Nanoparticulate Drug Delivery Sytem for Cancer Therapy: Oppourtunities and Challenges
Priya Patel, Mihir Raval and Navin ShethAffiliation:
Department of Pharmaceutical Sciences, Saurashtra University, Rajkot-360005, Gujarat, India.
AbstractConventional therapy of anticancer drugs shows side effects for this reason it is necessary to develop newer dosage forms such as nanotechnology, to resolve the issues related to the side effects of anticancer drugs. The field of nanotechnology not only resolves the main issue that is, the side effects of anticancer drugs but also provides a promising approach for treatment of cancer. Nanotechnology is the best way to solve the current problems related to cancer therapies due to their size and surface area. As compared to the conventional dosage forms nanoparticulate systems are more effective treatment of cancer due to the prevention of multi drug resistance along with improved therapeutic effects of the anticancer drugs. Liposomes, polymeric nanoparticles, solid lipid nanoparticles and polymer-drug conjugate nanoparticles present a good platform for the treatment of cancer; some of the nanoparticulate dosage forms are already available in the markets and some dosage forms are under research but it is still necessary to do much research in the field of nanotechnology for the treatment of cancer. This review gives information related to the nanotechnology in cancer therapy along with the discussion of patents and advancement of nanoparticles in cancer therapy.
Cancer treatment, nanoparticulate drug delivery system, nanotechnology, nanotechnology and cancer, polymeric nanoparticles.
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