A Facile and Quick Synthesis of 9-aryl-substituted-acridines Mediated by DMP
University of Craiova, Faculty of Chemistry, 13 A.I. Cuza, 200585 Craiova, Romania.
AbstractAn unexpected three components reaction was developed for acridine synthesis in solvent free medium. The reaction is carried out with commercial reagents using of microwaves in a heterogeneous medium in presence of zinc chloride and 2,2-dimethoxypropane (DMP) as water scavenger. Principal advantages of the method are: short time, high yields and easy work-up.
Aromatic acids, acridine, bernthsen reaction, diphenylamine, DMP, water scavenger.
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