A Novel Strategy for Synthesis of Gold Nanoparticle Self Assemblies

ISSN: 1875-6786 (Online)
ISSN: 1573-4137 (Print)


Volume 10, 6 Issues, 2014


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A Novel Strategy for Synthesis of Gold Nanoparticle Self Assemblies

Author(s): Jyoti Verma, Sumit Lal, Henk A. Van Veen and Cornelis J. F. Van Noorden

Affiliation: Department of Medicine, Harvard Medical School, Boston, MA, USA.

Abstract

Gold nanoparticle self assemblies are one-dimensional structures of gold nanoparticles. Gold nanoparticle self assemblies exhibit unique physical properties and find applications in the developement of biosensors. Methodologies currently available for lab-scale and commercial synthesis of gold nanoparticle self assemblies are complex. These methods are often multistep involving linker nanoparticle conjugation steps and external stimuli treatment steps. Here we present a simple method for synthesis of gold nanoparticle self assemblies. The method involves surfactant-free synthesis of gold nanoparticles, washing of gold nanoparticles with distilled water and irradiation of gold nanoparticles with glow discharge plasma. Thus synthesized gold nanoparticle self assemblies were characterized using electron microscopy and ultraviolet and visible light spectroscopy. Results show that washing with distilled water and irradiation with glow discharge plasma induces assembling of gold nanoparticles into multimers, chain-like structures and networks. Our synthesis method is unique in that it provides full control on the extent of self assembly and at the same time is simple and economical. Our synthesis method will facilitate lab-scale and commercial synthesis of gold nanoparticle self assemblies, which in turn, will promote the application of self assemblied gold nanoparticles in development of novel biosensors, drug delivery platforms, lab-on-a-chip platforms and a variety of other nano-scale medical devices.

Keywords: Chain-like structure and nanoparticle network, gold, multimer, nanoparticle, self assembly

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Article Details

Volume: 10
First Page: 1
Last Page: 6
Page Count: 6
DOI: 10.2174/1573413710666140526232145
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