Current View from Alzheimer Disease to Type 2 Diabetes Mellitus

ISSN: 1996-3181 (Online)
ISSN: 1871-5273 (Print)


Volume 13, 10 Issues, 2014


Download PDF Flyer




CNS & Neurological Disorders - Drug Targets

Formerly: Current Drug Targets - CNS & Neurological Disorders

Aims & ScopeAbstracted/Indexed in

Ranking and Category:
  • 96th of 254 in Pharmacology & Pharmacy

Submit Abstracts Online Submit Manuscripts Online

Editor-in-Chief:
Stephen D. Skaper
Department of Pharmaceutical and Pharmacological Sciences
University of Padova
Padova
Italy


View Full Editorial Board

Subscribe Purchase Articles Order Reprints

Current: 2.702
5 - Year: 3.298

Current View from Alzheimer Disease to Type 2 Diabetes Mellitus

Author(s): Mahmood Rasool, Arif Malik, Aamer M. Qazi, Ishfaq A. Sheikh, Abdul Manan, Sumaira Shaheen, Mahmood H. Qazi, Adeel G. Chaudhary, Adel M. Abuzenadah, Muhammad Asif, Mohammed H. Alqahtani, Zafar Iqbal, Munvar M. Shaik, Siew H. Gan and Mohammad A. Kamal

Affiliation: Center of Excellence in Genomic Medicine Research, Post Box No. 80216, King Abdulaziz University, Jeddah 21589, Saudi Arabia.

Abstract

Alzheimer’s disease (AD) is a neurodegenerative disorder that leads to memory problems. It has been associated with type 2 diabetes mellitus at both the molecular and biochemical level. Pancreatic cells have molecular similarities to the brain at the transcriptomic and proteomic levels. Several genes have been reported to be responsible for both AD and diabetes. Currently, no proper treatment is available but various therapeutic approaches are utilized worldwide for the management of these disorders and may be nanoparticles and herbal treatment of Bacopa monnieri will make promise for the treatment of AD in future. The formation of amyloids in neurons and the formation of amylin in pancreatic cells are potential links between these two disorders, which can be silent killers.

Keywords: Neurodegenerative, type 2 diabetes mellitus, pancreatic cells, amyloid.

Purchase Online Rights and Permissions

  
  



Article Details

Volume: 13
Issue Number: 3
First Page: 533
Last Page: 542
Page Count: 10
DOI: 10.2174/18715273113126660167
Advertisement

Related Journals




Webmaster Contact: urooj@benthamscience.org Copyright © 2014 Bentham Science