Update on the Development of TB Vaccines

ISSN: 1873-4316 (Online)
ISSN: 1389-2010 (Print)

Volume 18, 15 Issues, 2017

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Current Pharmaceutical Biotechnology

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Zeno Foldes-Papp
Urban Clinical Center Soltau
University teaching hospital of Hamburg

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Update on the Development of TB Vaccines

Current Pharmaceutical Biotechnology, 14(11): 940-946.

Author(s): Roberto Zenteno-Cuevas.

Affiliation: Instituto de Salud Publica, Universidad Veracruzana, Av. Luis Castelazo Ayala s/n, A.P. 57 Col. Industrial Animas, Xalapa, Veracruz, 91190, Mexico.


Tuberculosis (TB) is an infectious disease caused mainly by members of Mycobacterium tuberculosis complex. In 2012, the WHO estimated 8.7 million new cases and 1.4 million deaths caused by this disease. Under the Millennium Development Goals, the WHO aims to eradicate TB as a public health problem by 2050. However, reaching this goal will require the development and incorporation of new and more effective vaccines that can replace the current BCG vaccine. Much work is therefore ongoing in terms of the development of TB vaccines and more than 10 candidate vaccines are progressing well through the different development stages. The aim of this mini-review is to describe the characteristics of the most promising vaccines, and to give a brief description of some key elements relating to the current and future development of vaccines against TB.


BCG, Development, Tuberculosis, Vaccine.

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Article Details

Volume: 14
Issue Number: 11
First Page: 940
Last Page: 946
Page Count: 7
DOI: 10.2174/1389201014666131226124940
Price: $58
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