Helicobacter pylori: An Overview on Antimicrobials and Drug Delivery Systems for its Eradication

ISSN: 1875-5704 (Online)
ISSN: 1567-2018 (Print)

Volume 12, 6 Issues, 2015

Download PDF Flyer

Current Drug Delivery

Aims & ScopeAbstracted/Indexed in

Submit Abstracts Online Submit Manuscripts Online

Istvan Toth
School of Pharmacy,University of Queensland
Brisbane, 4072

View Full Editorial Board

Subscribe Purchase Articles Order Reprints

Current: 1.478

Helicobacter pylori: An Overview on Antimicrobials and Drug Delivery Systems for its Eradication

Current Drug Delivery, 11(3): 306-312.

Author(s): Sally A. El-Zahaby, Abeer A. Kassem and Amal H El-Kamel.

Affiliation: Department of Pharmaceutics, Pharos University in Alexandria, Canal El- Mahmoudia Street, Smouha. Alexandria, Egypt, P.O. Box 37, Sidi Gaber, Alexandria 21311, Egypt.


Since the discovery of Helicobacter pylori (H. pylori) in the early 1980s, its eradication has been one of the most important global challenges in gastroenterology. Various circumstances make the treatment with antimicrobials particularly difficult. One problem has been that antibiotics commonly used were designed for the treatment of infections throughout the body rather than for delivering high concentrations locally within the stomach. Many gastroretentive dosage forms were developed in order to eradicate the infection, yet additional advancements are still needed to eliminate the infection completely and decrease its prevalence worldwide. An overview on different antimicrobials and a literature survey about different drug delivery systems used in eradication of H. pylori infection are presented in this review.


Gastroretentive, Helicobacter pylori, Mucopenetration, Specific targeting.

Purchase Online Order Reprints Order Eprints Rights and Permissions

Article Details

Volume: 11
Issue Number: 3
First Page: 306
Last Page: 312
Page Count: 7
DOI: 10.2174/1567201811666140327145049
Orphan Drugs and Rare Diseases Conference

Related Journals

Webmaster Contact: urooj@benthamscience.org Copyright © 2015 Bentham Science