Potential Effects of Cannabidiol as a Wake-Promoting Agent

ISSN: 1875-6190 (Online)
ISSN: 1570-159X (Print)


Volume 12, 6 Issues, 2014


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Current Neuropharmacology

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Potential Effects of Cannabidiol as a Wake-Promoting Agent

Author(s): Eric Murillo-Rodriguez, Andrea Sarro-Ramirez, Daniel Sanchez, Stephanie Mijangos-Moreno, Alma Tejeda-Padron, Alwin Poot-Ake, Khalil Guzman, Elda Pacheco-Pantoja and Oscar Arias-Carrion

Affiliation: Laboratorio de Neurociencias Moleculares e Integrativas, Escuela de Medicina, Division Ciencias de la Salud, Universidad Anahuac Mayab, Carretera Merida-Progreso Km, 15.5, A.P. 96 Cordemex C.P. 97310, Merida, Yucatan, Mexico.

Abstract

Over the last decades, the scientific interest in chemistry and pharmacology of cannabinoids has increased. Most attention has focused on Δ9-tetrahydrocannabinol (Δ9-THC) as it is the psychoactive constituent of Cannabis sativa (C. sativa). However, in previous years, the focus of interest in the second plant constituent with non-psychotropic properties, cannabidiol (CBD) has been enhanced. Recently, several groups have investigated the pharmacological properties of CBD with significant findings; furthermore, this compound has raised promising pharmacological properties as a wake-inducing drug. In the current review, we will provide experimental evidence regarding the potential role of CBD as a wake-inducing drug.

Keywords: Dopamine, hypothalamus, marijuana, sleep, sleepiness.

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Article Details

Volume: 12
Issue Number: 3
First Page: 269
Last Page: 272
Page Count: 4
DOI: 10.2174/1570159X11666131204235805
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