Quinoline – a Promising Fragment in the Search for New Antimalarials

ISSN: 1875-5607 (Online)
ISSN: 1389-5575 (Print)


Volume 15, 14 Issues, 2015


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Mini-Reviews in Medicinal Chemistry

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Quinoline – a Promising Fragment in the Search for New Antimalarials


Mini-Reviews in Medicinal Chemistry, 14(4): 332-344.

Author(s): Beata Gryzło and Katarzyna Kulig

Affiliation: Department of Physicochemical Drug Analysis, Department of Pharmaceutical Chemistry, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland.

Abstract

Malaria continues to be a potentially fatal threat to almost half of the world's population. In the present review, efforts have been made to provide a literature concerning the study of quinoline as a privilege structure for search of new malarials. The review covers advances in that field made in few last years.

Keywords:

Antimalarials, antimicrobial activity, drug design, hybrid molecules, malaria, plasmodium falciparum, quinoline.



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Article Details

Volume: 14
Issue Number: 4
First Page: 332
Last Page: 344
Page Count: 13
DOI: 10.2174/1389557514666140220123226
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