Wnt Signaling Pathway in Schizophrenia
CNS & Neurological Disorders - Drug Targets, 13
): 755-764.Author(s): Yanmin Peng
, Yifeng Xu
and Donghong Cui
Key Laboratory of Translational Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 3210 Humin Rd, Shanghai, 200030, China.
AbstractThe Wnt signaling pathway is one of the crucial signaling pathways that regulate many aspects of central nervous system. In this review, we tempt to depict an overall picture of the Wnt signaling with its multitude of roles in schizophrenia. If the Wnt signaling pathway plays a crucial role in the pathogenesis of schizophrenia as we suggest, a better understanding of the Wnt pathway might contribute to developing new and more effective tools for diagnosis and treatment of schizophrenia.
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