Affiliation: Division of Internal Medicine, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, 84000, Israel.
Vitamin D deficiency, a worldwide epidemic has been vastly studied in the last years and was found associated with different medical conditions varying from cancer to immune diseases. In this review article we have proposed that vitamin D is highly correlated with two chronic respiratory diseases, Asthma and COPD using population based and biological studies. The mechanism linking between these respiratory diseases involves numerous agents ranging from cell signaling pathway to anti-inflammatory cytokines. In addition, the role of vitamin D supplementation seems promising especially in the management of Asthma disease.