BoronicAcid-based Enzyme Inhibitors: A Review of Recent Progress

ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)

Volume 21, 38 Issues, 2014

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Current Medicinal Chemistry

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Atta-ur-Rahman, FRS
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Kings College
University of Cambridge

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BoronicAcid-based Enzyme Inhibitors: A Review of Recent Progress

Author(s): W u Zhongyu, Hao Fang and X u Wenfang

Affiliation: Institute of Materia Medica, Shandong Academy of Medical Sciences, No. 18877 Jingshi Road, Ji’nan , Shandong 250062, China


Since Bortezomib was approved by US FDA as the first drug to treat multiple myeloma, various boronic acid compounds have been developed as enzyme inhibitors. This paper reviewed the progress of boronic acid-based inhibitors against enzymes including proteasome, serine protease, HDACs and other enzymes in the past decade

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Article Details

Volume: 21
First Page: 1
Last Page: 1
Page Count: 1
DOI: 10.2174/0929867321666140601200803

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