. Federico

Professor Alessandro Federico is Associate Professor in Hepatology and Gastroenterology at the Medicine and Surgery Faculty of Second University of Naples (Italy). He holds a Ph.D. in Digestive and Nutritional Physiopathology from Second University of Naples and he is also Specialist in Gastroenterology and Digestive Endoscopy. The interest field of his research is the role of radical species and nitric oxide in chronic liver and gastrointestinal diseases and the role of food and nutrition in digestive pathology. Notably, Prof. Federico has published more than 140 scientific publications and is a named inventor of 1 issued patent.

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Second University of Naples
Naples
Italy

C. Gridelli (Biography
C. Gridelli

Cesare Gridelli, MD, is currently Chief of Division of Medical Oncology and Director of Department of Oncology/Hematology at the “S.G. Moscati” Hospital, Avellino (Italy. His areas of expertise are lung cancer and cancer in the elderly. He is President of the Italian Association of Thoracic Oncology (AIOT). Dr..). He is author or co-author of more then 750 papers, of which more then 370 extended papers published on international indexed journals , and several chapters of books. His papers have about 16.378 citations on international indexed journals. Dr. Gridelli has an h-index of 62.

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Azienda Ospedaliera S.G. Moscati, Division of Medical Oncology
Avellino
Italy

A. Medford
University of Bristol, Academic Respiratory Unit
Bristol
United Kingdom

T.P. Monath (Biography
T.P. Monath

Tom is currently CSO and COO of BioProtection Systems, the infectious disease subsidiary of NewLink Genetics, where he is leading the development of the most advanced Ebola virus vaccine in partnership with Merck. The vaccine was recently shown to provide 100% efficacy after a single dose in Phase 3. He has over 25 years operating experience in the healthcare biotechnology industry, and is a former partner in the Pandemic and Biodefense Fund at Kleiner Perkins Caufield & Byers. Before joining NewLink, Tom was CMO for Hookipa Biotech, Juvaris and Xcellerex. Between 1992 & 2006, he was CSO and Executive Director of Acambis prior to its acquisition by Sanofi Pasteur, where he directed R & D on vaccines against dengue, Japanese encephalitis, West Nile, yellow fever, Clostridium difficile, and smallpox. The dengue vaccine that he invented, now commercialized by Sanofi (Dengvaxia®), is one of five vaccines he developed that are now licensed or in late Phase III trials.

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Acambis Inc.
Cambridge, MA
USA

D. Naber
Universitätsklinikum Hamburg-Eppendorf
Hamburg
Germany

E. Scarpellini (Biography
E. Scarpellini

Emidio Scarpellini has been Assistant Professor in Internal Medicine at the Sapienza University of Rome, Rome, Italy. He has published 49 papers, many involving gut microbiota modulation and GERD, and was a Rome III Foundation research fellow in Leuven, Belgium in 2009. He graduated as Phd in Physiopathology of metabolism and nutrition in 2013 at Catholic University of Sacred Heart, Rome, Italy and, in Biomedical Sciences in 2014 at KULeuven, Leuven, Belgium. He is a member of the American Gastroenterological Association, the Italian Society of Gastroenterology, and was an investigator on several recent trials investigating new drugs potentially affecting gut microbiota (e.g. antibiotics, probiotics use in functional gastrointestinal disorders), refractory GERD symptoms and reflux pathophysiology.

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Catholic University of Leuven
Leuven
Belgium

P.L. Zinzani ()
University of Bologna
Bologna
Italy

A. Adell (Biography
A. Adell

Dr. Adell leads the research team of Systems Neurobiology at the Institute of Biomedicine and Biotechnology of Cantabria (IBBTEC) in Santander, Spain. He has more than 20 years of experience in the research of the mechanisms of action of antidepressant and antipsychotic drugs. He has a broad background in neurochemistry and neuropharmacology, and pioneered the technique of intracerebral microdialysis for the study of the biochemical effects of antidepressant drugs. Dr. Adell holds a Ph.D. in Biology from the University of Barcelona, Spain. Dr. Adell has written and/or co-authored over 70 original papers, reviews and book chapters.

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Institute of Biomedicine and Biotechnology of Cantabria
Spain

V. Berger
University of Maryland
Baltimore, MD
USA

R. Brentjens (Biography
R. Brentjens

Dr Renier J. Brentjens obtained an MD/PhD (microbiology) from SUNY Buffalo, completed residency in medicine at Yale New Haven Hospital, and a medical oncology fellowship at Memorial Sloan Kettering Cancer Center (MSKCC). Currently, Dr Brentjens is an associate member on the faculty at MSKCC and an attending physician on the leukemia service. Ongoing pre-clinical and clinical research in the focused on the further development of CAR modified T cells designed to overcome the hostile immunosuppressive tumor microenvironment through the generation of “armored CAR T cells.”

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Memorial Sloan Kettering Cancer Center
New York, NY
USA

P. Cahn (Biography
P. Cahn

Pedro Cahn has been working in infectious diseases for the last 45 years and has been involved in the HIV/AIDS arena since 1982. He has served as Chief of Infectious Diseases at the Juan Fernandez Hospital, where he is now Senior Consultant. He is President of Fundación Huésped in Buenos Aires, the largest NGO in Argentina serving patients with and at risk of HIV/AIDS. Dr. Cahn is Professor of Infectious Diseases at the Buenos Aires University Medical School. He is also a Past-President of the International AIDS Society. He is also an external advisor for UNAIDS, the World Health Organization (WHO), the Pan-American Health Organization, UNITAID, Doctors without Borders, as well as a member of the antiretroviral guidelines panel both for WHO and a former member of the guidelines panel of the International Antiviral Society-USA. Dr. Cahn has published more than 190 peer-reviewed papers and book chapters.

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Fundacion Huesped
Buenos Aires
Argentina

V. Cohen
McGill University School of Medicine
Montreal
Canada

K.H. Dragnev
Dartmouth-Hitchcock Medical Center
Hanover, NH
USA

I. Gentile (Biography
I. Gentile

Dr. Ivan Gentile obtained a degree in medicine cum laude from the University of Naples (SUN) and a specialization in Infectious Diseases at the University of Naples "Federico II" with maximum marks (70/70 cum laude). Currently Dr. Gentile is Assistant Professor at University of Naples Federico II. He has published about 80 scientific publications with an overall Impact factor of about 200. The H-index of 22 (source Scopus). He is reviewer for several scientific journals and as a reviewer for the funding of research projects for UK Medical Research Council (MRC).

)

University of Naples "Federico II"
Naples
Italy

R. A. Khalil (Biography
R. A. Khalil

Dr. Raouf Khalil is an MD PhD who is very interested in scientific research. After graduating from Medical School at Cairo University, he received his Masters in Pharmacology from Assiut University, then completed his PhD in Vascular Pharmacology at the University of Miami. Following fellowship training in Vascular Physiology and Molecular Biology at Harvard Medical School, Dr. Khalil joined the faculty at the University of Mississippi Medical Center. He then moved back to Harvard where he is currently Associate Professor at Harvard Medical School and Principal Investigator at Vascular Surgery Research Laboratories at the Brigham and Women's Hospital, Boston, Massachusetts, USA. Dr. Khalil oversees two NIH-funded research projects, and serves on the editorial boards of over 10 journals and as a reviewer for over 140 journals.

)

Brigham and Women's Hospital
Bostan, MA
USA

R. Meredith (Biography
R. Meredith

Ruby F. Meredith, MD, PhD is a Professor of Radiation Oncology at the University of Alabama at Birmingham. She is former Director of Research in that department, and a Senior Scientist at the University of Alabama at Birmingham Comprehensive Cancer Center. Her career includes basic science investigations and involvement in the conduct of scores of clinical trials, including 50 for targeted radionuclide therapy. Her activities are reflected in publications, memberships of scientific associations and she has served on numerous committees. Among her honors and awards is selection for Best Doctor listings > 10 years. More details are at. http://www.uab.edu/medicine/radonc/en/faculty2/ruby-f-meredith-md-phd

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University of Alabama
Bièrmingham, AL
USA

J. Moore
St. Vincents Hospital
Sydney
Australia

R.M. Pluta (Biography
R.M. Pluta

I was born and educated in Warsaw, Poland where I obtained my medical, neurosurgical, doctoral degrees and postdoctoral award in the field of Neurosurgery from the Medical Research Center of Polish Academy of Sciences and the Jerzy and Krystyna Chorobski Fundation. In 1989 I joined the Surgical Neurology Branch, at the National Institute of Neurological Disorders and Stroke, NIH first as International Fogarty Fellow and next as the Senior Researcher and Clinical Associate. In 2010 I joined JAMA Editorial Board as the Fishbein Fellow. In 2009 our patent “Nitrite for vascular diseases” got the “Deal of Distinction” Award. In 2013 I retired from the NIH. I presented near 120 lectures at national and international conferences, over 80 invited lectures at the universities and conferences and published over 120 articles in the leading medical journals.

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National Institutes of Health
Bethesda, MD
USA

D. Tassinari
City Hospital
Rimini
Italy

S.S. Agarwala
University of Pittsburgh Cancer Institute
Pittsburgh, PA
Canada

M.D. Berry
Brandon University
Brandon
Canada

A. Budillon (Biography
A. Budillon

Dr. Budillon graduated in Medicine and passed the Specialty Certification in Oncology at University Federico II, Naples, Italy. He obtained the PhD in Oncology from University G. D’Annunzio of Chieti, Italy, and a Master degree in Health economy, Management and Bioethics. Dr. Budillon is the chief of Experimental Pharmacology, National Cancer Institute G. Pascale, Naples, Italy. He is also Adjunct Professor in Temple University’s College of Science and Technology, Philadelphia, PA, USA, and author of more that 130 publications and of a patent. He is currently Regional Editor of Recent Patents on Anti-Cancer Drug Discovery, published by Bentham Science.

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Istituto Nazionale Tumori- IRCCS G. Pascale
Napoli
Italy

R. Cheung (Biography
R. Cheung

Professor Raymond Cheung is Lee Man-Chiu Professor in Neuroscience, Professor of Neurology at Department of Medicine, The University of Hong Kong, and Director of Acute Stroke Services, Hong Kong West Cluster Hospitals. He is a Fellow of the Royal Colleges of Edinburgh, Glasgow and London, as well as the American Heart Association, American Stroke Association, American Academy of Medicine, European Stroke Organization, Royal Society of Medicine, Hong Kong College of Physicians and Hong Kong Academy of Medicine. He is Past President of both Hong Kong Neurological Society and Hong Kong Stroke Society. His research interests include cerebrovascular disease, advanced and functional neuroimaging, and neuroprotection. He has published 160 journal papers and 26 book chapters.

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The University of Hong Kong
Pokfulam
Hong Kong

D. Cretoiu
'Carol Davila' University of Medicine and Pharmacy
Bucharest
Romania

B. Ensoli (Biography
B. Ensoli

Dr. Ensoli is the Director of the National AIDS Center (Istituto Superiore di Sanità, Rome, Italy). She spent more than 10 years at the NIH in USA, elucidating the mechanisms of HIV pathogenesis and AIDS-associated tumors. Her current interests include also development of HIV/AIDS preventative and therapeutic vaccines. She has coordinated several international and national research programs in Europe and Developing countries. She is a member of the of the ERC Scientific Council, EMBO, and has been Vice-President of the National AIDS Committee of the Italian Ministry of Health (2006 -2015). She has received several national and international awards and authored more than 300 publications and 7 patents.

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National AIDS Center
Rome
Italy

A. Gozzetti (Biography
A. Gozzetti

Dr Alessandro Gozzetti gained his medical degree in 1993 and hematology fellowship in 1997 from Bologna University, Italy. He completed a PhD in oncology in 2001. He worked as research fellow 3 years at University of Chicago at the Molecular Cytogenetic Cancer Center lab. He gained National Scientific Abilitation as Associate Professor in Hematology in 2013. He is actually staff physician at the Division of Hematology of University of Siena, Italy. Dr Gozzetti is Director of the Multiple Myeloma program , CLL program and Hairy cell program and Director of the Molecular Cytogenetic Lab. He published over 130 papers in peer -reviewed Journals.

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Universita degli Studi di Siena
Siena
Italy

M. Markman
University of Texas
Houston, TX
USA

S. Mocellin (Biography
S. Mocellin

Prof. Simone Mocellin obtained his MD degree at the University of Padova, where he specialized in General Surgery in 1998 and he's got a PhD doctorate in Surgical Oncology in 2002. For two years (1999-2001) he worked at the Surgery Branch of the National Cancer Institute of Bethesda (Maryland, USA). Currently he works as consultant surgeon at the Surgical Oncology branch of the Istituto Oncologico Veneto (IOV-IRCCS) of Padova, Italy. He is also professor of surgery at the Dept. Surgery Oncology and Gastroenterology of the University of Padova, Italy. He is the author of more than 160 articles published in peer-review international medical journals. His main interest is surgical oncology with special regard to the surgical treatment and translational research in the fields of cutaneous melanoma, soft tissue sarcomas and gastrointestinal cancers.

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University of Padova
Padova
Italy

F.J. Morales-Olivas (Biography
F.J. Morales-Olivas

F.J. Morales-Olivas, MD, PhD and specialist in Clinical Pharmacology. He has been full professor of Pharmacology and Dean in the Faculty of Medicine of the University of Valencia. Founder and former director of the Pharmacovigilance Center of the Valencian Community. Author of more than 150 scientific publications about experimental and clinical pharmacology. His research interests have included the pharmacology of adrenergic and histaminergic receptors, drug safety, drug use in children, pharmacoepidemiology, and clinical trials. He is currently president of the Instituto Médico Valenciano and the federation of scientific societies of the Valencian Community.

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University of Valencia
Valencia
Spain

M.R. Posner (Biography
M.R. Posner

Dr. Marshall Posner is Professor of Medicine, Medical Director of the Head and Neck Oncology Program, and Associate Director of the Center for Personalized Cancer Therapeutics at the Icahn School or Medicine at Mount Sinai, NY. He has published over 275 peer-reviewed basic laboratory and clinical studies and multiple reviews and abstracts. Dr. Posner has been the principal investigator on numerous clinical trials in head and neck cancer and has reported studies of immunotherapy in pemphigus, HIV, and nasopharynx cancer. He has a major interest in the immunobiology and therapeutics of Human Papillomavirus and oropharynx cancer.

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Dana-Farber Cancer Institute
Boston, MA
USA

E. S-H. Yang (Biography
E. S-H. Yang

Eddy S. Yang, MD, PhD, received his MD and PhD from the University of Miami School of Medicine and continued post-graduate training in the Department of Radiation Oncology at Vanderbilt University as a Holman Pathway Resident Research Scholar. He subsequently joined the University of Alabama at Birmingham (UAB) in 2010 and is currently Professor and Vice Chair of Translational Sciences in the Department of Radiation Oncology. He also holds joint appointments in the departments of cell, developmental, and integrative biology as well as pharmacology and toxicology at UAB. Dr. Yang is the inaugural holder of the ROAR Southeast Cancer Foundation Endowed Chair and Director of the UAB Nanostring Laboratory.

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University of Alabama-Birmingham
Birmingham, AL
USA


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