Tetrapyrrolic Macrocycles: Potentialities in Medical Imaging Technologies

ISSN: 1875-6271 (Online)
ISSN: 1570-1794 (Print)

Volume 14, 8 Issues, 2017

Download PDF Flyer

Current Organic Synthesis

This journal supports open access

Aims & ScopeAbstracted/Indexed in

Ranking and Category:
  • 31st of 59 in Chemistry, Organic

Submit Abstracts Online Submit Manuscripts Online

L.-N. He
Nankai University
P.R. China

View Full Editorial Board

Subscribe Purchase Articles Order Reprints

Current: 2.05
5 - Year: 2.19

Tetrapyrrolic Macrocycles: Potentialities in Medical Imaging Technologies

Current Organic Synthesis, 11(1): 127-140.

Author(s): Mário J.F. Calvete, Ana V.C. Simoes, César A. Henriques, Sara M.A. Pinto and Mariette M Pereira.

Affiliation: Centro de Química de Coimbra, Departamento de Química, Universidade de Coimbra, Rua Larga, 3004-535, Coimbra, Portugal.


The field of imaging science is growing immensely, with the emergence of “noninvasive” in vivo imaging technologies and imaging probes like Positron Emission Tomography (PET), Fluorescence Imaging (FI) and Magnetic Resonance Imaging (MRI), to observe events at molecular and cellular levels, and consequently to speed up drug development processes. For instance, the imaging of cancer specific molecular targets ought to permit precocious diagnosis and superior evaluation to oncology patients. Porphyrins and their derivatives (or related compounds, like phthalocyanines) represent one of the oldest, most widely studied chemical structures, both in nature and in biomedical applications. They display intrinsic affinity for tumor localization and their well-portrayed photophysical and photosensitizing properties can lead to their potential use as sensitizer in a variety of in vivo imaging technologies. This contribution will review recent developments involving tetrapyrrolic -based sensitizers for cancer detection, with emphasis on PET, FI and MRI technologies.


Porphyrins, phthalocyanines, FI imaging, MRI imaging, PET imaging, theranostics.

Download Free Order Reprints Order Eprints Rights and Permissions

Article Details

Volume: 11
Issue Number: 1
First Page: 127
Last Page: 140
Page Count: 14
DOI: 10.2174/15701794113106660090
Global Biotechnology Congress 2017Drug Discovery and Therapy World Congress 2017

Related Journals

Related eBooks

Webmaster Contact: urooj@benthamscience.org Copyright © 2017 Bentham Science