Adhesive Transfer Soft Lithography: Low-Cost and Flexible Rapid Prototyping of Microfluidic Devices

ISSN: 1876-4037 (Online)
ISSN: 1876-4029 (Print)

Volume 7, 4 Issues, 2015

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Micro and Nanosystems

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N.-T. Nguyen
Queensland Micro- and Nanotechnology Centre
QMF building (N74 Room 1.04)
Griffith University
West Creek Road, Nathan Qld 4111

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Adhesive Transfer Soft Lithography: Low-Cost and Flexible Rapid Prototyping of Microfluidic Devices

Micro and Nanosystems, 6(1): 42-49.

Author(s): Seung Hee Jeong, Klas Hjort and Zhigang Wu.

Affiliation: Microsystems technology, Department of Engineering Sciences, Uppsala University, Box-534, The Angstrom Laboratory, SE-751 21, Uppsala, Sweden.


A simple and low-cost approach was proposed for prototyping PDMS based microfluidic devices by transferring adhesive film microstructures onto a flexible substrate as a mould for PDMS replicas. The microstructures were engraved on an adhesive coated film using a commercial cutting plotter and then transferred (or laminated) onto a flexible substrate, allowing for engraved isolated patterns. The proposed technique was demonstrated by a hydrodynamic focusing microfluidic device, having splitting and re-combining sheath channels. The whole processing could be finished within 1 h in a normal laboratory environment. This approach offers an easy, flexible and rapid prototyping of microfluidic and lab-on-a-chip devices to users without expertise in microfabrication. In addition, by minimizing the use of chemicals, the process becomes more environmentally friendly than conventional photolithography based micro-fabrication techniques.


Adhesive transfer, isolated structure replica, microfluidic device, rapid prototyping, soft lithography, tape transfer lithography.

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Article Details

Volume: 6
Issue Number: 1
First Page: 42
Last Page: 49
Page Count: 8
DOI: 10.2174/1876402906666140527000508

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