A Convenient Synthesis of New 2-Cyanomethylthieno[3,2-e][1,2,4]- triazolo[1,5-c]pyrimidine Derivatives

ISSN: 1875-6255 (Online)
ISSN: 1570-1786 (Print)


Volume 11, 10 Issues, 2014


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Letters in Organic Chemistry

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Miguel Yus
Universidad de Alicante Apdo
Alicante
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A Convenient Synthesis of New 2-Cyanomethylthieno[3,2-e][1,2,4]- triazolo[1,5-c]pyrimidine Derivatives

Author(s): Dhiab Jabli, Khaireddine Dridi and Mohamed L. El Efrit

Affiliation: Laboratory of Organic Chemistry, Department of Chemistry, Faculty of Sciences, El Manar University, El Manar II, Tunis 1060, Tunisia and Department of Chemistry, College of Sciences and Arts, Qassim University, Al-Rass, 53, Kingdom of Saudi Arabia.

Abstract

A new series of 2-cyanomethylthienotriazolopyrimidines has been synthesized in good yield through a facile method using substituted aminothiophene-3-carbonitrile as building block and cyanoacetic acid hydrazide as reagent in one framework. The structure of the synthesized compounds was established on the basis of their mass and spectral data.




Keywords: 2-Aminothiophene-3-carbonitrile, iminoethers, iminithieopyrimidin-3-ylamine, cyanoacetic acid hydrazide, thienotriazolopyrimidine.

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Article Details

Volume: 11
Issue Number: 6
First Page: 403
Last Page: 408
Page Count: 6
DOI: 10.2174/1570178611666140311005612
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