A Facile and Quick Synthesis of 9-aryl-substituted-acridines Mediated by DMP

ISSN: 1875-6271 (Online)
ISSN: 1570-1794 (Print)


Volume 11, 6 Issues, 2014


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Prof. Eduardo A Castro
Universidad Nacional de La Plata
Buenos Aires
Argentina


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A Facile and Quick Synthesis of 9-aryl-substituted-acridines Mediated by DMP

Author(s): George Bratulescu

Affiliation: University of Craiova, Faculty of Chemistry, 13 A.I. Cuza, 200585 Craiova, Romania.

Abstract

An unexpected three components reaction was developed for acridine synthesis in solvent free medium. The reaction is carried out with commercial reagents using of microwaves in a heterogeneous medium in presence of zinc chloride and 2,2-dimethoxypropane (DMP) as water scavenger. Principal advantages of the method are: short time, high yields and easy work-up.

Keywords: Aromatic acids, acridine, bernthsen reaction, diphenylamine, DMP, water scavenger.

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Article Details

Volume: 10
Issue Number: 6
First Page: 947
Last Page: 950
Page Count: 4
DOI: 10.2174/157017941006140206104352
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