A Practical Guide to the Treatment of Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF)

ISSN: 1875-6557 (Online)
ISSN: 1573-403X (Print)


Volume 10, 4 Issues, 2014


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Current Cardiology Reviews

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Editor-in-Chief:
Fei Lu
University of Minnesota Medical School
Minneapolis, MN 55455
USA


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A Practical Guide to the Treatment of Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF)

Author(s): Brent N. Reed and Carla A. Sueta

Affiliation: University of North Carolina, 160 Dental Circle, CB 7075, Chapel Hill, NC 27599-7075

Abstract

This review will outline the management of patients with symptomatic systolic or heart failure with reduced ejection fraction (HFrEF), i.e., those with structural heart disease and previous or current symptoms. Determination of volume status and appropriate diuretic administration is important in heart failure management. Inhibition of the renin-angiotensin-aldosterone and sympathetic nervous systems improves survival and decreases hospitalizations in patients with systolic or reduced ejection fraction HF (HFrEF). Beta blockers and aldosterone antagonists improve ejection fraction. Indications for additional agents including nitrates plus hydralazine, digoxin, statins, omega 3 polyunsaturated fatty acids, anticoagulants, and antiarrhythmics will be discussed. Choice of agents, dose-related effects, strategies to minimize adverse effects, and medications to avoid will be presented

Keywords: ACE Inhibitor, aldosterone antagonist, angiotensin receptor blocker, beta blocker, heart failure with reduced ejection fraction, systolic heart failure

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Article Details

Volume: 9
First Page: 1
Last Page: 10
Page Count: 10
DOI: 10.2174/1574884708666131117125508
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