Nanoparticulate Drug Delivery Sytem for Cancer Therapy: Oppourtunities and Challenges
Priya Patel, Mihir Raval and Navin ShethAffiliation:
Department of Pharmaceutical Sciences, Saurashtra University, Rajkot-360005. Gujarat, India.
AbstractConventional therapy of anticancer drugs shows side effects for that it is necessary to developed newer dosage form like nanotechnology to resolve the issues related side effects of anticancer drugs. Field of nanotechnology to resolve the main issues that is side effects of anticancer drugs and provides a promising approach for treatment of cancer. Nanotechnology is the best way to solve the current problems related in cancer therapies due to their size and surface area.As compare to the conventional dosage form nanoparticulate system are more effectively in treatment of cancer due to the prevention of multi drug resistance along with improve the therapeutic effects of the anticancer drugs.Liposomes, polymeric nanoparticles, Solid lipid nanoparticle and polymer-drug conjugate nanoparticles incorporating good platform for treatment of cancer; some of the nanoparticulate dosage form are already available in markets and some dosage form are under research but still necessary to do much research in the field of nanotechnology for the treatment of cancer.This review give information related to the nanotechnology in cancer therapy along with advancement of nanoparticles in cancer therapy.
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